A group of research lab monkeys escaped captivity in Mississippi as the truck carrying them overturned on Tuesday. The monkeys were on their way to a Tulane University research center in New Orleans from the University’s Biomedical Research Center in Louisiana. At first, officials worried the monkeys might have dangerous sicknesses, like herpes. However, Tulane University quickly said the animals were healthy and disease-free. They confirmed the monkeys had not been near any germ that could cause an illness. Videos of the crash on Interstate 59 showed monkeys crawling in the grass next to broken wooden cages. So far, 14 monkeys have been found, 5 died, while 2 are still at large and the search continues. While the health officials assured people that there were no possible disease outbreaks, questions about ethical considerations and risks that come with animal testing have been brought up. Why Are Monkeys Used In Medical Research? According to the European Animal Research Association (EARA), scientists generally use animals like mice and rats much more than monkeys. However, monkeys, also called non-human primates (NHPs), are sometimes needed because their bodies are the most like human bodies. This means that for some diseases, mice and rats just aren't good enough models to show how a treatment will work in a person. The Understanding Animal Research UK Organization explains that the most commonly used monkeys in research are Rhesus macaques, Cynomolgus macaques, and Common Marmosets. Old-world monkeys, which are Macaques, share 94% genetic code with humans while the new-world monkeys which are Marmosets, share 91.7% genetic code with humans. The EARA expands that monkeys are especially important for research on:Brain diseases such as Alzheimer's and Parkinson's.Reproduction (like developing IVF).Infections where a person's body reacts very differently from a rodent's.New surgical techniques like organ transplants.Even in Europe, which has strict rules to protect lab animals, experts agree that while the goal is to stop using monkeys completely, a limited number are still necessary right now for key studies on the immune system and brain diseases. What Are The Risks Involved With Animal Research? The Hastings Center for Bioethics explains that despite being used for research and discovering new treatments, almost 100 percent of new drugs for Alzheimer's have failed over many years. Some scientists point out that rhesus monkeys don't naturally get the full disease, the way humans do. This brings up a moral question: Are we using these animals because science truly requires it, or is it simply the easiest option? When animal research doesn't result in a cure for people, which is called a "translational failure", it means the lives of these conscious, feeling animals are wasted in experiments that probably won't work. This failure is also bad for humans, who face risks in trials based on weak animal data and who keep waiting for medical breakthroughs that never arrive. Are Monkey-Based Researches Accurate? The accuracy of these tests and research has been questioned before. According to a 2023 explainer published in the Nature, a scientist named Dr. Jonah Sacha, who studies the body's immune system and how it fights disease, bought a group of monkeys for his research on infectious diseases. Before starting his studies, Dr. Sacha followed standard safety procedures and took chest X-rays of all the monkeys. This is like giving them a quick check-up. During this screening, he made a worrying discovery: one of the monkeys was sick. This monkey was carrying the bacteria that causes tuberculosis (TB). Even though the monkey wasn't showing signs of being sick, the X-ray showed it had latent TB. "Latent" means the TB germs were hidden or sleeping inside its body, ready to cause the full, active disease later on. This finding was a major problem because TB is highly contagious and could have easily spread to the other monkeys, and potentially even to the lab workers, creating a dangerous situation. The researchers explain that it can lead to disruptions in the experiments and unreliable data. Can Monkeys Be Replaced For Research? The EARA explains that monkeys are currently required to test new drug safety because no other animal or lab model, like "organs-on-a-chip," can fully replicate the human body's complexity. Banning these studies would simply move them outside the EU, as global safety rules demand them. For specific human diseases, especially in brain science, monkeys remain the only suitable model, and replacements are not yet ready. Researchers are currently working on ways to remove the need for animals in health research, however overturning the status quo may take a few more years.
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