Health and Me

Riya Baibhawi

Blood Test That Can Detect 12 Types Of Cancer To Go On Trial In UK

A new AI-powered <span>blood test</span> that can detect 12 types of <span><a href="https://www.healthandme.com/health/cancer">cancer</a></span> is to be tested on <span>NHS</span> patients. Using this test, experts would now be able to detect cancerous cells in people much before the symptoms appear. The trial, conducted on 8,000 patients, will analyse blood samples for tiny fragments of genetic material released by tumours. 

The test called miONCO-Dx, was created using data from 20,000 patients. Initial tests have produced promising results, having shown that it can detect 12 of the most lethal and common cancers, including bowel cancer, at an early stage, with over 99% accuracy. With no other trial currently working in the same way, this is a world-leader and will support in placing Britain at the forefront of revolutionising healthcare. Notably, the UK government has awarded £2.4m to run the trial of the genetic test, which was developed by the University of Southampton and the biotech startup Xgenera. 

The test was created by Xgenera, in collaboration with the University of Southampton. As little as 10 drops of blood are all that's needed to detect up to 12 common cancers. The test works by measuring the microRNA in a blood sample and using AI to identify if cancer is present and, if so, where it is located in the body.  

Lung, gastric, prostate, oesophageal, liver, bladder, ovarian, bowel, pancreatic and breast cancers–as well as bone and soft tissue sarcoma and a type of brain tumour. The Department of Health said the test was now ready for the "validation and verification" stage.

Professor Sir Stephen Powis, NHS England's national medical director, said: "This blood test has the potential to help us detect bowel cancer earlier and reduce the need for invasive tests, and the next step in this trial will now be vital in gathering further evidence on its effectiveness and how it could work in practice."

A blood test is a simple medical procedure used to check various health conditions. Here's how it is typically conducted:

1. Preparation: Depending on the test, you may be asked to fast for 8–12 hours. The healthcare provider will explain any specific instructions.

2. Collection: You’ll usually be seated or lying down. A healthcare professional will tie a tourniquet around your upper arm to make the veins more visible. The inside of your elbow is the most common site for drawing blood.

3. Cleaning: The area is cleaned with an antiseptic to reduce the risk of infection.

4. Drawing Blood: A sterile needle is inserted into the vein, and blood is collected into one or more vials or tubes.

5. Post-collection: Once enough blood is collected, the needle is removed, and a cotton ball or bandage is applied to stop any bleeding.

6. Processing: The blood samples are then sent to a lab for analysis.

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A new AI-powered blood test that can detect 12 types of cancer is to be tested on NHS patients. Using this test, experts would now be able to detect cancerous cells in people much before the symptoms appear. The trial, conducted on 8,000 patients, will analyse blood samples for tiny fragments of genetic material released by tumours. The test called miONCO-Dx, was created using data from 20,000 patients. Initial tests have produced promising results, having shown that it can detect 12 of the most lethal and common cancers, including bowel cancer, at an early stage, with over 99% accuracy. With no other trial currently working in the same way, this is a world-leader and will support in placing Britain at the forefront of revolutionising healthcare. Notably, the UK government has awarded £2.4m to run the trial of the genetic test, which was developed by the University of Southampton and the biotech startup Xgenera. How Does It Work?The test was created by Xgenera, in collaboration with the University of Southampton. As little as 10 drops of blood are all that's needed to detect up to 12 common cancers. The test works by measuring the microRNA in a blood sample and using AI to identify if cancer is present and, if so, where it is located in the body.  What Cancers Will It Detect?Lung, gastric, prostate, oesophageal, liver, bladder, ovarian, bowel, pancreatic and breast cancers–as well as bone and soft tissue sarcoma and a type of brain tumour. The Department of Health said the test was now ready for the "validation and verification" stage.Professor Sir Stephen Powis, NHS England's national medical director, said: "This blood test has the potential to help us detect bowel cancer earlier and reduce the need for invasive tests, and the next step in this trial will now be vital in gathering further evidence on its effectiveness and how it could work in practice."How Is A Blood Test Conducted?A blood test is a simple medical procedure used to check various health conditions. Here's how it is typically conducted:1. Preparation: Depending on the test, you may be asked to fast for 8–12 hours. The healthcare provider will explain any specific instructions.2. Collection: You’ll usually be seated or lying down. A healthcare professional will tie a tourniquet around your upper arm to make the veins more visible. The inside of your elbow is the most common site for drawing blood.3. Cleaning: The area is cleaned with an antiseptic to reduce the risk of infection.4. Drawing Blood: A sterile needle is inserted into the vein, and blood is collected into one or more vials or tubes.5. Post-collection: Once enough blood is collected, the needle is removed, and a cotton ball or bandage is applied to stop any bleeding.6. Processing: The blood samples are then sent to a lab for analysis.

blood test that can detect 12 types of cancer to go on trial in uk

Aarushi Bhadury

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THIS Simple 10-Second Test Could Predict Dementia Risk Early

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The recent decline in the beloved actor <span>Bruce Willis</span>’ health has affected many people. The legendary actor has now been struggling with frontotemporal dementia for the past three years. His wife, Emma Hemmings has been vocal about caregivers and their health, has been sharing updates with his fans. In a recent interview with ABC News, she shared that Bruce is still mobile and in good health, “It's just his brain that is failing him” 

<h2><span rel="noindex">Bruce Willis Dementia History</span>: Diagnosis And Initial Struggles</h2>

In 2023, Willis's family publicly announced that he had been diagnosed with frontotemporal dementia (FTD). This type of dementia can change a person's personality and behavior. <span>Emma Heming Willis</span> has written a new book, "The Unexpected Journey: Finding Strength, Hope, and Yourself on the Caregiving Path," to share her family's experience. 

She described her early days as a caregiver as feeling like she had to do everything alone. She would stay up at night to make sure her husband was safe and would avoid social gatherings to make things easier for him. This experience led her to become an advocate for other caregivers, and she hopes her book can be a helpful guide for them. 

<h2>How Does Caring For Dementia Patients Affect Caregivers? </h2>

Caregivers are often overlooked among people to be care for. According to a 2022 study published in the International Psychogeriatrics journal, in the U.S. alone, over 15.5 million people provide unpaid care for someone with dementia. Globally, the amount of time spent on this care is equal to more than 40 million full-time jobs, and this number is expected to grow. 

<h2>Why Caregivers Need To Be The Ones Cared For As Well </h2>

Caregivers for people with dementia are often called the "invisible second patients" because they face so many challenges themselves. While some caregivers feel a sense of pride or satisfaction, many also experience high levels of stress, burnout, anxiety, and depression. 

Studies show that nearly half of all caregivers feel a significant burden, and about one-third show signs of depression and anxiety. This emotional stress can lead to physical health problems, like chronic inflammation, which increases the risk of heart disease and other illnesses. 

Recently, some experts have suggested changing the term "caregiver" to "care partner." This change highlights the idea that caring for someone with a long-term illness should be a partnership. This new term recognizes that the person with the disease also plays an important role in their own care. While this is a great idea, it can be hard to apply to people with advanced dementia who can no longer make their own decisions. 

<h2>How Can We Tackle Caregiver’s Fatigue? </h2>

The 2022 study explained that a collection of seven new studies from different countries looked at various aspects of caregiving for people with dementia. 

An Irish study found that caregivers for people with dementia are much more likely to feel overwhelmed than those caring for older people with other health issues. 

<h4>Preventing Nursing Home Admission </h4>

A Norwegian study found that when caregivers feel stressed and unable to cope, it is a major reason for moving a person with dementia into a nursing home sooner. 

An international study explored the role of compassion—both for oneself and for others—in helping caregivers. 

Researchers in the UK reviewed studies on the positive side of caregiving, like a caregiver's resilience and sense of accomplishment. 

A Danish study developed a new tool to help identify what kind of support a caregiver needs. This could help create personalized support plans. 

A Spanish study showed that a nine-month exercise program had a positive effect on caregivers, reducing their stress and risk of depression. 

<h4>Making Interventions Accessible </h4>

A U.S. study found that caregivers were willing to pay for programs that taught them skills to better manage dementia symptoms. This suggests new ways to make these helpful programs available to more families. 

Bruce Willis Health Update

bruce willis

Bruce Willis Dementia

Bruce Willis Dementia History

Bruce Willis Disease

Dementia Care

emma heming willis

diane sawyer

bruce willis wife

The recent decline in the beloved actor Bruce Willis’ health has affected many people. The legendary actor has now been struggling with frontotemporal dementia for the past three years. His wife, Emma Hemmings has been vocal about caregivers and their health, has been sharing updates with his fans. In a recent interview with ABC News, she shared that Bruce is still mobile and in good health, “It's just his brain that is failing him” Bruce Willis Dementia History: Diagnosis And Initial StrugglesIn 2023, Willis's family publicly announced that he had been diagnosed with frontotemporal dementia (FTD). This type of dementia can change a person's personality and behavior. Emma Heming Willis has written a new book, "The Unexpected Journey: Finding Strength, Hope, and Yourself on the Caregiving Path," to share her family's experience. She described her early days as a caregiver as feeling like she had to do everything alone. She would stay up at night to make sure her husband was safe and would avoid social gatherings to make things easier for him. This experience led her to become an advocate for other caregivers, and she hopes her book can be a helpful guide for them. How Does Caring For Dementia Patients Affect Caregivers? Caregivers are often overlooked among people to be care for. According to a 2022 study published in the International Psychogeriatrics journal, in the U.S. alone, over 15.5 million people provide unpaid care for someone with dementia. Globally, the amount of time spent on this care is equal to more than 40 million full-time jobs, and this number is expected to grow. Why Caregivers Need To Be The Ones Cared For As Well Caregivers for people with dementia are often called the "invisible second patients" because they face so many challenges themselves. While some caregivers feel a sense of pride or satisfaction, many also experience high levels of stress, burnout, anxiety, and depression. Studies show that nearly half of all caregivers feel a significant burden, and about one-third show signs of depression and anxiety. This emotional stress can lead to physical health problems, like chronic inflammation, which increases the risk of heart disease and other illnesses. Recently, some experts have suggested changing the term "caregiver" to "care partner." This change highlights the idea that caring for someone with a long-term illness should be a partnership. This new term recognizes that the person with the disease also plays an important role in their own care. While this is a great idea, it can be hard to apply to people with advanced dementia who can no longer make their own decisions. How Can We Tackle Caregiver’s Fatigue? The 2022 study explained that a collection of seven new studies from different countries looked at various aspects of caregiving for people with dementia. Caregiver Burden An Irish study found that caregivers for people with dementia are much more likely to feel overwhelmed than those caring for older people with other health issues. Preventing Nursing Home Admission A Norwegian study found that when caregivers feel stressed and unable to cope, it is a major reason for moving a person with dementia into a nursing home sooner. The Power of Compassion An international study explored the role of compassion—both for oneself and for others—in helping caregivers. Focusing on the Positive Researchers in the UK reviewed studies on the positive side of caregiving, like a caregiver's resilience and sense of accomplishment. Finding the Right Support A Danish study developed a new tool to help identify what kind of support a caregiver needs. This could help create personalized support plans. Exercise as a Solution A Spanish study showed that a nine-month exercise program had a positive effect on caregivers, reducing their stress and risk of depression. Making Interventions Accessible A U.S. study found that caregivers were willing to pay for programs that taught them skills to better manage dementia symptoms. This suggests new ways to make these helpful programs available to more families.  

Bruce Willis Health Update, 'It's Just His Brain That Is Failing Him.' Wife Emma Shares

bruce willis health update, 'it's just his brain that is failing him.' wife emma shares

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Wastewater Surveillance In India: Can Sewage Help Detect Viruses Before Outbreaks?

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The Indian Council of Medical Research (ICMR) is embarking on one of its most ambitious public health projects yet—expanding wastewater surveillance from five cities to 50 within the next six months. The program will track 10 different viruses, including influenza strains and pathogens responsible for fever, diarrheal illnesses, encephalitis, and respiratory infections.

The goal is simple but powerful: to create an early warning system for outbreaks before they overwhelm hospitals. For India, a country with a vast and densely packed population, the ability to detect viral threats at the community level could be transformative. For the rest of the world, the project provides a case study of how wastewater-based epidemiology (WBE) can help governments prepare for and potentially prevent pandemics.

<h2>What Is Wastewater Surveillance?</h2>

Wastewater surveillance, also called Wastewater-Based Epidemiology (WBE), is the practice of analyzing sewage for fragments of viruses, bacteria, and other pathogens that people shed when they use toilets, sinks, or showers.

An infected person symptomatic or not will excrete viral particles through stool, urine, or even when washing. These particles end up in community sewage. When scientists collect and test these samples, they can detect infection trends in entire populations, sometimes weeks before clinical cases surface in hospitals.

Unlike hospital-based testing, which only captures people who seek medical care, wastewater surveillance gives a panoramic view of community health, including those who are asymptomatic, undiagnosed, or reluctant to get tested.

<h2>Why India Is Betting Big on Sewage Science?</h2>

Currently, India uses wastewater surveillance to monitor COVID-19 and polio. But with ICMR’s expansion plan, the program will track up to 10 viruses. Among them: avian influenza viruses and pathogens associated with acute encephalitis syndrome, diarrheal outbreaks, and respiratory infections.

This move isn’t just about academic curiosity. It’s about preparedness. India, like many other countries, is witnessing a rise in emerging and re-emerging pathogens fueled by rapid urbanization, climate shifts, increased human-animal interaction, and dense living conditions. With its massive population and vulnerable healthcare infrastructure, early detection is not optional, it’s essential.

The scaling up from five cities to 50 represents a tenfold leap in capacity, one that could significantly strengthen India’s ability to anticipate outbreaks and allocate resources before a crisis spirals.

<h2>How Wastewater Surveillance Process Works?</h2>

The science behind wastewater surveillance follows a clear workflow:

Pathogen Shedding – People infected with a virus shed particles into sewage through waste or while washing.

Collection – Samples are taken from untreated sewage at pumping stations or before treatment plants.

Laboratory Testing – Viral fragments (RNA/DNA) are extracted and tested using advanced molecular methods.

Data Analysis – Trends in viral load are mapped, typically providing a snapshot of community infections within 5–7 days.

Public Health Action – Authorities can respond with outbreak alerts, vaccination drives, and resource mobilization.

In short, wastewater turns into a real-time diagnostic tool—not for individuals, but for entire neighborhoods and cities.

<h2>Was COVID-19 First Detected Through Wastewater Surveillance?</h2>

If there’s one proof of concept for WBE, it’s the COVID-19 pandemic. In India, a study from Mumbai showed the SARS-CoV-2 virus was detectable in wastewater up to three weeks before clinical diagnoses surged. In Pune, scientists detected the XBB strain months ahead of physicians reporting the first confirmed cases.

Across the world, from Sydney to San Diego, cities leveraged wastewater as an important gauge of viral spread, enabling policymakers to coordinate with greater precision by timing restrictions, calibrating testing, or initiating vaccination campaigns.

This forecasting ability is precisely why India's growth is important. Picking up on early warning signs in sewage might be the difference between a localized outbreak and a national crisis.

<h2>How Does Wastewater Surveillance Addressing More Than Just Viruses?</h2>

Perhaps the most underestimated use for wastewater monitoring is to monitor antimicrobial resistance (AMR)—an invisible international threat that might render many antibiotics obsolete.

India already has an AMR surveillance program in place through a network of 60 hospitals tracking which medicines are effective against which infections.But this only captures patients who make it to hospitals. Wastewater surveillance can reveal resistance patterns at the community level, detecting resistant pathogens carried by people who never seek treatment.

Given projections that AMR could kill 10 million people annually worldwide by 2050, this kind of broad, real-world data is critical.

<h2>How Wastewater Surveillance Can Predict Viral Outbreaks?</h2>

India’s program is ambitious, but it’s part of a larger global shift. The U.S. Centers for Disease Control and Prevention (CDC) already uses wastewater to monitor COVID-19 and other pathogens. In Australia, Dr. Jiaying Li and her team at the University of Sydney developed wastewater methods to track not only viruses but also “forever chemicals” and illicit drug residues, showing the technique’s versatility.

These international examples highlight why public health experts call WBE the “stethoscope of cities.” It listens to what individuals may not yet know about their health and helps leaders act before hospitals get overwhelmed.

For India, timing is everything. The country has weathered devastating outbreaks—from the 2009 H1N1 flu to COVID-19’s Delta surge—and its public health infrastructure is still catching up. Traditional syndromic surveillance systems (tracking patients with fever, cough, or diarrhea) are already in place but rely on people showing up at hospitals.

Wastewater surveillance changes that equation. It brings data from households, schools, workplaces, and entire communities—even those who never set foot in a clinic. That means potential hot spots can be identified and interventions rolled out before the first wave of hospitalizations.

The surveillance will be carried out through ICMR’s national network of Viral Research and Diagnostic Laboratories, which already tests about 1,500 patient samples a week for respiratory illnesses. Adding wastewater to the mix gives India a more layered, resilient system of outbreak detection.

If successful, the program could eventually scale nationwide and serve as a model for other low- and middle-income countries. Integrating wastewater surveillance with India’s Ayushman Bharat Digital Mission (a massive health data initiative) could turn real-time sewage signals into actionable alerts for policymakers and communities alike.

Wastewater may not be glamorous, but it might just be one of the most powerful public health tools of the 21st century. By expanding its surveillance network to 50 cities, India is not just strengthening its defenses against outbreaks it’s offering the world a glimpse of how proactive, community-level monitoring could rewrite the rules of epidemic preparedness.

wastewater surveillance india

icmr wastewater monitoring

sewage disease tracking

early outbreak detection

antimicrobial resistance india

wastewater epidemiology

public health surveillance

The Indian Council of Medical Research (ICMR) is embarking on one of its most ambitious public health projects yet—expanding wastewater surveillance from five cities to 50 within the next six months. The program will track 10 different viruses, including influenza strains and pathogens responsible for fever, diarrheal illnesses, encephalitis, and respiratory infections.The goal is simple but powerful: to create an early warning system for outbreaks before they overwhelm hospitals. For India, a country with a vast and densely packed population, the ability to detect viral threats at the community level could be transformative. For the rest of the world, the project provides a case study of how wastewater-based epidemiology (WBE) can help governments prepare for and potentially prevent pandemics.What Is Wastewater Surveillance?Wastewater surveillance, also called Wastewater-Based Epidemiology (WBE), is the practice of analyzing sewage for fragments of viruses, bacteria, and other pathogens that people shed when they use toilets, sinks, or showers.An infected person symptomatic or not will excrete viral particles through stool, urine, or even when washing. These particles end up in community sewage. When scientists collect and test these samples, they can detect infection trends in entire populations, sometimes weeks before clinical cases surface in hospitals.Unlike hospital-based testing, which only captures people who seek medical care, wastewater surveillance gives a panoramic view of community health, including those who are asymptomatic, undiagnosed, or reluctant to get tested.Why India Is Betting Big on Sewage Science?Currently, India uses wastewater surveillance to monitor COVID-19 and polio. But with ICMR’s expansion plan, the program will track up to 10 viruses. Among them: avian influenza viruses and pathogens associated with acute encephalitis syndrome, diarrheal outbreaks, and respiratory infections.This move isn’t just about academic curiosity. It’s about preparedness. India, like many other countries, is witnessing a rise in emerging and re-emerging pathogens fueled by rapid urbanization, climate shifts, increased human-animal interaction, and dense living conditions. With its massive population and vulnerable healthcare infrastructure, early detection is not optional, it’s essential.The scaling up from five cities to 50 represents a tenfold leap in capacity, one that could significantly strengthen India’s ability to anticipate outbreaks and allocate resources before a crisis spirals.How Wastewater Surveillance Process Works?The science behind wastewater surveillance follows a clear workflow:Pathogen Shedding – People infected with a virus shed particles into sewage through waste or while washing.Collection – Samples are taken from untreated sewage at pumping stations or before treatment plants.Laboratory Testing – Viral fragments (RNA/DNA) are extracted and tested using advanced molecular methods.Data Analysis – Trends in viral load are mapped, typically providing a snapshot of community infections within 5–7 days.Public Health Action – Authorities can respond with outbreak alerts, vaccination drives, and resource mobilization.In short, wastewater turns into a real-time diagnostic tool—not for individuals, but for entire neighborhoods and cities.Was COVID-19 First Detected Through Wastewater Surveillance?If there’s one proof of concept for WBE, it’s the COVID-19 pandemic. In India, a study from Mumbai showed the SARS-CoV-2 virus was detectable in wastewater up to three weeks before clinical diagnoses surged. In Pune, scientists detected the XBB strain months ahead of physicians reporting the first confirmed cases.Across the world, from Sydney to San Diego, cities leveraged wastewater as an important gauge of viral spread, enabling policymakers to coordinate with greater precision by timing restrictions, calibrating testing, or initiating vaccination campaigns.This forecasting ability is precisely why India's growth is important. Picking up on early warning signs in sewage might be the difference between a localized outbreak and a national crisis.How Does Wastewater Surveillance Addressing More Than Just Viruses?Perhaps the most underestimated use for wastewater monitoring is to monitor antimicrobial resistance (AMR)—an invisible international threat that might render many antibiotics obsolete.India already has an AMR surveillance program in place through a network of 60 hospitals tracking which medicines are effective against which infections.But this only captures patients who make it to hospitals. Wastewater surveillance can reveal resistance patterns at the community level, detecting resistant pathogens carried by people who never seek treatment.Given projections that AMR could kill 10 million people annually worldwide by 2050, this kind of broad, real-world data is critical.How Wastewater Surveillance Can Predict Viral Outbreaks?India’s program is ambitious, but it’s part of a larger global shift. The U.S. Centers for Disease Control and Prevention (CDC) already uses wastewater to monitor COVID-19 and other pathogens. In Australia, Dr. Jiaying Li and her team at the University of Sydney developed wastewater methods to track not only viruses but also “forever chemicals” and illicit drug residues, showing the technique’s versatility.These international examples highlight why public health experts call WBE the “stethoscope of cities.” It listens to what individuals may not yet know about their health and helps leaders act before hospitals get overwhelmed.For India, timing is everything. The country has weathered devastating outbreaks—from the 2009 H1N1 flu to COVID-19’s Delta surge—and its public health infrastructure is still catching up. Traditional syndromic surveillance systems (tracking patients with fever, cough, or diarrhea) are already in place but rely on people showing up at hospitals.Wastewater surveillance changes that equation. It brings data from households, schools, workplaces, and entire communities—even those who never set foot in a clinic. That means potential hot spots can be identified and interventions rolled out before the first wave of hospitalizations.The surveillance will be carried out through ICMR’s national network of Viral Research and Diagnostic Laboratories, which already tests about 1,500 patient samples a week for respiratory illnesses. Adding wastewater to the mix gives India a more layered, resilient system of outbreak detection.If successful, the program could eventually scale nationwide and serve as a model for other low- and middle-income countries. Integrating wastewater surveillance with India’s Ayushman Bharat Digital Mission (a massive health data initiative) could turn real-time sewage signals into actionable alerts for policymakers and communities alike.Wastewater may not be glamorous, but it might just be one of the most powerful public health tools of the 21st century. By expanding its surveillance network to 50 cities, India is not just strengthening its defenses against outbreaks it’s offering the world a glimpse of how proactive, community-level monitoring could rewrite the rules of epidemic preparedness.

wastewater surveillance in india: can sewage help detect viruses before outbreaks?

Ishita Roy

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The U.S. Food and Drug Administration (FDA) has suspended the biologics license for Ixchiq, a live-attenuated <span>chikungunya</span> vaccine, following reports of serious adverse reactions in older adults. The side effects closely mirrored symptoms of chikungunya virus itself, raising concerns about patient safety and the vaccine’s overall clinical benefit.

Chikungunya is a mosquito-borne viral infection that causes high fever, rash, headaches, nausea, fatigue, and severe joint and muscle pain. The illness is notorious for its long-lasting impact, with some patients experiencing disabling joint pain for months or even years.

<h2>Global rise in chikungunya cases</h2>

The FDA decision comes at a time when chikungunya cases are surging worldwide. In recent months, outbreaks have been reported across South America, Asia, and Africa. The World Health Organization (WHO) has noted significant increases in Brazil, Paraguay, and India, with localized outbreaks also being reported in parts of Southeast Asia.

In the United States, sporadic travel-related cases have been documented, though no major outbreak has yet occurred. Concern is growing that climate change and global travel could expand the reach of chikungunya-carrying mosquitoes to new regions.

<h2>U.S. issues travel advisory for China amid outbreaks</h2>

Adding to global health concerns, the U.S. recently issued a travel advisory for Americans visiting China after reports of chikungunya cases in several provinces. Health officials have urged travelers to take preventive measures such as using mosquito repellents, wearing long-sleeved clothing, and staying in well-screened accommodations. The advisory highlights the urgency of preventive strategies as global cases rise.

<strong>Read: <a href="https://www.healthandme.com/health-news/us-weighs-china-travel-warning-as-chikungunya-cases-near-5000-report-article-152393518" data-type="tilCustomLink">US Weighs China Travel Warning As Chikungunya Cases Near 5,000: Report</a></strong>

<h2>Safety issues with Ixchiq vaccine</h2>

Ixchiq, developed by French biotech company Valneva, received accelerated FDA approval in November 2023. It was intended to protect adults aged 18 and older at increased risk of exposure to the virus. However, post-approval monitoring has revealed troubling safety signals.

<h3>According to the FDA’s Vaccine Adverse Event Reporting System (VAERS):</h3>

<ul><li>One confirmed case of encephalitis-related death has been linked to the vaccine.</li><li>More than 20 serious adverse events resembling chikungunya illness have been reported.</li><li>21 hospitalizations and three total deaths have been associated with vaccination.</li></ul>

The FDA’s Center for Biologics Evaluation and Research concluded that Ixchiq’s clinical benefits remain unproven and that its risks outweigh potential advantages for most individuals. Regulators determined that continued use in the U.S. could jeopardize public health.

<strong>Read: <a href="https://www.healthandme.com/health-news/mosquitoes-deployed-to-kill-virus-carrying-mosquito-larvae-how-china-is-using-biological-weapons-to-wage-war-against-chikungunya-article-152416485" data-type="tilCustomLink">Mosquitoes Deployed To Kill Virus-Carrying Mosquito Larvae: How China Is Using Biological Weapons To Wage War Against Chikungunya</a></strong>

<h2>Manufacturer defends vaccine but halts U.S. distribution</h2>

Valneva, the vaccine’s manufacturer, has defended its product, stating that the reported side effects align with known risks identified during clinical trials. The company emphasized that older adults had already been flagged for potential complications in prescribing information.

“As we determine potential next steps, and as the clear threat of chikungunya continues to escalate globally, Valneva remains fully committed to maintaining access to our vaccine as a global health tool for addressing and preventing outbreaks of this devastating illness,” Valneva CEO Thomas Lingelbach said in a statement.

The company has confirmed that while Ixchiq will no longer be shipped or sold in the U.S., it will continue to be made available in other countries where it is licensed. Valneva also reiterated its commitment to accelerating vaccine access in low- and middle-income nations where chikungunya remains endemic.

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The U.S. Food and Drug Administration (FDA) has suspended the biologics license for Ixchiq, a live-attenuated chikungunya vaccine, following reports of serious adverse reactions in older adults. The side effects closely mirrored symptoms of chikungunya virus itself, raising concerns about patient safety and the vaccine’s overall clinical benefit.Chikungunya is a mosquito-borne viral infection that causes high fever, rash, headaches, nausea, fatigue, and severe joint and muscle pain. The illness is notorious for its long-lasting impact, with some patients experiencing disabling joint pain for months or even years.Global rise in chikungunya casesThe FDA decision comes at a time when chikungunya cases are surging worldwide. In recent months, outbreaks have been reported across South America, Asia, and Africa. The World Health Organization (WHO) has noted significant increases in Brazil, Paraguay, and India, with localized outbreaks also being reported in parts of Southeast Asia.In the United States, sporadic travel-related cases have been documented, though no major outbreak has yet occurred. Concern is growing that climate change and global travel could expand the reach of chikungunya-carrying mosquitoes to new regions.U.S. issues travel advisory for China amid outbreaksAdding to global health concerns, the U.S. recently issued a travel advisory for Americans visiting China after reports of chikungunya cases in several provinces. Health officials have urged travelers to take preventive measures such as using mosquito repellents, wearing long-sleeved clothing, and staying in well-screened accommodations. The advisory highlights the urgency of preventive strategies as global cases rise.Read: US Weighs China Travel Warning As Chikungunya Cases Near 5,000: ReportSafety issues with Ixchiq vaccineIxchiq, developed by French biotech company Valneva, received accelerated FDA approval in November 2023. It was intended to protect adults aged 18 and older at increased risk of exposure to the virus. However, post-approval monitoring has revealed troubling safety signals.According to the FDA’s Vaccine Adverse Event Reporting System (VAERS):One confirmed case of encephalitis-related death has been linked to the vaccine.More than 20 serious adverse events resembling chikungunya illness have been reported.21 hospitalizations and three total deaths have been associated with vaccination.The FDA’s Center for Biologics Evaluation and Research concluded that Ixchiq’s clinical benefits remain unproven and that its risks outweigh potential advantages for most individuals. Regulators determined that continued use in the U.S. could jeopardize public health.Read: Mosquitoes Deployed To Kill Virus-Carrying Mosquito Larvae: How China Is Using Biological Weapons To Wage War Against ChikungunyaManufacturer defends vaccine but halts U.S. distributionValneva, the vaccine’s manufacturer, has defended its product, stating that the reported side effects align with known risks identified during clinical trials. The company emphasized that older adults had already been flagged for potential complications in prescribing information.“As we determine potential next steps, and as the clear threat of chikungunya continues to escalate globally, Valneva remains fully committed to maintaining access to our vaccine as a global health tool for addressing and preventing outbreaks of this devastating illness,” Valneva CEO Thomas Lingelbach said in a statement.The company has confirmed that while Ixchiq will no longer be shipped or sold in the U.S., it will continue to be made available in other countries where it is licensed. Valneva also reiterated its commitment to accelerating vaccine access in low- and middle-income nations where chikungunya remains endemic.

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