FDA Approves Its First Rapid-Acting Insulin Product For People With Diabetes

Updated Feb 20, 2025 | 02:20 PM IST

SummaryDiabetes is a major issue for many people all over the world. Statistics show that more than half of the people who have diabetes do not even know it! And even for the ones who know, medicine is a big hassle as there were no quick acting ones they could use. But a recent approval from FDA has changed that fact!
(Credit-Canva)

(Credit-Canva)

Diabetes has become a silent epidemic in many ways. According to the International Diabetes Federation, about 10.5% of the adult population has diabetes and a lot of them remain unaware that they are living with the condition. It also predicts that by 2045 every 1 adult in a group of 8 will have diabetes, which means approximately 783 million people will have it, which is an increase of 46%. In these statistics, more than 90% of the people are living with type 2 diabetes.

While there have been a lot of medical improvements when it comes to treatment options for diabetes, a new drug has been approved which is not only fast and rapid acting, but it is also the first of its kind to be approved. The U.S. Food and Drug Administration (FDA) has given the green light to Merilog, a new medicine that helps people with diabetes control their blood sugar.

This medicine is a biosimilar, which means it's very similar to another approved medicine called Novolog. Merilog is for both adults and kids who have diabetes. It's the first quick-acting insulin of its kind that the FDA has approved.

The science behind this is simple, when you eat, your blood sugar goes up, and Merilog helps bring it back down quickly. It comes in two forms, a pen that you use once and then throw away, and a bottle you can use many times. This gives people options for how they want to take their insulin.

What Is The Significance Of This?

Merilog is the third insulin biosimilar that the FDA has approved. Before this, they approved two long-acting insulins. Biosimilars are important because they can help more people get the medicines they need. The FDA wants to make it easier for biosimilars to be approved so that there are more choices for patients. They hope this will make medicines like insulin more affordable. A biosimilar is like a generic version of a complex medicine. It works just as well as the original. The FDA has approved many biosimilars for different health problems. They are working hard to make sure people can get safe and good medicines at a lower cost.

About 8.4 million people in the U.S. use insulin to manage their diabetes. It's important to have different kinds of insulin, like quick-acting and long-acting, to control blood sugar throughout the day. The FDA wants to make sure people have access to these medicines. Having more options can help people get the insulin they need to live healthy lives. Biosimilars are one way to make that happen.

How To Use Merilog And What Are Its Safety Measures?

You take Merilog by injecting it under your skin, usually in your stomach, thighs, or upper arms. It's important to take it a few minutes before you eat. Your doctor will tell you how much to take, as everyone's needs are different. Like any medicine, Merilog can have side effects. Sometimes, people get low blood sugar, which is called hypoglycemia. Some people can have bad allergic reactions or low potassium in their blood. Common side effects can include redness or swelling where you inject it, itching, or weight gain. It's important to talk to your doctor about any side effects you might have.

Sources

https://idf.org/about-diabetes/diabetes-facts-figures/

https://www.fda.gov/news-events/press-announcements/fda-approves-first-rapid-acting-insulin-biosimilar-product-treatment-diabetes

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Mounjaro Price Increase: Eli Lilly to Hike UK Cost of Weight-Loss Drug by 170%

Updated Aug 14, 2025 | 08:48 PM IST

SummaryEli Lilly will raise UK prices of its weight-loss and diabetes drug Mounjaro by up to 170 per cent from September, targeting private patients while keeping NHS costs unchanged, citing the need to match prices with other developed countries and ensure supply.
Mounjaro’s UK Price Hike

Credits: Canva

Eli Lilly will significantly increase the UK price of its weight-loss and diabetes drug Mounjaro from September. The company says the rise is intended to align UK costs with those in other developed nations and address pricing disparities. The US pharma giant has announced it will raise the price of its popular drug, also prescribed for type 2 diabetes, by as much as 170 per cent.

According to Lilly, the hike will bring UK prices more in line with other wealthy nations in Europe and beyond.

The NHS Gets a Pass… For Now

Know that the NHS won't be hit by this increase. The higher prices are aimed squarely at private patients and providers, who can negotiate hush-hush discounts behind closed clinic doors. Reports suggest that the highest monthly dose will leap from £122 to £330, while lower doses will see bumps between 45 and 138 per cent.

If you have been relying on Mounjaro as your secret weapon against stubborn kilos, this could be the financial equivalent of your personal trainer suddenly charging three times more for the same number of push-ups.

Life Without the Jab

Of course, for some, the looming price jump is more than a budget annoyance; it is a motivation crisis. But you do not actually need to stick a needle in your thigh to get “Mounjaro-like” weight loss.

Here is how to hack your habits so your body thinks it is on the metabolism-boosting fast track, without any pharmaceutical intervention.

Eat Like You Mean It

Most of what Mounjaro does can be replicated through daily habits. Step one? Food. High-protein, high-fibre, healthy-fat meals keep you full longer, suppress sugar cravings, and make overeating less tempting. Avoid large meals, sugar, and processed food. And slow, mindful eating gives your brain time to catch up with your stomach.

Even your water bottle can become a weight-loss tool. A lot of what people think is hunger is actually dehydration. Electrolyte-rich water—with sodium, potassium, and magnesium—can curb cravings and keep energy levels stable.

Pick Up Heavy Things

While pounding the treadmill has its place, strength training is the real game-changer for long-term fat loss. Muscle tissue burns more calories at rest than fat. Plus, medications like Mounjaro and Ozempic can cause muscle loss if you are not lifting weights, leading to a slimmer but softer physique. Resistance training preserves muscle and shapes the body more effectively.

Sleep, Stress, and Staying the Course

Before you dismiss rest as “lazy time”, remember it is a weight-loss essential. Poor sleep and chronic stress raise cortisol and blood sugar, making fat loss harder. Consistency is king. A regular schedule for eating, exercising, and resting does more for your metabolism than any magic shot.

Surgery, Skincare, and Staying Realistic

Medication-induced weight loss can come with aesthetic and medical trade-offs. Rapid weight loss often means loose, sagging skin, and there are reports linking GLP-1 drugs to inflammatory issues and even certain cancers.

There are alternatives that avoid the “melted candle” effect of sudden slimming. Swallowable balloons reduce stomach capacity gradually, minimising skin laxity. For sculpting, there is 360 body contouring or liposuction with skin-tightening tech.

If you are needle-shy but still chasing definition, go for cryotherapy or lipolytic injections for stubborn fat. They are great for shape refinement, not full-body weight loss.

When the Price Tag Becomes the Push

For many, the new Mounjaro pricing might be the gentle nudge needed to ditch the drug and rediscover the old-school ways of getting lean: mindful eating, muscle-building, and sleep that actually lets your body recover.

The reality is, drugs like Mounjaro can be revolutionary for people with serious metabolic issues, but for those using it as a shortcut, the financial bite may soon feel sharper than the injection. Whether you keep your jab or kick it, remember that sustainable weight loss has always been less about the price tag on your medicine cabinet and more about the habits that shape your daily life.

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XFG ‘Stratus’ COVID Now Dominant in US: States With Highest Cases and How to Spot Unique Symptoms

Updated Aug 14, 2025 | 06:20 PM IST

SummaryThe XFG “Stratus” COVID-19 variant, now the third most common in the US, is surging in 12 states with high positivity rates. Known for symptoms like “razor blade throat”, it spreads quickly but remains covered by current vaccines.
XFG ‘Stratus’ COVID Now Dominant in US

Credits: Canva

The XFG “Stratus” COVID-19 variant is officially strutting into the pandemic spotlight. It is new, it is bold, and according to the latest data from the Centres for Disease Control and Prevention (CDC), it is now the third most common variant in the US. But it is popping up in certain states more than others, and the way it announces its arrival could be by making your throat feel like you have swallowed a box of sandpaper.

While the national Covid-19 test positivity rate sits in the 5–9.9 per cent range, a dozen states are seeing significantly higher numbers.

According to CDC data, the states with the highest positivity rates are:

  • New Mexico (12%)
  • Texas (12%)
  • Oklahoma (12%)
  • Arkansas (12%)
  • Louisiana (12%)
  • Nevada (11.3%)
  • Arizona (11.3%)
  • California (11.3%)
  • Alaska (11.1%)
  • Washington (11.1%)
  • Oregon (11.1%)
  • Idaho (11.1%)

These states are not just reporting higher numbers but are also providing ideal conditions for Stratus to spread. With case trends officially “growing” according to the CDC, it is a situation that demands close attention.

Stratus is a variant under monitoring by the World Health Organisation (WHO). First detected in January, XFG Stratus now accounts for about 14 per cent of Covid cases in the US.

While theW says the health risk from Stratus remains low at a global level, this variant is still on a growth spurt, outpacing other circulating forms of the virus, including its sibling, the “Nimbus” NB.1.8.1 variant. The concerning bit is that the WHO says Stratus could be more adept at sidestepping immune defences. The reassuring bit is that the current vaccines are expected to continue protecting against symptomatic and severe disease caused by Stratus.

Spotting Unique Stratus Symptoms

The tricky thing about Stratus is that it is not trying to reinvent the Covid symptom wheel. According to experts, its symptoms look suspiciously similar to other recent Omicron descendants. But there is one possible stand-out, a sensation some patients are calling “razor blade throat”.

Here’s the full checklist:

  • Sore throat (sometimes severe)
  • Cough
  • Congestion or runny nose
  • Fever or chills
  • Shortness of breath
  • Loss of taste or smell
  • Fatigue
  • Headache
  • Muscle aches
  • Nausea, vomiting or diarrhoea

The “razor blade throat” description might sound too much, but anyone who has had that burning, scratchy pain knows it is no joke. Hoarseness has also been reported more often lately. Still, a sore throat has been a hallmark Covid symptom since the early days of the pandemic; Stratus just seems to be leaning into it.

Why the Positivity Spike Matters

Higher positivity rates do not just mean more people are testing positive; they can also signal under-testing. If more than 10 per cent of people tested are infected, it suggests many cases are flying under the radar, which means more opportunities for the virus to spread unchecked. That is especially risky when you have a variant with a knack for growing its share of cases quickly, like Stratus.

The fact that 12 states are sitting above the 11 per cent mark means public health teams will be watching these regions closely in the coming weeks. In the meantime, everyday precautions like masking in crowded places, testing if symptomatic, and staying up to date with vaccines remain the best tools in the toolbox.

Stratus vs. Nimbus

While Stratus is currently the one hogging headlines, it is not alone. The “Nimbus” NB.1.8.1 variant is still in the mix, though it is being outpaced by Stratus globally.

For now, Stratus is the one to watch and not because it is the most dangerous, but because it is the fastest climber.

Final Forecast

The XFG Stratus variant is not changing anything, but it is a reminder that the virus is still evolving and still finding ways to make itself known. Got a sudden sore throat that feels like sandpaper? Do not brush it off. Stratus may not be a storm you can see on a weather map, but it is definitely in the air.

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UK Health Chiefs Warn of Rising Cases of Deadly Chikungunya Virus That Can Cause Body to ‘Fold In on Itself’

Updated Aug 14, 2025 | 01:02 PM IST

SummaryUK health officials have reported record chikungunya cases and the first oropouche virus infections, both linked to overseas travel. Spread by mosquitoes and midges, these viruses cause severe symptoms, with prevention through repellents, protective clothing, and vaccination recommended for travellers.
Credits: Canva

Credits: Canva

Health authorities in the UK have reported a significant rise in chikungunya cases, a mosquito-borne disease known for causing severe joint pain that can leave sufferers hunched over. Between January and June 2025, there were 73 confirmed cases in England, Wales, and Northern Ireland, more than double the 27 recorded during the same period in 2024. The UK Health Security Agency (UKHSA) says this is the highest number ever recorded, with nearly all linked to overseas travel.

What is Chikungunya?

Spread by the bite of infected Aedes mosquitoes, particularly the Aedes aegypti and Aedes albopictus species, chikungunya is not usually deadly but can be devastating for the very young, the elderly, or those with underlying health conditions.

Typical symptoms include:

  • Excruciating joint pain that can leave sufferers bent over in agony
  • High fever and headaches
  • Muscle aches and swelling in the joints (especially hands and feet)
  • Nausea, fatigue, and a rash that’s red, bumpy, and decidedly not Instagrammable

In severe cases, the arthritis-like pain can linger for months or even years, turning every movement into a reminder that mosquitoes are not just a mild holiday nuisance.

The majority of UK cases this year were linked to travel to Sri Lanka, India, and Mauritius. All were reported in England, with London taking the dubious honour of having the most cases. However, the two mosquito species that spread the virus are not established in the UK, so there is no risk of it transmitting locally.

UK logs first cases of oropouche virus

As if one virus was not enough, the UK has also logged its first cases of the oropouche virus, also dubbed ‘sloth fever’. This one circulates in the wild between primates, sloths, and birds before occasionally hopping over to humans via midges or mosquitoes.

Found primarily in the Amazon basin, oropouche has recently started wandering further across the Americas. All the UK cases were linked to travel from Brazil, so unless your staycation involves tree-dwelling mammals and tropical insects, you are safe for now.

The Global Bug Crawl

Chikungunya is typically found in Africa and southern Asia, but 2025 has seen it pop up in unexpected places. Outbreaks have been reported in China, the Indian Ocean islands of Reunion, Mayotte and Mauritius, and across the Americas. In southern China, more than 7,000 people have been infected since June, prompting COVID-style lockdowns in Foshan and at least a dozen other cities in Guangdong province. Hong Kong and Taiwan have also reported cases.

Health officials are urging travellers to take bite prevention seriously.

How to safeguard against mosquito bites

According to the US Centres for Disease Control and Prevention (CDC), your best defence is to stop mosquitoes from making contact in the first place.

Top tips include:

  • Use Environmental Protection Agency (EPA)-registered insect repellent
  • Wear long-sleeved shirts and trousers (mosquitoes can’t bite what they can’t reach)
  • Treat clothing and gear with 0.5% permethrin for extra armour
  • Choose accommodation with air conditioning or window screens
  • If sleeping outdoors, use a mosquito net unless you enjoy sharing your bed with the local insect population

Vaccination

In addition to covering up and dousing yourself in repellent, some travellers may be advised to get the chikungunya vaccine before heading to certain destinations. Your healthcare provider can help you decide if this applies to your travel plans.

Why the Surge Now?

Several factors could be behind the sharp rise in cases. Increased international travel post-pandemic, changing weather patterns favouring mosquito breeding, and outbreaks in popular holiday destinations have created a perfect storm. Mosquitoes thrive in warm, wet conditions, and with climate change extending those conditions into more regions, these viruses are no longer staying politely within their old borders.

Chikungunya virus can turn a dream getaway into a painful endurance test, and once contracted, it is all about managing symptoms; there is no cure. The same goes for oropouche: prevention is your best friend. In the world of tropical diseases, an ounce of repellent really is worth a pound of cure.

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