Health and Me

Tanya Dutt

India Bans Cough Syrups For Children Under 4 Due To Safety Concerns

In a breakthrough step towards safeguarding infant and toddler health, the Government of India has formally prohibited the use of some commonly found over-the-counter (OTC) cough and cold medicines in children below the age of four. This policy move, as notified by the Union Ministry of Health and Family Welfare through a gazette notification, prohibits the use of a fixed-dose combination (FDC) of <span>Chlorpheniramine Maleate</span> and Phenylephrine Hydrochloride—two ingredients found in many pediatric cough syrups.

The decision follows an increasingly vocal global health chorus of alarm at the safety of these products among very young children, India now being among the latest to make strong regulatory moves.

The fixed-dose combination in question has been used to alleviate symptoms of the common cold and allergic rhinitis for a long time. Nonetheless, after reviewing the same, a Subject Expert Committee (SEC) constituted by the Central Government with suggestions from the Drugs Technical Advisory Board (DTAB) opined that this combination is likely to produce risks for children under four years of age—risks overweighing possible benefits.

As per the Health Ministry's statement, "the use of the fixed-dose combination is likely to pose risk to children under the age of four, and safer options to the aforementioned drug are in place."

The government used Section 26A of the Drugs and Cosmetics Act, 1940, to limit the production, sale, and supply of these formulations for pediatric administration in India.

The now-restricted combination consists of two commonly prescribed ingredients:

Chlorpheniramine Maleate: An antihistamine that operates by inhibiting histamine receptors in the body, relieving symptoms such as sneezing, watery eyes, and runny nose.

<span>Phenylephrine Hydrochloride</span>: A decongestant that constricts blood vessels in the nostrils to narrow them and improve breathing.

Collectively, they've had different brand names and are household essentials in all Indian homes for treating cold as well as allergy conditions. The preparations, though usually safe for adults and older kids, are found to be potentially unsafe for toddlers.

<h2>Why the Risk is Greater for Toddler?</h2>

Infants under the age of four are at greater risk for side effects due to their immature organ systems and lower body weight. Even normal doses can produce exaggerated physiological effects.

Drowsiness, restlessness, dizziness, or even paradoxical excitation (hyperactivity rather than sedation) can result from chlorpheniramine and be particularly hazardous in infants.

Phenylephrine is a stimulant that can raise blood pressure, induce palpitations, and produce headaches. Its vasoconstricting effect, while useful in nasal decongestion, can impose excessive strain on a child's cardiovascular system.

All these compounds, when used in combination, have an intricate pharmacological profile that can do unintended damage if taken without tight medical surveillance.

Apart from prohibiting the mixture for children under four, the government has asked manufacturers to put a clear warning label on all packaging, inserts, and advertising materials.

<em>The warning that must be used is: This fixed-dose combination shall not be used in children below four years of age.</em>

This choice isn't just a one based on regulation but rather an educational choice as well, trying to notify parents, caregivers, and healthcare workers of the danger of self-medicating infants and toddlers outside of a physician's recommendation.

Yes, the prohibition is the result of the availability of safer, more targeted alternatives. Pediatricians frequently suggest utilizing saline nasal drops, humidifiers, or warm liquids to relieve cold symptoms in children. In more severe instances, medications targeting specific symptoms are prescribed under close dosage control.

It's crucial to keep in mind that a majority of colds are viral infections that naturally go away by themselves. Medicating symptoms with aggressive medication, particularly in kids under four years old, more often than not causes more damage than good.

<ul><li>Talk to pediatricians before administering any OTC cold or allergy medication to kids.</li><li>Don't use leftover or adult-strength formulas, even in reduced amounts.</li><li>Read labels before buying drugs and look for the new government-required warning.</li><li>Watch for side effects if the drug has already been taken and obtain instant medical care for any side effects.</li></ul>

India's regulatory action reflects worldwide thinking. Other nations such as the U.S., Canada, and the U.K. had earlier issued guidelines or warnings concerning the use of OTC cough and cold medicines among young children.

In the United States, the FDA recommends against administration of cold drugs to children less than two and cautions against even those two to six. Likewise, the American Academy of Pediatrics (AAP) has cautioned against the use of OTC cough and cold medicines in kids less than four years old as a matter of long-standing concern regarding insufficient benefit and possible risks.

India's move is consistent with this evidence-based strategy, reinforcing the global push toward child-specific formulations, careful monitoring, and public health education.

The prohibition on children under four using cough syrup combinations is an important step towards more rational and safer use of drugs in pediatric care. As greater awareness emerges regarding the subtleties of treating younger children, particularly in non-clinical environments, policy like this one serves to protect the most vulnerable groups.

For parents, the message is simple: drugs that are effective for adults or older kids are not necessarily safe for toddlers. If it's questionable, always call a physician.

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In a breakthrough step towards safeguarding infant and toddler health, the Government of India has formally prohibited the use of some commonly found over-the-counter (OTC) cough and cold medicines in children below the age of four. This policy move, as notified by the Union Ministry of Health and Family Welfare through a gazette notification, prohibits the use of a fixed-dose combination (FDC) of Chlorpheniramine Maleate and Phenylephrine Hydrochloride—two ingredients found in many pediatric cough syrups.The decision follows an increasingly vocal global health chorus of alarm at the safety of these products among very young children, India now being among the latest to make strong regulatory moves.The fixed-dose combination in question has been used to alleviate symptoms of the common cold and allergic rhinitis for a long time. Nonetheless, after reviewing the same, a Subject Expert Committee (SEC) constituted by the Central Government with suggestions from the Drugs Technical Advisory Board (DTAB) opined that this combination is likely to produce risks for children under four years of age—risks overweighing possible benefits.As per the Health Ministry's statement, "the use of the fixed-dose combination is likely to pose risk to children under the age of four, and safer options to the aforementioned drug are in place."The government used Section 26A of the Drugs and Cosmetics Act, 1940, to limit the production, sale, and supply of these formulations for pediatric administration in India.What Are These Drugs?The now-restricted combination consists of two commonly prescribed ingredients:Chlorpheniramine Maleate: An antihistamine that operates by inhibiting histamine receptors in the body, relieving symptoms such as sneezing, watery eyes, and runny nose.Phenylephrine Hydrochloride: A decongestant that constricts blood vessels in the nostrils to narrow them and improve breathing.Collectively, they've had different brand names and are household essentials in all Indian homes for treating cold as well as allergy conditions. The preparations, though usually safe for adults and older kids, are found to be potentially unsafe for toddlers.Why the Risk is Greater for Toddler?Infants under the age of four are at greater risk for side effects due to their immature organ systems and lower body weight. Even normal doses can produce exaggerated physiological effects.Drowsiness, restlessness, dizziness, or even paradoxical excitation (hyperactivity rather than sedation) can result from chlorpheniramine and be particularly hazardous in infants.Phenylephrine is a stimulant that can raise blood pressure, induce palpitations, and produce headaches. Its vasoconstricting effect, while useful in nasal decongestion, can impose excessive strain on a child's cardiovascular system.All these compounds, when used in combination, have an intricate pharmacological profile that can do unintended damage if taken without tight medical surveillance.Apart from prohibiting the mixture for children under four, the government has asked manufacturers to put a clear warning label on all packaging, inserts, and advertising materials.The warning that must be used is: This fixed-dose combination shall not be used in children below four years of age.This choice isn't just a one based on regulation but rather an educational choice as well, trying to notify parents, caregivers, and healthcare workers of the danger of self-medicating infants and toddlers outside of a physician's recommendation.Are There Safer Alternatives?Yes, the prohibition is the result of the availability of safer, more targeted alternatives. Pediatricians frequently suggest utilizing saline nasal drops, humidifiers, or warm liquids to relieve cold symptoms in children. In more severe instances, medications targeting specific symptoms are prescribed under close dosage control.It's crucial to keep in mind that a majority of colds are viral infections that naturally go away by themselves. Medicating symptoms with aggressive medication, particularly in kids under four years old, more often than not causes more damage than good.What Should Parents Do Now?Talk to pediatricians before administering any OTC cold or allergy medication to kids.Don't use leftover or adult-strength formulas, even in reduced amounts.Read labels before buying drugs and look for the new government-required warning.Watch for side effects if the drug has already been taken and obtain instant medical care for any side effects.India's regulatory action reflects worldwide thinking. Other nations such as the U.S., Canada, and the U.K. had earlier issued guidelines or warnings concerning the use of OTC cough and cold medicines among young children.In the United States, the FDA recommends against administration of cold drugs to children less than two and cautions against even those two to six. Likewise, the American Academy of Pediatrics (AAP) has cautioned against the use of OTC cough and cold medicines in kids less than four years old as a matter of long-standing concern regarding insufficient benefit and possible risks.India's move is consistent with this evidence-based strategy, reinforcing the global push toward child-specific formulations, careful monitoring, and public health education.The prohibition on children under four using cough syrup combinations is an important step towards more rational and safer use of drugs in pediatric care. As greater awareness emerges regarding the subtleties of treating younger children, particularly in non-clinical environments, policy like this one serves to protect the most vulnerable groups.For parents, the message is simple: drugs that are effective for adults or older kids are not necessarily safe for toddlers. If it's questionable, always call a physician.

india bans cough syrups for children under 4 due to safety concerns

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Gas Station Heroin: What Is The Dangerous 'Cognitive Supplement' Experts Are Warning About?

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US health officials are raising serious concerns about 'Gas Station Heroin', a substance called <span>tianeptine</span>. This has opioid-like-effects and the availability and accessibility is only increasing. 

It is also sold as over-the-counter supplements at gas stations, smoke shops, and convenience store. The drug is also marketed as Zaza, Tianaa, Pegasus, and TD Red.

Though used as an antidepressant in some other countries, tianeptine is not approved for medical use in the United States. Experts warn that its effects can mimic those of opioids, including addiction and withdrawal symptoms, even though it is not officially classified as one.

A 2023 study published in journal Pain and Therapy, notes: "Tianeptine is an antidepressant drug approved for the treatment of major depressive disorder in countries other than the US. It is classified as an atypical tricyclic antidepressant and has shown potential benefits in addressing anxiety and irritable bowel disease. However, it is important to note that tianeptine is not approved for any use by the United States Federal Drug Administration (FDA). Despite its lack of approval by the FDA, tianeptine has been distributed online and at small retail locations."

The term “gas station drugs” refers to a wide range of substances typically available for purchase from gas stations, corner stores, bodegas, mini marts, smoke shops, and the Internet. These substances may be produced commercially by drug manufacturers or in clandestine laboratories to mimic the effects of more well-known illicit/controlled substances such as marijuana, cocaine, opioids, etc.

The study also notes that misuse of tianeptine can lead to euphoric, opioid-like highs with the potential for chronic users to develop dependence and tolerance. Overdose and use in suicide attempts have also been documented. 

Its popularity stems from its ability to bind to the same brain receptors as opioids, which can create feelings of euphoria, calmness, and even pain relief. “It’s kind of this grey area of consumer products, or supplements, where the contents are not regulated or tested the way they would be with a medication,” explained Dr. Diane Calello of the New Jersey Poison Information and Education System. “You never quite know what’s in that bottle.”

<h4>FDA Warns Against Its Easy Accessibility </h4>

In response to rising reports of adverse effects, the FDA issued a formal warning last month, calling tianeptine "a dangerous and growing health trend." The agency urged retailers to stop selling these products and asked consumers to avoid purchasing or using them altogether.

Poison control centers have seen a sharp rise in tianeptine-related incidents. The FDA noted that many of these cases involve young people, and the symptoms often require emergency medical attention. Reported side effects include seizures, low blood pressure, rapid heartbeat, and mental distress. In a review of 20 recent cases, more than half of the patients had to be admitted to intensive care units.

The state of Alabama serves as a stark example of the risks associated with tianeptine. Between 2018 and 2021, poison control calls related to the drug spiked by over 1,400%. However, after the state imposed strict regulations and bans, the number of such incidents saw a notable decline. This indicates that legal restrictions can play a significant role in curbing misuse.

Health professionals are urging federal and state authorities to take faster and stronger action before tianeptine use becomes a full-blown public health crisis. Some compare the current trajectory of the drug to the early days of the opioid epidemic, which caught the country off guard and led to long-term consequences.

gas station heroin drug

tianeptine

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us health news

us news

gas station heroine use in US

US health officials are raising serious concerns about 'Gas Station Heroin', a substance called tianeptine. This has opioid-like-effects and the availability and accessibility is only increasing. It is also sold as over-the-counter supplements at gas stations, smoke shops, and convenience store. The drug is also marketed as Zaza, Tianaa, Pegasus, and TD Red.Though used as an antidepressant in some other countries, tianeptine is not approved for medical use in the United States. Experts warn that its effects can mimic those of opioids, including addiction and withdrawal symptoms, even though it is not officially classified as one.What Is Tianeptine?A 2023 study published in journal Pain and Therapy, notes: "Tianeptine is an antidepressant drug approved for the treatment of major depressive disorder in countries other than the US. It is classified as an atypical tricyclic antidepressant and has shown potential benefits in addressing anxiety and irritable bowel disease. However, it is important to note that tianeptine is not approved for any use by the United States Federal Drug Administration (FDA). Despite its lack of approval by the FDA, tianeptine has been distributed online and at small retail locations."The term “gas station drugs” refers to a wide range of substances typically available for purchase from gas stations, corner stores, bodegas, mini marts, smoke shops, and the Internet. These substances may be produced commercially by drug manufacturers or in clandestine laboratories to mimic the effects of more well-known illicit/controlled substances such as marijuana, cocaine, opioids, etc.The study also notes that misuse of tianeptine can lead to euphoric, opioid-like highs with the potential for chronic users to develop dependence and tolerance. Overdose and use in suicide attempts have also been documented. Its popularity stems from its ability to bind to the same brain receptors as opioids, which can create feelings of euphoria, calmness, and even pain relief. “It’s kind of this grey area of consumer products, or supplements, where the contents are not regulated or tested the way they would be with a medication,” explained Dr. Diane Calello of the New Jersey Poison Information and Education System. “You never quite know what’s in that bottle.”FDA Warns Against Its Easy Accessibility In response to rising reports of adverse effects, the FDA issued a formal warning last month, calling tianeptine "a dangerous and growing health trend." The agency urged retailers to stop selling these products and asked consumers to avoid purchasing or using them altogether.Poison control centers have seen a sharp rise in tianeptine-related incidents. The FDA noted that many of these cases involve young people, and the symptoms often require emergency medical attention. Reported side effects include seizures, low blood pressure, rapid heartbeat, and mental distress. In a review of 20 recent cases, more than half of the patients had to be admitted to intensive care units.The Alabama Case StudyThe state of Alabama serves as a stark example of the risks associated with tianeptine. Between 2018 and 2021, poison control calls related to the drug spiked by over 1,400%. However, after the state imposed strict regulations and bans, the number of such incidents saw a notable decline. This indicates that legal restrictions can play a significant role in curbing misuse.Health professionals are urging federal and state authorities to take faster and stronger action before tianeptine use becomes a full-blown public health crisis. Some compare the current trajectory of the drug to the early days of the opioid epidemic, which caught the country off guard and led to long-term consequences.

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A dangerous airborne fungus that has the potential to rot human tissue from the inside is spreading at a considerably increasing rate across the United States. It has prompted concerns among the medical professionals and public health authorities. <span>Aspergillus fumigatus</span>. This is said to be the culprit behind this surge and poses a risk to especially those whose immune system had been compromised. The cases are becoming harder to treat due to widespread drug resistance and climate-linked proliferation. 

The World Health Organization (WHO) has classified Aspergillus fumigatus as a “critical priority” due to its high mortality rate and growing resistance to existing treatments.

It is called a silent invader for a reason. Once you inhale, the fungus can cause aspergillosis. This is a serious lung infection. The spores are microscopic, which mean hat people can breathe them in unknowingly. For patients who are already vulnerable medically, for instance, those battling cancer, asthma, HIV or recovering from organ transplants, the infection can lead to chronic lung disease, systemic organ failure, or even death. If invasive, it can also spread to your brain, hear, and kidneys.

Despite its potentially fatal consequences, aspergillosis is not classified as a reportable disease in the United States. This means infections are not systematically tracked, leaving health officials with limited data and making it harder to trace or contain outbreaks.

Between 2000 to 2013, hospitalizations have increased in the case of invasive aspergillosis in the US. The rate is reported by a 3% increased, annually. In 2014, the infection led to 15,000 hospital stays, with a cost up to $1.2 billion. 

As the US News notes, postmortem examinations in intensive care units suggest that aspergillosis is among the top four infections most likely to be fatal.

While about 400,000 Americans may be living with chronic pulmonary aspergillosis — the long-term form of the disease — invasive cases, though less frequent, are significantly deadlier. Survival rates drop sharply: just 59% of organ transplant patients and only 25% of stem cell transplant patients live beyond a year after infection.

The fungus thrives in hot, damp, and humid environment. They can also endure up to 120 degree Fahrenheit. This is especially true in compost or agricultural waste. States like Florida, Texas, Georgia, Louisiana, and California — with their humid climates and farming activity — are seeing some of the highest exposure levels. Cities such as New York, Houston, and Los Angeles are also at risk due to overcrowding, aging buildings, and limited ventilation.

According to a University of Manchester study, if fossil fuel use continues at current levels, Aspergillus fumigatus could expand its range by over 75% by 2100 — putting millions more at risk across the southern US.

What is making it even more difficult to control is the increasing drug resistance. Azole drugs — commonly used to treat human fungal infections — are also applied to protect crops. This dual-use, experts say, may be fueling cross-environmental resistance, with drug-resistant spores jumping from soil to humans.

A study published in Applied and Environmental Microbiology found resistant fungal strains in agricultural soil across at least seven US states. Some strains are resistant to multiple standard antifungals, making treatment increasingly difficult.

WHO has also urged pharmaceutical companies to invest in new antifungals, including children in drug trials, and enhance diagnostic and treatment protocols globally.

As of now, doctors recommend to avoid contact with soil, mold, and gardening. It is important to wear protective masks when in dusty areas, and ensure good air filtration at home. 

Aspergillus fumigatus

us health

fungus spreading in US

A dangerous airborne fungus that has the potential to rot human tissue from the inside is spreading at a considerably increasing rate across the United States. It has prompted concerns among the medical professionals and public health authorities. Aspergillus fumigatus. This is said to be the culprit behind this surge and poses a risk to especially those whose immune system had been compromised. The cases are becoming harder to treat due to widespread drug resistance and climate-linked proliferation. The World Health Organization (WHO) has classified Aspergillus fumigatus as a “critical priority” due to its high mortality rate and growing resistance to existing treatments.Silent InvaderIt is called a silent invader for a reason. Once you inhale, the fungus can cause aspergillosis. This is a serious lung infection. The spores are microscopic, which mean hat people can breathe them in unknowingly. For patients who are already vulnerable medically, for instance, those battling cancer, asthma, HIV or recovering from organ transplants, the infection can lead to chronic lung disease, systemic organ failure, or even death. If invasive, it can also spread to your brain, hear, and kidneys.Despite its potentially fatal consequences, aspergillosis is not classified as a reportable disease in the United States. This means infections are not systematically tracked, leaving health officials with limited data and making it harder to trace or contain outbreaks.Infections On The RiseBetween 2000 to 2013, hospitalizations have increased in the case of invasive aspergillosis in the US. The rate is reported by a 3% increased, annually. In 2014, the infection led to 15,000 hospital stays, with a cost up to $1.2 billion. As the US News notes, postmortem examinations in intensive care units suggest that aspergillosis is among the top four infections most likely to be fatal.While about 400,000 Americans may be living with chronic pulmonary aspergillosis — the long-term form of the disease — invasive cases, though less frequent, are significantly deadlier. Survival rates drop sharply: just 59% of organ transplant patients and only 25% of stem cell transplant patients live beyond a year after infection.What Is Causing Its Spread?The fungus thrives in hot, damp, and humid environment. They can also endure up to 120 degree Fahrenheit. This is especially true in compost or agricultural waste. States like Florida, Texas, Georgia, Louisiana, and California — with their humid climates and farming activity — are seeing some of the highest exposure levels. Cities such as New York, Houston, and Los Angeles are also at risk due to overcrowding, aging buildings, and limited ventilation.According to a University of Manchester study, if fossil fuel use continues at current levels, Aspergillus fumigatus could expand its range by over 75% by 2100 — putting millions more at risk across the southern US.What is making it even more difficult to control is the increasing drug resistance. Azole drugs — commonly used to treat human fungal infections — are also applied to protect crops. This dual-use, experts say, may be fueling cross-environmental resistance, with drug-resistant spores jumping from soil to humans.A study published in Applied and Environmental Microbiology found resistant fungal strains in agricultural soil across at least seven US states. Some strains are resistant to multiple standard antifungals, making treatment increasingly difficult.WHO has also urged pharmaceutical companies to invest in new antifungals, including children in drug trials, and enhance diagnostic and treatment protocols globally.Preventive MeasuresAs of now, doctors recommend to avoid contact with soil, mold, and gardening. It is important to wear protective masks when in dusty areas, and ensure good air filtration at home. 

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As the U.S. gears up for the peak summer travel season, a new COVID-19 variant known as NB.1.8.1—or informally, "Nimbus" has rapidly taken center stage in the ongoing pandemic landscape. First identified through international traveler screening in March 2025, the highly contagious Omicron subvariant is now responsible for an estimated 37% of COVID-19 cases in the country, according to the CDC’s latest two-week analysis ending June 7.

NB.1.8.1 is a descendant of the Omicron recombinant lineage XDV.1.5.1 and possesses several spike protein mutations that have the potential to make it more transmissible and immune-evading with respect to immunity developed from prior infections or vaccinations. Nicknamed "Nimbus" by Canadian evolutionary biologist T. Ryan Gregory, the moniker has picked up steam on social media and public health discourse.

Although total test positivity is still relatively low in the U.S. at approximately 3%, the swift rise of Nimbus to become the second most prevalent variant—second only to LP.8.1 at 38%—has raised alarm among virologists and public health professionals. Although present infection and hospitalization levels are still within control, experts are warning of the possibility of a summer spike akin to cycles experienced in earlier years.

<h2>What Are The Painful Tell-Tale Symptoms of <span rel="noindex">New Covid Variant</span>?</h2>

One of the clearest indicators of the NB.1.8.1 strain is a symptom described by patients as a "razor blade feeling" in the throat. This sore throat—dull and stabbing particularly when swallowing—is reported more often among Nimbus sufferers than in previous strains. Specialists advise rest, hydration, and painkillers to treat this symptom.

Other frequently reported symptoms are fatigue, nasal congestion, cough, fever, muscle pain, and mild breathing difficulties, in line with previous Omicron subvariants.

On May 23, the World Health Organization designated NB.1.8.1 as a "variant under monitoring," noting its rapid worldwide spread and potentially high mutations. As of May 18, it was reported in more than 22 nations and now accounts for more than 10.7% of cases of COVID-19 worldwide.

In the United States, sequences deposited at GISAID corroborate its presence in at least 14 states, with public health officials anticipating wider geographic spread over the next few weeks. Trends from foreign health agencies and increasing hospitalizations in the U.K. imply a worldwide trend of enhanced transmissibility despite incomplete sequencing data.

<h2>How Dangerous Is Nimbus COVID Variant?</h2>

Although Nimbus is certainly more infectious, to date, there is no indication that it produces more severe illness than the previous ones. The WHO and the CDC both confirm that authorized COVID-19 vaccines continue to work against this variant, although breakthrough infections may happen.

The United Kingdom Health Security Agency (UKHSA) recently posted a near 10% increase in COVID hospitalizations and a 6.9% rise in cases in one week. UKHSA's deputy director, Dr. Gayatri Amirthalingam, stressed the point that while the variant is spreading, there is no immediate evidence of heightened severity of disease.

<h2>Will Nimbus Lead to a U.S. Summer Surge?</h2>

In the past, COVID-19 has increased twice a year in the United States—in the winter and then in the summer months, from June through August. That has been the case since 2020, and having a new, more contagious variant coupled with more travel and gatherings could set off another wave.

Experts warn that while population immunity in the U.S. is very high—with more than 90% of Americans having been infected or vaccinated—immunity does fade over time. Couple this with the immune-evasive nature of NB.1.8.1, and the recipe for a possible surge in cases is there.

Presently, WHO claims that current vaccines are protective against Nimbus. New COVID vaccines for the 2025–2026 season, designed to address LP.8.1, are set to be distributed this fall. In a contentious decision, Health and Human Services Secretary Robert F. Kennedy Jr. stated that the vaccines will only be available for high-risk populations: persons above 65 years and persons between the ages of 12–64 with at least one comorbidity.

The CDC has also at the same time revised its guidelines, no longer advising routine COVID vaccination of healthy pregnant women and children—a step that most obstetricians and pediatricians object to.

With COVID wastewater levels still low and hospitalization rates stable, there is no need for mass panic. However, staying informed and cautious is key. Individuals experiencing symptoms like razor-sharp throat pain, fever, or congestion should consider testing, isolate if positive, and seek medical attention if symptoms worsen—especially if they belong to high-risk groups.

Visitors are urged to watch for regional strain patterns, maintain proper hygiene, and wear masks in crowded or poorly ventilated spaces during peak travel seasons.

NB.1.8.1, or the "Nimbus" strain, is another chapter in the continuing COVID-19 tale. Although it seems no worse than past strains, its speed and its sore, razor-like throat mark it as a reminder that the virus is still evolving.

Public health officials emphasize that vaccines continue to provide robust protection and must be employed as a first line of defense, particularly among those who are most vulnerable. While summer progresses, the emergence of Nimbus necessitates close observation, public awareness, and redoubled focus on preventive health.

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nb.1.8.1 symptoms

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omicron subvariant 2025

covid summer surge

razor blade throat covid

As the U.S. gears up for the peak summer travel season, a new COVID-19 variant known as NB.1.8.1—or informally, "Nimbus" has rapidly taken center stage in the ongoing pandemic landscape. First identified through international traveler screening in March 2025, the highly contagious Omicron subvariant is now responsible for an estimated 37% of COVID-19 cases in the country, according to the CDC’s latest two-week analysis ending June 7.NB.1.8.1 is a descendant of the Omicron recombinant lineage XDV.1.5.1 and possesses several spike protein mutations that have the potential to make it more transmissible and immune-evading with respect to immunity developed from prior infections or vaccinations. Nicknamed "Nimbus" by Canadian evolutionary biologist T. Ryan Gregory, the moniker has picked up steam on social media and public health discourse.Although total test positivity is still relatively low in the U.S. at approximately 3%, the swift rise of Nimbus to become the second most prevalent variant—second only to LP.8.1 at 38%—has raised alarm among virologists and public health professionals. Although present infection and hospitalization levels are still within control, experts are warning of the possibility of a summer spike akin to cycles experienced in earlier years.What Are The Painful Tell-Tale Symptoms of New Covid Variant?One of the clearest indicators of the NB.1.8.1 strain is a symptom described by patients as a "razor blade feeling" in the throat. This sore throat—dull and stabbing particularly when swallowing—is reported more often among Nimbus sufferers than in previous strains. Specialists advise rest, hydration, and painkillers to treat this symptom.Other frequently reported symptoms are fatigue, nasal congestion, cough, fever, muscle pain, and mild breathing difficulties, in line with previous Omicron subvariants.On May 23, the World Health Organization designated NB.1.8.1 as a "variant under monitoring," noting its rapid worldwide spread and potentially high mutations. As of May 18, it was reported in more than 22 nations and now accounts for more than 10.7% of cases of COVID-19 worldwide.In the United States, sequences deposited at GISAID corroborate its presence in at least 14 states, with public health officials anticipating wider geographic spread over the next few weeks. Trends from foreign health agencies and increasing hospitalizations in the U.K. imply a worldwide trend of enhanced transmissibility despite incomplete sequencing data.How Dangerous Is Nimbus COVID Variant?Although Nimbus is certainly more infectious, to date, there is no indication that it produces more severe illness than the previous ones. The WHO and the CDC both confirm that authorized COVID-19 vaccines continue to work against this variant, although breakthrough infections may happen.The United Kingdom Health Security Agency (UKHSA) recently posted a near 10% increase in COVID hospitalizations and a 6.9% rise in cases in one week. UKHSA's deputy director, Dr. Gayatri Amirthalingam, stressed the point that while the variant is spreading, there is no immediate evidence of heightened severity of disease.Will Nimbus Lead to a U.S. Summer Surge?In the past, COVID-19 has increased twice a year in the United States—in the winter and then in the summer months, from June through August. That has been the case since 2020, and having a new, more contagious variant coupled with more travel and gatherings could set off another wave.Experts warn that while population immunity in the U.S. is very high—with more than 90% of Americans having been infected or vaccinated—immunity does fade over time. Couple this with the immune-evasive nature of NB.1.8.1, and the recipe for a possible surge in cases is there.Presently, WHO claims that current vaccines are protective against Nimbus. New COVID vaccines for the 2025–2026 season, designed to address LP.8.1, are set to be distributed this fall. In a contentious decision, Health and Human Services Secretary Robert F. Kennedy Jr. stated that the vaccines will only be available for high-risk populations: persons above 65 years and persons between the ages of 12–64 with at least one comorbidity.The CDC has also at the same time revised its guidelines, no longer advising routine COVID vaccination of healthy pregnant women and children—a step that most obstetricians and pediatricians object to.How Can You Stay Safe?With COVID wastewater levels still low and hospitalization rates stable, there is no need for mass panic. However, staying informed and cautious is key. Individuals experiencing symptoms like razor-sharp throat pain, fever, or congestion should consider testing, isolate if positive, and seek medical attention if symptoms worsen—especially if they belong to high-risk groups.Visitors are urged to watch for regional strain patterns, maintain proper hygiene, and wear masks in crowded or poorly ventilated spaces during peak travel seasons.NB.1.8.1, or the "Nimbus" strain, is another chapter in the continuing COVID-19 tale. Although it seems no worse than past strains, its speed and its sore, razor-like throat mark it as a reminder that the virus is still evolving.Public health officials emphasize that vaccines continue to provide robust protection and must be employed as a first line of defense, particularly among those who are most vulnerable. While summer progresses, the emergence of Nimbus necessitates close observation, public awareness, and redoubled focus on preventive health.

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