Days after a rare cancer cluster in California's Ladera Ranch made headlines, another revelation has added to the mystery. An unusual number of children and young adults got diagnosed with Ewing sarcoma, a rare type of cancer. According to Los Angeles Times, between 2013 and 2024, at least six cases of Ewing sarcoma surfaced, leaving the families of patients knee-deep in questions. According to the American Cancer Society, the cancer is so rare that only 200 children and teenagers are diagnosed in the United States every year. Mystery Behind Rare Cancer Cluster In Ladera Ranch Deepens Just when the families of patients were looking for answers, another layer of mystery unraveled after a couple of 20-year-old handwritten notes emerged, signaling towards a probable cause behind the cancer cases. The notes talk about an oil well at the site. According to The New York Post, the notes appear twice on the Department of Conservation permit, and state, "This well is not to be built over without further considerations." State oil and gas supervisor William F Guerard Jr, acting state oil and gas supervisor Kenneth Henderson and deputy supervisor RK Baker signed the final report after the well was sealed on February 26, 2002. The memos warning that no structures must be constructed above the well were reportedly written by engineer Floyd Leeson. They do not reveal why such a warning about the well was issued. Another note had an arrow pointing at the message, with the phrase: "Put on final letter." According to Los Angeles Times, Henderson could not recall why such a warning was issued, although he believes the way the well was sealed might not be "up to the current standards." Meanwhile, the Department of Conservation said that the notes could have been a "clerical error."Also read: Cancer Should Be Made Notifiable In India, Say Experts: Here’s Why A Cancer So Rare That The Cases Caught AttentionEwing sarcoma is an aggressive form of cancer that primarily affects children, teenagers, and young adults. It usually begins in the bones, although it can also develop in soft tissue. It most commonly affects people between 10 and 20 years old. Symptoms can initially be easy to dismiss because they may resemble a sports injury or ordinary growing pains. They include persistent bone pain, swelling or a lump, unexplained fever, fatigue or a bone that breaks after relatively minor trauma can sometimes signal the disease. The cancer can metastasize quickly, which is why persistent or unexplained symptoms need medical evaluation.Also read: New Clinical Trial Shows Promise In Non-Surgical Treatment Of Early-Stage Rectal Cancer Can Environmental Factors Contribute To Ewing Sarcoma Risk? Documents related to the abandonment of an old oil well reportedly contain a handwritten warning from about 20 years ago regarding the development of the site. This prompted fresh questions about what was known about the land before the modern community was built. There are also concerns about possible pesticide and herbicide exposure, with residents previously urging authorities to investigate environmental factors. However, none of these potential exposures have been shown to cause the Ewing sarcoma cases in Ladera Ranch. Even though doctors are concerned, they are of the opinion that environmental factors cannot be solely tied to Ewing sarcoma.