A new study published in The BMJ suggests that women who skip their first mammogram face a higher risk of being diagnosed with advanced breast cancer and dying from the disease. The research, released on September 24, followed over 400,000 women in Sweden for up to 25 years. As October marks Breast Cancer Awareness Month, the findings highlight the importance of early screening.Skipping the First Mammogram Can Increase RiskSince the early 1990s, Sweden has offered regular mammography screenings, which have helped reduce breast cancer deaths. Yet, a significant number of women still choose to skip their first appointment. Researchers wanted to understand the long-term impact of missing this initial screening.The study analyzed data from the Swedish mammography program and national health registries, covering nearly 433,000 women in Stockholm from 1991 to 2020. About 32 percent of women declined their first screening. Those who missed it were also less likely to attend future screenings, often leading to later-stage diagnoses and worse outcomes.Women who skipped their first mammogram were more likely to be diagnosed with advanced cancer. The risk of developing stage III breast cancer was about 1.5 times higher, and for stage IV, it was 3.6 times higher than among women who attended their first screening. Over the 25-year follow-up, nearly 1 percent of women who skipped the first mammogram died from breast cancer, compared with 0.7 percent among those who attended—a 40 percent higher mortality risk. Interestingly, the overall rate of breast cancer development was nearly the same in both groups, around 7.7 percent, indicating that the increased deaths were due to delayed detection, not more cases of the disease.How Mammograms Affect Breast Cancer Risk?Mammograms use low-dose X-rays to image the breast. While repeated radiation exposure can slightly increase the risk of cancer, the amount of radiation from mammography is minimal. According to the National Cancer Institute (NCI), the risk is most significant when a person undergoes multiple chest X-rays over time.A 2016 study examined women aged 40 to 74 who received annual or biennial mammograms, noting that repeated exposure could slightly raise cancer risk, particularly for women with larger breasts. However, both that study and more recent reviews conclude that the benefits of regular mammograms far outweigh the risks. Regulatory bodies like the FDA and the Mammography Quality Standards Act ensure that equipment and radiation levels remain within safe limits.Early detection remains the key: attending the first mammogram can catch breast cancer sooner, improve treatment outcomes, and ultimately save lives.
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