Health and Me

Tanya Dutt

Type 2 Diabetes And High Blood Pressure Now Affect 1 In 8 Americans, Study Links Combo To Early Death Risk

Type 2 Diabetes And High BP Now Affect 1 In 8 Americans, Study Links Combo To Early Death Risk

A new long-term study has revealed a troubling health trend in the United States: the number of Americans living with both <span>type 2 diabetes</span> and <span>high blood pressure</span> has doubled over the last two decades, with 1 in 8 adults now affected. Even more concerning is the steep rise in mortality risk associated with this dual diagnosis—suggesting that the combo of these two chronic diseases may be deadlier than previously understood.

Published in the peer-reviewed journal Diabetes Care, the study spans nearly 20 years and highlights how a rapidly increasing population is living with multiple metabolic risk factors—a condition that significantly raises the odds of heart disease, stroke, kidney failure, and early death.

Researchers at Columbia University's Mailman School of Public Health mined health information from close to 49,000 American adults who took part in the National Health and Nutrition Examination Survey from 1999 through 2018. The National Center for Health Statistics conducted the survey, which captures interviews, laboratory tests, and physical exams to measure the health of the country.

According to the study, only 6% of Americans in 1999 suffered from both type 2 diabetes and high blood pressure. By 2018, it had risen to 12%, or about 1 in 8 adults. Those with both conditions were more than twice as likely to die from any cause and three times more likely to die from heart disease than those with neither condition.

"Even having co-existing prediabetes and high blood pressure was linked to up to 19% greater risk of death," said lead researcher Dr. Nour Makarem, assistant professor of epidemiology at Columbia University.

This is important because it indicates that heightened risk begins even before someone officially qualifies by clinical criteria as having diabetes or hypertension.

<h2>Why This Compounds To Health Risks?</h2>

Having either condition on its own—type 2 diabetes or high blood pressure—already raises one's risk for severe complications but when they occur together, their interaction in the cardiovascular system is much more destructive.

Approximately two out of three patients with type 2 diabetes have high blood pressure or are prescribed medication for it. Among individuals with both disease states, about 33% died over a median 9-year follow-up period.

For individuals with only one condition, the mortality rate remained at 20–22%, whereas individuals with neither condition suffered from a mere 6% fatality during the same period of time.

The research identified that in comparison with individuals with:

Hypertension alone, developing both conditions increased the risk for all-cause mortality by 66% as well as cardiovascular death by 54%.

Type 2 diabetes alone, but with both conditions, overall risk of death was 25% higher and greater than two-fold increased cardiovascular mortality.

<h2>Why This Disease Pair Is So Deadly?</h2>

Both type 2 diabetes and high blood pressure are "silent killers." Alone, they tend to produce no discernible symptoms until complications—such as stroke, heart failure, or kidney damage—arise. Combined, however, they provide a deadly combination of cardiovascular stress.

Diabetes disables the body's ability to keep blood sugar in balance. High glucose levels destroy blood vessels and organs by repeated damage.

Hypertension makes the heart work harder to circulate blood, which hardens and weakens the arteries.

When both conditions occur together, this speeds up the deterioration of the arteries, kidneys, and heart, making heart attack, stroke, and end-stage renal disease requiring dialysis or transplantation more likely.

<h2>Early Warning Signs That Are Often Missed</h2>

Another significant takeaway of the research is that the danger of death starts even prior to a full-blown diagnosis. Prediabetic and high-blood-pressure persons—even if they are below diagnostic levels—had a 19% greater risk of mortality.

Although type 2 diabetes can quietly develop without apparent symptoms, there are some early warning signs that should never be overlooked—particularly if you're at risk. The sooner you detect diabetes, the less complicated it is to control and prevent long-term complications. Even slight symptoms deserve a chat with your doctor.

- One of the first and most indicative symptoms of high blood sugar is urinating more often, particularly at night. As blood glucose increases, the kidneys work around the clock to flush out the excess glucose. When they're unable to keep pace, glucose leaks into the urine, causing more frequent trips to the bathroom.

- Too much sugar in the urine not only impacts hydration—but also is a breeding ground for bacteria and yeast. This increases the likelihood of infections in the urinary tract and yeast infections, particularly in women. If you find that you have persistent infections that are difficult to clear, you might want to be tested.

- Another visible clue is the appearance of dark, velvety patches of skin, typically found in body folds like the neck, armpits, or groin. These areas may indicate insulin resistance—a common precursor to diabetes.

- If you’re eating regularly but still feel hungry all the time, your cells may not be properly absorbing glucose. As a result, your body stays in a constant state of seeking energy, driving persistent hunger.

- Ironically, even though you are hungrier, you may actually lose weight unexpectedly. Since there's not enough glucose flowing into cells, your body starts to break down muscle and fat for energy.

- This energy shortage also leads to constant fatigue and weakness. You could be tired, even with a good night's rest. Dehydration caused by frequent urination only adds to that pervasive fatigue.

- Another troubling symptom is blurred vision, which can appear and disappear. High blood glucose can harm the tiny blood vessels in the eyes, leading to more severe conditions—blindness, if not treated.

- Most people experience a tingling or numb feeling in their hands or feet. This is caused by nerve damage from years of high blood sugar levels. Refereed to as diabetic neuropathy, this can also result in long-term chronic pain or loss of sensation.

This result highlights the importance of early screening and proactive prevention measures, particularly for individuals in their 30s and 40s who are unaware they're at risk. The research also reignites debate around various forms of diabetes, many of which have different risks:

Type 1 Diabetes: Autoimmune condition in which the pancreas releases no insulin.

Type 2 Diabetes: A metabolic disorder in which the body fails to utilize insulin. Frequently associated with obesity, a diet lacking in nutritious foods, and physical inactivity.

Prediabetes: A silent diabetes precursor with no warning signs.

Gestational Diabetes: Appears during pregnancy and increases risk of type 2 diabetes in the future.

Of these, type 2 diabetes is the most common and can be directly associated with lifestyle modifications that are often possible.

This highlights the pressing need for public health approaches to prevent and manage these diseases and to halt these negative trends," Dr. Makarem stressed.

At present, approximately two-thirds of adults with diabetes have blood pressure above 130/80 mm Hg or are taking antihypertensive therapy.

Since most symptoms are mild or undetectable, screening is necessary on a regular basis. The American Diabetes Association suggests that all adults over the age of 45 should be screened for diabetes. If you are younger but have risk factors that include obesity, being inactive, having a poor diet, or a family history of diabetes, you need to be tested too.

Screening is typically a straightforward blood test. If normal, the ADA recommends repeat testing at three-year intervals to track changes.

As an ageing population, inactive lifestyles and obesity on the rise, the co-epidemic of diabetes and high blood pressure is set to expand unless there are systemic changes.

Health Conditions A-Z

health

heart health

type 2 diabetes

high blood pressure

diabetes and hypertension

heart disease risk

early death risk

diabetes complications

us health statistics

Add These Ayurvedic Seeds To Your Daily Diet For Vitamin C And Muscle Repair

What Is Liquid Biopsy? New Blood Test That Can Help Detect, Treat Cancer Faster

Your Kiss Might Carry More Than Love- It Could Also Spread Anxiety, New Study Finds

Health News

Reasons To Do Dancing As A Workout

Why Summer Fruits Are A Great Addition To Your Diet?

What Should You Avoid For Your Bladder?

Lower-Body Exercises For Strong Foundation

Healthy Drinks That Improve Your Digestion

World Tobacco Day: Unexpected Ways Smoking Can Affect You

Seasonal Mood Swings? How Weather Affects Mental Health

Is Calorie Counting Healthy? Dos And Don’ts

Heat-Related Illnesses That You Should Know

Menstrual Hygiene Day: Tips On Period Hygiene

​Add These High Protein Vegetarian Meals To Your Diet​

Top 10 Workouts That Burn Most Calorie

Makhana Season – Healthy &amp; Quick Foxnut Recipes

Monsoon Ahead – Tips On Building Rainy Season Immunity

Do You Have Prickly Heat Rash – Symptoms, Causes And Treatment

Healthy No-Cook Recipes You Can Try

How Do You Calorie Count – Numbers And Nutrients

Unexpected Signs Of Dehydration – Safety And Precaution Measures

Leg Exercises You Can Do At Home To Build Strength

Foods That Promote Skin Elasticity

Must-Do Chest Exercises You Can Try At Home

What Are The Symptoms Of JN.1 COVID-19 Strain?

Why Does Sleeping Become Harder As You Age?

High-Fiber Healthy Drinks You Should Try

10 Dumbbell Exercise Variations For Upper-Body Strength

A Parent’s Guide To Pets: Important Points To Consider For Your Child’s Health

Food Anxiety Is Real – How Your Food Intake Affects Your Anxiety

World Osteoporosis Month: Ways To Strengthen Your Bones

Brain Exercises To Keep You Cognitively Sharp

Easy Recipes To Make When You Don’t Wish To Cook

Physical Signs Of High Cortisol

9 Healthy Plant-Based Protein Rich Dishes To Try

What Happens When You Have Low Blood Pressure?

Throw These Toxic Bathroom Items Away To Protect Your Health

This Is What Cricket Superstar Virat Kohli Eats In A Day

Signs You Are Experiencing Sensory Overload

Shoulder Exercises You Should Do For Defined Shoulders

Best Foods To Eat When You Are Fasting

​Ghee For Ayurveda: Why It Should Be A Part Of Your Diet​

Symptoms Of Ovarian Cancer You Should Know

A new long-term study has revealed a troubling health trend in the United States: the number of Americans living with both type 2 diabetes and high blood pressure has doubled over the last two decades, with 1 in 8 adults now affected. Even more concerning is the steep rise in mortality risk associated with this dual diagnosis—suggesting that the combo of these two chronic diseases may be deadlier than previously understood.Published in the peer-reviewed journal Diabetes Care, the study spans nearly 20 years and highlights how a rapidly increasing population is living with multiple metabolic risk factors—a condition that significantly raises the odds of heart disease, stroke, kidney failure, and early death.Researchers at Columbia University's Mailman School of Public Health mined health information from close to 49,000 American adults who took part in the National Health and Nutrition Examination Survey from 1999 through 2018. The National Center for Health Statistics conducted the survey, which captures interviews, laboratory tests, and physical exams to measure the health of the country.According to the study, only 6% of Americans in 1999 suffered from both type 2 diabetes and high blood pressure. By 2018, it had risen to 12%, or about 1 in 8 adults. Those with both conditions were more than twice as likely to die from any cause and three times more likely to die from heart disease than those with neither condition."Even having co-existing prediabetes and high blood pressure was linked to up to 19% greater risk of death," said lead researcher Dr. Nour Makarem, assistant professor of epidemiology at Columbia University.This is important because it indicates that heightened risk begins even before someone officially qualifies by clinical criteria as having diabetes or hypertension.Why This Compounds To Health Risks?Having either condition on its own—type 2 diabetes or high blood pressure—already raises one's risk for severe complications but when they occur together, their interaction in the cardiovascular system is much more destructive.Approximately two out of three patients with type 2 diabetes have high blood pressure or are prescribed medication for it. Among individuals with both disease states, about 33% died over a median 9-year follow-up period.For individuals with only one condition, the mortality rate remained at 20–22%, whereas individuals with neither condition suffered from a mere 6% fatality during the same period of time.The research identified that in comparison with individuals with:Hypertension alone, developing both conditions increased the risk for all-cause mortality by 66% as well as cardiovascular death by 54%.Type 2 diabetes alone, but with both conditions, overall risk of death was 25% higher and greater than two-fold increased cardiovascular mortality.Why This Disease Pair Is So Deadly?Both type 2 diabetes and high blood pressure are "silent killers." Alone, they tend to produce no discernible symptoms until complications—such as stroke, heart failure, or kidney damage—arise. Combined, however, they provide a deadly combination of cardiovascular stress.Diabetes disables the body's ability to keep blood sugar in balance. High glucose levels destroy blood vessels and organs by repeated damage.Hypertension makes the heart work harder to circulate blood, which hardens and weakens the arteries.When both conditions occur together, this speeds up the deterioration of the arteries, kidneys, and heart, making heart attack, stroke, and end-stage renal disease requiring dialysis or transplantation more likely.Early Warning Signs That Are Often MissedAnother significant takeaway of the research is that the danger of death starts even prior to a full-blown diagnosis. Prediabetic and high-blood-pressure persons—even if they are below diagnostic levels—had a 19% greater risk of mortality.Although type 2 diabetes can quietly develop without apparent symptoms, there are some early warning signs that should never be overlooked—particularly if you're at risk. The sooner you detect diabetes, the less complicated it is to control and prevent long-term complications. Even slight symptoms deserve a chat with your doctor.- One of the first and most indicative symptoms of high blood sugar is urinating more often, particularly at night. As blood glucose increases, the kidneys work around the clock to flush out the excess glucose. When they're unable to keep pace, glucose leaks into the urine, causing more frequent trips to the bathroom.- Too much sugar in the urine not only impacts hydration—but also is a breeding ground for bacteria and yeast. This increases the likelihood of infections in the urinary tract and yeast infections, particularly in women. If you find that you have persistent infections that are difficult to clear, you might want to be tested.- Another visible clue is the appearance of dark, velvety patches of skin, typically found in body folds like the neck, armpits, or groin. These areas may indicate insulin resistance—a common precursor to diabetes.- If you’re eating regularly but still feel hungry all the time, your cells may not be properly absorbing glucose. As a result, your body stays in a constant state of seeking energy, driving persistent hunger.- Ironically, even though you are hungrier, you may actually lose weight unexpectedly. Since there's not enough glucose flowing into cells, your body starts to break down muscle and fat for energy.- This energy shortage also leads to constant fatigue and weakness. You could be tired, even with a good night's rest. Dehydration caused by frequent urination only adds to that pervasive fatigue.- Another troubling symptom is blurred vision, which can appear and disappear. High blood glucose can harm the tiny blood vessels in the eyes, leading to more severe conditions—blindness, if not treated.- Most people experience a tingling or numb feeling in their hands or feet. This is caused by nerve damage from years of high blood sugar levels. Refereed to as diabetic neuropathy, this can also result in long-term chronic pain or loss of sensation.This result highlights the importance of early screening and proactive prevention measures, particularly for individuals in their 30s and 40s who are unaware they're at risk. The research also reignites debate around various forms of diabetes, many of which have different risks:Type 1 Diabetes: Autoimmune condition in which the pancreas releases no insulin.Type 2 Diabetes: A metabolic disorder in which the body fails to utilize insulin. Frequently associated with obesity, a diet lacking in nutritious foods, and physical inactivity.Prediabetes: A silent diabetes precursor with no warning signs.Gestational Diabetes: Appears during pregnancy and increases risk of type 2 diabetes in the future.Of these, type 2 diabetes is the most common and can be directly associated with lifestyle modifications that are often possible.This highlights the pressing need for public health approaches to prevent and manage these diseases and to halt these negative trends," Dr. Makarem stressed.At present, approximately two-thirds of adults with diabetes have blood pressure above 130/80 mm Hg or are taking antihypertensive therapy.Since most symptoms are mild or undetectable, screening is necessary on a regular basis. The American Diabetes Association suggests that all adults over the age of 45 should be screened for diabetes. If you are younger but have risk factors that include obesity, being inactive, having a poor diet, or a family history of diabetes, you need to be tested too.Screening is typically a straightforward blood test. If normal, the ADA recommends repeat testing at three-year intervals to track changes.As an ageing population, inactive lifestyles and obesity on the rise, the co-epidemic of diabetes and high blood pressure is set to expand unless there are systemic changes.

type 2 diabetes and high blood pressure now affect 1 in 8 americans, study links combo to early death risk

Health & Wellness

New Cancer Therapy Increases Survival Rate By 40%: Study

new cancer therapy increases survival rate by 40%: study

Fitness

Exercise Proven ‘Better Than Drugs’ To Prevent Colon Cancer Recurrence, Study Trial Shows

exercise proven ‘better than drugs’ to prevent colon cancer recurrence, study trial shows

Colon Cancer Is Rising In Millennials- But This One Symptom Still Feels Too Embarrassing To Talk About

colon cancer is rising in millennials- but this one symptom still feels too embarrassing to talk about

More Than A Diagnosis: Cancer Survivors Share The Small Wins That Helped Them Heal

national cancer survivors day: 'more than a diagnosis' - cancer survivors share the small wins that helped them heal

Cancer therapy is ever-evolving with new tests, treatments and pills- and in the middle of it is a revolutionary technology known as <span>liquid biopsy</span>. Just to think of a simple blood test that can diagnose cancer in its early stages, predict how a tumor will respond to treatment, and help doctors to change medications before cancer has a chance to develop anew. That's no longer science fiction anymore. Liquid biopsy is transforming the way we detect and treat cancer giving new hope to patients and changing the face of oncology.

Unlike earlier biopsies, in which tissue has to be taken from the tumor itself—usually through surgery or needle biopsies—a liquid biopsy is as easy as a blood test. This blood is then tested for circulating tumor DNA (ctDNA) or shed tumor cells in the blood. These bits contain the genetic material of the tumor and enable physicians to learn about the molecular nature of the cancer without gaining direct access to the tumor.

The latest versions of this test can even identify small, sinister changes in proteins—providing important clues about what a tumor might do and whether it is developing resistance to therapy.

A recent study published in The New England Journal of Medicine which was presented at the American Society of Clinical Oncology annual meeting illustrates just how potent liquid biopsy can be. The study involved individuals with estrogen-fueled metastatic breast cancer—a sub-type that is generally treated with medications that attack specific proteins on cancer cells.

With time, tumors evolve and these mutations can make treatments ineffective. In the research, scientists employed liquid biopsies to identify such protein mutations as far back as nine months prior to when they could be seen on conventional imaging scans. Early detection enabled doctors to change treatments preemptively—radically enhancing outcomes.

We have highly effective treatments, but they have to wear off," said Dr. Nicholas Turner, the study's co-author and a professor of molecular oncology at The Royal Marsden Hospital. "If we can pick up the changes early, we can move quickly—before the cancer does any more damage."

<h2>How Liquid Biopsies Could Enhance Outcomes?</h2>

The research had 315 patients, all of whom had acquired mutations following treatment. The liquid biopsy findings influenced a change in treatment in half of the cohort, with the other half retaining treatment as before.

Patients who had changed their treatment were twice as likely to maintain their tumors at bay in the coming year. Liquid biopsies could identify mutations up to nine months before conventional scans. In 10% of the volunteers, the test showed their treatment was no longer working, before symptoms or scans could detect it.

These results indicate a significant change in the way we monitor cancer and make medication changes—equipping clinicians and patients with sooner insights and more tailored treatment alternatives.

While this most recent study focused on breast cancer, liquid biopsy is being designed for a broad spectrum of cancers. A case in point is lung cancer, where liquid biopsies are already producing results 16 days sooner than traditional tissue biopsies, based on pilot data from the UK's National Health Service (NHS).

This quicker turnaround enables patients to initiate life-extending, targeted treatments sooner—potentially avoiding the lag that allows cancer to develop further.

NHS National Clinical Director for Cancer, Professor Peter Johnson, captured the potential of liquid biopsies perfectly:

"They are taking us into a new age of personalized cancer treatment… and we can see the difference this test is already making."

In 2022, Australian scientists reported in The New England Journal of Medicine that liquid biopsy could predict whether individuals with early-stage colon cancer required chemotherapy following surgery. This enabled numerous patients to safely avoid chemotherapy, sparing them its energy-sapping side effects without sacrificing for treatment effectiveness.

Dr. Jeanne Tie, senior research fellow at the Walter and Eliza Hall Institute of Medical Research in Australia and lead author of the study, underlined that liquid biopsies could soon become routine tools in early cancer treatment and management, but availability still differs around the world.

The secret of this groundbreaking test is its capacity for analyzing ctDNA, or pieces of tumor DNA circulating in the bloodstream. These pieces provide a molecular snapshot of the tumor, exposing important genetic mutations that reveal:

<ul><li>How aggressive the cancer is</li><li>Whether it's responding to current treatment</li><li>Which treatments are most likely to be effective</li></ul>

By detecting these changes earlier, liquid biopsies allow physicians to match patients with targeted treatments—drugs that are customized to a tumor's own individual genetic signature. Chief Scientific Officer for England Professor Dame Sue Hill welcomed this technology, "This technology is revolutionizing care and enabling clinicians to match patients sooner with potentially life-prolonging targeted therapies."

Liquid biopsy is not only a more accurate or quicker test—it's also cheaper and less invasive. One independent health economics review in the UK estimated that liquid biopsies would save the NHS as much as £11 million annually in lung cancer treatment alone.

Moreover, by minimizing the necessity for repeat scans, invasive biopsies, or cycles of unwanted chemotherapy, the test is also improving quality of life for many patients.

As the technology becomes even more advanced, researchers are looking to utilize it for:

<ul><li>Pancreatic and gallbladder cancer</li><li>Monitoring cancer growth and treatment response in real-time</li><li>Screening healthy people for early cancer signs—before symptoms even begin</li></ul>

liquid biopsy

cancer blood test

tumor dna detection

metastatic breast cancer

personalized cancer care

early cancer diagnosis

ctdna testing

Cancer therapy is ever-evolving with new tests, treatments and pills- and in the middle of it is a revolutionary technology known as liquid biopsy. Just to think of a simple blood test that can diagnose cancer in its early stages, predict how a tumor will respond to treatment, and help doctors to change medications before cancer has a chance to develop anew. That's no longer science fiction anymore. Liquid biopsy is transforming the way we detect and treat cancer giving new hope to patients and changing the face of oncology.Unlike earlier biopsies, in which tissue has to be taken from the tumor itself—usually through surgery or needle biopsies—a liquid biopsy is as easy as a blood test. This blood is then tested for circulating tumor DNA (ctDNA) or shed tumor cells in the blood. These bits contain the genetic material of the tumor and enable physicians to learn about the molecular nature of the cancer without gaining direct access to the tumor.The latest versions of this test can even identify small, sinister changes in proteins—providing important clues about what a tumor might do and whether it is developing resistance to therapy.A recent study published in The New England Journal of Medicine which was presented at the American Society of Clinical Oncology annual meeting illustrates just how potent liquid biopsy can be. The study involved individuals with estrogen-fueled metastatic breast cancer—a sub-type that is generally treated with medications that attack specific proteins on cancer cells.With time, tumors evolve and these mutations can make treatments ineffective. In the research, scientists employed liquid biopsies to identify such protein mutations as far back as nine months prior to when they could be seen on conventional imaging scans. Early detection enabled doctors to change treatments preemptively—radically enhancing outcomes.We have highly effective treatments, but they have to wear off," said Dr. Nicholas Turner, the study's co-author and a professor of molecular oncology at The Royal Marsden Hospital. "If we can pick up the changes early, we can move quickly—before the cancer does any more damage."How Liquid Biopsies Could Enhance Outcomes?The research had 315 patients, all of whom had acquired mutations following treatment. The liquid biopsy findings influenced a change in treatment in half of the cohort, with the other half retaining treatment as before.Patients who had changed their treatment were twice as likely to maintain their tumors at bay in the coming year. Liquid biopsies could identify mutations up to nine months before conventional scans. In 10% of the volunteers, the test showed their treatment was no longer working, before symptoms or scans could detect it.These results indicate a significant change in the way we monitor cancer and make medication changes—equipping clinicians and patients with sooner insights and more tailored treatment alternatives.While this most recent study focused on breast cancer, liquid biopsy is being designed for a broad spectrum of cancers. A case in point is lung cancer, where liquid biopsies are already producing results 16 days sooner than traditional tissue biopsies, based on pilot data from the UK's National Health Service (NHS).This quicker turnaround enables patients to initiate life-extending, targeted treatments sooner—potentially avoiding the lag that allows cancer to develop further.NHS National Clinical Director for Cancer, Professor Peter Johnson, captured the potential of liquid biopsies perfectly:"They are taking us into a new age of personalized cancer treatment… and we can see the difference this test is already making."In 2022, Australian scientists reported in The New England Journal of Medicine that liquid biopsy could predict whether individuals with early-stage colon cancer required chemotherapy following surgery. This enabled numerous patients to safely avoid chemotherapy, sparing them its energy-sapping side effects without sacrificing for treatment effectiveness.Dr. Jeanne Tie, senior research fellow at the Walter and Eliza Hall Institute of Medical Research in Australia and lead author of the study, underlined that liquid biopsies could soon become routine tools in early cancer treatment and management, but availability still differs around the world.How Does Liquid Biopsy Work?The secret of this groundbreaking test is its capacity for analyzing ctDNA, or pieces of tumor DNA circulating in the bloodstream. These pieces provide a molecular snapshot of the tumor, exposing important genetic mutations that reveal:How aggressive the cancer isWhether it's responding to current treatmentWhich treatments are most likely to be effectiveBy detecting these changes earlier, liquid biopsies allow physicians to match patients with targeted treatments—drugs that are customized to a tumor's own individual genetic signature. Chief Scientific Officer for England Professor Dame Sue Hill welcomed this technology, "This technology is revolutionizing care and enabling clinicians to match patients sooner with potentially life-prolonging targeted therapies."Liquid biopsy is not only a more accurate or quicker test—it's also cheaper and less invasive. One independent health economics review in the UK estimated that liquid biopsies would save the NHS as much as £11 million annually in lung cancer treatment alone.Moreover, by minimizing the necessity for repeat scans, invasive biopsies, or cycles of unwanted chemotherapy, the test is also improving quality of life for many patients.As the technology becomes even more advanced, researchers are looking to utilize it for:Pancreatic and gallbladder cancerMonitoring cancer growth and treatment response in real-timeScreening healthy people for early cancer signs—before symptoms even begin

what is liquid biopsy? new blood test that can help detect, treat cancer faster

How The Drug 'Creon' Works And Why Its Shortage Is Forcing Cancer Patients To Skip Meals

How The Drug Creon Works And Why Its Shortage Is Forcing Cancer Patients To Skip Meals

Drinking Even In Moderation Can Increase Your Cancer Risk In This Organ, Finds Study

drinking even in moderation can increase your cancer risk in this organ, finds study

Nutrition

This 'Sweet and Sour' Fruit Juice Can Help Ease Sore Throat While Reducing Your Cancer Risk

this unexpected fruit juice can not only help with sore throat but also reduce cancer risk, study suggests

<span>Cancer</span> patients as well as patients with conditions such as cystic fibrosis and chronic pancreatitis are now confronted with an acute shortage of an essential medication—Creon. This pancreatic <span>enzyme replacement therapy</span> (PERT) is crucial to digesting food, one of the most fundamental of human activities which becomes all but impossible for those with pancreatic insufficiency.

The consequences are frightening- patients are forgoing meals, dividing up doses, and driving more than 30 miles just to receive the capsules. The effect is not just nutritional but life-threatening, because not being able to properly digest food can make a person vulnerable to infection, make them weaker, and restrict access to life-saving treatment like chemotherapy.

Creon is the brand name of pancreatic enzyme replacement therapy that is used to manage exocrine pancreatic insufficiency (EPI)—a disease in which the pancreas is unable to produce enzymes to help digest food. This inability can be due to a variety of reasons, such as pancreatic cancer, cystic fibrosis, chronic pancreatitis, and complications after surgery like gastric-bypass or pancreatic surgery.

For individuals with EPI, Creon® is not merely a supportive therapy—it is a lifeline. It allows them to extract nutrition from food and sustain body weight, energy, and immune capacity. Without it, patients experience persistent diarrhea, abdominal pain, malnutrition, and ultimately, reduced quality of life and survivability.

The Government in the UK has prolonged the Serious Shortage Protocol (SSP) for Creon until November 2025, enabling pharmacists to dispense a reduced quantity without a fresh prescription. Although the policy tries to make things more accessible, this is a short-term solution to an ongoing and hazardous shortage.

One survey carried out by the National Pharmacy Association (NPA), surveying more than 300 pharmacies, shows a dire picture. A whopping 96% of these pharmacies are struggling to get Creon, the essential pancreatic enzyme replacement therapy. Additionally, 89% have the same shortages with other drugs like Nutrizym and Pancrex. This shortage is making many patients go distances of over 30 miles just to get a pharmacy that will fill their prescriptions. Even more alarming, many patients are said to be skipping meals or cutting their doses in order to stretch their short supplies, jeopardizing their health and wellbeing in the process.

The shortage is primarily due to "European-wide supply issues" and production limitations on the drug that have caused interruptions in the manufacture and distribution of Creon, as reported by the Department of Health and Social Care. The interruptions are not specific to Creon but point to systemic weaknesses in pharmaceutical production.

In Creon's case, though, the end result is worse. Unlike certain drugs that can be skipped or substituted for others, Creon® is instantly vital with each patient meal. There is no "respite" from taking it, and even temporary discontinuation can cause health emergencies.

<h2>How is the Shortage of the Drug Affecting Cancer Patients?</h2>

The psychological and physical strain on the patients cannot be estimated. As Alfie Bailey-Bearfield, Pancreatic Cancer UK's Head of Influencing &amp; Health Improvement, stressed, "It's completely unacceptable that they are still taking desperate steps which risk their health, wellbeing, and their suitability for treatment."

Patients going without meals in order to cut corners on enzyme capsules put themselves at significant risk of malnutrition and severe weight loss. Not only does this compromise the immune response of the body, it lowers tolerance to chemotherapy, effectively excluding patients from life-sustaining or curative therapy. The medical risk is not abstract—it's real and measurable.

Exocrine Pancreatic Insufficiency (EPI) is more prevalent than many people know. In the UK alone, approximately 61,000 patients need pancreatic enzyme therapy. Reasons are:

<ul><li>Pancreatic cancer (especially advanced)</li><li>Cystic fibrosis</li><li>Chronic and acute pancreatitis</li><li>Pancreatic surgery or gastric bypass</li><li>Untreated celiac disease or inflammatory bowel disease</li></ul>

EPI results in undigested food entering the colon, leading to bloating, gas, cramps, and diarrhea. With time, the nutrient deficiencies cause weight loss, bone loss, and even increased cardiovascular risk. In children, it impairs growth and development.

Unlike regular prescriptions, Creon is not prescribed with a set amount. It has to be individualized for each patient, for each meal, and even for each snack. The dosing is 3,000 to 36,000 enzyme units per capsule. For comparison, a normal pancreas will release up to 720,000 units for a small meal.

Patients are instructed to self-regulate according to their intake, so that a consistent and plentiful source becomes not only the preferred but also the necessary mode of correct dosing. Under shortages, this individualized dosing is a luxury many cannot enjoy.

Healthcare providers and patient advocacy groups alike are demanding immediate government action. Bailey-Bearfield and Picard have issued public calls for a strategic restructuring to solve manufacturing constraints and enhance distribution systems.

"This crisis continues to put people's health at risk, and they cannot afford to wait any longer," Bailey-Bearfield implored.

It takes not only stockpiling but also long-term planning, such as investment in alternative manufacturing hubs, local production incentives, and better global supply chain coordination.

cancer

creon shortage

pancreatic cancer treatment

cystic fibrosis drug

enzyme replacement therapy

cancer patient health

digestive drug crisis

creon availability issues

Cancer patients as well as patients with conditions such as cystic fibrosis and chronic pancreatitis are now confronted with an acute shortage of an essential medication—Creon. This pancreatic enzyme replacement therapy (PERT) is crucial to digesting food, one of the most fundamental of human activities which becomes all but impossible for those with pancreatic insufficiency.The consequences are frightening- patients are forgoing meals, dividing up doses, and driving more than 30 miles just to receive the capsules. The effect is not just nutritional but life-threatening, because not being able to properly digest food can make a person vulnerable to infection, make them weaker, and restrict access to life-saving treatment like chemotherapy.Creon is the brand name of pancreatic enzyme replacement therapy that is used to manage exocrine pancreatic insufficiency (EPI)—a disease in which the pancreas is unable to produce enzymes to help digest food. This inability can be due to a variety of reasons, such as pancreatic cancer, cystic fibrosis, chronic pancreatitis, and complications after surgery like gastric-bypass or pancreatic surgery.For individuals with EPI, Creon® is not merely a supportive therapy—it is a lifeline. It allows them to extract nutrition from food and sustain body weight, energy, and immune capacity. Without it, patients experience persistent diarrhea, abdominal pain, malnutrition, and ultimately, reduced quality of life and survivability.The Government in the UK has prolonged the Serious Shortage Protocol (SSP) for Creon until November 2025, enabling pharmacists to dispense a reduced quantity without a fresh prescription. Although the policy tries to make things more accessible, this is a short-term solution to an ongoing and hazardous shortage.One survey carried out by the National Pharmacy Association (NPA), surveying more than 300 pharmacies, shows a dire picture. A whopping 96% of these pharmacies are struggling to get Creon, the essential pancreatic enzyme replacement therapy. Additionally, 89% have the same shortages with other drugs like Nutrizym and Pancrex. This shortage is making many patients go distances of over 30 miles just to get a pharmacy that will fill their prescriptions. Even more alarming, many patients are said to be skipping meals or cutting their doses in order to stretch their short supplies, jeopardizing their health and wellbeing in the process.The shortage is primarily due to "European-wide supply issues" and production limitations on the drug that have caused interruptions in the manufacture and distribution of Creon, as reported by the Department of Health and Social Care. The interruptions are not specific to Creon but point to systemic weaknesses in pharmaceutical production.In Creon's case, though, the end result is worse. Unlike certain drugs that can be skipped or substituted for others, Creon® is instantly vital with each patient meal. There is no "respite" from taking it, and even temporary discontinuation can cause health emergencies.How is the Shortage of the Drug Affecting Cancer Patients?The psychological and physical strain on the patients cannot be estimated. As Alfie Bailey-Bearfield, Pancreatic Cancer UK's Head of Influencing & Health Improvement, stressed, "It's completely unacceptable that they are still taking desperate steps which risk their health, wellbeing, and their suitability for treatment."Patients going without meals in order to cut corners on enzyme capsules put themselves at significant risk of malnutrition and severe weight loss. Not only does this compromise the immune response of the body, it lowers tolerance to chemotherapy, effectively excluding patients from life-sustaining or curative therapy. The medical risk is not abstract—it's real and measurable.What is EPI?Exocrine Pancreatic Insufficiency (EPI) is more prevalent than many people know. In the UK alone, approximately 61,000 patients need pancreatic enzyme therapy. Reasons are:Pancreatic cancer (especially advanced)Cystic fibrosisChronic and acute pancreatitisPancreatic surgery or gastric bypassUntreated celiac disease or inflammatory bowel diseaseEPI results in undigested food entering the colon, leading to bloating, gas, cramps, and diarrhea. With time, the nutrient deficiencies cause weight loss, bone loss, and even increased cardiovascular risk. In children, it impairs growth and development.Unlike regular prescriptions, Creon is not prescribed with a set amount. It has to be individualized for each patient, for each meal, and even for each snack. The dosing is 3,000 to 36,000 enzyme units per capsule. For comparison, a normal pancreas will release up to 720,000 units for a small meal.Patients are instructed to self-regulate according to their intake, so that a consistent and plentiful source becomes not only the preferred but also the necessary mode of correct dosing. Under shortages, this individualized dosing is a luxury many cannot enjoy.Healthcare providers and patient advocacy groups alike are demanding immediate government action. Bailey-Bearfield and Picard have issued public calls for a strategic restructuring to solve manufacturing constraints and enhance distribution systems."This crisis continues to put people's health at risk, and they cannot afford to wait any longer," Bailey-Bearfield implored.It takes not only stockpiling but also long-term planning, such as investment in alternative manufacturing hubs, local production incentives, and better global supply chain coordination.

how the drug 'creon' works and why its shortage is forcing cancer patients to skip meals

Ishita Roy

COVID-19 Cases In India Continue To Surge, Kerala Tops The List

India Records 3,395 Active COVID-19 Cases, 26 Deaths, Kerala And Maharashtra Among Worst-Hit States

india records 3,395 active covid-19 cases, 26 deaths, kerala and maharashtra among worst-hit states

High PCOS Prevalence Found Among Young Women In Delhi, Finds Study

high pcos prevalence found among young women in delhi, finds study

Cook County Health Grapples With Lost Grants Amid Federal Pullback

cook county health grapples with lost grants amid federal pullback

COVID-19 cases in India continue to rise, the numbers have now touched 3,758. Kerala, the southern-most state in India has reported the highest of the cases, leading with 1,400 cases, followed by Maharashtra with 506 cases. 

On Saturday, the Union Health Ministry released a data, which registered 685 more active cases, another data was released on Sunday, which reported 360 new infections, which had been recorded within 24 hours. 

Apart from that, two COVID-19 deaths were also reported during the same time, in Kerala and Karnataka. In Karnataka, a 63-year-old man who had comorbidities including pulmonary TB, squamous cell carcinoma of buccal mucosa, and was also tested positive for COVID-19, passed away. While in Kerala, a 24-year-old woman with COVID-19 and pre-existing conditions like sepsis, hypertension, and decompensated chronic liver disease (DCLD) also passed away, reported the Health Ministry. 

As per the Ministry of Health and Family Welfare figures, in the last 24 hours, Kerala reported 64 new cases, Maharashtra reported 18, while Delhi reported 61 new cases. 

In Delhi, a 60-year-old woman who had been tested positive with COVID-19 also passed away, as per the official. This has also marked the first death in the capital during the current wave. The woman is said to have undergone surgery for intestinal obstruction, and incidentally found out that she was also COVID-19 positive. 

Gurugram too reported a spike in COVID-19 cases after two and a half years. Dr Alka Singh, who is the Civil Surgeon also urged people to not ignore flu-like symptoms. From the cases reported earlier, it has been found that people who had been suffering from flu were in fact, COVID-19 positive. 

Four new Covid-19 cases were reported in Gurugram on Sunday, bringing the total during the current surge to 23, with 12 active cases. All patients have mild symptoms and are isolating at home. The health department collected 97 samples for testing the same day.

Maharashtra reported 65 new Covid-19 cases on Sunday, bringing the total since January 1 to 814. Pune accounted for 31, Mumbai 22, Thane nine, Kolhapur two, and Nagpur one. The state currently has 506 active cases, with 300 recoveries so far, according to the health department.

<strong>ALSO READ: <a href="https://www.healthandme.com/health-news/india-records-3395-active-covid-19-cases-26-deaths-kerala-and-maharashtra-among-worst-hit-states-article-151765683" data-type="tilCustomLink">India Records 3,395 Active COVID-19 Cases, 26 Deaths, Kerala And Maharashtra Among Worst-Hit States</a></strong>

In Odisha, active cases have risen to 12, all presenting mild symptoms and placed in isolation, said Nilakantha Mishra, the state’s Director of Public Health.

Andhra Pradesh’s information minister K Parthasarathi urged people to remain vigilant amid a national rise in infections, advising caution in crowded public spaces such as railway stations, bus stands, and airports.

West Bengal registered 82 new cases in the past 24 hours, taking the number of active cases in the current wave to 287. Six people were discharged after testing negative. Updated figures from the state health department are awaited.

Punjab has six active Covid-19 cases, with five reported from Ludhiana. One death has occurred. Among the infected are two children of the deceased, who are asymptomatic and in quarantine. The remaining cases include a returnee from Kerala and two individuals who had contact with travellers from high-infection states.

In view of the rising Covid-19 cases, the Karnataka government on Saturday issued an advisory urging the public to wear masks in crowded spaces, maintain physical distancing, and follow hygiene protocols.

Union minister of state for health and AYUSH, Prataprao Jadhav, assured last week that the central government is fully prepared to manage any emerging Covid-19 situation.

COVID-19 cases in India continue to rise, the numbers have now touched 3,758. Kerala, the southern-most state in India has reported the highest of the cases, leading with 1,400 cases, followed by Maharashtra with 506 cases. On Saturday, the Union Health Ministry released a data, which registered 685 more active cases, another data was released on Sunday, which reported 360 new infections, which had been recorded within 24 hours. Apart from that, two COVID-19 deaths were also reported during the same time, in Kerala and Karnataka. In Karnataka, a 63-year-old man who had comorbidities including pulmonary TB, squamous cell carcinoma of buccal mucosa, and was also tested positive for COVID-19, passed away. While in Kerala, a 24-year-old woman with COVID-19 and pre-existing conditions like sepsis, hypertension, and decompensated chronic liver disease (DCLD) also passed away, reported the Health Ministry. As per the Ministry of Health and Family Welfare figures, in the last 24 hours, Kerala reported 64 new cases, Maharashtra reported 18, while Delhi reported 61 new cases. India Impacted By COVID-19In Delhi, a 60-year-old woman who had been tested positive with COVID-19 also passed away, as per the official. This has also marked the first death in the capital during the current wave. The woman is said to have undergone surgery for intestinal obstruction, and incidentally found out that she was also COVID-19 positive. Gurugram too reported a spike in COVID-19 cases after two and a half years. Dr Alka Singh, who is the Civil Surgeon also urged people to not ignore flu-like symptoms. From the cases reported earlier, it has been found that people who had been suffering from flu were in fact, COVID-19 positive. Four new Covid-19 cases were reported in Gurugram on Sunday, bringing the total during the current surge to 23, with 12 active cases. All patients have mild symptoms and are isolating at home. The health department collected 97 samples for testing the same day.Maharashtra reported 65 new Covid-19 cases on Sunday, bringing the total since January 1 to 814. Pune accounted for 31, Mumbai 22, Thane nine, Kolhapur two, and Nagpur one. The state currently has 506 active cases, with 300 recoveries so far, according to the health department.ALSO READ: India Records 3,395 Active COVID-19 Cases, 26 Deaths, Kerala And Maharashtra Among Worst-Hit StatesIn Odisha, active cases have risen to 12, all presenting mild symptoms and placed in isolation, said Nilakantha Mishra, the state’s Director of Public Health.Andhra Pradesh’s information minister K Parthasarathi urged people to remain vigilant amid a national rise in infections, advising caution in crowded public spaces such as railway stations, bus stands, and airports.West Bengal registered 82 new cases in the past 24 hours, taking the number of active cases in the current wave to 287. Six people were discharged after testing negative. Updated figures from the state health department are awaited.Punjab has six active Covid-19 cases, with five reported from Ludhiana. One death has occurred. Among the infected are two children of the deceased, who are asymptomatic and in quarantine. The remaining cases include a returnee from Kerala and two individuals who had contact with travellers from high-infection states.In view of the rising Covid-19 cases, the Karnataka government on Saturday issued an advisory urging the public to wear masks in crowded spaces, maintain physical distancing, and follow hygiene protocols.Union minister of state for health and AYUSH, Prataprao Jadhav, assured last week that the central government is fully prepared to manage any emerging Covid-19 situation.

Type 2 Diabetes And High Blood Pressure Now Affect 1 In 8 Americans, Study Links Combo To Early Death Risk

Quick Stories

What Is Liquid Biopsy? New Blood Test That Can Help Detect, Treat Cancer Faster

How The Drug 'Creon' Works And Why Its Shortage Is Forcing Cancer Patients To Skip Meals

COVID-19 Cases In India Continue To Surge, Kerala Tops The List

Health Conditions A-Z

Add These Ayurvedic Seeds To Your Daily Diet For Vitamin C And Muscle Repair

What Is Liquid Biopsy? New Blood Test That Can Help Detect, Treat Cancer Faster

Your Kiss Might Carry More Than Love- It Could Also Spread Anxiety, New Study Finds