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What if I told you that success has a neurological backup? This implies that all your brain activities and processes play a significant role in achieving success. Emily Mcdonald, a neuroscientist, recently took to Instagram to suggest three science-backed secrets to success that nobody talks about.
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Secret number one is the saying "You are who you surround yourself with", which has a ton of neuroscience to back it up. There is brainwave synchronization, where your brain activity syncs up with the people you interact with. There is something in psychology called the chameleon effect, where we subconsciously become like the people we surround ourselves with. Albert Bandura, a renowned social psychologist, gave the theory of vicarious learning, also known as observational learning or social learning, wherein individuals acquire knowledge and skills by observing others' behaviors and consequences rather than through direct experience.
Moreover, there is also something called automatic goal contagion, where you subconsciously adopt the goals of the people around you. You think that your goals are yours, but are they actually?
Secret number two is that your brain will subconsciously block you from the success that you desire if your goals are not wired into your brain to feel safe. Remember, your brain is designed to survive and not thrive. As per Emily, this is where self-sabotage comes into play—things like procrastination and excuses—and you don't even know why you're doing it. It's because your brain is afraid of your goals.
Secret number three is that your brain will, 100% of the time, work to keep you in alignment with your identity. This is because the default mode network of the brain, which is responsible for your subconscious behaviors, is also responsible for your identity and your ego. This is the power of stepping into the identity or the persona of who you want to be.
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Nuts, Especially Walnuts
Nuts are widely regarded as great for brain health, but not all nuts offer the same benefits. Walnuts stand out for having the highest ratio of omega-3 “good fats” to omega-6 “bad fats.”
Wild Fish
Fresh, fatty fish are a powerful source of omega-3 fatty acids, known for their anti-inflammatory properties. Brain-healthy choices include salmon, grouper, and halibut. It's best to opt for fresh and wild-caught fish, as farm-raised varieties are often fed with unnatural additives.
Leafy Greens And Asparagus
Leafy greens are rich in fiber, folate, lutein, and beta-carotene. Options like bok choy, asparagus, or broccolini, when steamed or sautéed with olive oil, garlic, and a pinch of salt at the end, make easy, healthy dinners. Though not leafy, asparagus is a favorite due to its fiber content and quick cooking time. A healthy gut, supported by fiber, also benefits brain health.
Tomatoes
Tomatoes are a great source of lycopene, an antioxidant related to beta-carotene. Antioxidants combat inflammation and oxidative stress, helping prevent neurodegeneration. Grape tomatoes or tomato medleys are versatile — great for salads, sauces, or appetizers with mozzarella, basil, and olive oil.
Berries And Walnuts
Blueberries, eaten almost daily, are rich in flavonoids — potent antioxidants and anti-inflammatory agents that may reduce stress effects on the brain. Pairing them with walnuts and steel-cut oats makes a perfect breakfast. A drizzle of honey or maple syrup and a pinch of salt elevate the flavor.
Olive Oil
Olive oil is full of monounsaturated fats that help lower LDL cholesterol and raise HDL cholesterol. It’s ideal for cooking, dressings, and dips. Just avoid deep-frying with it.
Turmeric And Ginger
Turmeric’s active compound, curcumin, may benefit brain health by disrupting amyloid plaques linked to Alzheimer’s. Pair it with black pepper for better absorption. Ginger adds flavor and fibre and may even help with mental clarity.
Coffee And Tea
Rich in flavonoids and phytonutrients, coffee and tea support brain metabolism. Moderate caffeine intake can enhance concentration and productivity.
Popcorn
For a fun, healthy snack, try homemade popcorn. Air-popped kernels with olive oil, nutritional yeast, and a dash of salt make for a satisfying treat — a smarter option than chips.
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For all major diseases, early detection is key to improving treatment outcomes. However, when it comes to rare diseases, it is unpredictable, making it more challenging to diagnose. In such a scenario, Artificial Intelligence (AI) is playing a major role -- from early diagnosis to treatment, said health experts on Rare Disease Day.
Rare Disease Day is annually observed on February 28 to raise awareness about the lesser-known conditions and the underlying challenges for people suffering from them.
While many of the rare disorders are genetic, they often also surface without any prior family history. In some cases, they are diagnosed in infancy, while in others the manifestation is years late.
The advanced AI technology is, however, now enabling clinicians to better understand the patients’ genetic profiles and patterns that were not clearer earlier. The technology is also paving the way for earlier and more accurate diagnoses, bringing hope to thousands of patients worldwide.
“AI is revolutionizing the fight against rare diseases by speeding up diagnosis, research, and development of treatments. Rare diseases often take years to diagnose because of the lack of data, overlapping symptoms, and unclear diagnosis,” Dr. Vinit Banga, Director, Neurology, Fortis Escorts Hospital, Faridabad, told HealthandMe.
“AI algorithms can process medical records, genetic information, and images to identify patterns that may escape human detection, allowing for earlier and more accurate diagnoses,” he added.
In a February paper published in the journal Nature, researchers from the Shanghai Jiao Tong University in China presented an AI system called DeepRare -- a multi-agent system for rare disease differential diagnosis decision support, powered by large language models, integrating more than 40 specialized tools.
Using the specialized tools and knowledge sources, the agentic AI system generates ranked diagnostic hypotheses for rare diseases. Each of the tools was also accompanied by reasoning that links the conclusions to verifiable medical evidence.
Similarly, Harvard University-based researchers in a paper also published in the Nature journal in 2025 described an AI tool called PopEVE, which can identify genetic variants most likely to cause severe disease or death.
The model was able to identify more than 100 novel alterations responsible for undiagnosed, rare genetic diseases.
"AI is cutting short the diagnostic odyssey from years to weeks. Large-scale genomic projects help create a vital reference architecture for India and the global community,” Dr. Sudheendra Rao N R, MBBS, PhD, Scientific Advisor, Organization for Rare Diseases India, told HealthandMe.
By integrating deep phenotyping with AI, clinicians can decipher unknown genetic variants and accelerate the development of both repurposed and next-generation precision-therapies, the expert added.
AI can also help researchers identify new drug targets for the treatment of rare conditions.
Dr. Banga said that AI is also instrumental in accelerating drug development by processing enormous amounts of biomedical data to discover new targets for drugs and repurpose existing ones. Importantly, AI is cutting down on time and expenses.
“Machine learning algorithms enable the prediction of patient responses to particular treatments, making it possible to develop personalized treatment strategies,” the expert said.
Further, AI-enabled infrastructure is helping to achieve geographic neutrality, delivering the same caliber of healthcare screening to rural villages and Tier-3 cities as to Tier-1 hubs, ensuring a high-quality healthcare gateway that is no longer defined by where the patient lives.
Moreover, AI-based platforms bring together researchers from across the globe, making it easier to share data.
The World Health Organization (WHO) defines a rare disease as an often debilitating, chronic, or degenerative condition affecting 1 or fewer per 1,000 population.
Rare diseases do not have epidemiological data, are at high risk of misdiagnosis, and often also lack effective treatments.
According to the WHO ICD-11 (International Classification of Diseases), there are over 5,500 rare diseases. It also assigns unique identifiers (URIs) to them for better tracking.
There are estimated to be over 7,000 distinct rare diseases affecting more than 300 million people globally.
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Do you know that congenital hypothyroidism, a rare disability, affects about 1 in 2,500–3,000 newborns globally, but in India, the incidence is higher -- approximately 1 in 1,000 births.
India records nearly 26 million births annually, with an estimated 10,000 babies born each year with Congenital Hypothyroidism.
This means 27 babies are born every day in India, with the condition that more than one is born every hour. Early treatment within the first 2 weeks of life can ensure normal brain development, while delayed treatment can reduce IQ by 30–50 points.
Congenital Hypothyroidism (CH) is a condition present at birth in which a baby’s thyroid gland does not produce enough thyroid hormone.
The thyroid is a small gland located in the neck. It produces a hormone called thyroxine (T4), which is essential for brain development, growth, and overall body metabolism. The thyroid hormone is especially important in the first few weeks of life.
The thyroid hormone helps in:
If a baby does not receive enough thyroid hormones soon after birth, it can lead to permanent intellectual disability and growth problems.
The good news is that congenital hypothyroidism is easily detectable and completely treatable if identified early.
What Causes Congenital Hypothyroidism? What Are The Symptoms?
Congenital Hypothyroidism may occur because:
One of the biggest challenges with Congenital Hypothyroidism is that most babies look completely normal at birth.
However, over time, some signs may appear:
How Is Congenital Hypothyroidism Detected?
1. Newborn Screening Test (Heel-Prick Test)
2. Confirmatory Blood Tests
If the screening test is abnormal, the doctor will order:
3. Thyroid Scan
In some cases, imaging tests are needed. The ultrasound of the neck (less accurate) and Nuclear Medicine Thyroid scan (more accurate) may be done to check whether the gland is absent, small, or misplaced. However, treatment should not be delayed while waiting for imaging.
When Should Treatment Start?
Treatment should begin as early as possible -- ideally within the first 14 days of life. Starting treatment within the first two weeks allows normal brain development.
Delaying treatment increases the risk of permanent intellectual disability.
Doctors will monitor:
Initially, blood tests are done every 2–4 weeks, then less frequently as the child grows. Proper follow-up ensures the dose remains correct. Some babies may need treatment for life.
In certain cases, doctors may reassess thyroid function after 3 years of age to see whether the condition is temporary or permanent. Most children who receive early and proper treatment grow up with completely normal intelligence and physical development.
Can Congenital Hypothyroidism Be Prevented? Why Early Screening Is So Important
Most cases cannot be prevented. However:
A baby with Congenital Hypothyroidism may look perfectly healthy. Without screening, diagnosis may be delayed until symptoms appear—by then, brain development may already be affected.
With early testing the diagnosis is simple; treatment is affordable; and outcome is excellent. But without testing:
Congenital Hypothyroidism is one of the most preventable causes of intellectual disability in children. A small heel-prick test in the first few days of life can protect your baby’s brain forever.
If you are expecting a baby or have a newborn, speak to your doctor about newborn thyroid screening.
Early diagnosis. Simple treatment. Normal life.
Credit: Health Ministry
Prime Minister Narendra Modi today launched the nationwide Human Papillomavirus (HPV) vaccination campaign for girls aged 14 years from Rajasthan's Ajmer.
The initiative marks a decisive step towards eliminating cervical cancer through timely HPV vaccination. Cervical cancer remains the second most common cancer among women in India. Nearly 80,000 new cases and over 42,000 deaths are reported annually in the country.
"Today, I have had the opportunity to launch the HPV vaccine campaign from Ajmer. This campaign is an important step towards empowering women and daughters of this country,” PM Modi said.
“For us, this was a sensitive issue tied to the insult of our sisters and daughters, one that made them ill. That is why we resolved it at a crucial turning point in their mission,” he added.
The World Health Organization has also lauded India's mission to launch the HPV vaccine and prevent the risk of cervical cancer.
“We are leaving no stone unturned to ensure that the daughters of the country are healthy and prosperous. The objective of this initiative is the prevention of cervical cancer," the Prime Minister, earlier wrote in a post on social media platform X.
The nationwide program, based on expert recommendations of the National Technical Advisory Group on Immunization (NTAGI), will target girls aged 14 years.
At 14, the HPV vaccine offers maximum preventive benefit, well before potential exposure to the virus.
"By prioritizing prevention at the right age, the program is expected to provide lifelong protection and significantly reduce the future burden of cervical cancer in the country," the government said.
“The HPV vaccine works best at 9-14 years, before exposure, and when the immune response is strongest. Studies show effectiveness is highest in younger age groups and decreases with age,” Dr. Parmod Kumar, Associate Professor in Medical Oncology, AIIMS Jodhpur, shared on X.
Vaccination under the national program will be voluntary and free of cost.
The HPV vaccination will be conducted exclusively at designated government health facilities, including Ayushman Arogya Mandirs (Primary Health Centers), Community Health Centers, Sub-District and District Hospitals, and Government Medical Colleges.
Despite being preventable, cervical cancer continues to claim the life of a woman every two minutes globally, and the WHO South-East Asia Region bears nearly one-quarter of the global burden.
Dr. Catharina Boehme, Officer-in-Charge, WHO South-East Asia, stated that the introduction of HPV vaccination at a national scale in India "will have a far-reaching impact". It will accelerate progress not only for the country, but for the region and the world, she said.
“This landmark step, led at the highest level of government, reflects India’s strong commitment to protecting adolescent girls from cervical cancer," said Dr. Boehme.
With today’s milestone, nine of the 10 countries in the Region now include HPV vaccination in their national immunization programs.
The WHO global targets for 2030 include vaccinating 90 percent of girls by age 15, screening 70 percent of women by ages 35 and 45, and ensuring 90 percent of women with pre-cancer and invasive cancer receive appropriate treatment.
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