As the winter season sets in, the US Centers for Disease Control and Prevention (CDC) expects the 2025–26 fall and winter respiratory virus season to bring roughly the same number of hospitalizations linked to Covid-19, flu, and RSV as last year. Still, there are ways to lower your risk of becoming seriously ill from these infections, and vaccination remains one of the most effective measures.According to preliminary CDC data from October 2024 through May 2025, around 1 million people were hospitalized with the flu last season, and there were as many as 130,000 flu-related deaths. Between October 2024 and September 2025, CDC estimates also show nearly 540,000 Covid-19 hospitalizations and up to 63,000 deaths due to the virus. As the season of respiratory illness is here, let’s take a look at some common vaccine questions.Who Can Get Covid Shots?The CDC recommends that everyone aged 6 months and older, including pregnant individuals, discuss getting the updated Covid-19 vaccine with their health care provider this season. This marks a shift from earlier years, when the guidance broadly encouraged most people to get vaccinated.“This fall, the CDC hasn’t issued a universal recommendation for the Covid-19 vaccine,” explained Dr. Dan Barouch, director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center. “Instead, it’s being offered under a shared-decision model, where people are encouraged to talk to their doctor about the risks and benefits before deciding.”When Is The Best Time To Get The Covid Vaccine?Dr. Sarah Dupont, a family medicine physician at Emory Healthcare and assistant professor at Emory University School of Medicine, suggests getting the Covid-19 vaccine in October or early November for the best protection through winter.How Effective Is The Covid Vaccine?A recent study published in the New England Journal of Medicine found that last year’s updated Covid-19 vaccines were about 39% effective in preventing hospitalizations and 64% effective in preventing deaths among US veterans.Who Can Get A Flu Shot This Year?The CDC advises that most people aged 6 months and older should get a flu shot every year. Generally, one dose is sufficient each season. However, children receiving the flu vaccine for the first time should get two doses, spaced about four weeks apart, to build stronger immunity.How Effective Is The Flu Shot?The effectiveness of this year’s flu vaccine won’t be known until after the season ends. For reference, during the 2024–25 respiratory virus season, the CDC estimated that flu vaccines were 42% to 56% effective in adults.Who Can Get An RSV Immunization?RSV vaccines are recommended for adults aged 75 and older, and for those aged 50 to 74 who face a higher risk of severe illness, according to the CDC. A single dose can offer protection for at least two years in older adults.To safeguard infants, protection can come either from maternal vaccination during pregnancy or from an antibody shot administered to the baby after birth.When Is The RSV Vaccine Available?Eligible adults can get the RSV vaccine at any point, though the CDC notes that late summer to early fall is ideal. For mothers, the vaccine is typically available from September through January, while infants can receive their antibody shot from October through March.Beyond vaccination, there are other ways to stay healthy this season. Health experts urge people to stay home when they feel unwell to prevent spreading illness. Those who want to be extra cautious can avoid crowded indoor spaces during winter, and wearing a mask remains a personal option for reducing both your own risk and that of others.