As people age, so does the concern about cognitive decline and dementia. With no absolute cure for Alzheimer's and other types of dementia, efforts to prevent it have become a critical public health priority. Perhaps one of the most widespread perceptions among wellness communities and social circles is that doing puzzles—whether Sudoku, crosswords, or jigsaw—will safeguard the brain against cognitive loss. But is there any science to support this brain-bolstering hype? Can a daily puzzle really help prevent dementia?

Based on the National Poll on Healthy Aging by the University of Michigan, most adults between the ages of 50 and 64 are concerned about getting dementia. Nonetheless, only 5% mentioned that they had talked with their doctors about taking preventive measures to lower this risk. Instead, most used brain teasers or vitamins in the hope of protecting their minds.

Although large health organizations such as the World Health Organization and the Global Council on Brain Health have dispelled the efficacy of supplements in preventing dementia, mentally stimulating activities—such as puzzles—continue to enjoy increasing support in scientific literature, albeit with qualifications.

A large UK observational study, which is part of the online PROTECT study of brain aging, used data from more than 19,000 healthy adults aged between 50 and 93. Participants who participated in word or number puzzles regularly had better cognitive function in various domains, including spatial working memory, verbal reasoning, attention, and reaction time.

Notably, various puzzles appeared to challenge different areas of the brain. Puzzles with words were correlated with enhanced grammatical thinking, whereas puzzles involving numbers such as Sudoku were connected with enhancement of executive abilities such as planning and organization.

But the biggest lesson learned wasn't which puzzle was superior—it was how often people did these cognitively challenging activities. People who solved puzzles at least monthly had improved cognitive scores all around compared to those who never did.

Correlation vs. Causation: What's Reducing Dementia Risk?

Even with these encouraging correlations, specialists warn that cause-and-effect conclusions should not be drawn directly. Observational studies such as PROTECT cannot say whether puzzle-solving enhances thought or if individuals with more robust brain powers are inherently inclined to such pursuits.

Yet another limitation is that most studies have not yet separated out lifelong puzzle enthusiasts from those who started solving them later in life. It becomes challenging to determine long-term impacts of puzzle work on dementia onset individually.

The Bronx Aging Study, a 20-year longitudinal study, discovered that older adults who consistently worked on crossword puzzles postponed the onset of dementia by an average of 2.54 years. Although not a guarantee against cognitive decline, this postponement is significant and supports the theory that cognitively stimulating activities can contribute to what's called "cognitive reserve"—the brain's capacity to deal with or compensate for damage.

Role of Brain Puzzles in Preventing Dementia

So, then, can puzzles prevent dementia? Not exactly. But can they slow down cognitive decline? Maybe. And unlike supplements, puzzles pose no health risk, so they are a safe and possibly useful part of a larger brain health plan.

As Dr. Teresa Gomes-Osman cited in the 2020 Lancet Commission Report on Dementia Prevention, lifestyle factors that can be changed—like education, exercise, treating depression, limiting air pollution exposure, and others—combined explain as much as 40% of dementia cases. Mental stimulation, such as puzzle-solving, is a perfect fit on the "cognitive reserve" side of this equation.

Which Puzzles Work Best To Reduce Dementia Risk?

Sudoku

Excellent for building numerical reasoning, Sudoku exercises the mind in logical reasoning, pattern identification, and problem-solving. Its deceptively simple format hides the sophisticated cognitive stimulation it provides.

Riddles

These exercise critical thinking, recall of memory, and lateral thinking. Riddles also hone verbal abilities and understanding in everyday applications.

Word Search

This tried-and-tested puzzle aids in better vocabulary, concentration, and observation. It enhances the brain's liaison with language—a fundamental thinking function during aging.

Jigsaw Puzzles

Fun and healing, jigsaws engage both the visual and memory parts of the brain. The coordination involved assists with motor functions and spatial understanding, and they can also be an excellent social activity.

Ways Puzzles Help Keep your Brain Healthy

Puzzles must be viewed as part of the brain-health puzzle, but only one piece. Puzzles work as part of a multi-pronged strategy to prevent dementia that also includes:

Physical exercise: Exercise maintains neuroplasticity and circulation to the brain.

Social engagement: Solitude is a recognized risk factor; remaining socially engaged maintains emotional and mental well-being.

Balanced nutrition: A Mediterranean-type diet with lots of leafy greens, whole grains, and healthy fat supports brain function.

Medical management: Treating hearing loss, hypertension, and diabetes is crucial for brain health.

While we’re still a long way from declaring puzzles as the magic bullet against dementia, research continues to reinforce the value of mental activity in supporting brain health. Puzzles challenge the brain, offer therapeutic value, and—when combined with a healthy lifestyle—can be an enjoyable and effective part of cognitive aging.

So the next time you grab a crossword or open up a Sudoku grid, you may be doing your brain a long-term favor.

On the day of World Malaria Day, as we raise awareness on the dangers posed by this mosquito-borne disease, let's delve a bit deeper into how malaria is different from the other mosquito-borne diseases.

Dengue vs Malaria

Both malaria and dengue are transmitted by female mosquitoes and cause severe illness in humans. There are certain similarities between the two diseases and the mosquito species, which is why the patients and diagnoses are often confused.

As per the co-Principal Investigator, Dr Charles Guissou, for the Target Malaria, a vector control research alliance's Target Malaria Burkina Faso at the Institut de Recherche en Sciences de la Santé, "Dengue and malaria are two very different diseases caused by different pathogens and different mosquito species." “Misdiagnosis between malaria and dengue is common, and this can then contribute to inappropriate medical care.”

Every year, malaria causes 200 million cases worldwide, leading to 600,000 deaths. Many of these cases are from Africa, where children and pregnant women pay the highest price. The World Health Organization (WHO) has also reported that in 2022, Africa was home to 95% of malaria cases and 95% of malaria deaths. The global incidence of dengue has grown significantly in recent decades. Cases reported to WHO increased from 505,430 in 2000 to 6.5 million in 2023.

Dr Ajay Gupta, Head & Director - Internal Medicine, Max Super Speciality Hospital, Vaishali also points out the key differences between malaria and other mosquito-borne diseases. He says, "Malaria is caused by Plasmodium parasites, transmitted through the bite of infected Anopheles mosquitoes. In contrast, dengue, chikungunya, and Zika viruses are transmitted by Aedes mosquitoes. This distinction in the type of mosquito also reflects differences in peak biting times—Anopheles mosquitoes bite during nighttime, while Aedes mosquitoes are daytime biters."

"Another key difference lies in complications and disease progression. Malaria, especially caused by Plasmodium falciparum, can progress rapidly to severe illness with cerebral involvement, anemia, kidney failure, and even death if not promptly treated. Dengue, on the other hand, is known for a sudden drop in platelet count and risk of hemorrhage. Chikungunya commonly leads to prolonged joint pain, sometimes lasting weeks or even months after the infection clears," notes the doctor.

There is also a difference between how the mosquitoes that spread dengue and malaria.

The Aedes Mosquito

It is responsible for spreading dengue and has white stripes down the center of the thorax. It also has a resting position where its body is kept low and parallel to the ground, with the proboscis angled downward. It is slender, and the wings have distinctive white markings.

The Anopheles Mosquito

It is responsible for causing malaria and has long palps. It is dark in color and the resting position follows it abdomen at a 45-degree angle to the surface.

Zika Virus

Zika is a viral infection also transmitted by Aedes mosquitoes, which is the first difference from malaria, in the species of mosquito that causes it. As per the WHO, those with Zika virus do not tend to experience symptoms, and if they do, it includes rash, fever, conjunctivitis, and muscle and joint pain. The symptoms are also what makes it different. They appear from 3 to 14 days after being bitten.

Chikungunya

This is also caused by Aedes mosquitoes, and the symptoms usually appear within 4 to 8 days after infection. The symptoms include fever, joint pain, headaches, and nausea.

Yellow Fever

This is caused by Aedes and haemagogus mosquitoes. People who are infected with this virus do not get sick and experience only mild symptoms. As per the Centers for Disease Control and Prevention (CDC), 12% of people who have symptoms develop serious illness, which includes organ failure and jaundice.

The key difference between all other mosquito-borne diseases and malaria is the species of the mosquito that causes it. While all the others are caused by Aedes, malaria is caused by the Anopheles.

What Else Makes Malaria Different Other Than The Type Of Mosquito That Causes It?

Drinking Beer Could Increase Chances Of Infection

According to the scientists at the University of Emory, in their 2010 study, they found that beer produces an odour in your body that is irresistible to the malaria-carrying mosquitoes.

It Could Take Four Years To Develop Symptoms

There are rare strains of this disease which could in fact take months or even years to get diagnosed. In one of the rare cases, malaria was diagnosed four years later the individuals were infected, reported UK's The Telegraph.

Malaria And Its Connection With Snow White

In 1943, Disney was tasked with creating a film to promote public health awareness. The result? The Winged Scourge — a rather unusual PSA where the Seven Dwarfs learn how to fight off malaria-spreading mosquitoes.

Malaria Has Killed Four Popes, And At Least Eight Presidents Have Suffered From It

George Washington battled malaria, and the disease is also believed to have claimed the lives of Pope Leo and Pope Sixtus—just a few of its prominent victims.

Malaria And India

The doctor also points out that diagnosis and treatment also vary. "Malaria is typically confirmed with a blood smear or rapid diagnostic test and is treated with specific antimalarial drugs. There is no antiviral treatment for dengue, chikungunya, or Zika—management is primarily supportive," he says.

In India, we often see a spike in these illnesses during and after the monsoon season, However, malaria control efforts—such as early diagnosis, insecticide-treated bed nets, and vector control—have significantly reduced the burden in recent years.

"Preventive strategies like eliminating stagnant water, using mosquito repellents, and ensuring proper sanitation are universally effective. But recognizing the distinct nature of malaria is key to prompt diagnosis and management," notes Dr Gupta.

In 2022, about 1 in 5, which is around 702,880, people died due to cardiovascular diseases (CVD) in the United States. There are many factors around you that affect your heart health. Things like what food you eat, whether the area you live in is polluted or not and also what kind of lifestyle you lead. There are many risk factors for heart diseases like high blood pressure, high cholesterol levels or smoking, which are key risk factors according to the Centers of Disease Control and Prevention (CDC). The CDC explains about 47% of US citizens have at least one of these three risk factors.

Another risk factor could be the place you live in. A new study published in the European Society of Cardiology April 2025 revealed that the walkability of a neighborhood can play a big role for your cardiovascular health. The study revealed that individuals living in areas with low walkability had a 5% higher risk of developing CVD compared to those in very walkable neighborhoods. Interestingly, even in neighborhoods that improved in walkability over time, the risk of CVD remained about 5% higher for those who started in low-walkability areas, possibly due to the lasting effects of earlier sedentary habits.

What Makes A Neighborhood Walk-Friendly?

To figure out how walkable a neighborhood is, the researchers in the study looked at several things. They checked how many people lived in the area (population density), how many shops were nearby, if there were parks and green spaces, and if there were sidewalks to walk on. They also considered if different types of buildings were mixed together (like shops and homes), if there was good public transportation, and how well the streets connected to each other. All these things together helped them decide how easy it was to walk around in a certain neighborhood.

Researchers studied over three million adults who were at least 40 years old and didn't have any heart problems when the study started. The researchers kept track of how walkable each person's neighborhood was for 13 years. They also checked if the walkability of these neighborhoods stayed the same, got better, or got worse during that time.

The findings of this study support what doctors have known for a long time: moving your body is good for your health, especially your heart. What's interesting is that you don't need to do intense workouts to see the benefits. Even small amounts of activity, like walking your dog in a park or carrying your groceries home from the store, can make a difference. These little bursts of energy throughout the day can add up and help lower your risk of getting heart disease.

Should People Opt For More Walkable Places?

A report from 2023 from Smart Growth America found that less than 7% of people in America actually live in very walkable urban neighborhoods. Interestingly, studies have shown that minority groups often live in more walkable neighborhoods. However, these same groups are also more likely to suffer from heart and blood sugar problems. This might be because even in walkable areas, factors like safety, clean environments, and good sidewalks and parks might not be available in all neighborhoods.

Even if you don't live in a very walkable area, there are still things you can do to move more. You might need to get a little creative! You can try lifting weights or doing yoga while you watch TV. If you drive to the store, park a little further away so you have to walk more. Take the stairs instead of the elevator. Stand up and move around when you're on the phone, have walking meetings if possible, and make sure to get up and stretch every hour.

During a recent conference on drug addiction, the US Health Secretary Robert F Kennedy Jr. shared a personal story about his own battle with drug addiction and his journey to recovery. He also emphasized on the importance of helping young people find meaning in life. His speech at the Rx and Illicit Drug Summit in Nashville, Tennessee, emphasized the need for prevention, community, and spiritual support in addressing substance abuse.

RFK Jr.'s Struggle With Addiction

Kennedy revealed that he was addicted to heroin for 14 years. It started during his teenage years. During that time, he constantly promised to quit to himself and his family, but he felt powerless to follow through.

“I didn’t want to be someone who woke up every morning thinking about drugs,” he said, describing the feeling of being unable to “keep contracts” with himself. He shared that he felt like he was born with a hole inside him—something many addicts feel—that he tried to fill with drugs.

He also called addiction "a source of misery, but also a symptom of misery". He stressed that threats of overdose or ruined lives often have little impact on those who are already suffering. “Every addict feels that way in one way or another... and the only thing that works are drugs,” he said.

His message to the 3,000 attendees focused on how deeper issues like hopelessness and disconnection from community contribute to addiction.

Finding A Way Out Through Faith

RFK Jr. went on to describe his recovery journey that started after he read a book by Swiss psychiatrist Carl Jung, who suggested that people who believe in God tend to recover more effectively. This inspired him and rekindled his faith in God. He began to attend the 12-step meetings. God was mentioned in his speech over 20 times, and it was noted that spirituality played a big role in his healing.

RFK Jr. also acknowledged criticism from public health experts and was interrupted several times by hecklers. Without directly engaging them, he said he tries to learn from everyone—“even the people who give me the finger.”

Prevention Through Purpose

While RFK Jr. did praise tools like Suboxone, methadone, and access to rehab, his main focus remained on prevention. “We have this whole generation of kids who’ve lost hope in their future,” he said. According to him, restoring connections to family, community, and purpose is crucial.

He encouraged policy changes that would promote stronger family bonds—such as phone-free meals—and more opportunities for young people to engage in service. “The best way to overcome hopelessness,” he said, “is to wake up each day and pray, ‘Please make me useful to another human being today.’”

While Kennedy’s speech resonated with many, others pushed back on his approach. Researcher Caleb Banta-Green, who was removed after shouting, later said that while spirituality can be helpful, science-based interventions must be prioritized and properly funded.

While Kennedy’s speech resonated with many, others pushed back on his approach. Researcher Caleb Banta-Green, who was removed after shouting, later said that while spirituality can be helpful, science-based interventions must be prioritized and properly funded.