As people age, so does the concern about cognitive decline and dementia. With no absolute cure for Alzheimer's and other types of dementia, efforts to prevent it have become a critical public health priority. Perhaps one of the most widespread perceptions among wellness communities and social circles is that doing puzzles—whether Sudoku, crosswords, or jigsaw—will safeguard the brain against cognitive loss. But is there any science to support this brain-bolstering hype? Can a daily puzzle really help prevent dementia?

Based on the National Poll on Healthy Aging by the University of Michigan, most adults between the ages of 50 and 64 are concerned about getting dementia. Nonetheless, only 5% mentioned that they had talked with their doctors about taking preventive measures to lower this risk. Instead, most used brain teasers or vitamins in the hope of protecting their minds.

Although large health organizations such as the World Health Organization and the Global Council on Brain Health have dispelled the efficacy of supplements in preventing dementia, mentally stimulating activities—such as puzzles—continue to enjoy increasing support in scientific literature, albeit with qualifications.

A large UK observational study, which is part of the online PROTECT study of brain aging, used data from more than 19,000 healthy adults aged between 50 and 93. Participants who participated in word or number puzzles regularly had better cognitive function in various domains, including spatial working memory, verbal reasoning, attention, and reaction time.

Notably, various puzzles appeared to challenge different areas of the brain. Puzzles with words were correlated with enhanced grammatical thinking, whereas puzzles involving numbers such as Sudoku were connected with enhancement of executive abilities such as planning and organization.

But the biggest lesson learned wasn't which puzzle was superior—it was how often people did these cognitively challenging activities. People who solved puzzles at least monthly had improved cognitive scores all around compared to those who never did.

Correlation vs. Causation: What's Reducing Dementia Risk?

Even with these encouraging correlations, specialists warn that cause-and-effect conclusions should not be drawn directly. Observational studies such as PROTECT cannot say whether puzzle-solving enhances thought or if individuals with more robust brain powers are inherently inclined to such pursuits.

Yet another limitation is that most studies have not yet separated out lifelong puzzle enthusiasts from those who started solving them later in life. It becomes challenging to determine long-term impacts of puzzle work on dementia onset individually.

The Bronx Aging Study, a 20-year longitudinal study, discovered that older adults who consistently worked on crossword puzzles postponed the onset of dementia by an average of 2.54 years. Although not a guarantee against cognitive decline, this postponement is significant and supports the theory that cognitively stimulating activities can contribute to what's called "cognitive reserve"—the brain's capacity to deal with or compensate for damage.

Role of Brain Puzzles in Preventing Dementia

So, then, can puzzles prevent dementia? Not exactly. But can they slow down cognitive decline? Maybe. And unlike supplements, puzzles pose no health risk, so they are a safe and possibly useful part of a larger brain health plan.

As Dr. Teresa Gomes-Osman cited in the 2020 Lancet Commission Report on Dementia Prevention, lifestyle factors that can be changed—like education, exercise, treating depression, limiting air pollution exposure, and others—combined explain as much as 40% of dementia cases. Mental stimulation, such as puzzle-solving, is a perfect fit on the "cognitive reserve" side of this equation.

Which Puzzles Work Best To Reduce Dementia Risk?

Sudoku

Excellent for building numerical reasoning, Sudoku exercises the mind in logical reasoning, pattern identification, and problem-solving. Its deceptively simple format hides the sophisticated cognitive stimulation it provides.

Riddles

These exercise critical thinking, recall of memory, and lateral thinking. Riddles also hone verbal abilities and understanding in everyday applications.

Word Search

This tried-and-tested puzzle aids in better vocabulary, concentration, and observation. It enhances the brain's liaison with language—a fundamental thinking function during aging.

Jigsaw Puzzles

Fun and healing, jigsaws engage both the visual and memory parts of the brain. The coordination involved assists with motor functions and spatial understanding, and they can also be an excellent social activity.

Ways Puzzles Help Keep your Brain Healthy

Puzzles must be viewed as part of the brain-health puzzle, but only one piece. Puzzles work as part of a multi-pronged strategy to prevent dementia that also includes:

Physical exercise: Exercise maintains neuroplasticity and circulation to the brain.

Social engagement: Solitude is a recognized risk factor; remaining socially engaged maintains emotional and mental well-being.

Balanced nutrition: A Mediterranean-type diet with lots of leafy greens, whole grains, and healthy fat supports brain function.

Medical management: Treating hearing loss, hypertension, and diabetes is crucial for brain health.

While we’re still a long way from declaring puzzles as the magic bullet against dementia, research continues to reinforce the value of mental activity in supporting brain health. Puzzles challenge the brain, offer therapeutic value, and—when combined with a healthy lifestyle—can be an enjoyable and effective part of cognitive aging.

So the next time you grab a crossword or open up a Sudoku grid, you may be doing your brain a long-term favor.

Cardiovascular-kidney-metabolic (CKM) syndrome is emerging as a major public health threat, according to new guidelines from the American Heart Association (AHA), which identify obesity as a key driver of the condition's development and progression.

The guidelines, jointly issued by the AHA and the American College of Cardiology (ACC), reframe excess weight as more than a number on the scale, describing it as a significant health risk closely linked to diabetes, chronic kidney disease and cardiovascular disease.

According to the AHA, nearly 9 in 10 adults in the United States have at least one condition associated with CKM syndrome. These include high blood pressure, abnormal cholesterol and other lipid disorders, high blood sugar, reduced kidney function and excess body weight.

With obesity rates continuing to rise, the guideline urges healthcare professionals to have prevention-focused conversations with patients about maintaining a healthy weight to reduce the risk of future heart, kidney and metabolic diseases.

“CKM syndrome is a real, rising public health threat,” said Chiadi E. Ndumele, an American Heart Association volunteer and chair of the writing committee for the new guideline.

“In terms of CKM health, weight is not just about a number on a scale — people with the same body weight can have very different health profiles. Rather, what’s most important is how fat tissue affects your metabolic health. This includes how your body manages blood sugar levels and how fat is used and stored,” Ndumele, who is also director of obesity and cardiometabolic research at Johns Hopkins University in Baltimore.

The New CKM Syndrome Guideline

Also read: Bryan Johnson's Autoimmune Gastritis: US Doctor Explains the Hidden Signs of Autoimmune Disease

The updated guideline replaces the 2013 recommendations for managing overweight and obesity. CKM syndrome itself was first formally defined by the American Heart Association in 2023.

The guideline highlights several strategies to improve the prevention and treatment of CKM syndrome:

• Use the Predicting Risk of Cardiovascular Disease EVENTs (PREVENT) equations to estimate 10-year and 30-year cardiovascular disease risk. Unlike previous tools, PREVENT incorporates kidney and metabolic health factors for a more comprehensive risk assessment.
• Screen patients for social determinants of health, including food insecurity, housing instability and financial strain, which can increase the risk of CKM syndrome.
• Promote coordinated, multidisciplinary care focused on healthy lifestyle behaviors, including physical activity, nutrition, weight management, blood pressure control, blood sugar management and cholesterol reduction.
• Alongside lifestyle interventions, use medications and surgical therapies when appropriate to manage blood pressure, cholesterol, blood sugar and obesity while protecting heart and kidney health.
• For the first time, the guideline recommends GLP-1-based therapies for select individuals with obesity and/or Type 2 diabetes who are at elevated cardiovascular risk. Metabolic and bariatric surgery is also recognised as an effective treatment option for eligible patients.

How Can CKM Syndrome Be Prevented?

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The guideline emphasizes that early lifestyle changes can significantly reduce the risk of heart attack, heart failure, stroke and kidney failure.

People are encouraged to follow the AHA's Life's Essential 8, which promotes

• regular physical activity,
• a heart-healthy diet,
• maintaining a healthy weight,
• controlling blood pressure,
• maintaining blood sugar
• better cholesterol control,
• avoiding tobacco,
• getting sufficient quality sleep.

The monsoon brings welcome relief from the heat, but it also creates conditions that make infections spread more easily among children. Parents should understand that a few common household mistakes can increase the risk of illness in children during this time of year. So, parents must exercise caution and take utmost care of their children during those rainy days.

Why Monsoon Raises Infection Risk in Children

The arrival of the monsoon often means more time spent indoors for children, muddier surroundings, and increased exposure to germs. So, the main focus of parents is on protecting their children from rain and cold weather. However, parents must understand that certain everyday habits at home may unknowingly increase the risk of respiratory infections, stomach illnesses, and mosquito-borne diseases.

Common Mistakes Of Infections In Children

So, many children can get drenched during those heavy rains and remain in wet clothes or footwear for long periods after returning from school or outdoor activities. Damp socks and shoes can create an environment where germs and fungal infections thrive. Parents should ensure that children change into dry clothes and footwear as soon as possible. Moreover, stagnant water collected in flower pots, buckets, coolers, balconies, and outdoor containers can become breeding grounds for mosquitoes, raising the chances of dengue, malaria, and chikungunya in children.

Many families keep doors and windows closed throughout the day to prevent rainwater from entering the house. However, limited air circulation can lead to the growth of mold, dampness, and indoor allergens, which may trigger respiratory infections, coughing, wheezing, and allergies in children. Even having uncovered food, improperly stored leftovers, or contaminated water can increase the risk of stomach infections, diarrhea, vomiting, and food poisoning in children.

Tips Parents Should Follow During the Monsoon

Parents should ensure that the child changes wet clothes, socks, and shoes immediately after returning home. Parents should empty and clean containers that can collect stagnant water from time to time. Use mosquito nets, screens, and child-safe mosquito repellents to prevent mosquito bites. Keep rooms well ventilated whenever the weather permits. The child should follow good hand and personal hygiene, eat freshly cooked food, and drink safe drinking water.

The parents should ensure to wash fruits and vegetables thoroughly before consumption. The child should eat a nutritious diet, sleep well, and stay hydrated to boost immunity and prevent any illness. Parents should seek immediate help if the child is having any symptoms, such as a cough or allergies, and follow the expert's guidelines. Parents should not give any medication to the child on their own without the doctor's knowledge. So, parents should stay alert during the monsoon and help the child stay healthy.

Billionaire entrepreneur Bryan Johnson, known for meticulously tracking his health and pursuing longevity, recently revealed that he has been diagnosed with Autoimmune Gastritis, an incurable autoimmune condition in which the body's immune system attacks the stomach lining.

Describing the disease on social media platform X, Johnson said: "My stomach is eating itself." He also noted that despite undergoing extensive medical evaluations over the years, the condition went undetected because autoimmune diseases often develop quietly, with symptoms that can easily be mistaken for everyday health issues such as fatigue or digestive discomfort.

According to the Centers for Disease Control and Prevention (CDC), autoimmune diseases occur when the immune system mistakenly attacks the body's own healthy cells and tissues, triggering inflammation and damage to organs or other body systems.

The burden of these conditions is significant. In May 2025, researchers from the Mayo Clinic and collaborating institutions estimated that nearly 15 million Americans are living with one or more of 105 recognized autoimmune diseases.

Symptoms Can Be Easy to Miss

Because autoimmune diseases often begin with vague, non-specific symptoms, they can remain undiagnosed for months—or even years.

Dr. Cory Rice, a US-based Functional Medicine physician, said these warning signs frequently go unnoticed until the disease has progressed.

"First and foremost, symptoms of autoimmune disease can come and go, and be on and off, or they can be more persistent in nature," he told Newsweek.

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The Hidden Signs You Shouldn't Ignore

While symptoms vary depending on the various autoimmune conditions, several early warning signs are shared across many autoimmune diseases.

According to Dr. Rice, common symptoms include:

• Fatigue
• Low-grade fever
• Joint pain
• Unexplained rashes or hives
• Dry eyes and dry mouth
• Numbness or tingling in the hands or feet
• Mouth ulcers
• Increased sensitivity to cold temperatures

He said when people suffer from fatigue, "it is usually both profound and debilitating."

Dr. Rice explained that many people try to manage this overwhelming exhaustion by relying on caffeine and other stimulants, taking thyroid medications or hormone treatments, or opting for therapies such as intravenous infusions and vitamin B12 injections.

However, when an underlying autoimmune disease is responsible, these approaches often fail to provide lasting relief.

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Why Autoimmune Diseases Are Often Diagnosed Late

One of the biggest challenges in diagnosing autoimmune diseases is that their symptoms overlap with those of many other medical conditions.

Johnson also said that "2-5 per cent of people have this (autoimmune disease). Likely more, because it hides".

Symptoms may also appear intermittently before becoming more persistent.

"It all depends on the disease process in play and the severity or progression of the disease itself in a particular person as to whether symptoms are more constant or intermittent," Rice said.

He added that many primary care physicians are not routinely trained to identify autoimmune diseases in their early stages. As a result, patients are frequently referred to specialists, including rheumatologists, only after symptoms have become more pronounced.

"Unfortunately, by this point, the autoimmune disease may already be far along in whichever parts of the body are impacted," he said.

Dr. Rice emphasized that recognizing symptoms early and obtaining a timely diagnosis can help slow disease progression and improve long-term outcomes.