Heart disease remains the leading cause of death worldwide, claiming millions of lives each year. Among its most devastating manifestations is cardiac arrest—a sudden, unexpected stoppage of heart function that, if not treated immediately, is almost always fatal. Recent research has illuminated a crucial, often overlooked fact: the warning signs of cardiac arrest can differ between men and women. Recognizing these differences is not just a matter of academic interest; it can mean the difference between life and death.Cardiac arrest is often sudden, silent, and deadly — claiming more lives globally than most people realize. But a growing body of research shows that its early warning signs may not be the same for everyone. Specifically, men and women often experience different symptoms before cardiac arrest occurs — and recognizing these differences may mean the difference between life and death.Sometimes called sudden cardiac arrest, occurs when the heart abruptly stops beating. This cessation halts blood flow to the brain and other vital organs, causing a person to lose consciousness within seconds. Without rapid intervention, such as cardiopulmonary resuscitation (CPR) or use of an automated external defibrillator (AED), death can occur within minutes.Unlike a heart attack—which is caused by a blockage in the arteries supplying the heart—cardiac arrest is primarily an electrical problem. The heart’s rhythm becomes dangerously abnormal, most commonly due to ventricular fibrillation, causing it to quiver instead of pumping blood effectively.A recent study published in The Lancet Digital Health has revealed groundbreaking findings that could reshape how we understand and respond to cardiac arrest. Researchers have now confirmed that while chest pain is the most prominent pre-symptom in men, women often experience shortness of breath in the hours leading up to a cardiac arrest episode. The data comes from community-based studies including the PRESTO study in California and the SUDS study in Oregon, which collectively examined how sex-specific symptoms could be harnessed to improve early detection and survival.According to the study, half of all individuals who experience sudden cardiac arrest have a warning symptom within 24 hours prior to the event. However, these symptoms are not uniform across genders. For women, shortness of breath emerged as the most prominent warning sign, while men most commonly reported chest pain. Other symptoms, such as palpitations, flu-like sensations, and even seizures, were also noted in a smaller subset of patients.Shortness of Breath vs Chest PainIn the recent study, researchers found that over 50% of individuals who suffered cardiac arrest had at least one warning symptom within 24 hours. Men most commonly reported chest pain, while women more frequently experienced shortness of breath. A smaller percentage of both groups experienced palpitations, flu-like symptoms, or seizures.“This is the first community-based study to evaluate sex-specific warning symptoms using real-time emergency medical service (EMS) documentation,” said Eduardo Marbán, Executive Director at the Smidt Heart Institute.Dr. Sumeet Chugh, the study’s lead investigator, emphasized the impact: “Harnessing these symptoms could guide who needs immediate emergency response. That insight could change survival rates.”What Exactly Is Cardiac Arrest?Cardiac arrest, sometimes confused with a heart attack, occurs when the heart stops beating abruptly due to an electrical malfunction. This sudden stoppage halts blood flow to the brain and other vital organs, often causing loss of consciousness within seconds. If not treated immediately — typically through CPR or defibrillation — death can occur within minutes.It’s different from a heart attack, which is caused by a blockage in the coronary arteries. However, heart attacks can trigger cardiac arrest by disrupting the heart’s electrical system.Cardiac Arrest vs. Heart AttackThe terms “heart attack” and “cardiac arrest” are often used interchangeably, but they refer to distinct medical emergencies. A heart attack is caused by a blockage that prevents blood from reaching a part of the heart muscle, leading to tissue damage. Cardiac arrest, on the other hand, is an electrical malfunction that causes the heart to stop beating altogether.While a heart attack can increase the risk of cardiac arrest—by disrupting the heart’s electrical system—not all cardiac arrests are preceded by a heart attack. Other causes include arrhythmias, enlarged heart (cardiomyopathy), severe blood loss, valvular heart disease, and electrolyte imbalances.Why Younger People Are at Increasing Risk?The rise in sudden cardiac deaths among young adults is particularly concerning. While some cases are linked to undiagnosed heart conditions such as hypertrophic cardiomyopathy or ventricular arrhythmias, others may be triggered by intense exercise, drug use, or even severe viral infections. These factors can cause the heart to beat irregularly or stop altogether, often without warning. Several factors are contributing to the alarming rise in heart disease and sudden cardiac arrests among young adults:Genetics and lifestyle: While you can’t change your genes, factors like smoking, poor diet, lack of exercise, and unmanaged stress play significant roles in heart health.Steroid abuse: Especially among gym-goers and bodybuilders, the use of steroids and growth hormones can damage heart muscles and disrupt rhythms.Undiagnosed conditions: Conditions like hypertrophic cardiomyopathy or dilated cardiomyopathy (often linked to viral infections like COVID-19) may go unnoticed until it's too late.Post-COVID heart risks: Myocarditis and lung fibrosis can lower oxygen supply and impair heart function, increasing cardiac vulnerability.Severe stress: Though rare, emotional trauma can induce cardiac events, especially in those with pre-existing conditions.Recognizing the Symptoms Before It’s Too LateFor women, these symptoms may present more subtly — and are more likely to be mistaken for stress or anxiety. That’s why public health messaging must evolve to include gender-specific information. While some cardiac arrests strike without any warning, many cases are preceded by symptoms that are often misread or dismissed:Chest pain or tightnessShortness of breathPalpitations or irregular heartbeatFainting or dizzinessExtreme fatigueNausea or stomach painSudden sweating or lightheadednessWhat You Can Do Today to Prevent Cardiac Arrest?Preventing cardiac arrest begins with understanding your risk factors and taking proactive steps to protect your heart health. Experts recommend the following:Routine screening: Start annual checks for blood pressure, cholesterol, and blood sugar levels after age 18.Know your numbers: Aim for total cholesterol Get vaccinated and treated for viral infections: Viruses like COVID-19 can lead to myocarditis and long-term heart damage.Stop smoking and avoid exposure to secondhand smoke.Maintain physical activity but with caution. People over 40 or with a family history should consult a doctor before starting high-intensity workouts.As cardiac events among young people rise and symptoms continue to vary across genders, researchers believe integrating biometric data, wearable tech, and AI-powered health tools can offer early detection solutions in the near future.