Could Your Baby's Constant Giggling Be A Warning Sign? Detecting Pediatric Brain Tumors

Updated Oct 15, 2024 | 08:00 PM IST

SummaryWorried about your child’s frequent headaches or vision changes? Pediatric brain tumors can cause subtle signs. Early diagnosis is key—learn the symptoms and when to seek medical help for peace of mind.
Pediatric Brain Tumors: What Every Parent Should Know

Pediatric Brain Tumors: What Every Parent Should Know

Raj and Meera always felt blessed by their baby boy, Aarav, who seemed to radiate happiness. His giggles and endless smiles made every day a joy for them. Strangers in the supermarket often remarked on how cheerful he seemed, making Meera and Raj proud of their bubbly little boy. One day, while grocery shopping, they bumped into Dr. Gupta, an old acquaintance who happened to be a pediatrician.

Dr. Gupta admired Aarav's bright smiles but seemed to study him a bit too intently. Politely, she asked if they had noticed any other unusual behavior.

Raj and Meera were taken aback when Dr. Gupta gently suggested they visit a doctor, not out of concern for Aarav’s happiness, but because she had noticed something off about his behavior. Dr. Gupta made it clear that she didn’t want to worry them, but from her medical perspective, Aarav’s constant, almost involuntary smiling could be more than just happiness. "Sometimes, things aren't what they seem," she said kindly, "and it wouldn’t hurt to rule out any underlying issues, just to be safe."

Despite their initial shock and fear, Meera and Raj took her advice seriously. Little did they know that Dr. Gupta’s careful observation would lead to a life-changing diagnosis. Aarav was eventually diagnosed with a benign brain tumor, which had been affecting certain parts of his brain responsible for facial expressions. Though it was a difficult journey, catching the tumor early helped them get Aarav the care he needed. Raj and Meera learned the importance of trusting their instincts but also listening when a medical professional raises a red flag, no matter how subtle it may seem.

Pediatric Brain Tumors: What Every Parent Should Know

Pediatric brain tumors are abnormal growths of cells that begin in or around the brain in children. These growths, called tumors, can press on nearby areas of the brain, which can lead to a range of symptoms, including headaches, nausea, and in some cases, more subtle changes like irritability or vision problems. While any brain tumor diagnosis can be overwhelming, it’s important for parents to understand the different types of brain tumors and the treatment options available for their children.

Brain tumors in children vary widely in terms of growth rate and severity. Some tumors are fast-growing and aggressive, while others grow slowly over time. Tumors can also be classified as cancerous (malignant) or noncancerous (benign). However, it’s important to note that even benign tumors can cause significant health issues if they grow large enough or are located in sensitive areas of the brain.

The type of brain tumor, along with its location and whether it has spread beyond the brain, plays a key role in determining the best treatment plan for a child.

Other factors that healthcare providers consider when planning treatment include the child’s age, overall health, and the size of the tumor. Pediatric brain tumors require specialized care, as the treatments for children are often different from those used for adults. This is why it’s essential to seek medical advice from a center that has experience treating pediatric brain tumors, where the team will be better equipped to manage the unique needs of children.

Signs and Symptoms of Pediatric Brain Tumor

The signs and symptoms of pediatric brain tumors can vary depending on the size and location of the tumor, as well as how quickly the tumor is growing. Some common signs to watch for include frequent headaches, which may become progressively worse. For children who are too young to communicate, parents might notice increased irritability as a sign of discomfort. Another common symptom is nausea and vomiting, which can occur without any other signs of illness.

Vision problems are also a red flag. Children may develop double vision or other changes in how they see. Non-verbal children may squint, rub their eyes frequently, or even cover one eye when trying to focus on something. Other symptoms include balance problems, confusion, and changes in personality or behavior. Parents may also notice their child struggling to walk, slurring their speech, or having trouble swallowing.

In babies, signs of a brain tumor can be even more subtle. A fuller-than-usual soft spot on the head or abnormal eye movements can be early indicators. Seizures, especially if they occur in a child who has never had one before, should also prompt immediate medical attention.

When to Seek Medical Help

It’s important for parents to act promptly if they observe any of the warning signs of a brain tumor. Symptoms like frequent headaches, vomiting, vision changes, or unexplained irritability should not be ignored. If a child is showing any of these symptoms, parents should make an appointment with their pediatrician or another healthcare provider. Early detection and treatment can make a significant difference in a child’s prognosis and quality of life.

While the idea of a brain tumor is frightening, it’s important to remember that treatment options have advanced significantly. With early diagnosis and a personalized treatment plan, many children with brain tumors can lead full and healthy lives.

As parents, it’s crucial to stay informed and attentive to any changes in your child’s health, as early intervention is key in managing pediatric brain tumors effectively.

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Two Year Old Girl Diagnosed With Childhood Dementia

Updated Mar 24, 2026 | 01:02 PM IST

SummaryLeni, 2, diagnosed with Sanfilippo Syndrome Type B, a rare childhood dementia, faces progressive cognitive and physical decline without treatment. Her parents are raising funds, seeking trial access, and urging early screening and investment.
Two Year Old Girl Diagnosed With Childhood Dementia

Credits: GoFundMe

For most parents, the toddler years are filled with first words, wobbly steps and dreams of the future. For Gus and Emily Forrester, those moments are now overshadowed by a diagnosis they describe as “every parent’s worst nightmare.”

Their two-year-old daughter, Leni, has been diagnosed with Sanfilippo Syndrome Type B, a rare genetic condition often referred to as childhood dementia. The disorder, formally known as Mucopolysaccharidosis type III, gradually robs children of their physical and cognitive abilities.

In an interview with ITV News, Leni’s parents spoke about the devastating reality of the condition, which has no approved cure or widely available treatment.

“All your dreams for your child's future are taken away,” her mother, Emily, said. “To be told that she has this condition, and there is no treatment and no cure and no support… it’s completely earth-shattering.”

What Is Childhood Dementia?

Two Year Old Girl Diagnosed With Childhood Dementia

Sanfilippo Syndrome is a neurodegenerative disorder caused by the body’s inability to break down certain complex sugars. Over time, these substances build up in the brain, leading to progressive damage.

According to Cure Sanfilippo Foundation, symptoms usually begin appearing between the ages of one and six. Children may initially show mild developmental delays, but the disease gradually worsens, affecting speech, mobility and behaviour.

As the condition advances, many children lose the ability to talk, walk and recognise loved ones. Life expectancy is often limited to the early teenage years.

Emily explained the process in stark terms. Without treatment, she said, Leni’s body will slowly be overwhelmed by “toxic waste,” causing irreversible damage.

The Urgency of Early Treatment

For families like the Forresters, time is not just precious, it is critical.

“Early treatment is key for these children,” Emily said. “If she has to wait six months, that could mean she can no longer talk. If she waits 12 months, that could mean she loses the ability to walk.”

Although experimental therapies, including gene-based approaches, are being developed, access remains a major hurdle. Some clinical trials are expected to take place in the United States later this year, but Leni is not currently eligible.

Her parents are now campaigning for UK patients to be included in these trials, arguing that promising science already exists but remains out of reach for many families.

A Family's Fight For Hope

In response to the diagnosis, the Forresters have launched a fundraiser to support Leni’s care and potential treatment options. They have also pledged to donate part of the funds to Great Ormond Street Hospital, where Leni is receiving care, and to the Cure Sanfilippo Foundation, which supports affected families.

So far, donations have crossed $250,000, reflecting the growing awareness and concern around rare childhood conditions.

Leni’s father, Gus, said the emotional toll of the diagnosis is hard to put into words. “As parents, your role is to protect your children and provide every opportunity you can. Without any treatment, her future and her reality is very, very dark.”

Beyond fundraising, the couple is also raising awareness about childhood dementia and advocating for newborn screening programmes that could help detect such conditions earlier.

Experts working on experimental therapies say greater government investment is urgently needed. Without it, many children may never benefit from treatments that could slow or alter the course of the disease.

For now, Leni remains a cheerful two-year-old, full of life and affection. But for her parents, every passing day is a reminder of how quickly that could change, and how urgently answers are needed.

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Is Cough Really Necessary For TB? 80% Of Patients Don't Have It, Says Study

Updated Mar 24, 2026 | 01:37 PM IST

SummaryOn World Tuberculosis Day, experts warned Tuberculosis in India remains high, with many cases lacking persistent cough, delaying diagnosis. New initiatives aim to improve detection, treatment and support elimination efforts by 2025.
Is Cough Really Necessary For TB? 80% Of Patients Don't Have It, Says Study

Every year, March 24 is observed as World Tuberculosis Day to spread awareness about the infectious disease. In India, it remains one of the most pressing infectious diseases. Dr Arup Halder, Consultant Pomologist at CK Birla Hospitals, CMRI says that India still accounts for roughly a quarter to over a quarter of world's tuberculosis or TB cases. "In 2023–2024, India reported around 25–26 lakh TB patients out of an estimated 27 lakh cases, reflecting improved detection but also highlighting a persistently high burden," he points out.

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While TB incidence has fallen by about 20 per cent since 2015 and mortality has also declined to roughly 21 deaths per lakh population, it still remains well above national elimination targets for 2025.

TB Could Happen Even Without A Persistent Cough

What makes TB so difficult to eliminate? While many associate TB with persistent coughing, studies show that 80 per cent of patients do not show the symptoms of cough that is "presumed" to be a common symptom. This is why, TB could go ignored until it is too late.

A research led by Amsterdam UMC and the Amsterdam Institute for Global Health and Development analyzed data on more than 600,000 individuals in Africa and Asia and found that around 82.8 per cent of those with TB had no persistent cough. The study also found that 62.5 per cent had no cough at all. The findings were published in the Lancet Infectious Diseases.

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The study in fact noted that this could be the "probable reason why, despite huge efforts to diagnose and treat the disease, the tb burden across Africa and Asia is hardly declining". Frank Cobelens, Professor of Global Health at Amsterdam UMC and Senior Fellow at the AIGHD says, "A persistent cough is often the entry point for a diagnosis, but if 80 per cent of those with TB do not have one, then it means that a diagnosis will happen later, possibly after the infection has already been transmitted to many others, or not at all."

Another 2019 study published in Elsevier notes: "Coughing does not appear to be a necessary prerequisite for TB transmission." The study further mentions, "Frequency of cough is associated with infectivity but this does not imply mechanistic causality for TB transmission."

Does It Mean Coughing Is Harmless?

The simple answer to this is: No. Coughing does not mean harmless, especially when it is a persistent one. The study only shows that TB does not always mean persistent coughing, however, if one experiences this symptom, they should always get a test done and should not ignore the symptoms.

Researchers from The University of Texas at Dallas' Center for Advanced Pain Studies working with colleagues from UT Southwestern Medical Center note that TB coughing could cause pain. This is one of the way one can distinguish the symptoms. The findings published in journal Cell notes that before this study, "no one had even shown that TB produces an irritant that acts directly on the sensory innervation of the lungs".

Corresponding author Dr Michael Shiloh, associate professor of internal medicine and microbiology at UT Southwestern said, "People with active tuberculosis can cough for months and spread disease even when they are receiving appropriate treatment."

Read: World Tuberculosis Day 2026: Theme, Origin, And Significance

What Is India Doing To Control TB Cases?

On World TB Day, President Droupadi Murmu stressed that TB continues to pose a significant public health challenge and has affected millions of lives across the world. She urged all stakeholders to work together with collective resolve to end TB once for all.

To act on it, Union Health Minister Jagat Prakash Nadda will launch a series of initiatives, including 'TB Mukt Bharat Abhiyaan - 100 Days Campaign', the TB Mukt Bharat App, and the TB Mukt Urban Ward Initiative. These measures are designed to strengthen the case detection, improve treatment adherence, and enhance last-mile delivery of TB services, especially in high-burden areas. The initiatives have also been aligned with the objectives of the National Tuberculosis Elimination Programme.

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Bacterial Meningitis May Cause Long-term Fatigue, Vision Problems, Raise Suicide Risk: Study

Updated Mar 24, 2026 | 03:00 AM IST

SummaryThe long-term effects of the deadly bacterial meningitis among survivors include fatigue, difficulties with concentration, memory and emotional regulation, persistent headaches, issues with mobility, vision, and hearing.
Bacterial Meningitis May Cause Long-term Fatigue, Vision Problems, Raise Suicide Risk: Study

Credit: Canva

From physical problems like fatigue and vision problems, people who survive the deadly bacterial meningitis are likely to live with long-term fatigue and vision problems, as well as be at high risk of suicide, according to a new study.

The study comes as the UK is experiencing an outbreak of meningitis in Kent, that began among students who visited Club Chemistry in Canterbury between March 5 and 7.

Although bacterial meningitis is treatable, it requires prompt, often immediate treatment for better recovery. Yet patients are likely to face the risk of fatal or long-term complications -- from physical, psychological, and social impacts, said researchers from the University of Otago, The Conversation reported.

The new findings, based on 16 cases from New Zealand, who reportedly suffered the fatal disease, showed that multiple chronic after-effects is permanent in some, while in others, it dragged on for years. The effects include:

  • fatigue,
  • difficulties with concentration,
  • memory and emotional regulation,
  • persistent headaches,
  • issues with mobility, vision, and hearing.
These conditions affected the patients' ability to work, study, and maintain relationships, which further affected their mental health, increasing their vulnerability for

  • anxiety,
  • depression
  • suicidality.

"Our findings demonstrate that bacterial meningitis is much more than a life-threatening infection. It is an acute disease with serious, chronic after-effects which are poorly understood and often go unrecognised," the researchers said.

Kent Meningitis Outbreak

According to the latest update from the UK Health Security Agency (HSA), 20 laboratory cases of meningitis are confirmed, and 9 notifications remain under investigation, bringing the total to 29 in the country.

The bug that causes the infection has been identified as the known strain of meningitis B, and MenB vaccines will be offered to 5,000 students living in the University of Kent halls of residence in Canterbury.

Meanwhile, the UKHSA chief executive, Susan Hopkins, said the outbreak "looks like a super-spreader" event with "ongoing spread" through universities' halls of residence.

"There will have been some parties, particularly around this, so there will have been lots of social mixing. I can't yet say where the initial infection came from, how it's got into this cohort, and why it's created such an explosive amount of infections," she added.

As per Trish Mannes, UKHSA Regional Deputy Director for the South East, even after two doses, the MenB vaccine “does not protect against all strains of meningococcal disease, nor against all infections that can cause meningitis. It also does not prevent the bacteria from being carried and spread in the community”.

The UKHSA thus warned people to be aware of the signs and symptoms of invasive meningococcal disease, and to seek immediate medical attention if they or anyone they know develops these signs and symptoms.

Common symptoms include:

  • rash
  • sudden onset of high fever
  • severe and worsening headache
  • vomiting and diarrhea
  • joint and muscle pain
  • seizures.

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