As COVID and viral infections cases rise in numbers, researchers are finding out how, following the bout of cases, the risk of heart diseases has also increased in people. To explore this connection, new research published today in the Journal of the American Heart Association reveals a strong link between both acute and chronic viral infections and an increased risk of serious cardiovascular events, such as heart attacks and strokes. The lead author, Dr. Kosuke Kawai, noted that while we know viruses can cause cancer, their link to non-infectious diseases like heart disease hasn't been clear. This study confirms that acute (short-term) and chronic (long-term) viral infections are connected to both immediate and lasting risks for heart and brain events. How Do Short Infections Cause Harm To Heart? When your body fights off a virus, your immune system releases chemicals that cause inflammation (swelling) and make your blood more likely to clot. Both of these problems can linger even after the virus is gone. This ongoing inflammation and tendency to clot can damage the heart and blood vessels, which is likely why the risk of a heart attack or stroke spikes so dramatically right after an illness. The research details what happens to your heart risk right after you get a respiratory infection. The study combined data from many high-quality reports and found a major, temporary jump in risk: Influenza (Flu) In the month immediately following a confirmed flu infection, people were 4 times more likely to have a heart attack and 5 times more likely to have a stroke compared to when they weren't sick. COVID-19 After a COVID infection, the risk was also high. People were 3 times more likely to have a heart attack and 3 times more likely to have a stroke in the first 14 weeks. Worryingly, this risk stayed higher than normal for an entire year. What Infections Cause Long-Term Heart Risk? This part of the study focused on people who have had certain chronic (long-lasting) viral infections, tracking their health for an average of over five years to see if their risk remained high: HIV Infection People with HIV had a 60% higher risk of heart attack and a 45% higher risk of stroke. Hepatitis C This infection was linked to a 27% higher risk of heart attack and a 23% higher risk of stroke. Shingles (Herpes Zoster) Even this common virus was associated with a 12% higher risk of heart attack and an 18% higher risk of stroke. Even though these percentage increases are smaller than the immediate post-flu/COVID jump, they are still very important because the risk lasts for years. Shingles, for example, affects about one in three people in their lifetime, meaning that this seemingly small increase in risk will lead to a large number of extra heart problems across the general population over time. How Can We Prevent Risk Of Heart Attacks After Infections? The study suggests a powerful way to fight these risks is by getting vaccinated. The findings strongly support the idea that increasing the number of people who get flu, COVID, and shingles shots could lower the overall rate of heart attacks and strokes in the community. As an example, previous research has shown that getting a flu shot can be linked to a 34% lower risk of major heart problems. The American Heart Association recommends that everyone, especially those with existing heart conditions or heart risk factors, talk to their doctor about getting the right vaccines. Vaccination is a simple step that offers crucial protection to people whose hearts are already vulnerable. It’s important to remember that this study was based on looking at people's health records (observational studies), not on controlled experiments. The main focus was on single viruses. Researchers noted that we still need more studies to fully understand how some other viruses, like dengue and HPV, might be linked to heart disease.