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Rachel V Thomas

India Launches 1st Repository Of Data On Major Psychiatric Disorders

About 10.6 percent –15 percent of India's population suffers from some form of mental health conditions, with 15 percent of the adult population also requiring active intervention.

To enable researchers to gather as well as systematically document data on patients with major forms of mental illness, neuroscientists in India have developed CALM-Brain — a digital repository of data on brain structure and function from a range of psychiatric disorders.

CALM-Brain contains data from over 2,000 participants from 900 families across the country. 

CALM-Brain will help clinicians and researchers 

<ul><li>to understand the onset of neuropsychiatric disease </li><li>check progression </li><li>decode underlying biological changes </li><li>provide better diagnosis </li><li>plan personalized treatments for patients.</li></ul>

“CALM-Brain was conceived as a method to assemble data from multiple scales of analysis of brain structure and function on a single platform. We believe that the application of modern methods of data analysis to this dataset will help bridge the gap between these scales of analysis,” said Prof. Raghu Padinjat, CBM co-ordinator at CBM-NCBS, in a statement.

Also read: <a href="https://www.healthandme.com/health-wellness/world-happiness-report-2026-flags-social-media-harms-on-adolescents-mental-well-being-article-153873115" data-type="tilCustomLink">World Happiness Report 2026 Flags Social Media Harms On Adolescents' Mental Well-being</a>

CALM-Brain is the result of collaborative efforts of researchers at the Rohini Nilekani Centre for Brain and Mind (CBM) — a partnership between the National Institute of Mental Health and Neuro Sciences (NIMHANS) and the National Centre for Biological Sciences (NCBS) - TIFR.

CALM-Brain is India’s first-of-its-kind repository of clinical, neuroimaging, behavioral, genetic, and other datasets on disorders such as: 

<ul><li>addiction, </li><li>bipolar disorder, </li><li>dementia, </li><li>obsessive compulsive disorder (OCD) </li><li>schizophrenia.</li></ul>This longitudinal data incorporates multiple modes of studying brain function in neuropsychiatric diseases:

<ul><li>Functional Magnetic Resonance Imaging (fMRI) </li><li>Near Infrared Spectroscopy (NIRS) </li><li>electroencephalogram (EEG) </li><li>observations of cognition </li><li>eye-tracking </li><li>genetic analyses of blood samples </li><li>clinical assessments.</li></ul>

The dataset is also linked to a biorepository of stem cells, which can be used to perform biological research in psychiatry to understand the origins of such severe mental illnesses. 

“The primary goals of the project are to identify biological markers of severe psychiatric illnesses, which cut across traditional diagnostic frameworks. In addition, we will try to identify fundamental biological mechanisms of the disease and medication response,” said Prof. Y.C. Janardhan Reddy, CBM coordinator at CBM-NIMHANS. 

<h2>Burden Of Mental Illnesses In India </h2>

Mental wellness is a major health and economic concern in India. The World Health Organization (WHO) estimates India’s economic loss due to mental health conditions to be USD 1.03 trillion (2012-2030). 

Recently, health experts and policymakers, as part of the government-led Post-Budget Webinar series, highlighted the growing burden of mental and neurological disorders in India and also stressed the urgent need to strengthen institutional capacity to meet emerging healthcare demands. 

"<a href="https://www.healthandme.com/health-news/1-in-7-indians-affected-by-mental-health-disorders-govt-to-launch-nimhans-2-to-boost-care-article-153793857" data-type="tilCustomLink">One in seven Indians</a> is affected by mental health disorders, while several states continue to face a treatment gap ranging from 70 to 90 percent," the experts said.

They added that "neurological and mental health conditions are among the leading contributors to disability-adjusted life years (DALYs)" among citizens. 

To address the rising burden, the government aims to launch NIMHANS-2 — first announced by Finance Minister Nirmala Sitharaman during the Union Budget 2026-27 — to deliver specialized care for mental health and neurological disorders in north India.

"In addition, the Central Institute of Psychiatry, Ranchi, and the Lokopriya Gopinath Bordoloi Regional Institute of Mental Health, Tezpur, will be upgraded as regional apex institutions to strengthen mental healthcare services in the eastern and north-eastern regions," FM Sitharaman said.

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About 10.6 percent –15 percent of India's population suffers from some form of mental health conditions, with 15 percent of the adult population also requiring active intervention. To enable researchers to gather as well as systematically document data on patients with major forms of mental illness, neuroscientists in India have developed CALM-Brain — a digital repository of data on brain structure and function from a range of psychiatric disorders. CALM-Brain contains data from over 2,000 participants from 900 families across the country. CALM-Brain will help clinicians and researchers to understand the onset of neuropsychiatric disease check progression decode underlying biological changes provide better diagnosis plan personalized treatments for patients.“CALM-Brain was conceived as a method to assemble data from multiple scales of analysis of brain structure and function on a single platform. We believe that the application of modern methods of data analysis to this dataset will help bridge the gap between these scales of analysis,” said Prof. Raghu Padinjat, CBM co-ordinator at CBM-NCBS, in a statement. Also read: World Happiness Report 2026 Flags Social Media Harms On Adolescents' Mental Well-beingWhat Is CALM-Brain? CALM-Brain is the result of collaborative efforts of researchers at the Rohini Nilekani Centre for Brain and Mind (CBM) — a partnership between the National Institute of Mental Health and Neuro Sciences (NIMHANS) and the National Centre for Biological Sciences (NCBS) - TIFR. CALM-Brain is India’s first-of-its-kind repository of clinical, neuroimaging, behavioral, genetic, and other datasets on disorders such as: addiction, bipolar disorder, dementia, obsessive compulsive disorder (OCD) schizophrenia.This longitudinal data incorporates multiple modes of studying brain function in neuropsychiatric diseases: Functional Magnetic Resonance Imaging (fMRI) Near Infrared Spectroscopy (NIRS) electroencephalogram (EEG) observations of cognition eye-tracking genetic analyses of blood samples clinical assessments.The dataset is also linked to a biorepository of stem cells, which can be used to perform biological research in psychiatry to understand the origins of such severe mental illnesses. “The primary goals of the project are to identify biological markers of severe psychiatric illnesses, which cut across traditional diagnostic frameworks. In addition, we will try to identify fundamental biological mechanisms of the disease and medication response,” said Prof. Y.C. Janardhan Reddy, CBM coordinator at CBM-NIMHANS. Burden Of Mental Illnesses In India Mental wellness is a major health and economic concern in India. The World Health Organization (WHO) estimates India’s economic loss due to mental health conditions to be USD 1.03 trillion (2012-2030). Recently, health experts and policymakers, as part of the government-led Post-Budget Webinar series, highlighted the growing burden of mental and neurological disorders in India and also stressed the urgent need to strengthen institutional capacity to meet emerging healthcare demands.  "One in seven Indians is affected by mental health disorders, while several states continue to face a treatment gap ranging from 70 to 90 percent," the experts said.  They added that "neurological and mental health conditions are among the leading contributors to disability-adjusted life years (DALYs)" among citizens.  To address the rising burden, the government aims to launch NIMHANS-2 — first announced by Finance Minister Nirmala Sitharaman during the Union Budget 2026-27 — to deliver specialized care for mental health and neurological disorders in north India.  "In addition, the Central Institute of Psychiatry, Ranchi, and the Lokopriya Gopinath Bordoloi Regional Institute of Mental Health, Tezpur, will be upgraded as regional apex institutions to strengthen mental healthcare services in the eastern and north-eastern regions," FM Sitharaman said.

india launches 1st repository of data on major psychiatric disorders

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India Launches 1st Repository Of Data On Major Psychiatric Disorders

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India Launches 1st Repository Of Data On Major Psychiatric Disorders

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