Image Credit: Canva
Aging is an inevitable journey undertaken by all, but the quality varies greatly between individuals. The number of years lived describes longevity, but healthspan is the years spent in good health, which must be considered as the true measure of life. Advances in medicine extend our lifespan, though they rarely ensure that added years are lived free from disease or disability.
Recent studies emphasize that lifestyle choices, environmental factors, and mental health far outweigh genetics in influencing healthspan and longevity.
Mental health encompasses emotional, psychological, and social well-being to determine overall health. Mental health is defined by the WHO as a state wherein persons can realize their skills to cope with normal situations that life throws at them while working productively within one's community. That emphasizes how mental health isn't just the absence of disease but a positive active process of thriving.
The connection between mental health and longevity is profound and multifaceted. Stress management, optimism, purpose, and engagement in mentally stimulating activities are strong contributors to enhancing healthspan. These factors influence biological processes like mitochondrial function, telomere length, cellular health, and proteostasis, all hallmarks of aging.
Also Read: The Blue Zones: What We Can Learn from the World’s Longest-Lived People
Mental exercise is to the brain what exercise is to the body. Activities like reading, solving puzzles, learning a new language, or mastering a skill keep cognitive decline at bay. A 2013 study found that adults who regularly engage in intellectually challenging activities experience slower rates of dementia and other cognitive impairments.
Moreover, mental involvement creates a healthy balance in the neurochemical environment of the brain, reducing risks of depression and improving the overall mood. This mental strengthening directly contributes to a longer and more fulfilling life.
Loneliness is often described as the new smoking in terms of health risks. It's a huge barrier to aging well. Social isolation has been associated with higher risks of chronic diseases, depression, and even premature death. Strong social bonds and meaningful relationships, on the other hand, improve emotional well-being, lower stress, and even boost immune function.
Engagements and meetings of friends and family, group associations, or even staying connected with the loved ones offer emotional support, stress-reduction, and a feeling of belonging-all essential requirements for long and healthy living.
These factors in the biological foundation of aging, which include mitochondrial dysfunction, telomere shortening, and cellular senescence, can be impacted by mental health. Chronic stress accelerates these processes due to higher oxidative stress and systemic inflammation. For example, an important study done in 2004 proved that chronic levels of perceived stress had shortened telomeres-that is, protective caps of chromosomes-by a decade equivalent.
The "inflammaging" is also part of the contribution of inflammation induced by stress, representing chronic low-grade inflammation underlying many age-related diseases. Thus, with proper stress management and good mental health, these deleterious effects can be mitigated, protecting cellular health and increasing healthspan.
Practicing gratitude and mindfulness can transform the aging experience. Gratitude shifts focus from what is lacking to what is abundant, fostering joy and contentment. Keeping a gratitude journal or simply reflecting on the positives can create a lasting sense of well-being.
Mindfulness grounds the individual in the present moment, thus not allowing him to worry about the future or grieve over what has been. Mindfulness, therefore, is the practice of meditation or mindful walking, which can make a person feel calm and centered, leading to greater emotional and physical resilience.
This process is less about reversing time and more about embracing it with energy and grace. Mental health is the foundation of this journey, which not only determines how long we live but also how well we live. Adopting relaxation techniques, cultivating optimism, engaging in mental stimulation, nurturing social connections, and embracing gratitude and mindfulness help unlock the secrets to a longer, healthier life.
Chronic stress contributes silently to aging, enhancing damage at cellular levels and exacerbating inflammatory processes. Oxidative stress and inflammation have also been significantly diminished by means of relaxation, such as meditation, yoga, or deep breathing exercises. Routine use of such practices may benefit not only mental conditions but also contribute to enhancing health at a physical level through lowering of blood pressure, improvement of immune activity, and stability of emotions.
Stress, unless controlled, can worsen conditions associated with aging, including cardiovascular disease, diabetes, and neurodegeneration. A 2015 report showed that those who implemented stress-reducing interventions had improved mitochondrial function, which in turn reduced chronic disease risk. By promoting relaxation, one is working directly against the biological impact of aging.
A positive attitude toward life is not just uplifting; it is life-extending. Optimistic people have less cortisol in their systems, better immune responses, and healthier lifestyles. Equally important is the cultivation of a sense of purpose. Whether it is through career achievements, volunteering, or personal hobbies, having something to get up for fuels emotional resilience and physical vitality.
(Credit- Canva)
One of the first impressions we make is from a person’s oral hygiene. How clean their teeth look, if they have any mouth odor, how they eat etc. However, did you know, that your mouth health could also make your heart diseases worse? Could they be the actual reason behind what triggered your heart disease?
New research suggests that the health of your mouth might be connected to the health of your heart. A study found that the fatty clogs in our arteries, known as plaques, often contain bacteria. This hints that a slow, ongoing inflammation caused by these bacteria and our body's reaction to them could be a major factor in heart disease.
According to the American Heart Association, the germs from your mouth can affect your heart? The same bacteria that cause tooth decay and gum disease can travel to other parts of your body, including your heart, potentially leading to serious health problems.
Plaques are a buildup of fatty stuff inside your arteries, and this is a long-term problem caused by inflammation. For a long time, doctors have wondered if infections play a role in this process. While early studies were promising, giving antibiotics to people with heart disease didn't seem to help much.
This new study proposes a different idea: maybe certain bacteria form a protective "biofilm" inside the plaques, where they sit quietly and cause a low-level inflammation. This biofilm might hide the bacteria from our immune system and make them resistant to antibiotics. Over time, this quiet infection could turn a stable plaque into a dangerous one that could rupture and cause a heart attack.
A type of bacteria called viridans streptococci has been found in these plaques. These bacteria normally live in our mouths and are involved in forming dental plaque. They often get into the bloodstream during dental procedures. The study found that:
The research showed that these bacteria weren't just passing through the arteries; they were setting up a little community—a biofilm—inside the plaques. This biofilm acted like a shield, protecting the bacteria from our immune system.
But when a plaque breaks open, which is what causes a heart attack, the bacteria inside the biofilm get out. This triggers a huge immune response that can weaken the plaque's outer layer, leading to a blood clot that blocks blood flow to the heart.
The study concludes that these mouth bacteria are not harmless. Instead, a hidden, long-term bacterial infection in the form of a dormant biofilm may be what turns a stable plaque into a dangerous one. This finding highlights how important inflammation is in heart disease and could lead to new ways to diagnose and prevent it in the future.
(Credit- Canva)
Hair is one of the key aspects of a person’s look. A simple haircut can completely change the way you look. So, you can imagine how losing one’s hair can affect them. While it happens to many people, it can completely change the way they view themselves. Although it is a normal part of aging, many men face this challenge from a young age due to many reasons like genetics, male-patterned baldness etc.
While there are ways you can tackle major hair loss like hair transplant, not everyone can afford it. However, a new drug called PP405 might be a game-changer for baldness. Instead of just slowing down hair loss, this new topical drug actually helps "wake up" your hair follicles that have gone to sleep. In early tests, it showed promising results, making hair thicker for some people who used it. If this treatment works in bigger trials, it could be a whole new way to fight baldness.
The new drug, PP405, is a topical cream that you apply to the scalp. It's different from older treatments because it doesn't just try to slow down hair loss. Instead, it works by waking up the hair follicles that have become dormant, or "asleep." Scientists found that in many people with hair loss, the stem cells in their hair follicles aren't dead—they've just stopped working. This new drug specifically targets these dormant cells to get them growing hair again.
In an early study, led by dermatologist Qing Yu Christina Weng, MD, chief medical officer of Pelage Pharmaceuticals, the results were very promising: some patients saw their hair become more than 20% thicker. The new hair wasn't just thin, "baby hair"; it was thick, mature hair. A key safety feature is that the drug is designed to get into the skin where it's needed without being absorbed into the rest of the body.
Dermatologists are excited about the new drug's potential because it offers a completely new way to treat hair loss. However, they are also being cautious. The study so far was small and short, and the results haven't been fully checked by other scientists yet. The drug still needs to go through much larger studies, which could take a few years.
Right now, the only FDA-approved treatments for hair loss are finasteride and a topical solution called minoxidil. While doctors sometimes use an oral version of minoxidil, these treatments don't work for everyone, especially for those with severe hair loss. This leaves many people with limited options, often turning to expensive and unproven treatments like special injections or lasers.
If PP405 passes its larger trials, it could be a huge breakthrough. It would be the first new FDA-approved hair loss treatment in over 25 years. This could be especially helpful for people who have more severe hair loss and haven't had success with other medications.
The researchers also believe this drug might one day be used to treat other types of hair loss, such as hair thinning caused by certain medications or hormonal changes. However, experts say that before the drug is used for other conditions, it must be thoroughly tested in larger groups of people to prove it is safe and effective.
Credits: Health and me
Your skincare shelf might be quietly sabotaging your glow—and you don’t even know it. Think about it: the same cream you swipe on at 7 a.m. is also applied at 11 p.m. But your skin isn’t static; it’s a living, breathing organ with different priorities depending on the time of day. Morning skin is on defense, battling sunlight, pollution, and blue light, while nighttime skin is in repair mode, regenerating and replenishing. Using the same products both times may be convenient, but convenience could come at the cost of healthier, radiant skin.
Skincare seems simple on the surface—wash, moisturize, repeat. Many of us follow the same routine morning and night, believing that if a product works once, it works all day. But according to dermatologist Dr. Vikram Lahoria, this approach may be doing more harm than good. Your skin operates on a circadian rhythm, and the way it behaves during the day differs significantly from its nighttime activities. Understanding these differences—and adjusting your routine accordingly can be the difference between healthy, glowing skin and clogged pores, premature aging, or irritation.
Dr. Lahoria explains, “During the day, your skin is exposed to sunlight, pollution, dust, and even the blue light from screens. Its main role is protection. That’s why your morning routine should focus on creating a barrier against these environmental stressors.”
A typical morning routine starts with a gentle cleanser to remove oils and sweat accumulated overnight. This is followed by a light, hydrating moisturizer that won’t feel greasy or clog pores. The most crucial step in your AM routine is sunscreen. No matter the weather, SPF shields your skin from UV rays, reducing the risk of premature aging, pigmentation, and even skin cancer.
Adding an antioxidant serum, particularly one with vitamin C, can further protect against free radicals generated by pollution and UV exposure. “Think of it as giving your skin armor before stepping into the world,” says Dr. Lahoria.
Once the sun sets and the day winds down, your skin switches gears. “Nighttime is when your skin works hardest to repair itself,” Dr. Lahoria notes. Without sunlight and environmental stressors, skin cells can focus on regeneration and replenishment.
Night creams and serums are designed to support this process. Ingredients like retinol, peptides, hyaluronic acid, and glycolic acid target fine lines, improve texture, and lock in moisture. A thorough cleanse is essential before applying these products to remove makeup, sweat, and dirt that could block pores overnight.
“Nighttime is when your skin absorbs products most efficiently. The lack of UV exposure means potent actives like retinol can work without the risk of sun-induced irritation,” explains Dr. Lahoria.
Using identical products morning and night ignores the skin’s shifting priorities. “It’s like feeding your body the same meal for breakfast and dinner,” says Dr. Lahoria. “In the morning, your skin needs protection. At night, it needs repair. One product cannot optimally serve both functions.”
Daytime exposure to retinoids or AHAs, for instance, can increase sensitivity to sunlight, potentially causing irritation, pigmentation, or damage. Conversely, using sunscreen at night is unnecessary, and while it won’t harm your skin, it doesn’t contribute to repair either. Tailoring your routine ensures that ingredients work when they are most effective, rather than canceling each other out or creating unintended side effects.
Timing is not the only consideration—the order in which you apply your skincare products matters too. Dr. Lahoria advises layering from thinnest to thickest. This ensures lightweight serums penetrate deeply before being sealed in by heavier creams or oils. Incorrect layering can hinder absorption or even reduce the efficacy of active ingredients.
For example, a vitamin C serum should be applied before moisturizer, while a heavier night cream should go last. By following this approach, each product can work as intended, maximizing benefits without waste or interference.
Your skin, like your body, has a circadian rhythm. During the day, its priority is defense; at night, it focuses on repair. “Ever wonder why your skin behaves differently in the morning than it does at night? That’s your internal clock at work,” Dr. Lahoria points out.
Adjusting your routine according to this natural rhythm ensures your skin gets the right nutrients at the right time. In the morning, protect; at night, repair. Over time, this approach improves skin health, prevents premature aging, and enhances the results from the products you invest in.
Dr. Lahoria summarizes an effective framework:
Morning:
Night:
Following these guidelines ensures that your skin is supported according to its natural needs, rather than treated with a one-size-fits-all approach.
Skincare is not just about selecting the “right” products—it’s also about using them at the right time. Dr. Lahoria concludes, “Your morning and evening routines should act like a tag team. Each plays its role in protecting, repairing, and energizing your skin. Your clock isn’t just ticking, it’s guiding your glow.”
By understanding your skin’s natural cycles, choosing the right ingredients for day and night, and applying them in the correct order, you ensure your skin remains healthy, radiant, and resilient—without unnecessary irritation or damage.
Dr. Vikram Lahoria is a consultant dermatologist and medical advisor at Ceuticoz in India
© 2024 Bennett, Coleman & Company Limited