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Danish pharmaceutical giant Novo Nordisk scored a huge legal victory that restricts compounding pharmacies from marketing or selling cheaper, unapproved versions of its blockbuster weight loss drugs Ozempic and Wegovy. On Monday, US District Judge Mark Pittman denied the Outsourcing Facilities Association's bid for a preliminary injunction that would have prevented the FDA from taking action against its members for making copies of semaglutide, the active ingredient in Ozempic and Wegovy.
Compounding is a process where pharmacies mix ingredients of a drug to create a specialised version for specific patients. Say someone is allergic to a dye in a branded medication or needs a liquid form, and the main manufacturer only sells capsules. In that case, the patient can turn to a compounded version or the liquid form. Moreover, when drugs are in short supply, they can be compounded in larger quantities to help fill the gap.
Hundreds of thousands of people flocked to these compounding firms when they didn't have enough money to afford the costly weight loss treatments. The prices of both Wegovy and Ozempic rose exponentially, given the skyrocketing demand in the last two years. Notably, the Texas judge's verdict came in response to a February lawsuit from a compounding trade group against the FDA's determination that the active ingredient in those drugs, semaglutide, is no longer in shortage in the US. The decision also means the FDA can start targeting federally regulated 503B pharmacies, which manufacture compounded drugs in bulk with or without prescriptions, after May 22. The agency’s actions can include product seizures and warning letters to pharmacies.
Semglutide is the synthetic version of GLP-1, a natural hormone produced in the intestines that regulates blood sugar, appetite, and digestion. Now, every time you eat, your body produces various hormones, including GLP-1. These are called post-nutrition hormones and help you absorb the energy you just consumed.
GLP-1 travels to your pancreas, prompting it to produce insulin. It also travels to the hypothalamus in your brain, which gives you the feeling of being full or satiated. Ozempic imitates this hormone, thereby silencing the food chatter in the brain. Interestingly, for some people this food chatter is really quiet ( people with low appetite), and for others, it is an outburst (people who generally binge eat.) So with Ozempic, silencing this self-talk in the brain, people tend to lose their appetite and eventually weight.
However, it is important to note that losing weight includes not just fat but muscle as well. Losing too much muscle can lead to reduced strength and a shorter life span. Notably, records show that most people who start taking them stop it at 12 weeks; therefore, it is important for some but not for others.
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Just like every other organ in the body, the brain changes as you get older. Ocasional subtle memory problems are usually no big deal. They are considered a part of normal ageing. However, when you see yourself repeating things or facing difficulties in accessing things quickly, like names and certain words, then it is definitely time for an evaluation. Recently, Time quoted an expert on subtle signs that indicate that you may be at risk of neurodegenerative diseases like Dementia.
7 Signs It’s Time to Take Your Memory Issues Seriously
You Have Trouble With Familiar Tasks
Many people love to multitask—jumping between texting, watching videos, and cooking dinner. That’s often doable thanks to neuroplasticity, which makes younger brains more adaptable. But as you enter middle age, your attention span tends to shrink, and life usually becomes more demanding. One day, you might find yourself staring at the toaster oven, blanking on how to use it.
You Miss Your Usual Commitments
If you begin to forget regular commitments that you've reliably handled for years, it could be more than just normal ageing. However, when to worry depends on your personal baseline. If forgetting an important event is highly out of character for you, it’s worth mentioning to a doctor. However, if you’ve been overwhelmed or unusually busy, an isolated incident may not be cause for alarm—unless it becomes a pattern.
Your Personality or Mood Changes
Many associate dementia solely with memory loss, but behavioural changes are often early signs too. Symptoms like irritability, depression, anxiety, and apathy can appear well before a diagnosis. "There's a behavioural aspect to dementia that people often overlook,' say brain scientists. In fact, these personality shifts can be seen years before Alzheimer’s is formally identified.
You Misplace Important Belongings
Imagine walking in the door, talking on the phone, and heading straight to the fridge. You put your keys down—but forget where. That’s multitasking, and it's normal. What's concerning, according to Dr. Tan, is when misplacing important things becomes frequent or disruptive. Again, it depends on your baseline. If you're naturally scatterbrained, occasional forgetfulness isn’t unusual. But if you’ve always been organized and suddenly start losing things, it could be a red flag.
You Repeat Certain Questions
Everyone has a friend who tells the same stories over and over. But if someone suddenly starts repeating questions or information they never used to, it could signal a deeper issue. If you miss something because you were distracted, like listening to music while driving, that’s understandable. But if there's no clear reason for the lapse, it might be time to pay closer attention.
You Get Lost in Familiar Places
Getting lost in places you know well is another warning sign. This often happens because of a decline in visual-spatial memory. For instance, to get to the grocery store, I know I have to turn right here, then left there, and there’s a drugstore on the corner where I make a sharp left. When that kind of route starts to confuse someone—despite paying attention—that’s a red flag, unless the place has drastically changed.
Your Parent Developed Alzheimer's At Same Age
The age at which symptoms appear often runs in families. If your mother was diagnosed with dementia at 85, forgetting where you put your keys in your early 60s may be nothing to worry about. But if she developed Alzheimer’s at 62, it’s wise to take memory lapses more seriously.
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In a refreshing departure from traditional workouts, an international team of researchers has identified a joyful and highly effective way to reduce stress, build resilience, and enhance well-being—dancing. According to a recent study published in the Psychology of Sport & Exercise, dancing not only lifts your mood but also triggers a powerful biological response that supports mental health.
“By dancing, we can tap into a natural stress-relief mechanism that enhances our resilience and helps us cope with daily pressures,” said Jonathan Skinner, co-author of the study and a researcher at the University of Surrey in the UK. “It’s fascinating to see how something as enjoyable as dance can have such profound effects on our mental health.”
The study highlights how dancing encourages the release of feel-good hormones such as endorphins and oxytocin. These chemicals are known to reduce anxiety and foster social bonding. Researchers observed a decrease in levels of cortisol—the stress hormone—as well as reductions in heart rate and blood pressure among participants who danced regularly.
Beyond the biological benefits, dancing offers psychological advantages too. It allows for emotional expression, strengthens social connections, and can be a gateway to a sense of community. “Encouraging people to move together can create a sense of belonging and support while enhancing their ability to cope with stress,” Skinner added.
In fact, a 2022 review published in Frontiers in Physiology echoed similar conclusions. It noted that dancing improves both physical and emotional health in children and adolescents, and recommended that policymakers and educators seriously consider dance-based programs to promote long-term physical activity.
For adults, dance can be a fun way to meet the World Health Organisation's recommendation of 150 minutes of moderate-intensity aerobic activity per week, along with muscle-strengthening exercises on two or more days.
The style of dance also plays a role in how many calories you burn. According to Healthline, a 150-pound person can burn around 118 calories in 30 minutes of ballroom dancing and up to 207 calories doing swing. Ballet improves strength and posture, Zumba boosts cardiovascular endurance, and even pole dancing is gaining popularity among older adults for its fitness benefits.
Whether it is salsa, hip-hop, or a kitchen dance party, the rhythm of movement could be just what your body and mind need. In a world that often prioritises high-intensity routines and rigid schedules, dance offers a more joyful, expressive path to health.
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As we today observe the World Dance Day, let us look at what dancing can help us with. Of course, the physical benefits are there. When you move your body, do any sort of physical activities, you are working out in some form and it helps you stay fit. Like everyone have their fitness regime, your dance routine can also help you stay fit. In fact there are certain fitness regime, including Zumba that keeps you fit through dance.
However, the benefits go much beyond just physical fitness, dancing can actually help you live a stress free life.
In one of the latest trends in TikTok, people are bringing back pangs of nostalgia to the internet with their 90s dance on rapper Doechii's song 'Anxiety' from the "The Fresh Prince of Bel Air".
Why is this trend important? With big names also jumping in and dancing to the rhythms, including Wil Smith and Tatyana Ali, experts say that this is helping ordinary people normalize anxiety.
Certain anxiety disorders are marked by persistent, or excessive worry. It could be fear about situations. As per the Mayo Clinic, these moments of anxiety can include panic attacks and sudden episodes of intense fear or discomfort
Research suggest that creative activities, including dancing can help relieve this stress. Dancing also engages multiple areas of the brain and demands full attention, which can then shift the focus from anxiety feelings. Supporting this idea, a 2021 study from UCLA Health found that conscious dance led to mental health improvements in a large majority of participants, particularly those dealing with anxiety, depression, or a history of trauma.
Dance involves full-body movement and coordination. This kind of physical activity stimulates the release of endorphins—natural chemicals in the brain that act as mood boosters and stress relievers. During a panic attack, when anxiety can feel overwhelming, these endorphins help calm the body and mind.
Engaging in dance also activates deep breathing patterns, especially in structured styles like Indian classical dance. This is important because panic attacks often lead to rapid, shallow breathing or hyperventilation. The breath control involved in dancing can help slow things down and regulate the body’s response.
In addition, dance improves body awareness. When someone is in the middle of a panic attack, they often feel disconnected or dissociated from reality. Focusing on movement—on the placement of your arms, the rhythm of your steps, the tension in your muscles—can bring attention back to the present. This grounding effect helps reduce the intensity of the attack and prevents it from escalating.
Experts explain that one reason dance can be so effective is because it serves as a powerful distraction. Instead of spiraling into anxious thoughts, the brain is forced to concentrate on movement, rhythm, and coordination. This temporary shift in focus can prevent panic from taking over.
Dance also builds mindfulness, a practice often recommended in therapy. Whether it's through a slow classical routine or a high-energy freestyle session, dance requires attention to the now. The combination of mental focus and physical release gives the body a chance to reset and relax.
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