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Ishita Srivastava

This Blood Type Carries The Highest Risk of Type 2 Diabetes, Scientists Find

People with blood type B, either positive or negative, are 28 percent more likely to develop <span>Type 2 diabetes</span>, according to a 2024 <span>BMC Medicine</span> study. 

Human blood is categorized into eight main groups based on the sugars and proteins, or lack thereof, present on the surface of your red blood cells.

A, B, and AB types are based on the presence of antigens, sugar molecules that can trigger an immune response. O-type blood has no A or B antigens. Meanwhile, <span>Rhesus</span> (Rh) factors are proteins that determine blood compatibility and give your blood its positive or negative designation.

According to a group of Chinese researchers, who conducted a thorough umbrella review of 270 studies, the strongest link between a <span>blood group</span> and Type 2 diabetes was between those with a <span>B blood group</span>. 

The researchers also didn't examine what might drive this increased risk. A 2025 study suggests that the gut microbiome may be involved; however, further investigation is needed.

However, the results do suggest that there's a real, tangible association between blood type and Type 2 diabetes – one that people can factor into how they think about their own risk.

Type 2 diabetes (T2D) occurs when blood sugar (glucose) remains consistently high. Normal blood sugar levels fall between 70 and 99 milligrams per deciliter (mg/dL). If undiagnosed, Type 2 diabetes often shows levels of 126 mg/dL or more.

T2D happens because the pancreas doesn’t produce enough insulin, the body can’t use insulin effectively, or a combination of both. This differs from Type 1 diabetes, which arises when the immune system attacks the pancreas, leaving the body unable to produce insulin at all.

Type 2 diabetes is widespread. Over 37 million people in the US have diabetes (around 1 in 10), with 90–95 percent of cases being T2D. Globally, it affects roughly 6.3 percent of the population. While it’s most common in adults over 45, younger adults and even children can develop it.

<h2>Blood Sugar Range For Adults And Children With Type 2 Diabetes</h2>

The American Diabetes Association recommends the following ranges for adults with type 1 or type 2 diabetes and children with type 2 diabetes:

<strong>Recommended Blood Sugar Range</strong>

1 to 2 hours after meal: Lower than 180 mg/dL

T2D has complex causes, but genes play a significant role. If one biological parent has T2D, your lifetime risk is around 40 percent, and if both parents do, it rises to 70%. Scientists have identified over 150 DNA variations linked to T2D risk, some increase the chance of insulin resistance or reduced insulin production, while others influence obesity risk. These genetic factors interact with lifestyle and health habits to determine overall risk.

<h2>How is Type 2 Diabetes Diagnosed?</h2>

Doctors use several blood tests to confirm T2D:

<ul><li>Fasting plasma glucose test: Measures blood sugar after an eight-hour fast. A result of 126 mg/dL or higher indicates diabetes.</li><li>Random plasma glucose test: Measures blood sugar at any time without fasting. A reading of 200 mg/dL or higher signals diabetes.</li><li>A1C test: Reflects average blood sugar over the past 2–3 months. A level of 6.5% or higher indicates diabetes.</li></ul>

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People with blood type B, either positive or negative, are 28 percent more likely to develop Type 2 diabetes, according to a 2024 BMC Medicine study. Human blood is categorized into eight main groups based on the sugars and proteins, or lack thereof, present on the surface of your red blood cells.A, B, and AB types are based on the presence of antigens, sugar molecules that can trigger an immune response. O-type blood has no A or B antigens. Meanwhile, Rhesus (Rh) factors are proteins that determine blood compatibility and give your blood its positive or negative designation.According to a group of Chinese researchers, who conducted a thorough umbrella review of 270 studies, the strongest link between a blood group and Type 2 diabetes was between those with a B blood group. The researchers also didn't examine what might drive this increased risk. A 2025 study suggests that the gut microbiome may be involved; however, further investigation is needed.However, the results do suggest that there's a real, tangible association between blood type and Type 2 diabetes – one that people can factor into how they think about their own risk.What is Type 2 Diabetes?Type 2 diabetes (T2D) occurs when blood sugar (glucose) remains consistently high. Normal blood sugar levels fall between 70 and 99 milligrams per deciliter (mg/dL). If undiagnosed, Type 2 diabetes often shows levels of 126 mg/dL or more.T2D happens because the pancreas doesn’t produce enough insulin, the body can’t use insulin effectively, or a combination of both. This differs from Type 1 diabetes, which arises when the immune system attacks the pancreas, leaving the body unable to produce insulin at all.How Common Is Type 2 Diabetes?Type 2 diabetes is widespread. Over 37 million people in the US have diabetes (around 1 in 10), with 90–95 percent of cases being T2D. Globally, it affects roughly 6.3 percent of the population. While it’s most common in adults over 45, younger adults and even children can develop it.Blood Sugar Range For Adults And Children With Type 2 DiabetesThe American Diabetes Association recommends the following ranges for adults with type 1 or type 2 diabetes and children with type 2 diabetes:Recommended Blood Sugar RangeFasting (before eating): 80 to 130 mg/dL1 to 2 hours after meal: Lower than 180 mg/dLIs Type 2 Diabetes Genetic?T2D has complex causes, but genes play a significant role. If one biological parent has T2D, your lifetime risk is around 40 percent, and if both parents do, it rises to 70%. Scientists have identified over 150 DNA variations linked to T2D risk, some increase the chance of insulin resistance or reduced insulin production, while others influence obesity risk. These genetic factors interact with lifestyle and health habits to determine overall risk.How is Type 2 Diabetes Diagnosed?Doctors use several blood tests to confirm T2D:Fasting plasma glucose test: Measures blood sugar after an eight-hour fast. A result of 126 mg/dL or higher indicates diabetes.Random plasma glucose test: Measures blood sugar at any time without fasting. A reading of 200 mg/dL or higher signals diabetes.A1C test: Reflects average blood sugar over the past 2–3 months. A level of 6.5% or higher indicates diabetes.

this blood type carries the highest risk of type 2 diabetes, scientists find

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