This Pill Is More Effective For Weight Loss Than Ozempic, Scientists Say

Orforglipron, a new daily pill, may be more effective than existing oral treatments for weight loss and blood sugar control than semaglutide, according to a recent clinical trial.Semaglutide belongs to a group of drugs known as GLP-1 medications, known to mimic a natural hormone that helps regulate appetite, slow digestion, and control blood sugar. The drug is commonly sold under the brand names Wegovy and Ozempic. Despite being highly effective, semaglutide usually needs to be injected and requires refrigeration, which can make it inconvenient and harder to access for some patients. Additionally, the drug also carries a high price point. However, in a 52-week trial involving people with Type 2 Diabetes, orforglipron was found to lower average blood sugar levels more than oral semaglutide and also led to greater weight loss. Participants taking orforglipron lost around up to eight kilograms on average, compared to about five kilograms with semaglutide. Morever, orforglipron is a once-daily pill that does not require injections or cold storage.But the study also found that orforglipron caused more side effects, particularly digestive issues like nausea and diarrhea. Yet scientists believe it may still be a better alternative to semaglutide as its easier and cheaper to produce than peptide-based drugs like semaglutide. They also noticed that the drug absorbed more efficiently by the body and does not require strict timing around meals, unlike current oral versions of semaglutide.READ MORE: Alkem Laboratories Launches Cheapest Semaglutide Injection In IndiaHow Does Ozempic Function?The first thing to remember here is that Ozempic is a brand-name medicine that contains semaglutide as its active ingredient. Semglutide is the synthetic version of GLP-1—a natural hormone produced in the intestines that regulates blood sugar, appetite, and digestion. Now, every time you eat, your body produces various hormones, including GLP-1. These are called Post nutrition hormones, and help you absorb the energy you just consumed.GLP-1 travels to your pancreas, prompting it to produce insulin. It also travels to the hypothalamus in your brain, which gives you the feeling of being full or satiated. Ozempic imitates this hormone, thereby, silencing the food chatter in the brain. Interestingly, for some people this food chatter is really quiet ( people with low appetite) and for others it is an outbrurst, (people who generally binge eat.) So with Ozempic, silencing this self-talk in the brain, people tend to lose their appetite and eventually weight.However, it is important to note that losing weight includes not just fat but muscle as well. Losing too much muscle can lead to reduced strength and a shorter life span. Notably, records show that most people who start taking them stop it at 12 weeks; therefore, it is important for some but not for others.Does Ozempic Have Side Effects?As reiterated by doctors and health care experts, Ozempic is a drug that is tasked to help diabetic patients manage their blood sugar levels and weight. However, recent research has shown its effectiveness in mitigating various addictions like alcohol and drugs by inhibiting hormones. But what people ignore are its side effects, which include:Nausea is a frequent side effect, especially when starting Ozempic or increasing the dose, and vomiting may occur along with nausea.Diarrhoea and abdominal discomfort also show up in people using Ozempic, but they generally resolve as your body adjusts.Ozempic can reduce appetite but may also lead to unintended weight loss or reduced food intake, causing discomfort for some people.There are certain less common, but serious side effects also, like Pancreatitis, or inflammation of the pancreas.This drug may also cause severe kidney issues, particularly if dehydration occurs from side effects like vomiting or diarrhoea.

This Pill Is More Effective For Weight Loss Than Ozempic, Scientists Say

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This Pill Is More Effective For Weight Loss Than Ozempic, Scientists Say