The tool we use to communicate and express ourselves could be the very messenger of the difficult diagnosis of cancer. Laryngeal cancer affects the larynx, the organ that helps us breathe and speak. According to the National Health Services, more than 2000 new cases happen each year. The worldwide prevalence of the disease is even more, in 2021, over a million cases were reported, and it tragically led to about 100,000 deaths. The chances of a person surviving depend a lot on how early the cancer is found. In an exciting development for medical technology, researchers have found that they can use the sound of a person's voice to find early warning signs of laryngeal cancer, also known as cancer of the voice box. Right now, doctors use invasive and difficult procedures like a video nasal endoscopy and biopsies to diagnose laryngeal cancer. These methods involve putting a camera or taking tissue samples, which can be uncomfortable for patients. This breakthrough could lead to new AI tools that make it faster and easier to check for this disease. How Voice Recordings Could Help Detect Cancer Researchers from Oregon Health and Science University studied over 12,500 voice recordings from 306 people. Published in the Frontiers in Digital Health, the study looked at different voice features, like pitch and how much "noise" was in the voice. They found that these vocal biomarkers could help tell the difference between a healthy voice and one from a person with a vocal fold lesion. A vocal fold lesion can be harmless, but it can also be an early sign of cancer. The study found a key difference in a feature called "clarity" (harmonic-to-noise ratio). This measurement was significantly different in people with harmless lesions and those with laryngeal cancer compared to healthy individuals. What Are Symptoms of Laryngeal Cancer?Laryngeal cancer, or cancer of the voice box, can have several symptoms. The most common one is a hoarse voice that lasts for more than 3 weeks. Other symptoms to watch for include: A change in your voice, such as it sounding different or hoarse.Pain or trouble when you swallow.A lump or swelling in your neck.A long-lasting cough or feeling short of breath.A sore throat or earache that doesn't go away.A high-pitched, wheezing sound when you breathe.In serious cases, you may have trouble breathing.Some people may also have bad breath, lose weight without trying, or feel extremely tired.Future of AI in Diagnosis This research suggests that voice recordings could become a simple, non-invasive way to detect cancer risks. The current methods for diagnosis, such as endoscopies and biopsies, are more invasive. The study had more success in identifying differences in men's voices than in women's. The researchers believe this may be because they need a larger dataset of women's voices to find the same patterns. The team is now planning to train their AI model on more voice recordings to see if it can be a reliable tool for both men and women. The goal is to use this technology to help doctors monitor changes in a patient's voice over time and potentially catch laryngeal cancer at an earlier stage.