Your Cholesterol Levels Could Predict Alzheimer’s Risk And Why the Wrong Meds Could Make It Worse

Updated Jun 21, 2025 | 03:32 PM IST

SummaryNew studies reveal individuals with low LDL cholesterol have a significantly reduced risk of developing Alzheimer’s disease—statin users saw even greater protection, suggesting cholesterol levels may predict and prevent dementia.
Your Cholesterol Levels Could Predict Alzheimer’s Risk And Why the Wrong Meds Could Make It Worse

Researchers might have discovered a unexpected ally in the battle against Alzheimer's disease—spearheading cholesterol-reducing medications. Recent studies indicate that medications such as statins, which have been prescribed over many years to forestall heart attacks and strokes, might also confer significant protection against mental decline.

A paper in the Journal of Neurology, Neurosurgery and Psychiatry has found that those with low levels of "bad" cholesterol (LDL-C) not only have fewer cardiac risks but also have a significantly lower risk of dementia, including Alzheimer's disease. The presence of statins in those with low LDL-C levels further increased this benefit.

These results, coupled with corroborating evidence from U.S.-based scientists, pave the way to rethink how we keep cardiovascular health in line—now with consideration of the brain.

How Cholesterol Affects Brain Health?

Statins are among the most prescribed medications worldwide, with 7–8 million individuals in the UK alone taking them to avoid cardiovascular events. The drugs act by lowering low-density lipoprotein (LDL) cholesterol, the so-called "bad cholesterol," which can block arteries and lead to heart attacks and strokes.

A more in-depth look at population-level health information from South Korea, on over 570,000 people, added a fascinating new twist: the lowest LDL-C group—below 1.8 mmol/L—were 26% less likely to have dementia and 28% less likely to have Alzheimer's than the group with LDL-C of more than 3.4 mmol/L.

Additionally, statin users with low levels of LDL-C had a further 13% lower risk of dementia and 12% lower risk of Alzheimer's than non-users.

"These results highlight the significance of LDL-C management not only in preventing heart disease but as a key component of an anticipatory approach to neurodegenerative disease prevention," researchers stated in their study. "Targeted statin prescriptions that aim at optimal levels of LDL-C could maximize cardiovascular as well as cognitive benefit."

Relationship Between Brain Function and Blood Lipids

Yet another study, this one from the Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases at UT Health San Antonio, supports the notion that the relationship between brain and cholesterol is real—but not necessarily simple.

Dr. Sokratis Charisis, a neurologist and senior researcher, examined data from the landmark Framingham Heart Study and reaffirmed that high levels of LDL are causally linked with cardiovascular disease and dementia.

Though, the information pulled a surprise in regard to HDL—often called "good cholesterol." Long hailed for its cardio-protective qualities, low levels of HDL were found to be associated with a decreased risk of Alzheimer's disease, indicating a more nuanced biological interaction between cholesterol subtypes and cognitive impairment.

"It speaks to the fact that this relationship may not be as straightforward as we believe," said Dr. Charisis. "There may be completely different mechanisms linking blood lipids to brain health as opposed to cardiovascular health."

What Really Affects Alzheimer's Risk?

Charisis also pointed out a third lipid marker—ApoB48, a lipoprotein that carries dietary fats in the blood. Though not usually tested as part of regular cholesterol checks, higher levels of ApoB48 were associated with a reduced risk of Alzheimer's, suggesting unforeseen levels of biological interplay between the diet, lipid metabolism, and brain deterioration.

"This finding is especially noteworthy," said Charisis, "because it potentially could be used to help identify a new biomarker that can ultimately inform predictive diagnostics and personalized treatment strategies."

The significance of this developing research is immense. As of 2019, an estimated 57.4 million individuals globally were affected by dementia, a figure that is predicted to increase more than twice over—that is, 152 million by the year 2050, according to international health organizations.

As Alzheimer's disease is responsible for most cases of dementia and there is no cure yet, prevention and early treatment are more essential than ever. Changes in lifestyle, reduction of cardiovascular risk, and now control of lipids could be the cornerstones of a multi-faceted approach to neurodegeneration.

While statins have traditionally been seen from the perspective of heart health, this new evidence indicates they might also be repurposed or more targeted in their prescribing for brain health, particularly among aging adults.

Yet the results also highlight the importance of individualization. What is good for one brain may not be equally useful for another, especially when age and cholesterol levels are considered. "Perhaps it will be crucial to have dynamic cholesterol targets depending on the patient's age, health status, and genetic profile," Charisis said.

This opens up the possibility of more individualized treatment regimens—not only prescribing statins by cardiac risk, but also including cognitive health evaluations in the decision-making process.

For the time being, specialists continue to recommend regular monitoring of cholesterol levels and early treatment of cardiovascular risk factors. Although you shouldn't start statin therapy just to minimize dementia risk without a doctor's advice, having a healthy LDL-C value is a definite boon to both heart and brain.

Individuals worried about cognitive impairment—particularly those with a family history of Alzheimer's—are advised to:

  • Monitor their lipid profiles on a regular basis
  • Consult with a healthcare provider regarding cholesterol-lowering therapies

Adopt habits of lifestyle that foster both cardiovascular and cognitive health: exercise, a Mediterranean diet, managing stress, and sleep

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International Yoga Day: Can Yoga Be The Antidote To Rising Teen Anxiety?

Updated Jun 21, 2025 | 09:00 PM IST

SummaryWhen just 5 minutes of yoga daily can lower stress, boost sleep, and improve focus but can it help teenagers combat early anxiety? Yoga isn’t just for adults—it’s proving to be a powerful antidote to teen anxiety. From better sleep to reduced stress hormones, simple yoga practices can truly change young lives.
International Yoga Day: Can Yoga Be The Antidote To Rising Teen Anxiety?

Observed every year on June 21st, International Yoga Day is more than a holiday honoring a health practice. It emphasises the numerous benefits of yoga for personal wellness and mindfulness, urging individuals to embrace calm amidst chaos. The age-old practice of yoga can perhaps provide young minds with a means to reboot and recall inner peace.

With teen anxiety on the increase, yoga is now being hailed not only as a means of physical exercise, but also as an intervention in mental health that can assist teens to manage emotional stress.

The Mental Health Crisis Among Teens

According to Dr. Namrata Mahajan, Counselling Psychologist & Special Educator at Artemis Hospitals, teen mental health has deteriorated significantly in recent years. "Since technology and social media became a big part of everyday life, many teens now spend hours looking at perfect pictures of themselves online, which can make them feel bad about themselves and more anxious," she explains.

Increased screen time, cyberbullying and unrealistic comparisons have led to disrupted sleep patterns, mood swings, and heightened levels of anxiety. Add to that the pressures of academic achievement, extracurricular demands and college applications and you have a complex emotional landscape.

"Many teenagers find themselves losing their sense of independence and belonging due to factors like overprotective parents, peer pressure, and bullying," Dr. Mahajan adds. The need for holistic, non-invasive tools to support their mental well-being has never been more crucial.

Rima Bhandekar, Senior Psychologist, Mpower adds in and explains, "Yoga is an accessible, practical tool that complements therapy and medication, but isn’t a magic fix. Yoga provides an effective psychological support by training the minds of the teens to live in the present moment. It can promote a sense of control, as some of the techniques like breath control and stretches can be done anytime, anywhere, which reduces the feelings of helplessness in the moment that is associated with anxiety."

What Are The Underlying Psychological And Social Triggers Behind Anxiety Among Teenagers?

There has been a rise in teen anxiety and depression in India over the past decade, with a further increase during and after the COVID-19 pandemic, due to academic performance pressure, parental expectations, and competition for limited opportunities. Teen brains have become overwhelmed with increased digital interactions, reduced self-care time, and less in-person connection with others.

Ms Rima points out, "Anxious teens often get caught in a cycle of unhelpful ways of thinking, and do not know how to calm themselves down effectively. This can cause them to avoid things, get easily upset, pull away from others, or even have panic attacks. For example, they might think, “If I don’t do well in life, I’m letting my family down,” or see things in all good or all bad light, like “I’m either best in my class or worthless.” They are likely to personalize their problems, might think like, “If my loved one is unhappy, it must be solely my fault.” These thoughts increase anxiety, making teens feel trapped in a cycle of self-blame and believing that one mistake will ruin everything they worked hard for."

How Yoga Impacts The Body Biologically?

Yoga isn’t just a spiritual or philosophical endeavor; it has tangible physiological effects on stress regulation. Dr. Mahajan explains that consistent practice can regulate cortisol levels, improve heart rate variability (HRV), and enhance sleep cycles in teenagers.

"Yoga helps lower cortisol levels, which helps calm emotional turbulence. It increases HRV, indicating better resilience and heart health by activating the parasympathetic nervous system. Yoga also boosts melatonin production, aiding restful sleep," she says.

These biochemical shifts translate into better emotional regulation, sharper focus, and a stronger sense of well-being for adolescents. The simplicity and accessibility of yoga make it an appealing choice for schools, homes, and community spaces.

According to Jyoti Singh, yoga expert and Founder & CEO of Sparsh Yog, yoga is a gentle but effective way to support teenagers through emotional turbulence. "When a teenager practices yoga, their body shifts from a stressed 'fight or flight' state to a relaxed 'rest and digest' mode," she explains.

This change is crucial for reducing anxiety. Yoga practices improve vagus nerve function, connecting the brain and body, and promoting emotional stability. Importantly, the practices don’t need to be complex.

Jyoti recommends, "Asanas like Balasana (Child’s Pose), Viparita Karani (Legs-Up-the-Wall), and Setu Bandhasana (Bridge Pose) and Pranayama such as Anulom Vilom (Alternate Nostril Breathing) and Bhramari (Bee Breath). Meditation, including mindful breathing or silent mantra chanting."

"These simple techniques bring calm, clarity, and confidence. I have seen teenagers grow emotionally stronger and more grounded through yoga," Jyoti adds.

"Yoga teaches teens to lean towards more compassion towards self and higher mental fitness, which further equips them to handle life’s challenges. Instead of reacting, teens learn to mindfully choose to act on daily living pressures by embracing uncomfortable thoughts, breathing through tough emotions, and connecting to the present moment, which builds emotional flexibility in the person. Yoga teaches to observe their anxious thoughts without labeling them, accepting them instead of suppressing or getting upset by them," says Ms Rima.

Balancing the Doshas Through Yoga

Acharya Shiv, a Yoga and Meditation expert, brings an Ayurvedic perspective to teenage anxiety. "In teens, the Pitta Dosha is dominant—symbolizing intensity, ambition, and heat. Combined with Kapha growth energy, it creates an inner fire that lacks direction," he says.

"Kapha is making them grow, that means their bones are still growing, their brain is still growing. So, in that case, I always say this to my clients and even to the students that start working on three simple pranayamas, three simple pranayamas and three postures which are extremely important for children especially and the young kids which are growing up and the youth," adds Acharya.

Yoga Asanas Effective For Teenagers

Acharya Shiv emphasizes the importance of targeted yoga routines for teens to regulate this internal imbalance. He recommends three asanas:

Veer Bhadrasana (Warrior Pose) – "It stills the body, stabilizes the heart rate, and grounds mental energy."

Balasana (Child’s Pose) – "Encourages blood flow to the brain, inducing relaxation and releasing negativity."

Matsyendra Asana (Half Lord of the Fishes Pose) – "A twisting pose that supports digestive health and the Manipura Chakra, helping teens tap into their intuition."

For pranayama, he advises:

Nadi Shodhan (Alternate Nostril Breathing) to balance the nervous system

Bhramari (Bee Breath) to quiet racing thoughts

Om Chanting for emotional purification and self-expression

"Om chanting alone can improve serotonin levels, lower cortisol, and ease anxiety-induced stuttering. It builds confidence and self-awareness," he adds.

Yoga is more than just stretching or deep breathing, it cultivates emotional literacy, helping teens identify, understand, and manage their feelings. Regular practice encourages mindfulness, fosters a sense of self-compassion, and creates a safe mental space where teens can reflect without judgment.

Yoga teaches adolescents to pause before reacting, an essential skill in emotionally charged situations. It improves attention span, reduces impulsivity, and helps young people navigate both internal and external challenges with greater poise.

Acharya Shiv emphasizes, "Teenage kids will be able to express themselves a lot better if they learn to inculcate yoga in their daily routine. I get a lot of patients who come with a problem of stuttering, children come with a problem of stuttering because they were facing anxiety. Now the moment they start doing 10-15 rounds of Om chanting, they see a huge difference in their thinking process you can say and also they could express themselves better because they were loudly chanting Om."

How Schools and Parents Can Integrate Yoga Into Teens' Lives?

Given its proven benefits, schools and parents have a vital role to play in making yoga more accessible. Morning yoga sessions, after-school yoga clubs, and even five-minute breathing breaks during class can make a profound difference.

Parents can encourage short, home-based practices, perhaps joining in themselves to model behavior. Apps, guided videos, and local community centers also offer free or low-cost ways to start.

Creating non-competitive, judgment-free yoga spaces where teens can simply show up and be present without fear of performance or appearance tanyais key to long-term engagement.

As teen anxiety continues to rise globally, yoga stands out not only as a therapeutic tool but also as a preventive practice. Unlike medication or therapy, which may come with stigma or side effects, yoga offers a natural, empowering, and holistic path to emotional stability.

On this International Yoga Day, we are reminded that some of the oldest solutions remain the most effective. For teens drowning in a sea of stress, yoga may just be the anchor they need.

Yoga can help teens who are getting more anxious. Yoga helps relax the nervous system, lower stress chemicals like cortisol, and make you stronger emotionally by focusing on breathing, moving, and being present. Yoga provides a calm place for adolescents to reset when they are feeling overwhelmed by schoolwork, social media, or their own feelings. This mind body exercise promotes equilibrium over time, not just in your body but also in your thoughts.

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India Ranks 4th In Kidney Cancer Cases, Why Is It Concerning?

Updated Jun 21, 2025 | 05:00 PM IST

SummaryKidney cancer cases are rising in India, now ranked fourth globally. Early detection, awareness of risk factors, and regular screenings from age 40 are crucial.
India among 4th globally among kidney cancer cases

Credits: Canva

Kidney cancer cases are rapidly increasing across the globe—and India has emerged as one of the top countries affected. The country currently ranks fourth in the world in terms of kidney cancer incidence, following China, the United States, and Russia. In 2025 alone, India reported 17,480 new cases, as per estimates by GLOBOCAN, a global cancer data agency.

What’s particularly concerning is that the disease is no longer confined to a specific demographic. Kidney cancer is now being diagnosed across all age groups, regardless of gender or lifestyle choices. Experts note that while urological cancers in general are seeing a rise, kidney cancer in particular is spreading at an alarming pace. This makes awareness and timely screening more critical than ever.

Know the Risk Factors

A range of lifestyle and environmental factors increase the risk of developing kidney cancer. Tobacco and alcohol use are among the most significant contributors. Obesity and high blood pressure—two conditions often linked with sedentary lifestyles—also play a major role.

Additionally, long-term exposure to certain chemicals such as asbestos, benzene, cadmium, and trichloroethylene can elevate the risk. People who work in industrial environments or in occupations with frequent chemical exposure should be especially cautious. Those with chronic kidney disease, patients on long-term dialysis, and individuals with a family history of kidney cancer are also more vulnerable.

Interestingly, the disease is significantly more common in developing nations, and the number of cases worldwide is expected to rise steeply by 2030.

Higher Prevalence in Men and the Aging Population

Statistically, men are affected by kidney cancer at nearly twice the rate of women, with a male-to-female ratio of 2:1. While the highest number of cases occurs in individuals over the age of 70, the trend is shifting. Increasingly, younger adults in their 30s and 40s are being diagnosed, likely due to changing lifestyle patterns and environmental exposure.

Symptoms That Should Not Be Ignored

Early detection of kidney cancer is often difficult because the disease rarely causes symptoms in its initial stages. However, certain signs—if persistent—should raise concern:

  • Blood in the urine – Frequently mistaken for infection or dehydration.
  • Constant pain in the flank area – On one or both sides of the lower back.
  • Noticeable lump or swelling – In the lower back or side region.
  • Unexplained fever – Triggered by substances released by the tumor.
  • Appetite loss and sudden weight loss – Occurring without any lifestyle change.
  • These symptoms can easily be overlooked or misattributed, which is why awareness is crucial.

The Importance of Early and Routine Screening

Most kidney cancers are discovered incidentally—often during ultrasounds or CT scans done for unrelated issues. When caught early, treatment outcomes can be significantly improved. Minimally invasive procedures such as laparoscopic or robotic partial nephrectomy allow surgeons to remove the tumor while preserving kidney function.

Technologies like intraoperative ultrasound (IOUS) help in real-time mapping of the tumor and surrounding blood vessels during surgery, enabling safer and more precise procedures. Robotic surgery adds another layer of precision with its 3D visualization and enhanced control.

In recent years, targeted therapies and immunotherapy have revolutionized the way advanced kidney cancer is treated, offering hope for improved survival and better quality of life.

Why Screenings Should Begin at 40

Although most kidney cancers appear between the ages of 50 and 70, cellular changes can begin much earlier. That’s why regular kidney health screenings are strongly advised starting at age 40. Annual imaging tests—particularly for those with a family history or other risk factors—can detect tumors at a stage when they are still small, localized, and easier to treat.

In the face of rising cases, timely detection and increased awareness are the most effective weapons in combating kidney cancer. With medical technologies and treatment options advancing rapidly, early diagnosis could make all the difference.

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What Is Acute Gastroenteritis? The Gastric Issue Real Madrid’s Star Footballer Kylian Mbapp Was Hospitalized For

Updated Jun 20, 2025 | 05:00 PM IST

SummaryReal Madrid star Kylian Mbappé was hospitalized with acute gastroenteritis, a stomach and intestinal inflammation often caused by viral or bacterial infections from contaminated food, water, or contact with infected surfaces.
What Is Acute Gastroenteritis? The Gastric Issue Real Madrid’s Star Footballer Kylian Mbapp Was Hospitalized For

Football fans around the world were stunned when Real Madrid confirmed that Kylian Mbappé, its French captain and marquee signing, was hospitalized for an acute bout of gastroenteritis during the Club World Cup. Although Real Madrid had originally reported that he was absent for the initial match because of illness, there was a formal medical report that confirmed the extent of his illness and in-hospital treatment and tests he required.

Even though Mbappé is recovering now with specific medical treatment outside the hospital, his sudden health fright focused fresh public attention on a prevalent but poorly understood illness: acute gastroenteritis.

What Gastroenteritis?

Gastroenteritis is the inflammation of the stomach and intestines that causes vomiting, diarrhea, cramps in the abdomen, and occasionally fever or muscle pain. Commonly called the "stomach flu," it is not caused by the flu virus and has nothing to do with respiratory infections. Rather, it is usually caused by infection or chemical irritants to the gastrointestinal (GI) tract. There are two main types:

  1. Infectious gastroenteritis – due to viruses, bacteria, parasites, or fungi.
  2. Chemical gastroenteritis – due to ingestion of poisonous substances such as some drugs, alcohol, or polluted food/water.

Mbappé's illness is an acute gastroenteritis, which means the symptoms came on suddenly and intensely but would likely pass with good care.

How Gastroenteritis Spreads?

The most prevalent reason for gastroenteritis is the intake of contaminated food or water. It is also spread by contact with infected people or surfaces they have contacted. Some typical situations include:

  • Consumption of undercooked meat or seafood
  • Inadequate washing of hands after using the toilet
  • Drinking unbottled or unfiltered water during travel

Though most individuals recover quickly, individuals with compromised immune systems—such as young children, elderly, or those with chronic diseases—are at a higher risk for developing complications like dehydration and extended illness.

Symptoms Of Gastroenteritis

Acute gastroenteritis usually presents with a combination of the following:

  • Sudden onset of watery diarrhea (non-bloody)
  • Nausea and vomiting
  • Abdominal cramps or bloating
  • Low-grade fever
  • General fatigue or muscle aches

These symptoms typically occur within 1–3 days of contact with the infection and can last anywhere from 24 hours up to two weeks, depending upon the cause and the immune response of the patient.

In the Mbappé case, the symptoms were bad enough to need hospitalization, which is not usual but required for observation of dehydration, electrolyte disturbances, or ongoing vomiting.

What Causes Gastroenteritis?

The origin of gastroenteritis comes from the inflammatory reaction in the body from a threat within the gastrointestinal system. Pathogens or toxic chemicals entering the system will have the immune reaction summon inflammation to combat invaders and heal damage.

In a majority of instances, it is an acute and transient condition. But if the infection is especially virulent or if the immune system of the body is weakened, inflammation becomes intense, aggravating symptoms and necessitating medical attention. The most common offenders are:

  • Viruses (such as norovirus and rotavirus)
  • Bacteria (E. coli, Salmonella, or Campylobacter)
  • Parasites (Giardia)
  • Fungi (uncommon but potential in immunocompromised hosts)

How Serious Is Acute Gastroenteritis?

For otherwise healthy people, acute gastroenteritis is usually self-limiting and resolves with rest and hydration. For elite athletes such as Mbappé, any alteration in the body's fluid and nutrient balance can have a profound impact on performance and recovery. The disease becomes more severe when:

  • Dehydration occurs from heavy vomiting and diarrhea
  • The symptoms do not improve after a few days
  • There is the presence of blood in stool
  • There's a loss of ability to retain fluids
  • Fever is severe and persistent

In such instances, hospitalization is advisable—as in Mbappé's case—for rehydration, electrolyte balance, and observation.

What You Can Do to Stay Safe?

Although not all gastroenteritis cases can be avoided, the risk may be drastically cut down by sensible and preventive hygiene practices. Here's how:

1. Practice Proper Handwashing

Hand washing with soap and water for 20 seconds or more, particularly before eating and after using the bathroom, is one of the best means of preventing the transmission of GI infections.

2. Safe Food Handling

Do not cross-contaminate when handling food, thoroughly cook meat, and refrigerate perishables immediately. Wash fruits and vegetables before eating.

3. Safe Water to Drink

While traveling, use sealed bottled water, don't drink ice in beverages, and eat only cooked or packaged food to minimize the risk of "traveler's diarrhea."

4. Clean Surfaces

Disinfect surfaces frequently in shared spaces such as gyms, bathrooms, or kitchens to stop the spread of infection.

5. Watch Out for Medication and Drug Use

Excessive alcohol or certain medications use can irritate the lining of the gut and lead to chemical gastroenteritis.

While Kylian Mbappé will soon return to action, his recent hospitalization is a reminder that even the best professional athletes are not beyond the reach of diseases such as gastroenteritis. It also emphasizes the value of early treatment and medical surveillance in more complicated instances.

For the general public, it is imperative that they know about the causes, symptoms, and prevention of gastroenteritis—particularly with increasing travel and food safety as an ongoing global issue. With the right information and good hygiene techniques, most instances of gastroenteritis can be prevented or treated at home. But learning when to seek assistance—such as Mbappé's medical team—is what can turn the tables.

Acute gastroenteritis is widespread, but its effect can be from mild disruption to severe health risk depending on how it is handled. As a world-class sportsman or an average person coping with day-to-day well-being, early recognition of the symptoms, fluid intake, and attention to food and hygiene safety can keep you one step ahead of this miserable but avoidable illness.

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