Name: Beyond the Stethoscope Ep. 02: Exclusive Interview With Cardiologist Dr Balbir Singh
Uploaded: 2025-09-30T14:35:39+05:30
Duration: 41 min 24 s

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world heart day 2025

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On World Heart Day 2025, we bring you an exclusive interview with renowned cardiologist Dr. Balbir Singh, who shares his expert insights on maintaining a healthy heart. In this video, Dr. Singh discusses how cholesterol affects heart health, the impact of stress on heart disease, how he approaches patient care, and more. Learn how to take proactive steps to protect your heart, manage risk factors, and understand when to seek medical advice.

On World Heart Day 2025, we bring you an exclusive interview with renowned cardiologist Dr. Balbir Singh, who shares his expert insights on maintaining a healthy heart. In this video, Dr. Singh discusses how cholesterol affects heart health, the impact of stress on heart disease, how he approaches patient care, and more.

Beyond the Stethoscope Ep. 02:  Exclusive Interview With Cardiologist Dr Balbir Singh

beyond the stethoscope ep. 02:  exclusive interview with cardiologist dr balbir singh

AI-Designed Bird Flu Vaccine Outperforms Existing Shots In Animal Study

ai-designed bird flu vaccine outperforms existing shots in animal study

FDA Probes Cancer Risk After Tumours Reported In Children Given Novartis's SMA Gene Therapy

fda probes cancer risk after tumours reported in children given novartis's sma gene therapy

NHS Data Shows 12% Increase In Kidney Cancer In People Under 50: Experts Flag Overlooked Signs

nhs data shows 12% increase in kidney cancer in people under 50: experts flag overlooked signs

US Measles Cases Cross 5,000 For First Time Since 1991; Country Risks Losing Elimination Status

us measles cases cross 5,000 for first time since 1991; country risks losing elimination status

ganga ram hospital

organ transplants

xenotransplantation

global organ shortage

organ

Can genetically engineered pig kidneys solve the global organ shortage crisis? In an exclusive conversation with Health &amp; Me, Dr Shikhar Tripathi, Director of the new department at Sir Ganga Ram Hospital, explains the latest breakthroughs in xenotransplantation. From a patient surviving 271 days with a pig kidney to the challenges of organ rejection, infection risks and long-term survival, discover how animal-to-human organ transplants could transform the future of transplantation.

Organ Transplants: Can Xenotransplantation Solve the Global Organ Shortage?

organ transplants: can xenotransplantation solve the global organ shortage?

Delhi Becomes World's Most Polluted City Ahead Of Diwali, Says Swiss Agency: Experts Recommend Precautions

delhi becomes world's most polluted city ahead of diwali, says swiss agency: experts recommend precautions

Weight Loss Without Extreme Diets: What Sustainable Medical Weight Management Looks Like

weight loss without extreme diets: what sustainable medical weight management looks like

Pregnant During Peak Pollution? A Trimester-Wise Guide to Safer Festive Celebrations

pregnant during peak pollution? a trimester-wise guide to safer festive celebrations

Breathe Easy This Diwali: Early Warning Signs & Precautions to Protect Children & Senior Citizens

breathe easy this diwali: early warning signs & precautions to protect children & senior citizens

ayurveda

air pollution

ancient india

health news

delhi pollution

At the World Congress on Health Sciences and Technology 2026, inaugurated by UPES, Prof. Dr. G. G. Gangadharan explains Ayurveda’s ancient wisdom, pollution-related health risks, pranayama, yoga, healthy eating habits, and environmental balance to support better health amid rising urban pollution.

Ayurveda & Air Pollution: Ancient Indian Wisdom to Protect Your Health | Expert Explains

ayurveda & air pollution: ancient indian wisdom to protect your health | expert explains

National Cancer Awareness Day: Diagnosed With Cancer In Your 20s Or 30s? What To Know About Fertility

national cancer awareness day: diagnosed with cancer in your 20s or 30s? what to know about fertility

Deepinder Goyal's Temple Device: Why Doctors Are Questioning Its Science

deepinder goyal's temple device: why doctors are questioning its science

COVID-19

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Ex-CDC vaccine advisor Dr Paul Offit discusses vaccine safety, COVID-19 vaccine concerns, scientific evidence and misinformation, sharing expert insights from paediatrics and vaccine education.

Why Can You Still Get COVID After Vaccination? Ex-CDC Vaccine Advisor Explains

why can you still get covid after vaccination? ex-cdc vaccine advisor explains

Why Women Prepare for Pregnancy but Rarely Prepare for Menopause

why women prepare for pregnancy but rarely prepare for menopause

Delhi Pollution: Is Your Child's Cough Or Wheezing A Warning Sign? When Should Parents Worry?

delhi pollution: is your child's cough or wheezing a warning sign? when should parents worry?

dietary supplements

supplements hidden dangers

supplements fake claims

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supplements

Are dietary supplements safe? An expert explains supplement risks, counterfeit products, protein powder testing, vitamin deficiencies, and why nutrition, exercise and sleep matter.

Dietary Supplements: Hidden Dangers, Fake Claims & How to Choose Safe Protein | Expert Explains

dietary supplements: hidden dangers, fake claims & how to choose safe protein | expert explains

Yoga-Based Cardiac Rehab May Offer A Low-Cost, Accessible Option For Heart Failure Patients

Rachel V Thomas

yoga-based-cardiac-rehab-may-offer-a-low-cost-accessible-option-for-heart-failure-patients

Cardiac Rehab

cardiac

yoga-care

Yoga Cardiac Rehab

Heart Failure

yoga

yoga for heart health

Yoga may offer more than heart health benefits. A new study presented at the American Heart Association’s Scientific Sessions 2026 suggested that yoga-based cardiac rehabilitation can improve quality of life and physical functioning in people living with heart failure. Researchers led by the Centre for Chronic Disease Control in India found that a structured yoga-based rehabilitation program improved quality of life in people with <a href="https://www.healthandme.com/health/heart-failure" data-type="tilCustomLink">heart failure</a> with reduced ejection fraction (HFrEF), compared with enhanced standard care. However, it did not significantly reduce the combined risk of death, hospitalisation or stroke. The findings are preliminary and have not yet been peer-reviewed. <h2>Why Is Yoga-Based Cardiac Rehab Important? </h2> Also read: <a href="https://www.healthandme.com/health-wellness/international-yoga-day-2026-yoga-may-help-conditions-ranging-from-male-infertility-to-arthritis-say-aiims-doctors-article-154689022" data-type="tilCustomLink">Yoga May Help Conditions Ranging From Male Infertility to Arthritis, Say AIIMS Doctors</a> Cardiac rehabilitation is a medically guided program for people who have experienced a heart attack, heart failure or heart surgery. It combines exercise guidance, education on healthy living and counselling to help patients improve their ability to carry out daily activities and reduce the risk of further cardiac events. However, access remains limited, and participation rates are low, particularly among women, older adults and some other population groups. “Cardiac rehab programs are inaccessible to many, and their uptake is poor in many countries,” said lead study author Dorairaj Prabhakaran, executive director of the Centre for Chronic Disease Control in India. He said yoga could provide several benefits of cardiac rehabilitation at a lower cost and may be easier to scale up in countries such as India. <h2>What Did The Study Find? </h2> The trial included 3,492 adults with heart failure with reduced ejection fraction across 16 medical centres in India. Participants had a median age of 57 years, and 27% were women. They were randomly divided into two groups: <ul><li>Yoga-based rehabilitation group: 1,737 participants received the Yoga-CaRe program, which combined structured yoga practices, health education and individual health goals. </li><li>Enhanced standard care group: 1,755 participants received three health education sessions over three months. </li></ul>The yoga program included 20 supervised sessions over three months, followed by one session every three months until the end of follow-up. At three months, participants in the yoga group showed significantly greater improvements in quality of life. Their scores on the Minnesota Living with Heart Failure Questionnaire improved by about eight points compared with the standard care group. Lower scores on this questionnaire indicate better quality of life. The yoga group also showed improvements in physical functioning. Participants walked an average of 25.5 metres farther in the six-minute walking test than those receiving enhanced standard care. Read More: <a href="https://www.healthandme.com/health-news/heart-failure-gets-a-new-definition-how-it-could-improve-prevention-diagnosis-and-treatment-article-154806738" data-type="tilCustomLink">Heart Failure Gets A New Definition: How It Could Improve Prevention, Diagnosis And Treatment</a> <h2> </h2><h2>Did Yoga Reduce Deaths Or Hospitalizations? </h2> Despite improvements in quality of life and physical function, yoga-based rehabilitation did not significantly reduce the combined risk of death, hospitalization or stroke. During a median follow-up of 15 months, 364 participants (21%) in the yoga group experienced one of these events, compared with 401 (22.8%) in the standard care group. The researchers said the findings support the potential of yoga-based rehabilitation in settings where conventional cardiac rehabilitation is difficult to access. <h2>Can Yoga-Based Cardiac Rehab Be An Affordable Alternative? </h2> Prabhakaran said the program could be scalable and sustainable, particularly in healthcare settings with limited resources. A single board-certified yoga and naturopathy practitioner delivered the structured program, which also recorded high participation in supervised sessions and home practice. However, the researchers have not yet conducted a formal cost-effectiveness analysis. They said further research is needed to evaluate how the program can be implemented at scale and in other healthcare settings and countries. <meta content="cms.next" name="cmsei" />

yoga-based cardiac rehab may offer a low-cost, accessible option for heart failure patients

Delhi&#39;s &#39;Severe&#39; AQI: Is Your Sore Throat More Than Pollution Irritation? When To See A Doctor

Nisha Pandey

delhis-severe-aqi-is-your-sore-throat-more-than-pollution-irritation-when-to-see-a-doctor

Delhi's 'Severe' AQI: Is Your Sore Throat More Than Pollution Irritation? When To See A Doctor

sore throat

delhi aqi

delhi air pollution

delhi aqi today

central pollution control board

delhi pollution sore throat

Dry Throat

Delhi's air quality deteriorated significantly after Diwali. Several monitoring stations recorded ‘severe’ air quality on Monday morning (November 9) after a night of Diwali festivities which resulted in widespread emission of firecracker smoke. It worsened the situation in a city already grappling with soaring air pollution due to vehicular exhaust, construction dust and stubble burning in neighbouring states. Due to this, Delhi residents, who continue to breathe polluted air, may face symptoms like scratchy throat, coughing and irritation. But how can you tell whether your sore throat is caused by pollution or an infection that needs medical attention? <h2>How Does Air Pollution Cause A Sore Throat? </h2> Polluted air contains particulate matter, including PM2.5, as well as gases and other irritants. When inhaled, these pollutants come into contact with the lining of the nose, throat and respiratory tract, triggering irritation and inflammation. Dr. Rahul Sharma, Director, Pulmonology &amp; Critical Care, Fortis Greater Noida told HealthandMe, “People exposed to high levels of pollution may experience throat irritation, dryness, a burning sensation, frequent <a href="https://www.healthandme.com/health-wellness/delhi-pollution-is-your-childs-cough-or-wheezing-a-warning-sign-when-should-parents-worry-article-156484667" data-type="tilCustomLink">coughing</a> and discomfort while swallowing. These symptoms may be more noticeable in people who spend long hours outdoors and are difficult to control.” People with asthma, allergies or existing respiratory conditions may be more sensitive to these pollutants. Dr Sharma added, “Pollution can also aggravate existing respiratory conditions like asthma and allergic airway disease. It is important to remember that a sore throat is not always due to infection; environmental exposure can also be a cause.” Also read: <a href="https://www.healthandme.com/health-news/el-nio-could-worsen-dengue-malaria-and-heat-illness-why-who-declared-a-health-emergency-article-156486794" data-type="tilCustomLink">El Niño Could Worsen Dengue, Malaria And Heat Illness: Why WHO Declared A Health Emergency</a> <h2>Pollution-Related Sore Throat Or Infection? </h2> The symptoms can overlap, so a sore throat alone cannot establish its cause. However, certain accompanying signs may offer clues. Experts help us understand when a sore throat is a result of inhaling particulate matter. Dr. Sushil Upadhyay, Consultant Pulmonologist, Kailash Deepak Hospital, Delhi told HealthandMe, “Throat irritation as an early sign. A scratchy throat is the canary in the coal mine for lung inflammation. It is the first sign that your airways defenses are overwhelmed and deep inflammation is starting.” A pollution-related sore throat is more likely to involve dryness, scratchiness, coughing and irritation of the eyes or nose. Dr Samir Garde, Director of Dept of Pulmonology and Lung Transplant, Gleneagles Hospital, Parel, told us, “Pollution-related irritation usually causes a dry or <a href="https://www.healthandme.com/health-wellness/delhi-pollution-when-is-it-a-safer-time-to-be-out-article-151070779" data-type="tilCustomLink">scratchy throat</a>, coughing and eye irritation, which may worsen outdoors or during periods of poor air quality.” An infection, on the other hand, may be accompanied by fever and other symptoms. They may include body aches, swollen lymph nodes, painful swallowing, tonsil inflammation or white patches on the tonsils. Viral infections can also cause a runny nose, cough and fatigue. Dr Upadhyay said, “The flu brings high fever, body aches, and extreme exhaustion. If staying inside an air-conditioned, filtered room clears your throat, it's pollution. Otherwise, think of it as flu.” A bacterial infection such as strep throat may cause sudden throat pain, fever and difficulty swallowing, sometimes without a cough. Also read: <a href="https://www.healthandme.com/health-news/new-covid-19-variant-pj-2-1-spreads-globally-who-says-symptoms-resemble-cold-flu-article-156486031" data-type="tilCustomLink">New COVID-19 Variant PJ.2.1 Spreads Globally: WHO Says Symptoms Resemble Cold, Flu</a> <h2>When Should You See A Doctor? </h2> A mild sore throat often improves within a week. However, medical evaluation is recommended if you have difficulty breathing, cannot swallow, are drooling because you cannot swallow, or experience rapidly worsening symptoms. Dr Upadhyay said, “Do not ignore a sore throat if it moves to your chest. If you develop wheezing, severe breathlessness or a fever, you need a medical evaluation immediately. Seek help right away if you are gasping for air or cannot finish a single sentence in one breath.” Persistent hoarseness, a lump in the neck or a mouth ulcer lasting more than three weeks should also be evaluated. Dr Garde recommended, “Seek medical attention if there is chest tightness, high fever or persistent symptoms. Severe <a href="https://www.healthandme.com/health-wellness/can-prolonged-exposure-to-pm2-5-increase-the-risk-of-blood-clots-and-stroke-article-156481048" data-type="tilCustomLink">breathlessness</a>, bluish lips or difficulty speaking due to breathing problems require immediate emergency care.” Also read: <a href="https://www.healthandme.com/health-wellness/delhi-aqi-crosses-2000-mark-after-diwali-what-happens-to-your-body-within-hours-of-exposure-article-156484175" data-type="tilCustomLink">Delhi AQI Crosses 2,000 Mark After Diwali: What Happens To Your Body Within Hours Of Exposure?</a> <h2>How Can You Protect Your Throat During Severe Pollution? </h2> According to the doctors, while pollution levels remain high, reducing exposure is important. They recommend: <ul><li>Avoid outdoor exercise and limit unnecessary time outside.</li><li>Wear a well-fitting N95 or N99 respirator when going outdoors.</li><li>Keep windows closed during periods of high outdoor pollution and use a HEPA air purifier if available.</li><li>Drink enough water to prevent throat dryness.</li><li>Gargle with warm salt water to soothe irritation.</li><li>Avoid smoking, incense and other indoor sources of smoke.</li></ul> Do not start antibiotics just because your throat hurts. Antibiotics do not treat throat irritation due to pollution or viral infections. They should only be used when prescribed for a confirmed bacterial infection under doctor’s supervision. <h2>Delhi AQI After Diwali </h2> <div type="Youtube" id="tGdVU0SoMLE" title="Is AI Affecting Your Brain? Doctor on Cognitive Health, Parkinson’s &amp; Dementia" thumbUrl="https://i.ytimg.com/vi/tGdVU0SoMLE/mqdefault.jpg"><url><![CDATA[https://youtu.be/tGdVU0SoMLE?si=TYwLE8Y8LzkUI_8y]]></url></div> The city's average Air Quality Index (AQI) reached 406 on November 9, placing it in the 'severe' category, according to the Central Pollution Control Board (CPCB). But private monitoring platform AQI.in reported an AQI of 2,283, classifying the air quality as ‘hazardous’. The reading showcased a grim post-Diwali pollution peak, an issue that has turned into an annual environmental crisis. The stark difference in readings is because India’s AQI scale is limited to 500 while other private air quality monitoring platforms measure higher readings. So even if CPCB’s data shows 500 AQI, it can mean that the amount of harmful pollutants could be much higher. The Supreme Court had implemented restrictions on celebrating Diwali with firecrackers by limiting time between 6 am and 7 am and 8 pm and 10 pm on November 7 and 8 and allowing only green crackers. However, firecrackers were reportedly burst beyond permitted hours.<meta content="cms.next" name="cmsei" />

delhi's 'severe' aqi: is your sore throat more than pollution irritation? when to see a doctor

El Niño Could Worsen Dengue, Malaria And Heat Illness: Why WHO Declared A Health Emergency

el nio

El Nino

COP31

climate change and health

Health Emergency

antnio guterres

world meteorological organization

The developing El Niño event could intensify heatwaves, droughts and extreme rainfall into 2027, increasing health risks worldwide, including heat-related illnesses and infectious diseases such as dengue, malaria and cholera, according to a new World Meteorological Organization (WMO) report. The State of the Climate in 2026 report, released during COP31 in Türkiye, warned that El Niño will amplify the health impacts of climate change. In view of this, the World Health Organization (WHO) has, for the first time, classified the anticipated health impacts as a health emergency. The report warns of increased heat-related deaths, wildfire smoke exposure, poor air quality, malnutrition, injuries and changing risks of water- and vector-borne diseases. "We have entered a new age of climate extremes. A supersized El Niño is colliding with a planet already superheated by manmade climate change," UN Secretary-General António Guterres said. <h2>How Could El Niño Affect Health? </h2> Read More: <a href="https://www.healthandme.com/health-news/climate-change-is-already-harming-health-who-chief-pushes-antalya-initiative-at-cop31-article-156485685" data-type="tilCustomLink">Climate Change Is Already Harming Health: WHO Chief Pushes Antalya Initiative At COP31</a> El Niño is a natural climate phenomenon involving warmer-than-average sea-surface temperatures in the central and eastern equatorial Pacific. It influences weather patterns worldwide and can raise global temperatures. The current event is expected to continue into early 2027. According to the WMO, its health impacts could include: <ul><li>Extreme heat: More intense heatwaves, heat-related illnesses and deaths.</li><li>Poor air quality: Increased wildfire smoke and pollution exposure.</li><li>Infectious diseases: Changing risks of dengue, malaria and cholera.</li><li>Food insecurity: Disrupted agriculture, malnutrition and water shortages.</li><li>Extreme weather injuries: Greater risks from floods, storms and other disasters.</li></ul> Vulnerable communities with limited healthcare access and high dependence on rain-fed agriculture could face the greatest risks. <h2>2026 Among Four Warmest Years On Record </h2> Further, the report noted that the past 12 years have individually been the warmest on record, with 2023–2026 ranking as the four warmest. Global average temperatures from January to September 2026 were 1.47°C above the 1850–1900 pre-industrial average. The figure could rise further by year-end as El Niño strengthens. The event has been intensifying since August and is forecast to continue into early 2027. WMO Secretary-General Celeste Saulo said El Niño was releasing heat from already warming oceans. "El Niño doesn't add new heat to the planet. It releases heat from the ocean, which is the warmest ever measured. There is simply more heat available to release," she said. <div type="image" title="El Niño Could Worsen Dengue, Malaria And Heat Illness: Why WHO Declared A Health Emergency" msid="156487066" hostid="1005" sizebytes="69214" caption="&amp;lt;p&amp;gt;Credit: WMO&amp;lt;/p&amp;gt;"></div> <h2>Extreme Weather Is Already Taking A Toll </h2> The report highlights the human cost of climate extremes across several regions. <ul><li>Europe: Heatwaves, droughts and wildfires contributed to more than 30,000 excess deaths, according to preliminary estimates.</li><li>India: An estimated 146.5 million people were exposed to extreme heat during an April 2026 heatwave.</li><li>Nepal: A glacier collapse and downstream flash floods in August killed more than 1,300 people and severely affected the country's economy.</li></ul> <h2>Oceans Continue To Warm As Glaciers Melt </h2> Also read: <a href="https://www.healthandme.com/health-news/global-temperatures-likely-to-stay-near-record-levels-for-next-five-years-wmo-article-154425085" data-type="tilCustomLink">Global Temperatures Likely To Stay Near Record Levels For Next Five Years: WMO</a> Earth's energy imbalance reached its highest level since monitoring began in 1960, as greenhouse gases trap more heat in the climate system. The oceans absorb around 90% of this excess heat. Ocean heat content in the upper 2,000 metres reached a record high in 2025 and continued rising in 2026. Global sea levels also reached a record high in 2026, driven by melting glaciers and ice sheets and the expansion of warming seawater. <h2>Early Warning Systems Show Progress </h2> The number of countries reporting multi-hazard early warning systems increased from 56 in 2015 to 136 in 2025. These systems help communities prepare for extreme weather and reduce risks to lives and livelihoods. The WMO stressed that sustained climate monitoring and reliable forecasts are increasingly important as extreme weather intensifies.<meta content="cms.next" name="cmsei" />

el niño could worsen dengue, malaria and heat illness: why who declared a health emergency

New Weight Loss Drug Mazdutide Shows 18% Weight Loss In 32 Weeks: How Does It Compare To Wegovy?

new-weight-loss-drug-mazdutide-shows-18-weight-loss-in-32-weeks-how-does-it-compare-to-wegovy

Lancet Study Says Obesity Drug Mazdutide Shows 18% Weight Loss In 32 Weeks: How Does It Compare To Wegovy?

mazdutide

ozempic

lancet diabetes & endocrinology

eli lilly

mazdutide study

mazdutide weight loss drug

mazdutide eli lilly

wegovy

glucagon

new england journal of medicine

Mazdutide, an experimental weight-loss drug, could soon join the ever-expanding market of GLP-1 medications. The results from a recent clinical trial funded by Eli Lilly has found that mazdutide has shown an average reduction of 18.1% in body weight over 32 weeks. The trial was published in The Lancet Diabetes &amp; Endocrinology. The findings have drawn attention because the experimental drug produced significant weight loss in less than eight months, establishing its position among existing medicines like Wegovy. However, the findings come from a phase 2 trial involving 179 participants. Its comparison with existing players like Wegovy are yet to be done formally. <h2>What Did The Mazdutide Study Find? </h2> Also read: <a href="https://www.healthandme.com/health-wellness/ozempic-mounjaro-users-report-burning-skin-sensation-what-is-allodynia-article-156473406" data-type="tilCustomLink">Ozempic, Mounjaro Users Report Burning Skin Sensation: What Is Allodynia?</a> Published in November 2026, the randomised, double-blind, placebo-controlled trial evaluated mazdutide in 179 overweight or obese adults with overweight but without <a href="https://www.healthandme.com/health-wellness/nick-jonas-opens-up-about-living-with-type-1-diabetes-for-more-than-2-decades-what-does-it-entail-article-156485530" data-type="tilCustomLink">type 2 diabetes</a>. Participants, who were recruited from 24 centres in the United States, received the once-weekly injections of different doses of the drug or a placebo. At 32 weeks, the average weight changes were: <ul><li>Mazdutide 16 mg: 18.1% reduction in body weight</li><li>Mazdutide 10 mg: 15.6% reduction</li><li>Mazdutide 3–6 mg: 7.3% reduction</li><li>Placebo: 0.9% reduction</li></ul> The study also reported further weight reductions by week 48, suggesting that weight loss had not reached its maximum by the primary assessment. However, tolerability of the drug drew attention too. Gastrointestinal problems, including nausea, vomiting and diarrhoea, were among the most common side effects. Around 20% of participants receiving the highest 16 mg dose quit the treatment because of adverse events, primarily gastrointestinal disorders. <h2>How Does Mazdutide Work? </h2> Also read: <a href="https://www.healthandme.com/health-wellness/australia-approves-first-glp-1-weight-loss-pill-how-it-works-who-is-eligible-article-156464346" data-type="tilCustomLink">Australia Approves First GLP-1 Weight Loss Pill: How It Works &amp; Who Is Eligible</a> Mazdutide works differently from semaglutide, the active ingredient in <a href="https://www.healthandme.com/health-news/godzilla-drug-retatrutide-reverses-sleep-apnea-in-1-in-4-diabetes-patients-article-156425113" data-type="tilCustomLink">Ozempic</a> and Wegovy. It activates two hormone receptors involved in regulating appetite and metabolism: glucagon-like peptide-1 (GLP-1) and glucagon. GLP-1 helps regulate blood sugar, which slows down emptying of the stomach and increases feelings of fullness, which can reduce food intake. Glucagon is another hormone involved in regulating blood glucose and energy metabolism. By activating glucagon receptors along with GLP-1 receptors, mazdutide can affect energy expenditure and metabolism in addition to regulating appetite. This dual action distinguishes it from semaglutide, which primarily targets the GLP-1 receptor. <h2>Mazdutide Vs Wegovy </h2> Also read: <a href="https://www.healthandme.com/health-wellness/glp-1-drugs-may-be-more-effective-than-metformin-at-preventing-diabetes-study-article-156455262" data-type="tilCustomLink">GLP-1 Drugs May Be More Effective Than Metformin At Preventing Diabetes: Study</a> Ozempic and Wegovy contain the same active ingredient, semaglutide, but have different approved uses and dosing. Ozempic is primarily prescribed for type 2 diabetes and certain cardiovascular and kidney conditions, while Wegovy is approved for weight management.Here is how the trial results compare: Mazdutide 16 mg showed 18.1% weight reduction in 32 weeks. Wegovy 2.4 mg showed 14.9% in 68 weeks. In the STEP 1 trial, published in The New England Journal of Medicine in 2021, participants with overweight or obesity who received semaglutide 2.4 mg lost an average of 14.9% of their body weight over 68 weeks. Participants did not have diabetes. Although mazdutide's 18.1% result seems higher than the 14.9% reported with <a href="https://www.healthandme.com/health-news/eli-lilly-can-continue-zepbound-ads-despite-novo-nordisks-claims-over-weight-loss-drug-comparisons-article-156412005" data-type="tilCustomLink">Wegovy</a>, the comparison has limitations. The trials differed in duration, participant characteristics, doses and study design. A direct head-to-head trial would be needed to establish which treatment produces greater weight loss. <div type="Youtube" id="4gZHwxFG4UI" title="How to Enjoy Diwali on Ozempic &amp; Mounjaro | Doctors Share GLP-1 Diet Tips" thumbUrl="https://i.ytimg.com/vi/4gZHwxFG4UI/mqdefault.jpg"><url><![CDATA[https://youtu.be/4gZHwxFG4UI?si=eP74oNW7UKZ0IxAL]]></url></div> <h2>Is Mazdutide A Promising Weight-Loss Drug? </h2> Mazdutide has also been studied in China. In the phase 3 GLORY-2 trial, participants receiving 9 mg lost an average of 16.65% of their body weight over 60 weeks, compared to 1.50% in the placebo group. Its recent findings are promising but it is too early to call mazdutide more effective than existing treatments. The US study was a relatively small phase 2 trial, and its highest dose led to a high rate of discontinuation due to adverse events. Larger phase 3 trials are important to establish its long-term effectiveness, safety and tolerability.<meta content="cms.next" name="cmsei" />

new weight loss drug mazdutide shows 18% weight loss in 32 weeks: how does it compare to wegovy?