Health and Me

Rachel V Thomas

Australian Techie Uses ChatGPT, Grok To Develop 1st Personalized Cancer Vaccine For His Dog

Australian Techie Uses ChatGPT, Grok To Develop 1st Personalized Cancer Vaccine For His Dog

In a first, a tech entrepreneur from Australia, Paul Conyngham, has claimed to have developed a personalized cancer vaccine for his dog, Rosie, using two popular Artificial Intelligence (AI) chatbots -- ChatGPT from OpenAI and Grok, built by Elon Musk's xAI.

Conyngham's eight-year-old rescue dog developed large tumors on her legs and was diagnosed with mast cell cancer -- the most common skin cancer in dogs.

Rosie, a staffy-cross-shar pei, had multiple surgeries, chemotherapy, and immunotherapy. While that could slow down the disease, it could not help stop her tumor growth. Vets then gave her a maximum of 6 months to live. 

However, not willing to give up on his "best mate" who has been with him "through really tough times", Conyngham turned to AI, The Australian reported. 

Conyngham, leveraging 17 years of his expertise in data science and artificial intelligence, used ChatGPT and Google DeepMind 's AlphaFold to develop a plan, along with researchers at the University of New South Wales.

"The final vaccine construct for Rose was designed by Grok," Conyngham shared in a post on social media platform X. 

The team analyzed two samples of DNA — one healthy, and one from Rosie's cancer. He explained that they converted the tumor into DNA data and used it to develop a treatment, with guidance from ChatGPT throughout the process.

After analyzing protein structures linked to cancer, customized mRNA vaccine was designed to target specific mutations in Rosie's tumor. The vaccine was administered to Rosie in December 2025.

Rosie is now showing significant improvement, and the tumor has reportedly shrunk by half.  Conyngham was even shocked to see her jump over a fence while chasing a rabbit.

"This represents a breakthrough in personalized medicine," said Professor Páll Thordarson from UNSW. He added that Rosie’s case shows mRNA-based personalized therapies can be effective and applied quickly, with potential lessons for human treatments. 

Despite the positive signs, Conyngham remains cautious. “I’m under no illusion that this is a cure, but I do believe this treatment has bought Rosie significantly more time and quality of life.”

He is now working on developing another vaccine to target a remaining tumor. Conyngham also believes that this approach may one day change how some cancers are treated, and is now helping people who are facing the disease with their pet friends. 

"A lot of people have been asking if this can be done for their dogs and for people. I'm speaking with everyone involved to see what is possible here," Conyngham wrote on X, asking them to connect personally via a Google form.

Health Conditions A-Z

health

Personalized Cancer Vaccine

Paul Conyngham

mast cell cancer

ChatGPT

Grok

OpenAI

Elon Musk

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In a first, a tech entrepreneur from Australia, Paul Conyngham, has claimed to have developed a personalized cancer vaccine for his dog, Rosie, using two popular Artificial Intelligence (AI) chatbots -- ChatGPT from OpenAI and Grok, built by Elon Musk's xAI. Conyngham's eight-year-old rescue dog developed large tumors on her legs and was diagnosed with mast cell cancer -- the most common skin cancer in dogs. Rosie, a staffy-cross-shar pei, had multiple surgeries, chemotherapy, and immunotherapy. While that could slow down the disease, it could not help stop her tumor growth. Vets then gave her a maximum of 6 months to live. However, not willing to give up on his "best mate" who has been with him "through really tough times", Conyngham turned to AI, The Australian reported. Conyngham, leveraging 17 years of his expertise in data science and artificial intelligence, used ChatGPT and Google DeepMind 's AlphaFold to develop a plan, along with researchers at the University of New South Wales."The final vaccine construct for Rose was designed by Grok," Conyngham shared in a post on social media platform X. The team analyzed two samples of DNA — one healthy, and one from Rosie's cancer. He explained that they converted the tumor into DNA data and used it to develop a treatment, with guidance from ChatGPT throughout the process.After analyzing protein structures linked to cancer, customized mRNA vaccine was designed to target specific mutations in Rosie's tumor. The vaccine was administered to Rosie in December 2025.Rosie is now showing significant improvement, and the tumor has reportedly shrunk by half.  Conyngham was even shocked to see her jump over a fence while chasing a rabbit."This represents a breakthrough in personalized medicine," said Professor Páll Thordarson from UNSW. He added that Rosie’s case shows mRNA-based personalized therapies can be effective and applied quickly, with potential lessons for human treatments.  Despite the positive signs, Conyngham remains cautious. “I’m under no illusion that this is a cure, but I do believe this treatment has bought Rosie significantly more time and quality of life.”He is now working on developing another vaccine to target a remaining tumor. Conyngham also believes that this approach may one day change how some cancers are treated, and is now helping people who are facing the disease with their pet friends.  "A lot of people have been asking if this can be done for their dogs and for people. I'm speaking with everyone involved to see what is possible here," Conyngham wrote on X, asking them to connect personally via a Google form.