When the U.S. Food and Drug Administration (FDA) convened a public expert panel to review the use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy, it re-opened a long-standing and highly charged conversation. At the center of the debate: how to weigh the risks of antidepressants to fetal development against the dangers of untreated maternal depression.

With no clear outcome or regulatory shift announced at the end of the meeting, the session highlighted just how divided experts remain over SSRIs—a class of drugs that includes some of the most commonly prescribed medications in the U.S., such as Prozac, Lexapro, and Zoloft.

The FDA forum, led by Commissioner Dr. Marty Makary, brought together perinatal psychiatrists, developmental biologists, epidemiologists, obstetricians, and mental health clinicians. The focus? Whether SSRIs prescribed during pregnancy need stronger warnings, including a potential “black box” label—the FDA’s most serious caution.

Dr. Makary opened the session with a sobering observation: nearly one in four middle-aged American women is on an antidepressant, and approximately 5% of pregnant women are prescribed SSRIs. Despite the increasing use of these drugs, he pointed out that the broader mental health picture in the U.S. hasn’t improved. “The more antidepressants we prescribe, the more depression there is,” he said, urging a deeper look at root causes instead of pharmaceutical fixes alone.

Nine of the ten panelists had previously voiced public concerns about SSRI safety or expressed skepticism toward antidepressant efficacy. Many cited studies indicating potential neurodevelopmental risks in babies exposed to SSRIs in utero. These include associations with autism spectrum disorders, ADHD, and other cognitive challenges.

However, these claims were not universally accepted. Independent researchers and clinicians noted that several of the studies referenced lacked proper controls, making it difficult to determine whether adverse outcomes were caused by the medications, the underlying depression itself, or other unrelated factors like maternal stress, environmental exposures, or socioeconomic influences.

Critically, many of the panelists underemphasized—or ignored entirely—the well-documented risks of untreated perinatal depression. Suicide remains one of the leading causes of maternal death in the first year postpartum. Depression during pregnancy has also been associated with premature birth, low birth weight, and impaired bonding with the baby.

There’s no question SSRIs, like any medication, carry risk. But context matters. SSRIs aren’t prescribed casually; they’re part of a personalized treatment plan that often includes psychotherapy, lifestyle interventions, and close monitoring.

Experts caution against blanket restrictions or alarmist warnings. While acknowledging the importance of ongoing research and transparency in labeling, several physicians worry that exaggerated claims could have unintended consequences—mainly, deterring pregnant women from seeking care.

“We need to be careful not to scare patients away from treatment that might be lifesaving,” said one perinatal psychiatrist unaffiliated with the FDA panel. “Depression doesn’t disappear during pregnancy. For many women, it gets worse.”

The debate over SSRIs isn’t happening in a vacuum. It’s unfolding against a backdrop of shifting political narratives around mental health, medication, and government oversight.

Robert F. Kennedy Jr., now Health and Human Services Secretary under former President Trump, has been a vocal critic of SSRIs and other psychiatric medications. His “Make America Healthy Again” initiative frames SSRIs as part of a broader pharmaceutical overreach. He’s even gone so far as to claim a link between antidepressants and school shootings—an assertion for which no scientific evidence exists.

During the FDA panel discussion, one participant echoed Kennedy’s alarmist rhetoric, declaring, “Never before in human history have we chemically altered babies like this.” Comments like these, healthcare professionals argue, blur the line between evidence-based discussion and ideological fearmongering.

The reality on the ground is more nuanced. Clinicians treating pregnant patients with depression must weigh competing risks with every prescription. Factors like a woman’s mental health history, her past response to medications, current symptoms, support system, and overall health are all taken into account.

Many OB-GYNs and psychiatrists recommend continuing SSRIs during pregnancy if the patient has a history of severe depression or has responded well to the medication. The cost of relapse—both emotionally and physically—can be high. In contrast, women with milder symptoms might consider tapering off or trying non-drug therapies under medical supervision.

And while some studies suggest a possible association between SSRI use and neurodevelopmental issues in children, the evidence is not conclusive. In many cases, what appears to be a risk may be confounded by the effects of the illness itself.

Despite the heated debate, the FDA did not announce any immediate regulatory action following the panel meeting. An agency spokesperson emphasized that the session was part of “broader efforts to apply rigorous, evidence-based standards” in evaluating drug safety, particularly during sensitive periods like pregnancy.

Still, the session underscored a growing demand for more nuanced research and improved labeling that fully informs patients without generating unnecessary fear. The agency’s next steps remain unclear, but stakeholders on all sides agree: this is a conversation that’s far from over.

Can SSRIs Harm Unborn Babies?

The question of whether selective serotonin reuptake inhibitors (SSRIs) can harm unborn babies is complex—and not definitively answered. SSRIs are widely prescribed to manage depression and anxiety, including during pregnancy. But recent scrutiny by an FDA advisory panel has reignited concerns about their safety, particularly in the first trimester when fetal development is most vulnerable.

Studies over the years have linked SSRI use in pregnancy to a small but possible increased risk of complications such as low birth weight, premature birth, neonatal adaptation syndrome (withdrawal-like symptoms in newborns), and persistent pulmonary hypertension of the newborn (PPHN). Some data even suggest a potential link between early SSRI exposure and neurodevelopmental issues, including autism spectrum disorders, though these findings are inconclusive and often confounded by the severity of maternal depression itself.

On the flip side, untreated depression during pregnancy also carries serious risks—for both mother and child. It can lead to poor prenatal care, higher rates of substance use, inadequate nutrition, and increased risk of suicide or self-harm. These factors can impact fetal outcomes as well.

As public health agencies and professionals continue to assess the benefits and risks of SSRIs during pregnancy, one thing is clear: blanket judgments and politicized narratives don’t help patients. What pregnant individuals need is clear, evidence-based guidance—and compassionate, personalized care that prioritizes both maternal and fetal health.

The question of whether selective serotonin reuptake inhibitors (SSRIs) can harm unborn babies is complex—and not definitively answered. SSRIs are widely prescribed to manage depression and anxiety, including during pregnancy. But recent scrutiny by an FDA advisory panel has reignited concerns about their safety, particularly in the first trimester when fetal development is most vulnerable.

Studies over the years have linked SSRI use in pregnancy to a small but possible increased risk of complications such as low birth weight, premature birth, neonatal adaptation syndrome (withdrawal-like symptoms in newborns), and persistent pulmonary hypertension of the newborn (PPHN). Some data even suggest a potential link between early SSRI exposure and neurodevelopmental issues, including autism spectrum disorders, though these findings are inconclusive and often confounded by the severity of maternal depression itself.

On the flip side, untreated depression during pregnancy also carries serious risks—for both mother and child. It can lead to poor prenatal care, higher rates of substance use, inadequate nutrition, and increased risk of suicide or self-harm. These factors can impact fetal outcomes as well.

SSRIs aren’t inherently harmful, but their use during pregnancy must be carefully evaluated. For some, the benefits outweigh the risks—especially when mental health is at stake. Always consult a healthcare provider for personalized guidance.

Teddi Mellencamp Cancer Update: Reality TV star and podcast host Teddi Mellencamp has revealed she is pausing her immunotherapy treatment as part of her ongoing battle with stage 4 cancer.

In an update during the July 24 episode of her podcast Two T’s in a Pod, Mellencamp shared that her body has been struggling to cope with the effects of the aggressive treatment, despite promising results in shrinking tumors.

The 44-year-old former Real Housewives of Beverly Hills cast member detailed that she had not been feeling well for nearly a month and had grown increasingly fatigued and disoriented. “It was kind of shocking to me, and I think mentally it did a lot to me,” she said. “I started asking myself, ‘Why do I feel like I can barely open my eyes or keep my words straight?’”

After undergoing emergency scans and consulting her doctors, Mellencamp was told that the sickness she was feeling wasn’t from the cancer itself, but from the very treatment designed to help her.

Immunotherapy on Hold for Now

Immunotherapy, a treatment that harnesses the body's immune system to fight cancer, has shown signs of success in Mellencamp’s case. Doctors confirmed that the tumors in her lungs and brain were shrinking. “They did a bunch of scans and everything’s looking good, everything’s shrinking,” she said on the podcast.

However, the toll on her body has forced a critical decision, take a break to recover strength.

“So we’re going to take a little break on the immunotherapy to get my body back feeling stronger,” she revealed, adding that she is now on steroids and other medications to stabilize her condition. “I’m doing everything I can to get back to feeling like I can do this.”

She added, “I’ve never once felt this way until recently. And it’s heartbreaking.”

A Long Battle with Skin Cancer

Teddi Mellencamp’s cancer journey began in October 2022 when she was first diagnosed with skin cancer. Over the next year, she underwent multiple biopsies and surgeries, eventually revealing in early 2024 that the cancer had progressed to stage 4 and spread to her brain and lungs.

In February, she underwent emergency surgery to remove several brain tumors. But by April, new tumors had appeared. Despite these setbacks, Mellencamp kept her spirits high. She has also been regularly updating her fans with health progress, including the encouraging news just two months ago that her tumors were visibly shrinking.

“And then today I had the scan where they checked my lungs, and they are shrinking, and one of them has shrunk so much you can barely even see it,” she had shared at the time.

What Is Skin Cancer?

Skin cancer is the abnormal growth of skin cells, most often caused by overexposure to the sun’s ultraviolet (UV) rays. The most common types are basal cell carcinoma, squamous cell carcinoma, and melanoma—the most aggressive form, which can spread to other organs if not detected early.

While treatable in early stages, late-stage skin cancer that metastasizes (spreads to other parts of the body) becomes significantly harder to control. Treatments often include surgery, radiation, chemotherapy, and newer therapies like immunotherapy. Mellencamp’s cancer appears to be an advanced form, as it is in Stage IV and has spread to other parts of her body, requiring constant monitoring and multidisciplinary care.

Despite filing for divorce in November 2024, Edwin Arroyave, her husband has remained by Mellencamp’s side throughout her cancer treatment. “He’s had to step in and help me because I, some days, can’t do it,” she admitted during the podcast. “Nothing’s changed in that other than that [we’re] on hold because of what’s happening to me medically.”

For now, Mellencamp is focusing on recovery and regaining enough strength to resume treatment. “I can do all the things,” she said hopefully. “Just not today—but maybe soon.”

World IVF Day, also known as World Embryologist Day, is observed every year on July 25 to mark the groundbreaking advancements in infertility treatment and assisted reproductive technology (ART).

It celebrates the efforts of scientists, embryologists, and clinicians who have helped transform the dreams of parenthood into reality for millions of couples worldwide. On this day, medical communities globally, particularly those specializing in fertility, organize seminars, workshops, and symposiums to share knowledge, explore the latest innovations, and raise awareness about infertility.

World IVF Day, History And Origin

In vitro fertilization (IVF) is a form of assisted reproductive technology where eggs are fertilized by sperm outside the body in a laboratory. Once fertilized, the embryo is transferred into the uterus to establish a successful pregnancy. IVF has brought hope to countless families struggling with infertility—especially those for whom traditional conception is not possible.

The origin of World IVF Day dates back to July 25, 1978, when Louise Brown, the world’s first "test-tube baby," was born in England.

This revolutionary birth was made possible through the combined efforts of Dr. Robert Edwards, Dr. Patrick Steptoe, and nurse Jean Purdy, who carried out the pioneering IVF work at Dr. Kershaw’s Cottage Hospital. After years of failures, including 102 unsuccessful embryo transfers, their success reshaped reproductive medicine forever.

Dr. Steptoe’s expertise in laparoscopy and Dr. Edwards’ research in embryology laid the foundation for this monumental achievement.

World IVF Day 2025: This Year’s Theme

The theme for World IVF Day 2025 is “Science of Life: Ethics, Innovation, and Hope.”

This theme pays tribute to the role of embryologists, the often unsung heroes behind the scenes, and the ethical frameworks that guide IVF practices.

It stresses the importance of responsible innovation in reproductive technology while reinforcing the core reason behind these efforts: to offer hope to those longing to become parents. With rapid progress in areas like genetic testing, embryo freezing, and preimplantation diagnostics, the conversation around ethics and accessibility is more relevant than ever.

Why The World IVF Day Matters: The Day's Significance

Louise Brown’s birth wasn’t just a medical marvel; it symbolized the start of a new era. Choosing July 25th as World IVF Day commemorates that moment of breakthrough and honors the relentless perseverance of scientists and doctors who refused to give up. Today, this date is more than a celebration, it’s a reminder of how science can bridge the gap between despair and possibility for families worldwide.

The Growing Need: Infertility by the Numbers

Infertility, defined as the inability to conceive after 12 months of unprotected intercourse, affects one in six people globally, according to WHO estimates.

For every 100 couples trying to conceive naturally, about 84 will succeed within a year, 92 by two years, and only 93 by three years.

If conception doesn’t occur within three years, the chances of natural pregnancy drop to just 25%.

Meanwhile, fertility rates are dropping globally. In 1950, women had an average of 4.7 children; by 2017, that number halved to 2.4, and it's expected to reach 1.7 by 2100, according to The Lancet. In 23 countries, including Spain and Japan, the population is projected to halve due to declining fertility. In such circumstances, IVF and related technologies aren’t just a personal lifeline—they are becoming a societal necessity.

Doctors often stress that lifestyle changes can reduce infertility risks:

For Women:

• Avoid smoking and excessive alcohol.
• Don’t delay conception unnecessarily.
• Engage in moderate exercise.
• Maintain a healthy body weight.

For Men:

• Refrain from smoking, alcohol, and illegal drug use.
• Wear loose, breathable undergarments.
• Maintain a balanced weight.
• Avoid prolonged exposure to heat sources (like saunas and hot tubs).

Ready meals could save us a lot of time, but at what cost? Your life. They taste great and are available at every major supermarket. But what happens when convenience turns into catastrophe? This very question is now haunting shoppers across Ireland and the UK after a listeriosis outbreak claimed a life and triggered widespread recalls of chilled ready meals.

The outbreak has been traced back to Ballymaguire Foods, a supplier whose products were sold at major chains like Aldi and Tesco. One adult has already died after falling ill from a contaminated dish, and more cases are under investigation. This isn’t just a random scare; it’s a sharp reminder that foodborne infections can hit fast and hit hard.

What is Listeriosis?

Caused by the Listeria monocytogenes bacteria, listeriosis might sound like just another food-related illness. But for vulnerable groups, it’s anything but trivial. Those most at risk include older adults, people with weakened immune systems, pregnant women, and infants. In fact, earlier this year, listeria-contaminated chocolate desserts linked to NHS hospitals were associated with three deaths. And now, it’s happened again, this time via ready meals.

Symptoms of Listeriosis

Signs usually show up a few days after eating contaminated food and often mimic a common flu: high fever, muscle aches, chills, nausea, vomiting and diarrhoea. For most people, these pass within a few days. But when they don’t, or if you’re pregnant or immunocompromised, the infection can spread to the nervous system, leading to potentially fatal complications like meningitis.

Not Just ‘Old People’s Illness’

While the recent victims of the outbreak were aged between 68 and 89, age isn’t the only factor that increases vulnerability. Babies can be affected too, often showing signs like irritability or poor feeding. Pregnant women may notice abdominal pain or reduced foetal movement. And anyone with a weakened immune system, from chemotherapy patients to people living with diabetes, is at risk of severe illness. So while most of us might brush off a bit of food poisoning, listeriosis is in a league of its own.

Supermarkets in Panic Mode

After the tragic death in Ireland, supermarkets scrambled to recall dozens of ready-to-eat products. Ballymaguire Foods' dishes, commonly stocked in fridges across Tesco and Aldi, were swiftly pulled from shelves. Meanwhile, the Food Standards Agency (FSA) issued urgent notices recalling a broad range of chilled desserts like mousses, yoghurts and cream rolls, many of which had been supplied to NHS hospitals and care homes.

Why the panic? Because once listeria is detected in a production batch, it signals a potential contamination risk across all connected products. And in places like hospitals or care homes, even a small mistake can be deadly.

How to Avoid Listeriosis And Keep Your Fridge From Becoming a Biohazard

Most listeriosis cases are preventable. The bacteria thrives in cold environments, especially on ready-to-eat chilled foods that aren’t reheated before consumption. But with a few smart hygiene and storage habits, you can dramatically cut down your risk.

Here’s what experts recommend:

• Keep your fridge at 5 degrees Celsius or below. Anything higher, and you’re basically inviting bacteria to the party.
• Don’t let ready meals loiter. Eat them within four hours of removing them from the fridge.
• Check those use-by dates. Not ‘best before’; we’re talking the real deadline. Don’t mess around with expired food.
• Separate raw and ready-to-eat items. Think of it as a hygiene social distancing rule.
• Cook properly. Even if the packaging says ‘microwave for 3 minutes’, make sure the food is steaming hot all the way through.
• Wash your hands thoroughly. Use soap and scrub well, especially after handling raw food.
• Use food quickly after opening. If the label says ‘consume within two days’, take it seriously.