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Robert F Kennedy Jr, who is the United States Secretary of Health and Human Services HHS, has remained on top of the news headlines with his never-ending controversial comments. In another controversial proposal, he has asked to let bird flu naturally spread through poultry farms. This has raised alarms among scientists who say this move could be inhumane and dangerous.
He suggested that instead of culling the birds, the farmers should allow the virus to run its course through the flock to identify naturally immune birds. He told Fox News, "We can identify the birds and preserve the birds that are immune to it."
While Kennedy has no direct control over the farms, the Agriculture Secretary Brooke Rollins has also taken an interest in testing this idea. He told the CBS, "There are some farmers that are out there that are willing to really try this on a pilot as we build the safe perimeter around them to see if there is a way forward with immunity."
However, experts, including the veterinary experts say that this could in fact backfire. Dr Gail Hansen, who was a former state veterinarian for Kansas told The New York Times, "that's a really terrible idea for any one of a number of reasons."
Bird flu in the US has affected more than 166 million birds since 2022. At such a rate, experts warn that allowing the virus to run through the flock would increase the risk of it mutating. However, the administration thinks otherwise, "Culling puts people at the highest risk of exposure, which is why Secretary Kennedy and N.I.H. want to limit culling activities. Culling is not the solution. Strong biosecurity is,” said Emily Hilliard to The Times, who is the deputy press secretary at the Department of Health and Human Services.
Experts across however have suggested against it. They have even predicted that if this is allowed, it would kill 100% of all turkeys and chicken. The reason is because the way birds are raised now do not have a lot of genetic variability. They are all basically the same bird. However, what Kennedy had suggested was for poultry to have a natural immunity, almost like the concept of "herd immunity". However, it cannot be the case when birds do not have a diverse genetics.
To give a ray of hope, scientists have now created a handheld sensor that can quickly detect H5N1 in the air, which could potentially stop the outbreak before they spread.
The findings of this handheld sensor is published in journal ACS Sensors, which noted it to be a low-cost, highly sensitive and workable sensor.
This research was led by Rajan Chakrabarty, who is the leader of the Aerosol Interdisciplinary Research(AIR) group at Washington University. His team developed the sensor using electrochemical capacitive biosensor (ECB) technology. The ECB features a thin network of nanocrystals and graphene oxide, with special probes that attach to bird flu particles.
This is a built-in-air sampler, which collects airborne virus droplets and turns them into a liquid sample. When the virus binds to the sensor, it changes the device's ability to hold electrical charge. This allows the scientists to measure virus levels.
In lab tests, the ECB sensor detected the H5N1 virus within five minutes. It was also sensitive enough to identify 95 viral copies per 35 cubic feet of air. This is a level that researchers say should be "sensitive enough to detect the presence of H5N1 below the virus' infectious dose."
Read more on Bird Flu, here.
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The uncertainty around the Novavax's COVID-19 vaccine has been exacerbated by the Trump administration. The new government has imposed new requirements on the nation's only traditional protein-based vaccine. These new requirements have led to many confusions about vaccine updates, including other vaccines too, which await approval.
Novavax is the maker of the protein-based COVID-19 vaccine, which was on track to receive full approval from the US Food and Drug Administration (FDA) by April 1. However, the approval process was paused because of Dr Sara Brenner, the FDA's acting commissioner. The reason for delay has raised many questions about the interference, including political, especially after Dr Peter Marks, FDA's longtime vaccine chief had left following disagreements with Health Secretary Robert F Kennedy Jr. These events have further led to the apprehensions of uncertainty regarding the vaccine's future.
As of now, Novavax's vaccine is only authorized for emergency use. Unlike mRNA vaccines form Pfizer and Moderna, which have full approval, the Novavax vaccine holds the EUA or the Emergency Use Authorization, which allows it to be distributed during public health emergencies. However, once the emergency ends, the FDA can remove these vaccines from market unless full approval is granted.
The FDA had initially planned to approve Novavax's vaccine by its April 1 target date. However, sources familiar with the situation revealed that Trump appointees influenced the delay. Since then, Novavax has been in discussions with the FDA to determine additional requirements for approval. In the meantime, the FDA's recent comments have fueled concerns that Novavax’s vaccine may be treated as a “new product” due to its updates to match last year’s coronavirus strain. This would require new clinical trials, a process unlikely to be completed before the fall.
ALSO READ: Novavax Says FDA Approval Back on Track for Its COVID Vaccine
This approach to Novavax’s vaccine approval stands in stark contrast to the FDA’s treatment of the mRNA vaccines, where annual strain updates have been handled in a way similar to flu vaccines, requiring only small-scale tests to demonstrate the vaccine’s continued effectiveness against new strains. Dr. Paul Offit, a vaccine expert, argued that it would be unnecessary to treat these annual updates as “new products” requiring full trials, as long as the updated vaccines show that they produce protective antibody levels.
Of course Robert F Kennedy Jr will have a role to play, being the Health Secretary, and a known vaccine skeptic. Despite claiming in recent speeches that he is not anti-vaccine, Kennedy’s past associations with anti-vaccine groups have raised alarms. His nonprofit, Children’s Health Defense, has been involved in campaigns questioning vaccine safety, and Kennedy himself has made public statements suggesting that vaccines can cause autism—a long-debunked claim.
His actions have also contributed to the uncertainty that surrounds the Novavax's approval today and the overall direction of US vaccine policies.
What sets Novavax apart from other COVID-19 vaccines is its traditional approach. While Pfizer and Moderna’s mRNA vaccines use genetic instructions to create a temporary version of the virus’ spike protein, Novavax’s vaccine contains lab-grown copies of the spike protein itself. This approach has been used for decades in vaccines for diseases like hepatitis B and shingles, making it a more familiar method for people who may be hesitant about mRNA vaccines.
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Danish multinational pharmaceutical company Novo Nordisk has launched Wegovy in Thailand, marking the entry of its hugely popular weight loss drug in Southeast Asian market. First launched in 2021, Wegovy helped make Novo Nordisk Europe's most valuable listed company until recently, worth $615 billion at its peak. Wegovy is a semaglutide shot, which means that it is a GLP-1 receptor agonist.
"We actually received the Thai FDA approval already in 2023," said Enrico Canal Bruland, vice president and general manager of Novo's Thai subsidiary. He noted that Novo was making Wegovy available in Thailand ahead of rival Eli Lilly's Zepbound. Wegovy is currently available for prescription in private hospitals around the country and will be available soon in public hospitals. Notably, Bruland declined to provide details on Wegovy's pricing in Thailand, which has a population of around 66 million, or Novo Nordisk's plans for expansion into other Southeast Asian markets.
Notably, the most popular GLP-1 agonist Ozempic was also created by Novo Nordisk. Earlier this month, the pharma giant expanded its research in the field diabetes and weight loss drug and announced that its diabetes pill, Rybelsus, demonstrated cardiovascular benefits in a late-stage trial. The findings pave the way for the medication to become a new treatment option for people living with both diabetes and heart disease.
How Do Semaglutides Work?
Semglutide is the synthetic version of GLP-1—a natural hormone produced in the intestines that regulates blood sugar, appetite, and digestion. Now, every time you eat, your body produces various hormones, including GLP-1. These are called Post nutrition hormones, and help you absorb the energy you just consumed.
GLP-1 travels to your pancreas, prompting it to produce insulin. It also travels to the hypothalamus in your brain, which gives you the feeling of being full or satiated. Ozempic imitates this hormone, thereby, silencing the food chatter in the brain. Interestingly, for some people this food chatter is really quiet ( people with low appetite) and for others it is an outbrurst, (people who generally binge eat.) So with Ozempic, silencing this self-talk in the brain, people tend to lose their appetite and eventually weight.
However, it is important to note that losing weight includes not just fat but muscle as well. Losing too much muscle can lead to reduced strength and a shorter life span. Notably, records show that most people who start taking them stop it at 12 weeks; therefore, it is important for some but not for others.
Notably, last month, US pharma major Eli Lilly launched the obesity management drug Mounjaro in India at one-fifth of the US price. The company rolled out the drug in a single-dose vial following the marketing authorisation from the Central Drugs Standard Control Organization (CDSCO). It has been priced at Rs 3,500 for a 2.5 mg vial and Rs 4,375 for a 5 mg vial. "It is a first-of-its-kind treatment for obesity, overweight, and type 2 diabetes that activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors," the company said.
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One moment, Dr Cornelius Sullivan was focused on a patient during surgery, and the next moment, he woke up in ambulance, headed to the emergency room.
According to the American Society of Anesthesiologists (ASA), Dr Sullivan had struck his head on a monitor that had been moved behind him in a surgery center. This serious accident had resulted in a two-night hospital stay and kept him away from work for weeks. However, this is not the first time he had suffered a work-related injury. This is, in fact, the third time this has happened, noted ASA.
These injuries are often called "boom strikes". These occur when anesthesiologists accidentally bump into operating room (OR) equipment that is mounted on fixed or moveable arms. These could be monitors, lights, or screens.
While any OR staff member could be hurt this way, anesthesiologists are particularly more vulnerable to such injuries. Their work requires them to operate in tight, also, often crowded spaces. It also requires them to move quickly during emergencies, which further increases the risk of collision with equipment.
As per ASA, the risk of boom strikes have been on the rise. This is also because of an increase in sophisticated equipment being added to operating rooms and surgeries are also now performed in much smaller spaces.
As per a survey conducted by the organization, it was found that more than half of anesthesiologists reported experiencing at least one work-related injury, including head injuries. These numbers have highlighted the growing concern over physical safety in an already demanding and high-pressure environment.
In response to these alarming findings, the ASA has issued a new Statement on Anesthesiologist Head Injuries in Anesthetizing Locations.
The statement formally recognizes boom strikes as a serious occupational hazard and even a potential medical emergency — especially dangerous during outpatient procedures or in cases where no backup anesthesiologist is immediately available to take over patient care.
Dr. Mary Ann Vann, chair of ASA's Ad Hoc Committee on the Physical Demands of Anesthesiologists, also experienced a work-related head injury. Drawing from personal experience, Dr. Vann helped develop the new safety recommendations, aimed at preventing such incidents.
The ASA outlined several measures to reduce the risk of head injuries among anesthesiologists, including:
Holding Regular Safety Meetings: OR teams should meet frequently to discuss safety concerns and review past incidents.
Creating Safety Teams: Special teams should be tasked with reviewing and tracking reports of boom strikes to identify patterns and solutions.
Involving Anesthesia Staff in Room Planning: Clinical anesthesia personnel should have a voice when designing or rearranging procedure rooms to ensure equipment placement considers movement and space needs.
Tracking Head Injuries: Systematic documentation of head injuries can help health systems better understand causes and outcomes, leading to more informed prevention strategies.
The ASA emphasized that head injuries in the OR are not just minor accidents but events that can have serious consequences for patient safety and anesthesiologists’ health.
By implementing the new guidelines and raising awareness, the ASA hopes to make operating rooms safer environments for all medical professionals — and ensure that anesthesiologists can continue their vital work without unnecessary risk.
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