With the patent on semaglutide expiring today in India, NATCO Pharma has become the first drugmaker to launch the generic version of the weight-loss drug in the country. NATCO Pharma’s generic semaglutide injection prices start at INR 1,290 per month. “NATCO is the first company to offer generic semaglutide in multi-dose vials with customized syringes… It is the most affordable GLP-1 currently in the Indian market as it is approximately 70 percent cheaper in cost than the pen device and 90 percent cheaper than the price of the innovator’s brand,” the Hyderabad-based company said, in a statement. The company had received approval from the Central Drugs Standard Control Organization (CDSCO) in February 2026 to manufacture and market the drug, after a clinical comparison study.Semaglutide works by targeting key areas of the brain involved in appetite regulation and food intake. It reduces hunger, improves satiety, and cuts down food cravings, eventually inducing weight loss.It also improves insulin resistance and has a beneficial effect on the reduction of cardiometabolic events and risk factors. NATCO's Semaglutide Drugs NATCO's semaglutide drugs will be sold under brand names SEMANAT and SEMAFULL in multi-dose vial formats. It will be priced:INR 1,290 per month for the 2 mg/1.5 ml and 4 mg/3 ml variants, INR 1,750 for the 8 mg/3 ml dose.In addition, NATCO is also expected to launch its pen device in April. It will be priced at INR 4,000 for 2 mg/1.5ml, INR 4,200 for 4 mg/3 ml, INR 4,500 per month for 8 mg/3 ml. In comparison, Novo Nordisk's Ozempic and Wegovy in pen devices cost INR 8,800 and INR 10,850, respectively, per month for the starting doses. NATCO has also signed a distribution partnership with Eris Lifesciences to co-market its therapy in India. Other Generic VersionsSeparately, Eris has also announced its plans to launch a multi-dose vial under the brand name "Sundae". The company's generics will be at the same price for the type-2 diabetes indication. Sun Pharmaceutical Industries, Dr. Reddy’s Laboratories, and Zydus Lifesciences are also expected to introduce their versions of semaglutide on Saturday. Others in the pipeline include Alkem Laboratories, Torrent Pharmaceuticals, and MSN Laboratories. With intense competition, analysts believe around 50 branded semaglutide generics will enter the Indian market within months, BBC reported. Calling it a potential "magic-pill moment" for India, investment bank Jefferies predicted that the semaglutide market in the country could reach $1bn domestically.Also read: CDSCO threatens action against pharma companies for promoting GLP-1 weight-loss drugs End Of Novo Nordisk’s PatentsIn January this year, Canada became the first country to lose patent protection for semaglutide. However, the country's health regulator hasn’t approved any generics so far. Novo Nordisk is expected to lose the patent in 10 more countries, including Brazil, China, South Africa, Turkey, and Canada, by the end of 2026.In view of losing patent, Novo Nordisk recently cut prices for Wegovy in India. The company also launched its blockbuster brand Ozempic in December.