Five years after COVID-19 outbreak, China has a new health concern: the sudden outbreak of HMPV in the country. According to sources, the viral infection is growing at an exponential rate, thereby overloading health facilities and crematories, all of which could be seen online through social media posts and videos that have surfaced on the viral network. Amid these concerns, other respiratory illnesses like influenza A, Mycoplasma pneumoniae, and COVID-19 are said to be also circulating simultaneously with the same conditions, making a heavy strain on the health services. As of this, neither the Chinese government nor the WHO has given official warnings or declared any emergency in these cases.

To combat this upsurge, Chinese health authorities have implemented a pilot system to track cases of pneumonia with unknown origins. This new initiative was launched by China's disease control agency to increase preparedness for respiratory outbreaks during the winter months, a drastic change from the way the nation responded to the COVID-19 pandemic.

This outbreak has affected mostly vulnerable populations, including children whose immune systems are still developing and elderly persons who have a pre-existing respiratory disease. The symptoms of HMPV tend to be those of a cold or flu-like illness, characterized by fever, coughing, and nasal congestion. In some cases, these infections can develop into bronchitis or pneumonia, which significantly increase the risk of complications for individuals with diseases like asthma or COPD.

Despite the similarities to COVID, this virus is very different and was infact identified way back in 2001 and it has been circulating in the entire world since many years. HMPV is not a new virus, and far less worrisome.

Read for HMPV Virus Symptoms , Causes , Treatment and Prevention

What is Human Metapneumovirus (HMPV)?

First identified in the Netherlands in 2001, human metapneumovirus is a respiratory RNA virus within the Paramyxoviridae family. It is a seasonal virus, most actively circulating during the winter and spring seasons. This virus is responsible for one of the most significant causes of hospitalization in the acute respiratory infection (ARI) category among young children, after RSV.

Research indicates that almost all children older than five years have been infected with HMPV, although the immunity developed against subsequent infections is partial. Though it is more of a cold-season disease, cases have been reported throughout the year, with the prevalence of the disease fluctuating every year.

Is HMPV Contagious?

HMPV is commonly spread through contaminated respiratory droplets from infected person to person often by cough, sneeze, or the transfer of aerosolized microorganisms from touch of contaminated fingers on doorknobs and toys. Similar to RSV and influenza within the United States, HMPV follows an annual peak or surge that mostly occurs during winters and springs in many parts.

Human metapneumovirus Symptoms

HMPV infections are highly similar to some of the classic symptoms of 'common cold', they include:

• Fever
• Coughing
• Nasal congestion
• Runny nose
• Sore throat
• Nausea and vomiting

Most symptoms of bronchiolitis go away in a few days. However, more severe cases may lead to complications such as bronchitis or pneumonia, or even life-threatening conditions. Sometimes, young children may suffer from severe bronchiolitis that can be fatal.

Who Is Most at Risk?

While HMPV can affect all age groups, it significantly affects the following:

Those with immature immune systems are highly susceptible to developing severe complications like bronchiolitis or pneumonia.

Individuals with conditions such as COPD, asthma, or pulmonary fibrosis have a higher chance of developing serious symptoms.

People who are undergoing chemotherapy or have recently received an organ transplant are highly vulnerable.

Also Read: What Is Disease X? Preparing For The Next Global Threat

How Is HMPV Diagnosed and Treated?

Diagnosis of HMPV is usually based on a physical examination, patient history, and laboratory tests. In severe cases, advanced diagnostic techniques, like bronchoscopy, are applied to confirm the virus. Treatment is usually symptomatic as there are no specific antiviral therapies or vaccines for HMPV. Some treatments according to the American Lung Association include:

- Over-the-counter medications for relieving fever and pain.

- Inhalers or corticosteroids to control wheezing or harsh coughing.

- Prednisone is the prescription medication only in extreme conditions.

Human Metapneumovirus (HMPV) vs. COVID-19 HMPV and COVID-19 have similarities in their transmission modes and respiratory symptoms. HMPV is a seasonal virus, mostly surfacing during winter and spring. COVID-19, on the other hand, is a year-round virus, with emerging variants.

Surprisingly, the number of cases for other respiratory viruses, such as HMPV, rose drastically during this time as restrictions against COVID-19 relaxed. Scientific evidence shows that during the lockdowns, fewer instances of contact with regular viruses resulted in a vulnerability to them, including HMPV, after restrictions eased.

Is HMPV Preventable?

The only prevention from the virus, however is to avoid contracting it in the first place, particularly for high-risk populations. Dr. Sunil Kumar K, Lead Consultant - Interventional Pulmonology explains, "Preventive strategies include maintaining good hand hygiene, wearing masks in crowded places, and practicing respiratory etiquette, such as covering coughs and sneezes. It's also advisable to avoid close contact with individuals exhibiting respiratory symptoms. Given the absence of a vaccine, these measures are crucial in controlling the spread of the virus."

"While HMPV shares transmission characteristics with COVID-19, such as spread through respiratory droplets, it is generally less severe. However, co-circulation with other respiratory pathogens, including influenza and Mycoplasma pneumonia, as reported in China, can complicate clinical outcomes and pose additional challenges to public health systems.

Continuous surveillance and public awareness are vital in managing this outbreak. Learning from the COVID-19 pandemic, early detection, transparent communication, and adherence to preventive measures are key to mitigating the impact of HMPV and safeguarding public health."

Individuals with chronic conditions of the respiratory system should keep their environment, very clean and shy away from contaminated areas.

As respiratory illnesses continue to rise in China, health experts stress the importance of proactive measures and public awareness. While HMPV is typically mild, its potential to cause severe complications in vulnerable groups underscores the need for vigilance. For now, a combination of symptom management, robust healthcare systems, and effective monitoring initiatives will be critical in managing this growing health challenge.

Dr. Sunil Kumar K is the Lead Consultant - Interventional Pulmonology at Aster CMI Hospital, Bangalore in India

Human Metapneumovirus and Other Respiratory Viral Infections during Pregnancy and Birth, Nepal. Emerg Infect Dis. 2017

Human metapneumovirus and respiratory syncytial virus: subtle differences but comparable severity. Infect Dis Rep. 2010

Human Metapneumovirus (hMPV). American Lung Association.

As a part of World Immunization Week, which is observed from April 24 to 30, to promote the life-saving power of immunization, notes the World Health Organization (WHO), India has launched a week-long campaign to vaccinate 100% of children against measles and rubella. This is a move described as crucial to country's goal of eliminating the two viral diseases by 2026, noted Union Health Minister JP Nadda.

As per WHO, this week aims to promote the power of immunization to protect people of all ages against vaccine-preventable diseases. Vaccines are one of humanity's greatest achievements, notes WHO. Since 1974, they have saved 150 million lives.

As per India's aim, Nadda suggests that health workers must not only ensure complete vaccination overage, but also remain vigilant through robust disease surveillance. “Measles is very contagious. Even a single case must be treated as a warning signal. We have to cover immunity gaps and ensure no child is left behind,” he said.

As per WHO, India has reported 4,388 cases of measles and 527 cases of rubella so fat this year.

What Are Measles And Rubella?

Measles is a highly contagious viral infection marked by symptoms such as high fever, rash, cough, red eyes, muscle pain, and headache. Though often seen as a childhood illness, measles can lead to severe complications, including pneumonia, brain swelling (encephalitis), and even death, particularly in malnourished children and those with weakened immune systems.

Rubella, caused by a different virus, typically results in milder symptoms in children and adults. However, it poses a grave risk to pregnant women. Infection during pregnancy, particularly in the first trimester, can cause miscarriage, stillbirth, or congenital rubella syndrome (CRS) — a condition leading to serious birth defects like heart problems, deafness, and developmental delays. According to WHO, rubella control is essential for reducing infant mortality and morbidity.

History of Measles and Rubella Vaccination In India

India has a long battle with measles, which had accounted for a significant portion of global measle deaths. In order to tackle this, the country introduced measles vaccination in 1985, under the Universal Immunisation Programme. However, rubella vaccination lagged behind until the Measles-Rubella (MR) vaccination campaign was launched in 2017.

This massive drive aimed to immunize 410 million children between 9 months and 15 years of age, marking one of the largest vaccination campaigns in the world, according to the Ministry of Health and Family Welfare. Post-campaign, the MR vaccine was incorporated into India’s routine immunization schedule, with two doses given between 9–12 months and 16–24 months of age.

Since measles and rubella are both highly contagious, health authorities say that achieving very high vaccination coverage — over 95% — is critical for creating herd immunity and stopping outbreaks.

Is India Close To Its Goal?

Health Ministry data shows promising progress: in 2024–25, 93.7% of children received the first MR vaccine dose, while 92.2% received the second. However, to achieve disease elimination, India needs to push these numbers above 95% consistently across all regions.

Highlighting the importance of full coverage, Nadda called upon public representatives to actively support the campaign and spread awareness, particularly in hard-to-reach areas.

Despite progress, India faced a significant measles outbreak in 2023. The country was among 57 globally that saw major outbreaks after routine immunization services were disrupted during the Covid-19 pandemic. In 2023 alone, India reported 68,794 cases of measles and 2,930 cases of rubella.

Responding to the surge, the government intensified supplementary immunization activities, targeting areas where outbreaks occurred. The impact is visible: measles cases dropped by 73% and rubella by 17% in 2024 compared to the previous year.

With sustained efforts, India is now on a strong path towards achieving measles and rubella elimination by 2026.

Note: The data is taken from World Health Organization and Ministry of Health and Family Welfare, Government of India.

Fatty liver disease, now called metabolic dysfunction-associated steatotic liver disease (MASLD), happens when extra fat builds up in liver cells without alcohol being the cause. Normally, the liver contains some fat, but if more than 5–10% of the liver’s weight is fat, it is considered a fatty liver. In its advanced stage, MASLD can develop into metabolic dysfunction-associated steatohepatitis (MASH), causing swelling and serious damage to the liver. Alarmingly, MASLD affects about 100 million people in the United States, including a growing number of children.

The disease often develops silently. Many people do not experience symptoms early on, but if it worsens, signs like fatigue, abdominal pain, jaundice, swelling, and even mental confusion may occur. Risk factors include obesity, diabetes, high cholesterol, rapid weight loss, poor eating habits, and certain medications.

A Breakthrough in Early Prediction

A new study offers hope for earlier detection. Researchers, led by Dr. Shiyi Yu from Guangdong Provincial People's Hospital in China, have developed a blood test that looks for five specific plasma proteins to predict MASLD years before symptoms show up. The findings are set to be presented at the Digestive Diseases Week meeting in San Diego.

The test was shown to be 84% accurate at predicting fatty liver disease five years in advance and 76% accurate at predicting it 16 years ahead of diagnosis. When additional factors like body mass index (BMI) and daily exercise habits were added, the prediction accuracy improved even more—over 90% at five years and 82% at 16 years.

This model was tested on two different groups—participants from the UK Biobank (over 50,000 people) and a separate group in China—showing promising results across diverse populations.

Why Early Detection Matters

Fatty liver disease not only damages the liver but also increases the risk of early death—primarily from cardiovascular diseases (CVD) rather than liver failure itself. The connection between MASLD and heart disease is strong, as both share causes like high blood sugar, high triglycerides, and obesity. That is why early diagnosis is crucial—not just to protect the liver, but also to manage the risk of heart disease.

Early identification through a simple blood test could lead to earlier lifestyle changes, medical monitoring, and interventions that can prevent serious complications like cirrhosis or heart attacks.

What You Can Do

Currently, there is no approved medication for MASLD. Treatment mainly involves:

• Maintaining a healthy weight through diet and exercise
• Controlling diabetes and cholesterol levels
• Avoiding alcohol
• Following medical advice if already diagnosed

Preventive steps include eating a balanced diet rich in lean proteins, fruits, vegetables, whole grains, and healthy oils, being physically active, and avoiding unnecessary medications.

Although the findings are considered preliminary until published in a peer-reviewed journal, this research marks a major advancement. It shows that a simple blood test could soon help millions of people know their risk decades in advance, giving them a chance to change the course of the disease before it's too late.

As the United States experiences the worst measles outbreak in over a decade with nearly 900 reported cases across 29 states, including deaths of two children, public understanding of the disease and its prevention strategy have been highly misunderstood due to political divide. The outbreak began in West Texas and has now spread widely. This highlights not only the persistent threat of measles but also the growing influence of vaccine misinformation, which have been fueled by political figures.

Why Is There A Resurgence of Preventable Diseases?

Measles, a highly contagious viral disease, had been largely controlled in the U.S. thanks to the widespread use of the measles, mumps, and rubella (MMR) vaccine. However, gaps in vaccination coverage have led to a resurgence. The current outbreak, centered in Texas but extending to almost 30 states, has alarmed public health officials. Two young girls who were otherwise healthy have died as a result of measles complications.

The disease is known for its rapid transmission. A single case can lead to significant spread if vaccination rates in a community fall below the 95% threshold needed for herd immunity. Children are particularly vulnerable; although the first dose of the MMR vaccine is typically administered at 12 months, increased parental concern has led some to seek earlier vaccination during the outbreak.

The Politics Of Vaccine

As per a new survey by KKF, a nonprofit health information group, only one-third of Republican-leaning parents were aware of the current measles outbreak. This was in comparison with the two-thirds of aware Democratic parents. The survey also found and 1 in 5 Republicans believes that measles vaccine is more dangerous than the diseases itself, this is double the rate of Democrats.

These gaps in perception are not new but are deepening. About 35% of Republicans surveyed believe the discredited theory that the MMR vaccine is linked to autism—a belief held by just 10% of Democrats. While belief in this theory has not increased significantly, public awareness of the claim has grown, reflecting the impact of persistent misinformation.

Adding to the confusion is Health and Human Services Secretary Robert F. Kennedy Jr., who has long been associated with anti-vaccine rhetoric. Since taking office, he has supported an investigation into environmental contributors to autism and has floated unproven theories, such as vitamin A being a preventative measure against measles. These statements, while not outright opposing vaccines, muddy public understanding and can discourage immunization.

At a time when clear public health messaging is critical, conflicting remarks from top officials are exacerbating distrust. Advocacy organizations like Immunize.org and The Immunization Partnership warn that such mixed messaging, especially when it originates from high-ranking leaders, undermines public confidence in vaccines.

In southern states like Texas, Louisiana, Arkansas, and Oklahoma, anti-vaccine activism has gained traction within state legislatures. Studies show that even lawmakers with medical backgrounds have not always supported public health measures, often influenced by political considerations and public pressure. Testimony from vaccine opponents at legislative hearings further amplifies misinformation, making it more difficult for facts to gain traction.

Meanwhile, healthcare providers are seeing the consequences firsthand. In California, where a 2014–15 outbreak began at Disneyland, pediatricians have treated severely ill children and taken stricter stances on accepting unvaccinated patients. These outbreaks serve as a stark reminder that the threat of measles is real and recurring.