Scott Swift, 73, pop singer Taylor Swift's dad just underwent a quintuple bypass surgery, revealed Taylor during one of the episodes of Travis Kelce and Jason Kelce's New Heights podcast.

She also shared that she had moved in with her dad earlier this year to take care of him for a speedy recovery. She noted that her father has been full of gratitude after the surgery. "He was the loveliest patient ever. He just kept saying thank you over and over again."

Why Did Scott Swift Need A Surgery?

Taylor called the surgery "really intense" and said that her dad's heart always had a healthy ECG or electrocardiogram. He also ensures to get it every year to remain a step ahead of any physical ailments. However, five hard blockages were found in his heart during a resting stress test.

"He's been telling all his friends, 'You need to get the stress test,' because that's what's actually preventative. If you can find that earlier, you don't have to have a bypass surgery," she said.

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Taylor confirmed that her father is doing "incredibly well" and that his humor has helped him go through during the hard times. It still is very much intact in him.

She shares that he did not know how many blockages he's had, on being told that he underwent a quintuple bypass, which means five blockages, he also joked about it. "Well, you see, I come from a very competitive family," he told Taylor.

What Is A Stress Test?

As per the National Institute of Health (NIH), US, it is a form of physical test that typically utilizes electrocardiography along with blood pressure monitoring and exercise, which involves a treadmill or bicycle.

However, in a resting stress test, the assessment happens when the heart muscle is at rest after stress. This stress helps in identifying areas of reduced blood flow like ischemia or damage to the heart muscle, which can indicate conditions like coronary artery disease.

The test involves injecting a radioactive tracer into the bloodstream, then using a special camera to take images of the heart at rest and after stress.

What Is A Bypass Surgery?

As per Johns Hopkins Medicine, bypass surgery or coronary artery bypass graft surgery (CABG) is a procedure used to treat coronary artery disease. Coronary artery disease (CAD) is the narrowing of the coronary arteries. These are the blood vessels that supply oxygen and nutrients to the heart muscle. CAD is caused by a build-up of fatty material within the walls of the arteries. This buildup narrows the inside of the arteries, limiting the supply of oxygen-rich blood to the heart muscle.

How Does It Work?

One way to treat the blocked or narrowed arteries is to bypass the blocked portion of the coronary artery with a piece of a healthy blood vessel from elsewhere in your body. Blood vessels, or grafts, used for the bypass procedure may be pieces of a vein from your leg or an artery in your chest. An artery from your wrist may also be used.

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This surgery is done to treat a blockage or narrowing of one or more of the coronary arteries. It can restore the blood supply to your heart muscle when nonsurgical procedures are not a choice.

More Updates From The Swift Family

In addition to Scott, Taylor shared that her mom Andrea Swift, too, under a procedure. “My mom just got a new knee,” Taylor shared. “She’s doing great. She’s scampering around. We’re not quite at scampering yet, but she’s doing great.”

She noted that her parents are her best friends.

"It was actually one of the most special things that's ever happened to me, spending all that time with them this summer. You have those long talks that you don't have when it's a small, concentrated period of time.”

Nobel Peace Prize 2025: It was 1am at night, when Mary Brunkow's phone began to ring, assuming it to be a spam call, she put it on "do not disturb" and went back to sleep. Her husband too ignored the rings, only to be woken up along with their dog a few minutes later, when the Associated Press photographer showed up at their door. This is when Brunkow realized that she had won a Nobel Prize.

Brunkow along with two other scientists Fred Ramsdell and Shimon Sakaguchi had won the Nobel Prize "for their discoveries concerning peripheral immune tolerance".

What Is " peripheral immune tolerance"?

It refers to the mechanisms by which the immune system prevents self-reactive immune cells, especially the T-cells from attacking healthy tissues once they are already in the body's circulation.

The three are award for their work that revealed the existence and function of these special class of T-cell, called the regulatory T-cells, which act as brakes on immune responses, preventing autoreactivity. They also discovered the gene FOXP3, whose proper function is essential to the development and operation of regulatory T-cells. Their discovery revealed that mutation in FOXP3 genes is what leads to serious autoimmune disorders.

How Did The Discovery Happen?

Long before FOXP3, Sakaguchi, who is a professor at Osaka University in Japan, resurrected and rigorously defined the concept of regulatory T cells, also called Tregs. In 1995, he published work that showed that a subset of T-cells marked by CD25 along with CD4 could suppress autoimmune responses in mice. Those cells would be later called as the regulatory T-cell. It was his discovery which became the "brake" the immune system needed.

Why Does This Discovery Matter?

Before Sakaguchi's work, the existence of regulatory T-cells was speculative, even controversial. The idea was dismissed because the evidence was murky. His work also opened the possibility that one day we may enhance regulatory T-cell functions in autoimmune diseases or inhibit it in cancer settings.

What Did Brunkow and Ramsdell Do?

While Sakaguchi defined the Treg population, Brunkow and Ramsdell filled the gap by discovering FOXP3, the gene whose expression is necessary for Treg development.

They studied that in mice, a peculiar strain known as "scurfy" mice, spontaneously developed lethal autoimmunity, which was manifested by scaly, flaky skin, enlarged lymph nodes and spleens, and early death. They showed that the scurfy phenotype is caused by a mutation on the X chromosome in a previously unknown gene which they named FOXP3.

Their discovery also showed that in humans, a rare autoimmune syndrome called IPEX, which is characterized by immune dysregulation, polyedendocrinopathy, entropathy, X-linked inheritance is caused by mutations in the human equivalent, FOXP3. They thus, directly connected the mouse mutation and human disease that proved that FOXP3 is central to immune self-tolerance.

Without functional FOXP3, regulatory T-cells fail to form or function, and immune system launches damaging attacks on normal tissues.

What Comes Next?

Their discovery is important as it can be used to treat autoimmune diseases like Type 1 diabetes, systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, and many more.

The scope for cancer immunotherapy and tolerance during organ transplantation also broadens with the discovery. As with the FOXP3, it becomes possible to design therapies that block Treg suppression locally, enabling the immune system to better recognize and attack tumors. In terms of organ transplantation, with Tregs, it may become feasible to engineer Tregs that home to transplanted organs and locally suppress rejection.

The Nobel press release and news sources note that more than 200 clinical trials are already underway based on regulatory T cell / peripheral tolerance ideas.

A recent report from Santé publique France highlights a significant rise in suspected COVID-related visits to emergency departments across the country during the week of September 15–21, 2025 (week 37). Compared with the previous week (September 8–14, week 36), hospital visits linked to COVID increased by 43% among children under 15, with 156 additional visits, and by 29% among adults, with 224 more visits.

Cases among adults had already started climbing the week before. This surge comes as a new SARS-CoV-2 variant, nicknamed “Frankenstein,” becomes increasingly common in France. Here is everything you need to know about this variant, its symptoms, and how to protect yourself.

What Is the Frankenstein Variant?

According to the World Health Organization (WHO), this rise is associated with the emergence of a new variant called XFG. It is nicknamed “Frankenstein” because it is a recombinant, meaning it contains genetic material from two different COVID-19 subtypes, LF.7 and LP.8.1.2. The WHO has classified XFG as a variant under monitoring since June 25, 2025, and it is spreading in several countries worldwide. Current evidence suggests that the public health risk remains low, and approved COVID vaccines are expected to continue preventing severe disease and symptomatic infection. Countries in Southeast Asia have also reported increases in both new cases and hospitalisations in areas where XFG has been widely detected.

Although XFG appears to spread more easily than other variants, experts say it does not seem to cause more severe illness. “The vast majority of infections are mild and resolve within a few days with rest,” said Dr. Gérald Kierzek. Infectious disease specialist Anne-Claude Crémieux added that, so far, there are no signs the variant is more dangerous than previous strains.

Symptoms of the Frankenstein Variant

The symptoms of XFG are similar to those seen with previous COVID-19 variants and are generally mild, resembling a common cold. These may include:

• Sore throat
• Runny or congested nose
• Dry cough
• Fatigue and muscle aches
• Mild fever
• Loss of appetite

Why Is The Variant Called Frankenstein?

The nickname “Frankenstein” reflects the variant’s hybrid nature, as it combines genetic material from multiple COVID-19 subtypes.

Frankenstein Covid Variant: Preventing Infection and Managing Symptoms

There is no treatment specific to XFG, so care follows the same principles used for other COVID variants.

• Vaccination: Current COVID vaccines remain highly effective at preventing severe illness and hospitalisation, even if protection against infection may be slightly reduced.
• Symptom relief: Rest, hydration, fever reducers, and cough medicines can help manage mild symptoms.
• Protective measures: Wearing masks, maintaining hand hygiene, social distancing, and avoiding crowded places remain important.

Research on the Frankenstein variant is ongoing. Since the disease can affect individuals differently, taking personal precautions and consulting a doctor when symptoms appear remain essential.

The oral cholera vaccine Shanchol, made in Hyderabad and first developed by Shantha Biotechnics, has received World Health Organization (WHO) prequalification after its production was recently revived under new management. The clearance allows global procurement agencies such as UNICEF, Gavi, and PAHO to source the vaccine for countries where cholera continues to have a serious public health threat, according to GCBC Vaccines. With the approval in place, here’s a closer look at the vaccine, how it works, and why it matters.

Shanchol: What Is the Vaccine?

Dr. K.I. Varaprasad Reddy, founder of Shantha Biotechnics, said, “Shanchol was designed to be an affordable and accessible answer for countries that struggle with repeated cholera outbreaks. The WHO’s prequalification continues that mission.”

Shanchol is an oral, inactivated, bivalent cholera vaccine that protects against Vibrio cholerae, the bacteria responsible for the disease. The name itself is a brand term rather than an abbreviation.

How Does The Shanchol Vaccine Work?

Type of vaccine: Shanchol is a killed whole-cell vaccine, which means it contains dead cholera bacteria. These are used to train the immune system without causing infection. Being bivalent, it offers protection against the two major cholera strains, O1 and O139.

• Administration: The vaccine is taken by mouth and usually given in two doses for full protection.
• Mechanism: Once ingested, the vaccine activates the immune system in the gut, prompting it to produce antibodies that stop Vibrio cholerae from attaching to the intestinal lining. This prevents the infection from taking hold and causing illness.

Shanchol Vaccine: Why It Matters?

• WHO prequalification: The WHO’s approval confirms that Shanchol meets global standards for safety and effectiveness, making it eligible for international procurement.
• Part of global stockpile: It plays a key role in the world’s oral cholera vaccine stockpile, which supports emergency response efforts in regions hit by cholera outbreaks.
• Current use: Shanchol is widely used in mass immunization drives across cholera-prone and outbreak-affected regions.

Production Revival

Originally created by Shantha Biotechnics, the vaccine later came under Sanofi’s ownership, which eventually halted its production. Manufacturing has now resumed under GCBC Vaccines, part of the Gland Family Office. With WHO prequalification restored, Shanchol will once again be distributed globally to support vaccination programs.

The Role of Oral Cholera Vaccines

Oral cholera vaccines (OCVs) such as Shanchol and Dukoral are tools in preventing the spread of cholera, a severe diarrheal disease caused by Vibrio cholerae. Taken orally, they help trigger an immune response in the intestine that limits bacterial infection. These vaccines are especially valuable in areas with poor sanitation and limited access to clean water.

Vishy Chebrol, Executive Director of GCBC Vaccines, said the company’s priority is to ensure that vaccines reach the countries that need them most, affordably and consistently. “We are also working to bring more affordable and innovative vaccines to global markets, continuing Shantha’s legacy of improving access to life-saving immunization,” he added.

With WHO’s renewed approval, Shanchol, a bivalent, killed whole-cell oral cholera vaccine effective against Vibrio cholerae O1 and O139, will continue to be supplied worldwide to meet growing demand and support national immunization programmes.