A new long-term study has revealed a troubling health trend in the United States: the number of Americans living with both type 2 diabetes and high blood pressure has doubled over the last two decades, with 1 in 8 adults now affected. Even more concerning is the steep rise in mortality risk associated with this dual diagnosis—suggesting that the combo of these two chronic diseases may be deadlier than previously understood.

Published in the peer-reviewed journal Diabetes Care, the study spans nearly 20 years and highlights how a rapidly increasing population is living with multiple metabolic risk factors—a condition that significantly raises the odds of heart disease, stroke, kidney failure, and early death.

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Researchers at Columbia University's Mailman School of Public Health mined health information from close to 49,000 American adults who took part in the National Health and Nutrition Examination Survey from 1999 through 2018. The National Center for Health Statistics conducted the survey, which captures interviews, laboratory tests, and physical exams to measure the health of the country.

According to the study, only 6% of Americans in 1999 suffered from both type 2 diabetes and high blood pressure. By 2018, it had risen to 12%, or about 1 in 8 adults. Those with both conditions were more than twice as likely to die from any cause and three times more likely to die from heart disease than those with neither condition.

"Even having co-existing prediabetes and high blood pressure was linked to up to 19% greater risk of death," said lead researcher Dr. Nour Makarem, assistant professor of epidemiology at Columbia University.

This is important because it indicates that heightened risk begins even before someone officially qualifies by clinical criteria as having diabetes or hypertension.

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Why Type 2 Diabetes And High Blood Pressure Compound Health Risks?

Having either condition on its own—type 2 diabetes or high blood pressure—already raises one's risk for severe complications but when they occur together, their interaction in the cardiovascular system is much more destructive.

Approximately two out of three patients with type 2 diabetes have high blood pressure or are prescribed medication for it. Among individuals with both disease states, about 33% died over a median 9-year follow-up period.

For individuals with only one condition, the mortality rate remained at 20–22%, whereas individuals with neither condition suffered from a mere 6% fatality during the same period of time.

The research identified that in comparison with individuals with:

Hypertension alone, developing both conditions increased the risk for all-cause mortality by 66% as well as cardiovascular death by 54%.

Type 2 diabetes alone, but with both conditions, overall risk of death was 25% higher and greater than two-fold increased cardiovascular mortality.

Why Type 2 Diabetes and High Blood Pressure Pair so Deadly?

Both type 2 diabetes and high blood pressure are "silent killers." Alone, they tend to produce no discernible symptoms until complications—such as stroke, heart failure, or kidney damage—arise. Combined, however, they provide a deadly combination of cardiovascular stress.

Diabetes disables the body's ability to keep blood sugar in balance. High glucose levels destroy blood vessels and organs by repeated damage.

Hypertension makes the heart work harder to circulate blood, which hardens and weakens the arteries.

When both conditions occur together, this speeds up the deterioration of the arteries, kidneys, and heart, making heart attack, stroke, and end-stage renal disease requiring dialysis or transplantation more likely.

Early Warning Signs That Are Often Missed

Another significant takeaway of the research is that the danger of death starts even prior to a full-blown diagnosis. Prediabetic and high-blood-pressure persons—even if they are below diagnostic levels—had a 19% greater risk of mortality.

Although type 2 diabetes can quietly develop without apparent symptoms, there are some early warning signs that should never be overlooked—particularly if you're at risk. The sooner you detect diabetes, the less complicated it is to control and prevent long-term complications. Even slight symptoms deserve a chat with your doctor.

• One of the first and most indicative symptoms of high blood sugar is urinating more often, particularly at night. As blood glucose increases, the kidneys work around the clock to flush out the excess glucose. When they're unable to keep pace, glucose leaks into the urine, causing more frequent trips to the bathroom.

• Too much sugar in the urine not only impacts hydration—but also is a breeding ground for bacteria and yeast. This increases the likelihood of infections in the urinary tract and yeast infections, particularly in women. If you find that you have persistent infections that are difficult to clear, you might want to be tested.

• Another visible clue is the appearance of dark, velvety patches of skin, typically found in body folds like the neck, armpits, or groin. These areas may indicate insulin resistance—a common precursor to diabetes.

• If you’re eating regularly but still feel hungry all the time, your cells may not be properly absorbing glucose. As a result, your body stays in a constant state of seeking energy, driving persistent hunger.

• Ironically, even though you are hungrier, you may actually lose weight unexpectedly. Since there's not enough glucose flowing into cells, your body starts to break down muscle and fat for energy.

• This energy shortage also leads to constant fatigue and weakness. You could be tired, even with a good night's rest. Dehydration caused by frequent urination only adds to that pervasive fatigue.

• Another troubling symptom is blurred vision, which can appear and disappear. High blood glucose can harm the tiny blood vessels in the eyes, leading to more severe conditions—blindness, if not treated.

• Most people experience a tingling or numb feeling in their hands or feet. This is caused by nerve damage from years of high blood sugar levels. Refereed to as diabetic neuropathy, this can also result in long-term chronic pain or loss of sensation.

This result highlights the importance of early screening and proactive prevention measures, particularly for individuals in their 30s and 40s who are unaware they're at risk. The research also reignites debate around various forms of diabetes, many of which have different risks:

Type 1 Diabetes: Autoimmune condition in which the pancreas releases no insulin.

Type 2 Diabetes: A metabolic disorder in which the body fails to utilize insulin. Frequently associated with obesity, a diet lacking in nutritious foods, and physical inactivity.

Prediabetes: A silent diabetes precursor with no warning signs.

Gestational Diabetes: Appears during pregnancy and increases risk of type 2 diabetes in the future.

Of these, type 2 diabetes is the most common and can be directly associated with lifestyle modifications that are often possible.

This highlights the pressing need for public health approaches to prevent and manage these diseases and to halt these negative trends," Dr. Makarem stressed.

At present, approximately two-thirds of adults with diabetes have blood pressure above 130/80 mm Hg or are taking antihypertensive therapy.

Since most symptoms are mild or undetectable, screening is necessary on a regular basis. The American Diabetes Association suggests that all adults over the age of 45 should be screened for diabetes. If you are younger but have risk factors that include obesity, being inactive, having a poor diet, or a family history of diabetes, you need to be tested too.

Screening is typically a straightforward blood test. If normal, the ADA recommends repeat testing at three-year intervals to track changes.

As an ageing population, inactive lifestyles and obesity on the rise, the co-epidemic of diabetes and high blood pressure is set to expand unless there are systemic changes.

The COVID-19 pandemic may feel like a chapter we’re slowly closing, but the virus continues to evolve, reminding us that the story is far from over. A new variant of the virus, NB.1.8.1, has recently been confirmed in the United Kingdom and is steadily appearing in various parts of the world—including the United States, Australia, Thailand, and parts of Asia and North Africa. First detected in January 2025, the Omicron subvariant has now become a global phenomenon, leading health officials to release new advisories, especially for travelers.

NB.1.8.1 is a new sublineage of the Omicron family, which has been the leading group of SARS-CoV-2 variants for several years. While it initially appeared in genetic surveillance data at the beginning of 2025, confirmed cases began to emerge more noticeably by April. It has been officially declared by the World Health Organization (WHO) as a "variant under monitoring," noting its rising rate of detection and susceptibility to avoiding immunity elicited from past infections or vaccination.

Today, NB.1.8.1 accounts for around 10.7% of all sequenced infections worldwide. Seven confirmed cases have appeared in Northern Ireland alone in the UK, and experts are monitoring its spread very closely. Its increasing circulation quickly has also brought questions regarding its behavior, contagiousness, and—most particularly—its symptoms.

How Does NB.1.8.1 Spread?

Following virologists and evidence from GISAID, NB.1.8.1 could have an increased capacity to infect human cells more effectively compared to some of its Omicron ancestors. This doesn't always mean it is more severe, but it will make the variant more infectious, particularly in densely populated indoor environments or areas where immunity is low.

The WHO has underscored that variant dynamics have also changed significantly since the start of 2025. Previously prevalent strains such as XEC and LP.8.1 are now being replaced by NB.1.8.1, particularly in places such as China and Hong Kong where this subvariant has rapidly emerged as dominant.

What Makes NB.1.8.1 Symptoms Different?

Although most symptoms are similar to other COVID-19 strains, the distinguishing factor of NB.1.8.1 is that it is more likely to cause gastrointestinal symptoms. Evidence in the UK and forthcoming international data suggest an uptick in cases presenting with symptoms of:

• Diarrhea
• Constipation
• Nausea or vomiting
• Abdominal pain and bloating
• Heartburn

These symptoms, though not entirely novel to COVID-19, are increasingly being reported in NB.1.8.1 cases. This change is leading experts to encourage physicians and patients to be sensitive to digestive complaints that might otherwise be misdiagnosed as foodborne illness or a stomach bug.

Recognizing The Unusual Symptoms of NB.1.8.1

Besides gastrointestinal distress, the NB.1.8.1 variant may also exhibit a broad spectrum of respiratory and systemic symptoms:

• High temperature or chills
• Coughing that doesn't go away
• Breathing that is short
• Loss or change of smell and taste
• Sore throat
• Headache
• Aching of muscles
• Runny nose or congestion
• Fatigue
• Loss of appetite

Note that although the occurrence of uncommon gastrointestinal symptoms could be used to distinguish NB.1.8.1, the majority of cases still mimic typical presentations of COVID-19. Therefore, proper diagnosis via testing is still vital.

Is the New Variant More Dangerous?

To date, there is no indication that NB.1.8.1 causes more serious illness or greater hospitalization than other Omicron subvariants. Nevertheless, its efficiency in spreading and in exhibiting symptoms that will not necessarily lead to COVID testing is a variant to monitor.

Immunologists are most interested in how it has the ability to partially evade immunity, something which could cause more breakthrough infections within vaccinated or previously infected people.

What Are The Precautions Travelers Must Take?

For tourists, particularly to countries with an upsurge of NB.1.8.1 infections such as the US, Australia, Egypt, the Maldives, and Southeast Asia, caution is the word. Although there are no fresh travel restrictions or bans introduced, public health officials suggest a number of precautionary measures:

• Be aware of local COVID-19 guidelines at your destination.
• Bring lateral flow tests and masks, especially while moving about airports or using public transportation.
• Practise diligent hand hygiene and limit time in enclosed or crowded spaces.
• Consider COVID-specific travel insurance, covering cancellations or health emergencies abroad.
• Monitor your health and delay travel if symptomatic.
• Travelers from the UK, in particular, are being urged to remain alert and informed as NB.1.8.1 spreads in popular vacation destinations.

Even as COVID-19 has become part of the everyday background, NB.1.8.1 is a reminder that the virus remains in motion. For high-risk groups—the elderly or immunocompromised—the threat is still real, and so is the call for public health awareness.

NB.1.8.1 isn't seen as more fatal, but its spreading and uncharacteristic symptoms render it a virus that requires concern, not hysteria. It all comes down to being informed, being aware of symptoms, particularly those that may sense unusual and taking preventative health care when abroad or ill.

British pop star Jessie J—best known for her powerhouse vocals and unfiltered honesty recently took to Instagram to share her stage-one breast cancer diagnosis, fans everywhere were left both shocked and motivated. The 37-year-old singer-songwriter, born Jessica Cornish, announced the news in typical frankness, mixing vulnerability with as she explained the surgery she'd be having after performing at Capital's Summertime Ball at London's Wembley Stadium.

Though her confession highlights the psychological burden of battling cancer under the spotlight, it also brings attention to an important discussion: the early warning signs of breast cancer that women so often miss. As a global health epidemic that claims millions of lives each year, breast cancer is more than mere lumps. The initial symptoms are often silent, confused, or ignored—particularly by young women.

In her heartfelt video message, Jessie shared that she has been “in and out of tests” recently and ultimately received a diagnosis of early breast cancer. “Cancer sucks in any form,” she said, “but I’m holding on to the word early.”

With a nod of dark humor, she added, "It's a very dramatic way to get a boob job," vowing followers, "I will come back with massive boobs and more music." But under the humor lay raw emotion and an earnest appeal for sympathy and understanding. "I need to process it and talk about it," she said. "I need a hug."

Having struggled with a string of serious health problems in the past, including a childhood heart condition, a stroke at age 18, Meniere's disease, and even recently being diagnosed with ADHD and OCD, Jessie J is certainly no newcomer to working through health problems. But this latest installment has introduced her to an even more intimate, more personal view.

By disclosing her diagnosis, Jessie J is part of a rising number of public figures using their influence to make health screening and breast cancer discussions more mainstream. Such openness is particularly important in light of the fact that many young women still unrealistically believe breast cancer is an "older woman's disease."

Breast cancer is the most frequently diagnosed cancer in the world and the major cause of cancer death among women, reports the World Health Organization. But even with worldwide awareness efforts, delayed diagnosis remains a big issue. And that delay has part to do with failing to notice—or completely ignore—the warning signs.

What Are the Signs Women Typically Ignore?

While a breast lump is usually the most talked-about symptom, breast cancer has many other manifestations. These less common symptoms are important to recognize, particularly for women who might not think of themselves as high-risk.

1. Swelling in the arm or collarbone area

A subtle but significant indication is repeated swelling in the underarm or near the collarbone. This can suggest that cancer has spread to the lymph nodes—even when there is as yet no lump in the breast. Although the swelling could be minor or painless, any puffiness that is apparent and does not resolve should be investigated.

2. Recurring Breast or Chest Pain

Contrary to what many believe, breast cancer may be painful. Pain that isn't related to your menstrual cycle or physical exertion—particularly sharp, burning, or persistent dull pain—can't be ignored. Although not all breast pain indicates cancer, persistent pain warrants investigation.

3. Persistent Itchiness and Skin Changes

Persistent itchiness of the armpit or breast—especially if it is followed by redness, scaling, or swelling—may indicate inflammatory breast cancer, which is a rare but vicious type. Topical remedies that fail and localized itchiness warrant a visit to the doctor.

4. Persistent, Unexplained Fatigue

Fatigue is one of the most misdiagnosed symptoms. With the speed of life these days, it's simple to assume tiredness is caused by stress, parenting, or sleeplessness. However, persistent fatigue that is unrelieved by rest could be a sign your body is struggling with an underlying illness, such as cancer.

5. Inverted Nipple or Nipple Discharge

Any abrupt nipple changes, like turning inward or flattening, might mean that a tumor is putting pressure on the milk ducts. Similarly, spontaneous nipple discharge, particularly if bloody or unprovoked—must never be left unattended. Such symptoms might appear insignificant but can actually point to significant underlying problems.

Medical experts consistently stress the importance of becoming familiar with your own breast tissue and regularly performing self-exams. According to the UK’s NHS and the American Cancer Society, early detection is the most effective defense. That means not only attending routine mammograms after age 40 (or earlier if you’re high risk) but also being proactive about any bodily changes.

It's not just about finding a lump. It's about recognizing when something doesn't feel right—and trusting yourself enough to speak up.

Jessie J's choice to come forward wasn't for healing herself alone—it was to make others feel less isolated. "I also know how much sharing in the past has helped me," she explained. "People giving me their love and support and also their own stories."

Traditionally and otherwise too, what is usually used to treat open wounds, fish skin grafts have gained a lot of popularity in the research and medicine community. Research, like the study from 2023, published in the journal Cureus, showed that using fish skin graft helped wounds heal faster and reduce pain. Not only is it readily available, but it is also inexpensive to produce. The Nature, scientific reports explained that the highly porous nature of the fish skin is well suited to support cell ingrowth. While it has been used many times for different types of medical emergencies, the use of it on newborns had not been considered until this case.

Born premature at just 23 weeks and weighing only one pound, Eliana DeVos faced immense challenges from the beginning. Speaking to the CNN News, Eliana’s mom, Krystal DeVos, explained that Eliana had spent 131 days in neonatal intensive care, where she developed a severe, rapidly spreading infection on her neck. Her mom described it as "almost like a flesh-eating disease" that nearly claimed her life, leading to dangerous sepsis. As Eliana's condition deteriorated, her family and doctors desperately sought a solution.

An Unconventional Treatment

The treatment option the doctor chose, although unconventional, had a lot of hope. Doctors chose to use fish skin to heal her wound. The pediatric plastic surgeon, explained that Eliana was too fragile for traditional surgery or a human skin graft due to her prematurity and the extensive wound.

Instead, the doctor and the wound care nurse opted for a medical honey solution to clean the wound, followed by the application of medical-grade fish skin. This product, made from wild North Atlantic cod by the Icelandic company Kerecis, acts as a scaffold for new skin tissue to grow. Its structure is remarkably similar to human skin, and it's rich in omega oils and other natural healing elements. The remarkable thing about this fish skin graft

How Does A Fish Skin Graft Work?

Doctors believe Eliana was likely the first preemie of her size to receive this innovative treatment. While fish skin has been used globally for wound care, its application in children, particularly infants as tiny as Eliana, is uncommon.

Doctors highlighted that other animal tissues, known as xenografts, which are from animals like pigs or cows, are also used for wound healing. These don't replace skin but serve as temporary dressings to promote cleanliness and initiate healing. However, experts cautioned that not all wounds respond to these methods.

A significant concern with such treatments, especially in infants, is the potential for unknown allergies, particularly to fish. The biggest risk the doctors were worried about was the unknown allergy risk. If the baby had a fish allergy, it could’ve made things a lot more difficult. They also noted that even with these treatments, there's still a possibility that surgery might be necessary.

Recovery and Recuperation For the Infant

For Eliana's mom, the experience has been incredibly inspiring. She hopes people will recognize the immense value of modern medicine and the power of faith. She explained how immensely worried she was, however, it never stopped her from trying something new. She encourages people to try something new and be open-minded.