Image Credit: Health and me
A popular short cut to lose weight while managing diabetes has gained popularity since a couple of years with semaglutide-based drugs like Ozempic. In 2023 alone, nearly 2% of the U.S. population was prescribed semaglutide, reflecting its widespread acceptance as an effective treatment. However, as its usage grows, so does concern over its potential side effects, particularly those affecting vision. A new study published in JAMA Ophthalmology has sparked debate by suggesting a possible link between Ozempic and severe ophthalmic complications, including a rare condition known as nonarteritic anterior ischemic optic neuropathy (NAION), which can lead to sudden vision loss.
The JAMA Ophthalmology study analyzed nine patients who had been using semaglutide or tirzepatide, another similar drug. Of these patients- seven were diagnosed with NAION, a condition where reduced blood flow to the optic nerve leads to vision impairment. One patient developed papillitis, an inflammation of the optic nerve head. Another suffered from paracentral acute middle maculopathy (PAMM), a condition affecting the retina.
While the study does not establish a direct causal relationship between these drugs and vision loss, researchers speculate that the rapid blood sugar reduction caused by semaglutide could be a contributing factor. This sudden correction of hyperglycemia might lead to vascular changes in the eyes, compromising blood flow to critical visual structures.
The study raises concerns about three major eye conditions potentially linked to semaglutide-based drugs:
A condition characterized by sudden, painless vision loss due to blocked blood flow to the optic nerve. This is typically irreversible and has no effective treatment.
An inflammation of the optic nerve head that can cause swelling and vision disturbances.
A retinal condition resulting from restricted blood flow in deeper layers of the eye, leading to localized vision issues.
Semaglutide and tirzepatide belong to a class of drugs known as incretin mimetics, which function by increasing insulin secretion, reducing glucagon levels, and slowing gastric emptying. These mechanisms effectively lower blood sugar levels, making them valuable treatments for diabetes and obesity.
However, the body’s vascular system, including the delicate blood vessels in the eyes, is highly sensitive to fluctuations in blood sugar. A rapid drop in glucose levels may disrupt normal blood circulation in the optic nerve, leading to ischemic damage. This is a particularly concerning factor for individuals with preexisting conditions like diabetes, high blood pressure, or sleep apnea, all of which are known risk factors for NAION.
The findings have prompted responses from major medical organizations. In 2023, the American Academy of Ophthalmology advised patients experiencing vision loss while on semaglutide to discontinue the drug and seek immediate medical consultation. However, the academy stopped short of recommending against Ozempic or similar medications altogether.
Meanwhile, health officials in Denmark, where Novo Nordisk (the manufacturer of Ozempic) is based, have initiated their own investigation into potential links between semaglutide and vision loss.
Patients using Ozempic or similar medications should remain vigilant for symptoms that could indicate vision problems, such as:
If any of these symptoms arise, it is crucial to seek immediate medical attention to prevent further damage.
Beyond potential vision complications, Ozempic has been associated with a range of side effects, as outlined by the Mayo Clinic. These include:
Common side effects: Nausea, bloating, heartburn, diarrhea, and stomach discomfort.
More serious complications: Pancreatitis, stomach paralysis, biliary disease, and bowel obstruction.
While the current study does not conclusively establish a cause-and-effect relationship between Ozempic and vision loss, it highlights the need for further research. With millions of people using semaglutide-based medications, understanding the full scope of their effects is critical for ensuring patient safety.
Healthcare professionals emphasize that individuals should weigh the benefits and risks before starting or discontinuing any medication. Patients with preexisting eye conditions or vascular issues should consult with their doctors to determine whether Ozempic is the right choice for them.
Ozempic has revolutionized weight loss and diabetes management, but emerging research suggests that its effects on eye health require closer scrutiny. While the new findings do not definitively prove that semaglutide causes vision loss, they raise enough concern to warrant further investigation and cautious monitoring by both patients and healthcare providers. As studies continue, individuals using these medications should remain aware of potential risks and take proactive steps to protect their vision.
Credits: Getty Images and Canva
Shocking to many, expected for more, the US Health Secretary Robert F Kennedy Jr on Monday removed every member of a scientific committee that advises the Centers for Disease Control and Prevention (CDC) on how to use vaccines. He has also pledged to replace them with his own picks.
This is the Advisory Committee on Immunization Practices (ACIP), from where 17 members have been removed. This step has been criticized by many physicians and public health groups.
It may come as a shock to many, but in all fairness, it was known that Kennedy was among the nation's leading anti-vaccine activists before he became the nation's top health official. While he has revealed that the members will be his own pick, he has not said who would he appoint. However, as per reports, this should convene in two week in Atlanta. It is also important to note that the entire roster of committee members were in fact, Biden appointees.
In an opinion piece published in the Wall Street Journal, Kennedy wrote: “Without removing the current members, the current Trump administration would not have been able to appoint a majority of new members until 2028. A clean sweep s needed to re-establish public confidence in vaccine science."
The reports say that the former panel members received an email on a late Monday afternoon that said that their services had been terminated without any reason. Many of whom had not served a full term.
While his steps are being criticized, they must not be seen as a shock as Kennedy had already taken the unusual step of changing COVID-19 recommendations without first consulting the committee.
As per Kennedy, the committee members had too many conflict of interests. However, as the US News reports, Dr Tom Frieden, who is the president and CEO of Resolve to Save Lives and former director of CDC said that Kennedy's actions were based on false conflict of interest claims and that they set a "dangerous and unprecedented action that makes our families less safe". As this step can significantly reduce vaccine access to many people.
“Make no mistake: Politicizing the ACIP as Secretary Kennedy is doing will undermine public trust under the guise of improving it,” he said in a statement. “We’ll look back at this as a grave mistake that sacrificed decades of scientific rigor, undermined public trust, and opened the door for fringe theories rather than facts.”
ALSO READ: What Are The Key Takeaways From RFK Jr.'s CDC Press Conference On Autism Report?
In a podcast interview, he said, "There is no vaccine that is safe and effective" and told FOX News that he still believes in the now long-debunked idea that vaccines can cause autism. In another 2021 podcast, he urged people to "resist" CDC guidelines on getting their kids vaccinated. "I see somebody on a hiking trail carrying a little baby and I say to him, better not get them vaccinated," he said.
His non-profit also led an anti-vax campaign sticker and he appeared next on the screen to a sticker that read: "If you are not an anti-vaxxer you are not paying attention," reports AP. He told the FOX News that "autism comes from vaccine". However, vaccination has indeed saved more lives.
After taking the charge of the office, Dr Peter Marks, one of the top US Food and Drug Administration (FDA)'s leaders and scientist in vaccine regulation had also been ousted. Several sources have also reported that his resignation was not voluntary, in fact he was reportedly told to 'resign or get fired'.
Stay Updated On CDC and RFK Jr. Here
Credits: Canva
The Unites States reported 122 new cases of measles last week, which has brought the national total to 1,168 in 2025. This data is released by the Centers for Disease Control and Prevention (CDC). While the outbreaks in Pennsylvania and Michigan have officially ended, others across North America continue to unfold, including in parts of Texas, New Mexico, and Canada.
Measles is caused by a highly contagious airborne virus that spreads through coughing, sneezing, or even breathing near an infected person. It had been declared eliminated from the U.S. in 2000 thanks to widespread vaccination efforts. However, recent declines in vaccination rates and increased international travel have led to a resurgence. The disease can lead to severe complications such as pneumonia, encephalitis (brain swelling), and death, especially in unvaccinated individuals.
The best defense against measles remains the MMR (measles, mumps, rubella) vaccine, typically administered in two doses during early childhood. Yet, the U.S. has seen a growing number of vaccine exemptions, which health experts say undermine community immunity.
Texas experienced the country’s largest outbreak this year, with 742 cases reported across 35 counties. Most were concentrated in Gaines County, where a close-knit, undervaccinated Mennonite community accounted for more than half of the state’s total cases. Two unvaccinated children — aged six and eight — died in separate incidents earlier this year.
As of this week, fewer than 10 individuals in Texas are estimated to still be infectious. State health officials will now provide updates weekly instead of daily, suggesting the worst of the outbreak may be over.
As per CDC if a state reports three or more related cases, it would be defined as an outbreak:
Canada’s Ontario province has seen the longest outbreak in North America, with 2,009 cases and one death in a baby with congenital measles. Alberta has 761 cases. In Mexico, the state of Chihuahua reported 1,940 cases and four deaths.
Measles symptoms start with high fever, cough, runny nose, and red eyes, followed by a spreading rash. Complications can be severe, especially for young children and immunocompromised individuals. There is no specific antiviral treatment; care typically focuses on symptom management and avoiding further spread.
Credits: Canva
As the summer travel season peaks, the Centers for Disease Control and Prevention (CDC) has issued an important advisory to travelers about the re-emergence of measles in the US, specifically highlighting the risk of contracting the highly contagious disease at airports and other crowded transit points. Once being declared eradicated from the United States in 2000, measles has has made a unsettling comeback, fueled primarily by declining vaccination rates and global travel. With more than 1,100 reported cases across the country this year alone, the CDC's warning is a harsh reminder that this preventable illness is a very real and present danger—particularly in areas thick with travelers.
For generations, measles was a thing of the past in the U.S. due to widespread vaccination campaigns. The disease was almost eradicated over the last two decades, with only sporadic imported cases and small outbreaks occurring. Recent trends, though, have turned this tide of progress around. This year's figure of 1,157 cases already exceeds numbers from earlier years, indicating a public health problem not witnessed since 2019, when a large-scale outbreak rocked communities.
Much of this increase stems from a multistate outbreak concentrated in West Texas, but the risk is far from localized. The CDC highlights that the virus is highly contagious and can spread rapidly in places like airports, train stations, planes, crowded events, and tourist attractions—anywhere large numbers of people converge, particularly if some are unvaccinated or susceptible.
Airports stand out for their ability to transmit disease. They are gateways to and from around the world with tightly packed crowds, frequently crowded waiting rooms, and intimate mingling among travelers from all parts of the globe—some from nations where measles remains endemic. The CDC travel notice emphasizes that travelers can catch measles while in these locations, then return home with the virus and spread it further.
The extreme infectiousness of measles makes it so that casual exposure to an infected individual or contact with contaminated surfaces can result in infection. Fever, cough, rash, and serious complications such as seizures and blindness are all symptoms that make it a dangerous virus, particularly for infants, pregnant women, and the immunocompromised.
The resurgence is largely due to vaccine hesitancy and disinformation that have caused some parents to skip or postpone childhood vaccinations. The implications are evident: areas of under-immunized communities are fertile breeding grounds for measles outbreaks. Anti-vaccine attitudes, in some cases spurred on by misinformation and suspicion of medical institutions, have been a prime force behind the current resurgence.
Adding to this problem is the amount of travel anticipated this summer. As millions of American travelers flood airports, trains, and vacation spots, the risk of transmission increases, particularly in areas with lower vaccination levels.
The CDC advises all international travelers to make sure they are up to date with their measles vaccination, including two doses of the measles-mumps-rubella (MMR) vaccine at least 28 days apart. Infants 6 to 11 months old traveling internationally should also receive an additional dose of MMR vaccine prior to travel.
Those born prior to 1957 are presumed to have had natural immunity from childhood exposure and thus are not recommended to be vaccinated by the CDC or Texas public health officials except in the case of healthcare personnel who work in outbreak areas, for whom two doses should be administered regardless of year of birth.
Some individuals, like pregnant women, infants younger than six months, and individuals with severely compromised immune systems, are not eligible for the vaccine. These persons should speak with their physicians regarding their individual risk and possible preventive action, like immunoglobulin therapy, that will provide temporary protection once exposed.
Experts recommend that travelers take a proactive role by getting their immunity status checked sufficiently in advance of their travel—ideally six weeks or more ahead. This can include checking vaccination history, laboratory tests, or evidence of previous infection. Suspected exposure to measles calls for immediate medical consultation, since early administration of MMR vaccine or immunoglobulin can cut down on disease severity.
Along with vaccination, routine preventive precautions are important: frequent washing of hands, avoidance of contact with the sick, remaining in well-ventilated places, and use of masks when required, particularly for those with high risks of developing complications.
Travelers need to prepare as well by bringing along medications that are necessary and learning about healthcare facilities in the destinations. Checking the CDC's travel health notices may offer current information on risks and vaccine requirements for countries.
The recent measles outbreak is a cautionary example of the vulnerability of disease elimination efforts. Even as vaccination campaigns have long kept measles at bay, recent slippages risk undoing decades of gains. The warnings from the CDC occur at a time when wider concerns exist regarding vaccine misinformation and waning public trust in immunizations.
The consequences are dire. Measles is not a harmless childhood disease; it can result in severe complications, hospitalization, and even death. Already this year, at least two children and one adult have died from measles-related complications in the United States, and these figures may increase as travel continues and outbreaks multiply.
Travelers need to understand that immunity is the best defense against measles. Howsoever healthy your living style, germs do not distinguish between people—germs infect the unimmunized, the weak, and those who come in close proximity to carriers equally.
© 2024 Bennett, Coleman & Company Limited