Five years since COVID-19 brought the world into a health and economic crisis, the World Health Organization (WHO) has done what many considered unlikely—a global agreement on a draft pandemic treaty. On Wednesday, after years of intricate talks and political upheaval, WHO member states reached a consensus on a historic document that will determine how the world responds to future pandemics. If endorsed at the next World Health Assembly in Geneva, the treaty would have the potential to be a turning point for global public health partnership and readiness.
WHO Director-General Dr. Tedros Adhanom Ghebreyesus greeted the treaty as a badge of unity. "In our polarized world, countries can once again agree and unite for a common response," he said. The pact should bring revolutionary change to how nations prepare and react to health emergencies globally—without repeating the inequities, delays, and fragmented responses that characterized the response to COVID-19.
The global response to COVID-19 revealed systemic weaknesses in international health governance—ranging from vaccine hoarding and disinformation to less-than-generous support for poor countries. These shortcomings prompted WHO member states to create the Intergovernmental Negotiating Body (INB) in December 2021. Their task: to negotiate a strong international instrument centered on prevention, preparedness, and fair response to future pandemics.
Following these were 13 formal sessions, longer-than-usual sessions, and numerous informal discussions. Geopolitical splits and continuous withdrawals from the WHO by such leaders as past U.S. President Donald Trump and Argentina President Javier Milei could not stop the INB finalizing a draft agreement ahead of the official adoption in May 2025.
The suggested agreement has the purpose of establishing a global pandemic response playbook, based on solidarity, equity, and science. Among its most important elements:
Pathogen Access and Benefit Sharing: The treaty requires that nations providing virus samples will enjoy assured access to derived diagnostics, medicines, and vaccines. For its enforcement, WHO will hold up to 20% of such products to guarantee equitable distribution, particularly to low-income countries.
One Health Approach: Acknowledging the interconnectivity of human, animal, and environmental well-being, the treaty promotes cooperation to avoid zoonotic outbreaks and emerging dangers.
Technology Transfer and Capacity Building: The pact ensures transfer of scientific information, manufacturing technology, and capability across countries to develop a geographically dispersed R&D base. This should eliminate geographical concentration of global health innovation and end reliance upon a handful of dominant nations.
Emergency Health Workforce and Supply Chains: States are urged to establish competent health emergency workforce teams and be part of a global supply chain and logistics network for swift response to future health emergencies.
Respect for Sovereignty: Notably, the draft treaty confirms that the WHO will not impose national health legislation or mandates like lockdowns, vaccination orders, or travel restrictions. National sovereignty is preserved, although cooperation is strongly urged.
Though the treaty is a milestone, it is not without controversy. The United States, having been sidelined in Trump's administration pullout from the WHO, is still far from the finalization of the treaty. Though U.S.-based R&D was key to creating effective COVID-19 vaccines and treatments, American officials are not likely to sign the agreement under present provisions.
Likewise, Argentina's recent withdrawal from the WHO is a sign of ongoing distrust among some leaders regarding the role and authority of international health organizations. Opponents claim that international treaties threaten national interests or overreach their limits in governing public health.
The pandemic treaty in draft form is an increasing recognition that no state, no matter how rich or resourceful, can tackle a global pandemic in isolation. It emphasizes the call for transparency, equity, and multilateralism during times of crisis. Adopted at the World Health Assembly in May, the treaty might transform the way the world prepares for and prepares against pandemics—making sure that scientific advancements and essential resources are available to everyone.
As the globe looks back at the tragic losses and bitter lessons of COVID-19, this treaty presents an opportunity to redefine global health in partnership, not rivalry. To future generations, it may signal the start of a more cohesive and resilient global response to common dangers.
Credit: Instagram/Oprah Winfrey
American host Oprah Winfrey, who told her fans she was taking GLP-1 weight loss medication in 2023, has revealed that she stopped taking injections for a short period of time last year and ended up gaining significant weight.
During an episode of the TODAY show with Jenna & Sheinelle, Winfrey, 71, said: "I was off the (weight loss medications) all last year and I gained 20lbs because I wanted to test it.
"Because everyone was saying 'you're going to gain the weight' (and) I'm going to show them that I'm not going to gain the weight. I'm going to hike."
However, the media mogul ended up gaining most of her weight back, citing that once she was off the medications, she would stand in front of the refrigerator thinking "what can I eat".
Researchers have found that those who lose weight using blockbuster GLP-1 drugs such as Ozempic could regain about 0.4kg every month after quitting these treatments. In contrast, those who lost weight through exercise, diet and other factors only gained 0.1kg.
Ozempic (semaglutide) is a prescription injectable GLP-1 medication primarily approved for adults with Type 2 diabetes to manage blood sugar levels. However, the drug has gained immense popularity among those trying to lose weight as it can reduce hunger and help people feel full for longer, which forces the body to burn fat deposits to stay functional.
In clinical trials, people with obesity using semaglutide have shown to lose an average of about 15% of their body weight over 68 weeks. Most people begin to see noticeable results within 8 to 12 weeks of taking the drug.
The official price in India for a once-weekly Ozempic injection pen ranges from approximately ₹8,800 for the 0.25 mg dose to around ₹11,175 for the 1 mg dose per month. Insurance coverage is generally inconsistent for weight loss indications.
In an exclusive interview with PEOPLE, the OWN founder noted that in the last two years, her relationship with food and exercise has changed drastically, in addition to erasing her taste for alcohol.
'The fact that I no longer even have a desire for it is pretty amazing,' Winfrey said.
The talk show legend once admitted she was able to :outdrink everyone at the table" and "was a big fan of tequila". "I literally had 17 shots one night," she said, "I haven't had a drink in years. The fact that I no longer even have a desire for it is pretty amazing."
Additionally, Winfrey said she no longer obsesses over food and has embraced exercise for the first time in her life. However, once she understood that she began to gain weight when she stopped taking injections, Winfrey realized that the medication will likely be "a lifetime thing".
"It's going to be a lifetime thing. I'm on high blood pressure medication, and if I go off the high blood pressure medication, my blood pressure is going to go up. The same thing is true now, I realize, with these medications. I’ve proven to myself I need it," she told the publication.
Winfrey now typically takes the shots weekly, but sometimes stretches them to 10 or 12 days. "You need to start slow and gradual,' she advised. 'If you start by taking too much at one time, you have more of a chance of messing yourself up
Apart form this, the media star also now works out for about two hours a day, six days a week, hiking, doing cardio or strength training.
Credit: Canva
A new British study has discovered that social media use or video gaming is not causing mental health problems in young teenagers.
For decades, experts across industries have warned that time spent on social media platforms such as TikTok, Instagram or gaming platforms could be driving a rise in anxiety and depression among teenagers.
However, researchers from the University of Manchester claim to have found little to no evidence over links of such claims.
Lead author Dr Qiqi Cheng said: "We know families are worried, but our results do not support the idea that simply spending time on social media or gaming leads to mental health problems, the story is far more complex than that."
The researchers tracked pupils’ self-reported social media habits, gaming frequency and emotional difficulties over three school years to find out whether technology use genuinely predicted later mental health difficulties.
The researchers found no proof that heavy social media use or more frequent gaming caused increases in symptoms of anxiety or depression over the following year - for both boys or girls.
Girls who gamed more often went on to spend slightly less time on social media the following yea and boys who reported more emotional difficulties were more likely to cut back on gaming in the future. This suggested links between losing interest in hobbies when feeling low or parents limiting screen time when they notice their child is struggling.
The research team also explored whether actively chatting on social media or just passively scrolling made a difference but results stayed the same
The authors emphasize that this does not mean online experiences are harmless. Hurtful messages, online pressures and extreme content can still impact wellbeing but they argue that focusing simply blaming screen time is not enough and more attention needs to be paid.
Constant comparison on social media, cyberbullying and pressure to fit in online or offline significantly impact self-esteem and increase anxiety. Apart from this, exposure to violence, neglect, abuse or poverty during these formative years is a major risk factor for developing mental illnesses like PTSD, depression and anxiety.
Additionally, some adolescents are also genetically more susceptible to mental health conditions, which can be triggered by environmental stressors.
Credits: Canva
Flu has now reached California, officials at the California Department of Public Health (CDPH) confirmed on Tuesday. The mutated influenza strain, which is dubbed as the 'super flu' is now spreading in California.
The CDPH confirmed a second pediatric death related to flu since the season of this respiratory virus had started. The 'super flu' strain is the mutation of seasonal influenza A H3N2 virus, called the subclade K. While the cases are on the rise, with some record breaking ER visits and hospitalizations, the Centers for Disease Control and Prevention (CDC) noted that the season has not peaked yet, and that there might be more cases in the coming week.
Dr Monica Gandhi, who is an infectious disease expert at UC San Francisco told SFGATE that people infected with the mutated strain will likely get common flu symptoms, such as body aches, fever, cough and headache. "I think this particular strain makes people feel pretty horrible," Gandhi said, and further added, "And the reason that subclade K is important is it may not be covered by the current flu vaccine."
However, experts are still asking people to get vaccinated. In fact, the CDC has also noted that vaccination "has been shown to reduce the risk of flu and its potentially serious complications". However, only 130 million doses of vaccine have been distributed, which covers less than 40% of the US population. "The vaccine remains the most effective means to prevent disease. We still want to encourage people to get the vaccine," said Professor Antonia Ho, Professor and Honorary Consultant in Infectious Diseases at the University of Glasgow. Experts have stressed enough on the immunity that one can receive from the vaccine that that these flu jab remain the best defense against the flu, even though the current strain circulated may have drifted away from the strain included in this year's jab.
Data from the UK Health Security Agency (UKHSA) also show that vaccines is performing as expect, despite the emergence of subclade K.
K variant causes more intense flu symptoms, they include:
This year's flu came after the flu vaccination was made, which means the current vaccination does not align with the mutation, however, experts have pointed out that it still continues to offer protection against the illness.
Flu activity in the state has shown a downtick from the season high at the end of the December. 15% of flu tests have come back positive by January 3, which is down from 17% rate seen during the week ending with December 27. However, the CDC noted that this downtick does not mean the end of flu season, it could rather mean that less cases were reported due to the holiday season. As the agency has warned more such cases to show up in the coming week.
In fact, hospitalization have been on the rise and hit a season high with 3.8 admissions per 100,000 in the state as of January 3.
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