Women With Autoimmune Diseases Face Greater Risk Of Deadly Heart Complications; How To Protect Yourself?

Updated May 10, 2025 | 05:00 AM IST

Women With Autoimmune Diseases Face Greater Risk Of Deadly Heart Complications; How To Protect Yourself?

SummaryAutoimmune diseases occur when the immune system mistakenly attacks the body’s own tissues, leading to chronic inflammation, pain, organ damage, and increased risk of cardiovascular complications, especially in women.

Autoimmune illnesses like rheumatoid arthritis (RA), lupus, and systemic sclerosis have long been famous for their creation of chronic inflammation and joint devastation, but new evidence is surfacing that these diseases are subtly damaging the heart—particularly among women. The study, reported in Circulation: Cardiovascular Quality and Outcomes, estimated that women who have these disorders are at 50% higher risk of heart disease-related death than men. Although progress has been made in treating autoimmune diseases, the cardiovascular dangers they pose—especially to women—are underdiagnosed and undertreated.

Autoimmune illnesses are much more common in women. Almost twice to three times as many women have RA compared to men, and with lupus, it is nine times as many. Systemic sclerosis, characterized by tightening of the skin and possible damage to internal organs, also occurs more often in women.

The higher cardiovascular death rate in women with these diseases is not just a statistical coincidence. Dr. Heba Wassif, Director of Cardio-Rheumatology at Cleveland Clinic and senior author of the study, highlights that the burden of cardiovascular disease in immune-mediated inflammatory conditions is both substantial and disproportionately impacts women. This prompts important questions about how autoimmune-driven inflammation specifically affects women's cardiovascular health—and why their risks have been so historically underestimated.

In perhaps the most thorough analysis yet, scientists sifted through data on over 281,000 deaths attributed to RA, lupus, and systemic sclerosis between 1999 and 2020. More than 127,000 of those were from heart complications.

While overall mortality rates for heart disease fell—from 3.9 to 2.1 per 100,000 among women and from 1.7 to 1.2 among men—the gap between men and women narrowed only slightly: women continued to die from heart disease at disproportionately higher rates.

Even more alarming, stroke and blocked arteries (atherosclerosis) became the leading killers of women, along with the stark rate of deaths due to irregular heart rhythms and cardiac arrest—over twice that of men.

How Autoimmune Inflammation Damages the Heart?

Autoimmune diseases induce the body to mistakenly attack its own tissues. In RA, the immune system assaults the synovium—the joint lining—leading to swelling, pain, and inflammation. But this inflammation does not end here. It can spread to essential organs, such as the heart, lungs, and blood vessels.

Chronic inflammation promotes the formation of plaque in arteries, damages the linings of blood vessels, and accelerates atherosclerosis—a key risk factor for heart attack and stroke. In addition, the systemic inflammation can provoke arrhythmias and worsen heart failure.

The same medications that treat autoimmune diseases—like corticosteroids and certain immunosuppressants—can also increase cardiovascular risks indirectly by elevating blood pressure, blood sugar, or cholesterol levels if not monitored carefully.

How Heart Diseases have Become a Leading Killer in Autoimmune Patients?

Dr. Issam Motairek, lead author of the study, points to a dramatic change in the perception of mortality among autoimmune patients. "There is a general belief that individuals with immune-mediated inflammatory diseases die mostly from infections or kidney disease," he said. "But our study found that one-third of deaths in this group were caused by cardiovascular disease."

This change points to an urgent necessity to rephrase the way we perceive autoimmune conditions—not only as musculoskeletal or cutaneous problems, but as inflammatory disorders of the whole body with lethal cardiovascular ramifications.

Ways to Control Autoimmune Flares to Keep Your Heart Safe

Most of this cardiovascular danger can be avoided. Here is the way in which women suffering from autoimmune disorders can actively shield their heart:

Early and recurrent cardiovascular screening – At the diagnosis of autoimmune disease, screening should be done by Dr. Wassif and then on a regular basis thereafter. This will include blood pressure, cholesterol, glucose levels, and inflammation markers.

Aggressive inflammation control – Treatment of RA or lupus early and effectively not only benefits the joints but also curtails systemic inflammation that can harm the heart.

Lifestyle interventions – Exercise, a heart-healthy diet, stress reduction, and smoking cessation are even more crucial in this group. Exercise may be difficult during flare-ups, but low-impact exercise such as walking or yoga can be helpful.

Weight control – Achy joints and fatigue can reduce mobility, promoting weight gain. But obesity itself is a principal cause of high blood pressure, diabetes, and heart disease—each of which multiplies the risks for autoimmune patients.

Collaborative working with healthcare providers – Rheumatologists, cardiologists, and primary care physicians must work in concert. An expert cardio-rheumatology team, such as at premier institutions like Cleveland Clinic, can provide individualized care.

Of all autoimmune conditions researched, rheumatoid arthritis carried the greatest risk of cardiovascular mortality. RA not only inflames joints—it can also cause damage to heart valves, inflammation of the heart muscle (myocarditis), and pericarditis (inflammation of the outer layer of the heart). In addition, RA is frequently accompanied by fatigue, low-grade fever, and decreased activity—all of which can conceal or exacerbate heart disease.

This seminal study should be an eye-opener for both patients and clinicians. It reinforces the need not to brush off symptoms such as palpitations, chest pain, shortness of breath, or fatigue in women with autoimmune diseases. It also highlights the imperative of greater gender-specific research and an overarching, preventive approach to autoimmune diseases—not merely for joint well-being, but for survival.

If you’re a woman living with an autoimmune inflammatory disease, protecting your heart isn't optional—it’s essential. Don’t wait for a cardiac symptom to speak up. Be your own advocate, and demand comprehensive cardiovascular care. Early detection, effective inflammation control, and lifestyle support can go a long way in reducing your risk—and adding years to your life.

End of Article
Former Australian PM Barnaby Joyce Diagnosed With Prostate Cancer, To Undergo Surgery

Credit: Canva

Updated May 10, 2025 | 08:35 AM IST

Former Australian PM Barnaby Joyce Diagnosed With Prostate Cancer, To Undergo Surgery

SummaryProstate cancer is a type of cancer that occurs when malignant cells form in the prostate gland, which is a walnut-sized gland in the male reproductive system.

Former Deputy PM of Australia and Nationals MP Barnaby Joyce said that he has been diagnosed with prostate cancer. Joyce, who was recently re-elected to his New England seat, said he will undergo surgery on Monday. Nearly 25,000 men, on average, are diagnosed with prostate cancer every year, according to statistics by the Australian government.

Speaking to ABC News, the 58-year-old said that he had not experienced any symptoms, but his doctor recommended a prostate-specific antigen (PSA) blood test. The test results indicated elevated PSA levels, leading to an MRI and biopsy that confirmed the cancer diagnosis. Prostate cancer is the most prevalent cancer among men, affecting one in eight men over their lifetime. Joyce expressed gratitude for the early detection and said he is optimistic about making a full recovery.

"If you catch prostate cancer early, it is highly treatable – with a success rate of about 97%," Joyce stated, urging men to be vigilant about symptoms and consider taking the PSA test for early detection. Following the surgery, Joyce plans to take some time off to recover. "I'll be resting as instructed by my family," he said, noting that his wife has prohibited him from engaging in farm work during his recovery period.

How To Identify Prostate Cancer?

Prostate cancer is a type of cancer that occurs when malignant cells form in the prostate gland, which is a walnut-sized gland in the male reproductive system. Prostate cancer treatment guidelines have shifted their path a bit in recent years, with many men opting for active surveillance rather than immediate treatment for slow-growing tumours. However, about 50% of men on "watchful waiting" will require further treatment within 5 years because of the tumour progression. This is what triggered many researchers to aim and identify whether dietary modifications, specifically increasing omega-3 fatty acids, could prolong this surveillance period and slow down the tumour progression.

Prostate cancer that's more advanced may cause signs and symptoms such as:

  • Trouble urinating
  • Decreased force in the stream of urine
  • Blood in the urine
  • Blood in the semen
  • Bone pain
  • Losing weight without trying
  • Erectile dysfunction
Prostate cancer treatment and management vary based on the stage and severity of the disease. Early-stage cancer may be monitored through active surveillance, involving regular check-ups without immediate intervention. More advanced cases may require surgery to remove the prostate gland, radiation therapy to target cancer cells, or hormone therapy to reduce testosterone levels that fuel cancer growth. Chemotherapy and targeted drug therapies may also be employed in metastatic cases. Lifestyle modifications, such as a healthy diet, regular exercise, and stress management, can support overall health during treatment. Early detection and timely intervention significantly improve treatment outcomes.

ALSO READ: Prostate Removal Could Be The Solution To Erectile Dysfunction

End of Article
Measles Outbreak 2025: Cases in US Surpass 1,000, CDC To Reassess Treatments

Credit: Canva

Updated May 10, 2025 | 07:28 AM IST

Measles Outbreak 2025: Cases in US Surpass 1,000, CDC To Reassess Treatments

SummaryAs of Wednesday, at least 1,002 measles cases have been confirmed this year, based on figures from the US Centers for Disease Control and Prevention (CDC) and state health departments.

United States (US) is witnessing a concerning surge in measles cases, with more than 1,000 reported so far since the beginning of 2025. This is only the second time since the disease was declared eliminated in America 25 years ago that the number of cases has risen this high. A widespread outbreak spanning multiple states continues to escalate, placing the country on course for what could become the worst year for measles since 2000.

As of Wednesday, at least 1,002 measles cases have been confirmed this year, based on figures from the US Centers for Disease Control and Prevention (CDC) and state health departments. The majority of these cases (over 800) are linked to a significant outbreak concentrated in West Texas that has spread to New Mexico, Oklahoma, and potentially Kansas. Additional cases from some of these states are expected to be reported on Friday.

Health experts caution that the actual number of measles cases is likely undercounted, as many cases go unreported. The current outbreak underscores a troubling rise in cases, similar to the spike in 2019 when New York City and surrounding areas reported a major surge, contributing to a total of 1,274 confirmed cases that year. By comparison, the first five months of 2025 have already seen 1,002 cases – only 272 fewer than the entire year of 2019.

While the CDC continues to update national data on measles cases every Friday, it has ceased providing specific state-by-state case counts. As of Friday, the CDC reported 935 cases nationwide, with approximately 13% resulting in hospitalization. Only about 4% of the affected individuals had received at least one dose of the measles-mumps-rubella (MMR) vaccine. The outbreak has also led to three measles-related deaths this year – equaling the total number of such deaths over the previous two decades.

According to the CDC, a measles outbreak is defined as three or more related cases. So far in 2025, at least 12 such outbreaks have been identified. Besides the large cluster in West Texas, other states experiencing outbreaks include Ohio, with over 30 reported cases, as well as Montana and Michigan.

The rising numbers have prompted Health and Human Services Secretary Robert F. Kennedy Jr. to call for the CDC to reassess treatments for measles and other infectious diseases. As the outbreak continues to grow, public health officials urge Americans to stay vigilant and ensure they are up to date with MMR vaccinations

End of Article
FDA Approves First At-Home Cervical Cancer Screening Test Kit That Could Replace Pap Smears

Credits: Canva

Updated May 10, 2025 | 01:00 AM IST

FDA Approves First At-Home Cervical Cancer Screening Test Kit That Could Replace Pap Smears

SummaryThe FDA-approved is the first at-home cervical cancer screening test that detects HPV using a self-collected vaginal swab, offering a less invasive alternative to traditional Pap smears.

The U.S. Food and Drug Administration (FDA) has recently cleared and approved the at-home test for cervical cancer, possibly revolutionizing the way millions of women handle one of the most important parts of preventive health care. Created by Teal Health, the recently approved self-test device—the Teal Wand—provides an alternative, less painful method than the conventional Pap smear, seeking to make it easier, less stressful, and more accessible for cervical cancer screening.

The product, called the Teal Wand, allows women to collect vaginal swabs themselves at home—providing a potent, less painful alternative to conventional in-clinic Pap smears.

This approval represents a groundbreaking step toward breaking down long-standing barriers to screening for cervical cancer, particularly among women who find pelvic exams unpleasant, inaccessible, or culturally daunting. For them, it could be the bridge they've waited years for to early detection and timely treatment.

Cervical cancer ranks among the most preventable types of cancer owing to the existence of HPV vaccination and routine screening. However, despite increased medical capabilities, screening rates have consistently decreased since the mid-2000s. According to a 2022 study, 23% of women in 2019 were overdue for a cervical cancer screening, which was up from 14% in 2005. Almost half of all women diagnosed with cervical cancer in the United States, according to the American Cancer Society, are not current on their screenings.

This alarming trend is part of the estimated 13,360 new cases of cervical cancer and 4,320 deaths projected for 2025. The intent is for this home test to turn that trend around by reaching women where they're at—literally.

How the Test Kit Work?

The Teal Wand detects human papillomavirus (HPV), the primary cause of cervical cancer, using a self-collected vaginal swab that detects high-risk strains of the virus—just as a clinician would get a sample with a Pap smear, without the office visit and speculum.

To have access to the test, patients first have to meet with a Teal Health-affiliated provider through telehealth. If they are approved, the test is mailed to their home. After the sample has been taken, it is sent to a laboratory for processing. In case the test comes back positive for high-risk HPV, Teal Health's providers coordinate follow-up diagnostic care through in-office procedures as usual.

The advantages of this home test go beyond convenience—it could shrink the equity chasm in access to health care. According to a recent JAMA Network Open report, rural women are 25% more likely to have cervical cancer and 42% more likely to die from cervical cancer than city women. Disparities frequently are explained as a result of infrequent screening and inadequate availability of gynecologic services.

By facilitating home self-screening, the Teal Wand could assist underserved and rural communities in obtaining vital early diagnoses, possibly saving thousands of lives.

Role of HPV in Cervical Cancer

HPV is a sexually transmitted disease that most commonly resolves spontaneously. But some strains are associated with cervical and other cancers. The HPV vaccine, when given prior to sexual activity, is extremely effective in preventing illness from the high-risk strains.

As of a 2025 American Cancer Society report, incidence of cervical cancer in women between the ages of 20 and 24 decreased by 65% from 2012 to 2019 due primarily to early HPV vaccination. However, not all women are sharing in this success. Rates of cervical cancer in women in their 30s and early 40s have started to creep upward once more.

The Centers for Disease Control and Prevention (CDC) prescribes two doses of the HPV vaccine between preteens aged 11–12, although it can begin as early as age 9. Individuals having the first dose at 15 years and older need a series of three doses. The vaccine is usually prescribed up to age 26 and up to age 45 in special situations depending on personal risk.

Worldwide, cervical cancer continues to be the fourth most frequent female cancer and is responsible for 7.5% of all female cancer deaths, based on the World Health Organization (WHO). In the United States alone, there are about 200,000 women diagnosed with cervical precancer each year and over 11,000 with HPV-related cervical cancer. Unfortunately, more than 4,000 American women die from the disease each year.

Data from an 11-year study in England also supports the efficacy of early HPV vaccination and screening. The program there averted 448 cases of cervical cancer and more than 17,000 cases of precancerous lesions, highlighting the huge promise of proactive, accessible prevention strategies.

Although the Teal Wand now must be prescribed through Teal Health's telehealth platform, the business is continuing to move toward availability through additional healthcare providers. Pricing and insurance coverage are also points of interest. Because cervical cancer screening is supported by the U.S. Preventive Services Task Force, coverage is also highly anticipated, which would further drive accessibility.

End of Article