Scientists from the UK and the US have developed the world’s first online calculator that predicts whether a rare blood cancer—Hodgkin lymphoma—is likely to return within two years of treatment. And it involves just science, numbers, and 20 years of painstaking research.

The tool, known as E-HIPI (Early-stage Hodgkin Lymphoma International Prognostication Index), is a serious game-changer. Built using data from more than 5,000 patients involved in international clinical trials, it is the first risk model of its kind designed specifically for early-stage classic Hodgkin lymphoma (cHL)—a cancer that messes with your lymphatic system by attacking your white blood cells.

What it does and how it works

E-HIPI draws on real clinical data, everything from a patient’s sex and tumour size to their haemoglobin and albumin levels. In less than a minute, it can give clinicians a pretty reliable sense of how likely a patient is to relapse within two years of completing treatment.

Why this matters

Hodgkin lymphoma is one of the more treatable cancers, especially when caught early. But for a significant number of patients, the disease comes back and often with a vengeance. When a relapse happens, it usually means the patient has to go through more aggressive treatments like high-dose chemotherapy or even a stem cell transplant, which come with higher risks, longer recovery times, and a bigger emotional toll.

So having a tool like E-HIPI that gives doctors and patients a heads-up about the risk of relapse is more than just helpful; it could literally be lifesaving.

The serious side of a relapse

A relapse of Hodgkin lymphoma can be brutal. It means starting all over again, often with more intensive and targeted treatment. In some cases, patients who have relapsed also have a harder time responding to therapy, and their prognosis may not be as favourable the second time around.

That is why identifying high-risk patients early is so crucial. With E-HIPI, doctors can now tailor treatment more precisely, opting for more aggressive care for those who need it and sparing others from unnecessary side effects.

From Manchester to New Jersey: a global effort

E-HIPI is the product of a remarkable international collaboration. Scientists and clinicians from the University of Manchester and The Christie NHS Foundation Trust joined forces with top institutions in the US like RWJBarnabas Health, Rutgers Cancer Institute, and Tufts Medical Center.

Co-author of the study and Professor John Radford, Professor of Medical Oncology at The University of Manchester and Consultant Medical Oncologist at The Christie NHS Foundation Trust, told the Express UK: "This is the culmination of two decades of work. We wanted to find a better way to predict the outcome of people with early-stage Hodgkin lymphoma following treatment."

He added: "Until now we have lacked a robust tool, but we can now forecast how well individual patients are likely to respond to treatment, offering hope for more tailored and effective therapies. Crucially, the new tool can estimate a patient's likelihood of remaining cancer-free two years after treatment, which is a real game-changer. For some patients, it may mean avoiding overtreatment and its long-term side effects. For others, it may flag the need for closer monitoring or more intensive therapy."

Just as British summer hits full swing, the UK’s Food Standards Agency (FSA) has dropped a warning: slushies may not be so child-friendly after all. In an urgent new advisory, the FSA has warned parents to steer clear of giving slush ice drinks to children under seven, especially those containing a chemical called glycerol. And for kids between seven and ten? Keep it to a strict 350 ml a day.

What’s So Dangerous About a Slushie?

Slushies may seem like they beat the heat, but beneath that colour lies a syrupy science experiment. Most commercial slush drinks get their signature texture from glycerol, a compound that keeps ice from freezing into one giant block and gives slushies their semi-liquid, chewable charm. The trouble is, glycerol is harmful when consumed in large quantities, especially by small bodies.

According to the FSA, excessive intake of glycerol in a short span can cause mild symptoms like nausea, headaches and vomiting. But in more severe cases, children can suffer from dangerously low blood sugar, go into shock, or even lose consciousness.

The Risks Are Real and Rising

This warning did not come out of nowhere. The FSA has seen a surge in reports of children collapsing after drinking slushies. In many of these cases, the affected kids had consumed slush drinks in large amounts over a short period.

Summer’s New Parenting Rule

The FSA is urging parents and carers to be vigilant. Before buying a slushie, they recommend asking vendors whether the drink contains glycerol. If you are not sure, play it safe, especially with younger kids. Parents should also keep an eye on home-use slush kits and ready-to-drink slush pouches, which may also include this ingredient.

The shops have now also been instructed to stop offering free slushie refills for children under 10 and to use the minimal amount of glycerol necessary to get that slushy texture.

What to Do If a Slushie Turns Sour

If your child starts feeling queasy or dizzy after downing a slushie, do not panic, but do act. In mild cases, giving them a sugary snack or drink can help stabilise blood sugar levels. But if your child seems lethargic, confused, or unresponsive, call 999 immediately. It is better to be overly cautious than to risk a serious health episode.

Slushie Season, But Make It Safer

This new advice arrives just ahead of the school summer holidays, the peak slushie season in the UK. As temperatures soar, these icy drinks will be everywhere. The message from the FSA is clear: slushies are not forbidden, but they are not harmless either. Especially when they are packed with glycerol and served up to tiny tummies.

Legendary pop singer Connie Francis, whose voice defined an era with heartbreak ballads and upbeat rock-n-roll hits, has died at the age of 87. Her publicist and longtime friend, Ron Roberts, confirmed the news on Facebook on Thursday, writing:

“It is with a heavy heart and extreme sadness that I inform you of the passing of my dear friend Connie Francis last night. I know that Connie would approve that her fans are among the first to learn of this sad news.”

Though the cause of her death has not yet been made public, Francis had been hospitalized just two weeks earlier for what she described as “extreme pain” due to a pelvic fracture. The beloved singer had kept fans updated about her health condition through heartfelt posts on social media.

Health Struggles in Her Final Days

On July 2, Francis shared that she had been hospitalized in Florida, undergoing tests to identify the cause of her pain. Her updates were filled with optimism, despite having been moved to the intensive care unit and missing a scheduled appearance on Cousin Brucie’s Independence Day radio show.

By July 3 and 4, Francis posted that she was “feeling much better,” and expressed gratitude for her supporters. However, she remained under medical observation, and in a post the following week, she revealed that doctors were still trying to get to the root of her condition.

This wasn’t her first health battle.

In May, Francis had shared that she had suffered a hip injury that left her temporarily wheelchair-bound. Her openness about her condition made her all the more endearing to longtime fans who had followed her through the highs and lows of both her professional and personal life.

A Trailblazing Career That Crossed Borders and Genres

Born Concetta Rosa Maria Franconero in 1937, Connie Francis rose to fame in the late 1950s with her breakthrough hit “Who’s Sorry Now,” a song that she famously performed on television after nearly being dropped by her label. The track became a massive hit, charting internationally and setting the stage for a string of chart-topping singles.

She followed with hits like “Stupid Cupid,” “Lipstick on Your Collar,” “Don’t Break the Heart That Loves You,” and the carefree anthem “Vacation.” Her clear, emotional voice resonated with millions and helped her bridge musical genres—from rock ’n’ roll and country to standards and international ballads.

Francis sang in more than a dozen languages, including Italian, Yiddish, and Swedish, and found global success at a time when international stardom was rare for American artists. Her versatility and emotional range made her one of the best-selling female pop stars of her generation.

A Social Media Resurgence in Recent Years

In the digital age, Connie Francis found renewed fame among younger audiences thanks to social media platforms like TikTok and Instagram Reels. Her 1965 song “Pretty Little Baby” became a viral favorite, introducing her music to a new generation and reminding the world of her timeless appeal.

Four people in Florida have died from Vibrio vulnificus, a dangerous bacterium often dubbed the "flesh-eating" bacteria, as the state reports a total of 11 infections this summer. The deaths occurred across Hillsborough, Bay, Broward, and St. Johns counties, according to the Florida Department of Health’s latest update released on July 11.

Cases have also been identified in Duval, Escambia, Lee, Manatee, Santa Rosa, and Walton counties. While the numbers might seem small, health officials say the consequences can be devastating if the infection is not caught early.

What Is Vibrio Vulnificus?

Vibrio vulnificus is a naturally occurring bacterium found in warm saltwater or brackish water, which is a mix of salt and freshwater. It thrives particularly well during the hotter months, which is why infections spike from May through October. According to the Centers for Disease Control and Prevention (CDC), the bacteria is halophilic, meaning it needs salt to survive.

While rare, the infection can cause necrotizing fasciitis. It is a condition where flesh-eating bacteria could destroy the tissue under the skin, and can lead to death in just a few days if left untreated.

How People Get Infected?

According to Dr. Norman Beatty, an infectious disease specialist and associate professor at the University of Florida, as reported by WUSF, West Central Florida's NPR station broadcasting news, there are two main ways people typically contract Vibrio vulnificus.

“We can consume it through contaminated shellfish, specifically oysters,” Beatty said. If ingested, the bacteria can cause symptoms like nausea, vomiting, diarrhea, and abdominal cramps.

Also Read: 'Pretty Little Baby' Singer Connie Francis Passes Away At 87, What Happened To Her?

But the more dangerous and more common route, he explains, is through open wounds. “If someone with a cut or scrape enters brackish or saltwater contaminated with Vibrio vulnificus, the bacteria can enter the body through the skin and cause serious infection,” he warned.

Symptoms to Watch For

Symptoms often appear quickly; sometimes within hours of exposure. Early signs include redness, pain, and swelling around the wound. As the infection progresses, it can cause skin ulcers, blisters, and even tissue death. Systemic symptoms like fever, chills, and low blood pressure may also follow.

“A delay in treatment can lead to serious complications, including amputations or even death,” Dr. Beatty cautioned.

Who’s Most at Risk?

People with weakened immune systems, liver disease, or chronic health conditions are at greater risk of developing severe infections. But Dr. Beatty emphasized that even healthy individuals aren’t immune.

“I’ve seen otherwise healthy people who got a small cut while fishing or kayaking and ended up battling this infection,” he said.

How to Stay Safe?

With summer in full swing and more people spending time in and around water, doctors urge caution. If you have an open wound, avoid wading or swimming in warm seawater or brackish water. If exposure happens accidentally, clean the wound immediately with soap and bottled water. Covering healing wounds with waterproof bandages can also reduce the risk of infection.

If symptoms develop after being in such water or consuming raw seafood, particularly oysters, seek medical attention immediately and inform the doctor of your recent exposure.

A Persistent Health Threat

WUSF reports that in 2024 alone, Florida reported 82 Vibrio vulnificus cases and 19 deaths. Some of those were tied to flooding from Hurricane Helene, which caused contaminated water to spread inland. In past years, spikes in infections have been linked to major storms and hurricanes, including Hurricane Ian in 2022.

The CDC estimates around 80,000 Vibrio-related illnesses occur in the U.S. each year, with about 100 deaths, many of them preventable with timely care.

As Dr. Beatty puts it, “This is not a bacteria to take lightly. With increased awareness and a bit of caution, we can lower the risk and save lives.”