Ozempic, Wegovy, Mounjaro, and more such GLP-1 weight loss medication took people by surge. Everyone was jumping the bandwagon, this was especially the case in the US. In fact, US President Donald Trump also made these drugs cheaper. This was the trend, until people realized the other side of it. A study published in JAMA in January 2025 examined data from more than 125,000 adults with overweight or obesity and found a striking trend. Nearly 47 per cent of people with type 2 diabetes and 65 per cent of those without diabetes stopped taking GLP-1 weight loss drugs within a year. Among older Americans, drop-off rates appear especially high. Here are the four main reasons why.

The cost becomes unsustainable

GLP-1 medications are expensive, and insurance coverage is often inconsistent. Many older adults start these drugs with manageable co-pays, only to lose coverage later. Without insurance support, monthly costs can cross $1,000, forcing retirees on fixed incomes to stop treatment, even when the medication was working. The New York Times also noted a story of a 75-year0old woman, Mary Bucklew. She is a public transit retiree, who lives om Delware. She was paying just a $25 monthly co-pay through her health insurance plan to receive Ozempic for weight loss. She lost 25 pounds in six months, and gained more energy. However, her insurance company notified that the would no longer cover the drug, despite her arguing that this was absolutely necessary for her health.

"Far too many people who need obesity treatments still face cost and coverage barriers," said Ilya Yuffa, executive vice president and president for Lilly USA, in the announcement. "Today’s action underscores Lilly’s commitment to improving access across the obesity care landscape. We will keep working to provide more options, expanding choices for delivery devices and creating new pathways for access — so more people can get the medicines they need."

Side effects hit older bodies harder

Nausea, vomiting, diarrhea, constipation, bloating, fatigue, and headaches are common with GLP-1 drugs. Experts have pointed out that older adults are often more sensitive to these effects, especially if they are already prone to dehydration or have underlying kidney issues. For many, the discomfort outweighs the benefits.

Muscle loss raises safety concerns

Weight loss from GLP-1 drugs does not come entirely from fat. Studies cited by the American Heart Association show that a significant portion comes from muscle. Since muscle mass already declines with age, further loss can increase the risk of falls, fractures, and physical frailty in older adults.

Lack of personalized medical follow-up

Experts say many patients stop treatment because they are not closely monitored. Without tailored dosing, nutrition guidance, hydration support, and strength-preserving strategies, side effects worsen and benefits fade. With better supervision, some seniors might have stayed on these medications longer.

What are GLP-1 Drugs?

GLP-1 drugs, also known as GLP-1 agonists, were first developed for diabetes care. They work much like the body’s own GLP-1 hormone, which is released after meals to prompt insulin production. Those living with diabetes often do not make enough insulin to keep blood sugar steady. A GLP-1 medication boosts insulin release so blood sugar stays more stable. These drugs often support weight reduction as well.

For many people with diabetes, weight control plays an important role in managing the condition. GLP-1 drugs reduce hunger and help the stomach empty more slowly, creating a longer sense of fullness. This can lead to marked weight loss in people with or without diabetes.

Singer and actor Ray J has reportedly been admitted to a hospital in Las Vegas after experiencing what were described as “heart pains,” according to TMZ. The 44-year-old was hospitalized on January 6, with sources telling the outlet that the episode was connected to a severe case of pneumonia. As of Thursday afternoon local time, Ray J was still receiving medical care, TMZ reported.

According to the report, doctors conducted multiple tests, including chest X-rays and an echocardiogram, an ultrasound that checks how well the heart is functioning. The findings from these tests have not been shared publicly. Neither Ray J nor his representatives have released an official statement addressing his health or confirming his current condition.

Although the initial concern focused on possible heart-related issues, TMZ noted that pneumonia appears to be the primary cause behind his hospitalization. It is still unclear whether Ray J remains admitted or has since been discharged.

Ray J Hospitalised With Pneumonia, Heart Pain

This is not the first time Ray J has dealt with a serious pneumonia-related health scare. In late 2021, he was hospitalized after doctors initially suspected COVID-19 before later confirming pneumonia.

At the time, Ray J described the ordeal as life-threatening. “I thought it was over,” he told TMZ while recovering. “I started praying and knew God is good, so I just kept praying.” He later made a full recovery and was discharged after receiving oxygen support.

Despite reports of his recent hospitalization, Ray J has remained active online. He recently posted on Instagram to promote an upcoming event in Austin, Texas, scheduled for January 18 as part of his birthday celebrations. The post made no reference to any health concerns.

Pneumonia: What Is This Disease?

Pneumonia is an infection of the lungs that causes inflammation in the air sacs, known as alveoli. These air sacs may fill with fluid or pus, making breathing difficult and reducing the amount of oxygen reaching the bloodstream. The illness can be caused by bacteria, viruses, or fungi and often presents with symptoms such as coughing, fever, chills, and shortness of breath.

While pneumonia is usually treatable with medication, it can become severe in certain cases, particularly among older adults, young children, and people with weakened immune systems. Because of these risks, pneumonia remains a leading cause of hospitalization, according to the Cleveland Clinic.

Does Pneumonia Come With Heart Symptoms?

Yes. Pneumonia can trigger heart-related symptoms and complications. According to Healthline, patients may experience a rapid heart rate, chest pain, or increased strain on the heart. In more serious cases, pneumonia can worsen existing heart conditions or lead to complications such as arrhythmias, heart failure, or even heart attacks.

The intense inflammation caused by a lung infection places added stress on the cardiovascular system, making early diagnosis and treatment especially important, particularly for older adults or those with underlying heart disease.

How Common Are Pneumonia And Heart Symptoms?

Pneumonia is a common illness and is frequently linked to heart complications. Research cited by the National Institutes of Health shows that roughly one in four hospitalized adults with pneumonia develop major cardiac issues, including heart attacks, heart failure, or abnormal heart rhythms. These complications significantly increase the risk of death.

Heart disease also raises the likelihood of developing pneumonia, creating a two-way relationship between the two conditions. Inflammation from the infection can put additional pressure on the heart, especially in older patients and those with pre-existing cardiovascular problems.

Is Pneumonia With Heart Symptoms Fatal?

Yes, pneumonia accompanied by heart-related symptoms can be fatal. Cardiac complications are common and greatly increase mortality risk, particularly among older adults and individuals with existing heart conditions such as heart failure. The danger is highest in the period immediately following the infection.

Pneumonia places heavy stress on the heart and can trigger heart attacks, strokes, or a rapid worsening of existing heart disease, underscoring the importance of prompt medical care.

• Increased Mortality: Heart complications can make pneumonia more severe and raise the risk of death.
• Triggers Cardiac Events: Infection-related inflammation can lead to heart attacks, strokes, or irregular heart rhythms, even in people without prior heart disease.
• Exacerbates Existing Conditions: For those with heart failure or cardiovascular disease, pneumonia can cause sudden deterioration, leading to respiratory failure and death.

Performing short and intense exercises that last for about 10 minutes may significantly reduce the risk of colorectal cancer, a British study shows.

Researchers at Newcastle University have found that completing brief workouts increases the concentration of several small molecules in the blood that have previously been linked to reducing inflammation, improving blood vessel function and metabolism.

The findings, which were published in the International Journal of Cancer, also noted that even short bouts of exercise can influence the activity of genes that govern tumor growth and fight against cancer.

Dr Sam Orange, Senior Lecturer in Clinical Exercise Physiology at Newcastle University and lead study author, said of the results, "What’s remarkable is that exercise doesn’t just benefit healthy tissues, it sends powerful signals through the bloodstream that can directly influence thousands of genes in cancer cells.

“It’s an exciting insight because it opens the door to find ways that mimic or augment the biological effects of exercise, potentially improving cancer treatment and, crucially, patient outcomes.

“In the future, these insights could lead to new therapies that imitate the beneficial effects of exercise on how cells repair damaged DNA and use fuel for energy.”

How Does It Work?

Researchers had asked each volunteer to complete a short, intense cycling test that lasted about 10 minutes and collected each of their blood samples which were then meticulously analyzed.

After studying about 249 proteins, the experts found nearly 13 protein had increased in their blood flow after the short exercise including interleukin-6 (IL-6), which helps repair the DNA of damaged cells.

When these exercise-induced proteins were applied to colorectal or bowel cancer cells by the scientists in a lab, they discovered that these new proteins could alter the activity of over 1,300 genes, particularly those who were responsible for DNA repair, energy production and cancer cell growth.

As a result, they concluded that performing even small exercises can activate a set of genes in the body's cells that can support efficient use of oxygen and promote energy metabolism. Additionally, the British researchers also discovered that the cell genes which have been previously associated with rapid cell growth were switched off after working out, suggesting that this might aid in controlling cancerous growths in the body.

What Is Colorectal Cancer?

Colorectal or bowel cancer is a common cancer that forms in the tissues of the colon (large intestine) or rectum, often starting as non-cancerous growths called polyps that turn cancerous over time.

Despite being treatable and preventable, colorectal cancer is currently the second leading cause of cancer-related deaths worldwide. Over 70,000 new cases of colorectal cancer occur annually in India, making it the fourth most common cancer in the country.

Typical symptoms usually include :

• Blood in or on the stool
• Changes in bowel habits (diarrhea, constipation, narrower stools)
• Abdominal discomfort, cramps, gas, or pain
• Feeling that your bowel doesn't empty completely
• Weakness, fatigue, or unexplained weight loss

When temperature drops, so does the moisture even in your skin. This is what leads to a rash or allergies. In fact, with changes in temperature, and winters, our lifestyle changes too, this could also be the reason why we experience a winter rash, or allergies. To understand this better, Health and Me spoke to Dr Navjot Arora, Consultant Dermatologist, Dermaheal Skin and Clinic at Dwarka, Delhi, who explained that allergies and skin rashes tend to increase during winter due to both, environmental factors and changes in skin health. "Cold temperatures and low humidity levels reduce moisture in the air, leading to excessive dryness of the skin. When the skin becomes dry, its natural protective barrier weakens. This makes it more prone to irritation, inflammation, and allergic reactions."

Why Does Winter Weather Increase Chances Of Rashes And Allergies?

The doctor explains that during winter, people tend to stay indoors more, and it also increases their exposure to allergens like dust mites, mold, pet dander, and chemical fumes from heaters and cleaning products. "Limited ventilation and closed spaces allow these allergens to build up, triggering allergic responses and skin rashes, especially in individuals with sensitive skin or pre-existing conditions like eczema."

Cold weather also affects blood circulation to the skin. Reduced blood flow can slow down the skin’s repair process and weaken its defense against irritants and allergens. As a result, chronic skin conditions such as eczema, psoriasis, and contact dermatitis often worsen in winter, leading to itching, redness, flaking, and rashes.

Lifestyle Changes In Winter

Doctor also points out that during winters, our bathing habit changes. Dr Arora says, "Frequent hot showers strip away the skin’s natural oils, increasing dryness and irritation. In addition, wearing heavy woolen or synthetic clothing can cause friction, sweating, and contact allergies, particularly in skin folds, which can further contribute to rashes."

Common Symptoms Of Winter Rashes

• flushing
• swelling
• itching
• flaking skin
• sensitivity
• bumps
• blisters

If not treated well, or in time, it can develop into more serious health threat, especially if you have a family history of

• eczema or another type of dermatitis
• psoriasis
• rosacea
• allergies
• asthma
• sensitive skin

What Are The Cures To Winter Rashes And Allergies?

The rise in allergies and rashes during winter is largely linked to dry weather, indoor allergen exposure, and skin barrier damage. Maintaining proper skin hydration, avoiding harsh soaps, limiting hot water exposure, and wearing skin-friendly fabrics can help reduce the risk of winter-related allergies and skin rashes.

Moisturizers are usually the first line of care for dry skin because they help trap moisture and prevent further dryness. Apply them multiple times a day, especially after bathing or washing your hands. Thicker options like creams or ointments tend to keep skin hydrated longer than lighter lotions.

Petroleum jelly can also be effective, as it forms a protective barrier that seals in moisture. If you prefer to avoid petroleum-based products, alternatives like Waxelene or Un-Petroleum work in a similar way to reduce moisture loss.

Natural virgin oils, such as coconut oil, may help calm irritated skin and restore hydration. Use them on areas that are not acne-prone, and always do a patch test on a small area for 24 hours before wider application.

Oatmeal-based soaps or oatmeal baths can also help soothe dry, itchy skin. You can buy ready-made oatmeal soaps or add finely ground oats to a warm bath and soak for about 10 minutes.

For itching and inflammation, topical hydrocortisone creams, available over the counter or by prescription, may provide relief. Always follow the instructions on the label or use them as advised by a doctor.

Disclaimer: This is not a substitute for actual prescribed medicine. Please consult a doctor before you purchase any medicine or ointment for your rashes.