When we think of blood, we always think of it being red. But did you know that golden blood type also exist? It is world's most rare blood type, known as the golden or Rh-null blood type.

Why is it called "golden blood"?

Rh antigens in the red blood cells is what causes blood to appear as red, however, people with Rh-null blood lack these Rh antigens, giving the blood a slightly yellow color.

The proteins known as Rhesus (Rh) factors or antigens are completely absent in the red cells of people who have golden blood type. Less than 50 people in the world have this type of blood.

The Discovery of Golden Blood

In Ancient Greece, it was thought that only gods have golden blood. It was called Ichor, an ethereal fluid, which fabled to have immortal properties, but was toxic to mortals.

Then in 1961, a person with "golden blood" in Australia was discovered. This was an Australian Aborginal woman in 1961.

The Make-up of Golden Blood

Our red blood cells have sugars and proteins which are called antigens. These remain on the surface membranes. Depending on the mix of antigens present, blood is categorized into different blood types and so we have A, B, O, or AB blood types. The ABO system also has a distinction as Rh-positive which decides A+, B+, O+ and AB+ blood type and Rh-negative, which leads to A-, B-, O-, and AB-, this happens due to the presence or absence of "Rh-D" antigen.

What is the issue?

The biggest issue with golden blood type is that donations of Rh null blood type are incredibly scarce and very difficult to obtain. An Rh null person has to rely on the cooperation of a small network of regular Rh- null donors around the world if they ever need blood. While there are 50 people with the same blood type, only 9 of them are active donors for this blood group. This is what makes the blood type rare and also precious, another reason why it is called the "golden blood".

What kind of people have golden blood type?

The golden blood type appears to be caused by a genetic mutation (a spontaneous alteration in a gene). It is usually related with mutations in the RHAG gene, which codes for the Rh-associated glycoprotein. This protein is responsible for directing Rh antigens to the RBC membrane.

The RHAG mutation is frequently related with hereditary stomatocytosis. These people may experience long-term, moderate hemolytic anemia and accelerated RBC breakdown. The Rh-null phenotype can also be present in certain anemias that people are born with.

The following conditions may put you at a higher risk of the golden blood type:

Consanguineous marriage (marriage between cousins, brother-sister, or anybody who is a near or distant relative)

Autosomal genes (abnormal genes that have disease traits passed down through families)

Changes or complete deletion of certain genes, which are RHD and RHCE or RHAG

Can people with golden blood type donate blood?

Golden blood type can be donated as they have absence of antigens on RBCs, making the person a universal donor. The blood therefore can be donated to anyone with rare blood types within the Rh systems.

The blood due to its absence of antigens is great for transfusion and can be accepted by anyone who needs a transfusion without the risk of blood transfusion reaction. However, since the blood type is already rare, it is difficult to find a donor willing to donate it.

October 29 is observed as the World Stroke Day, annually. This day is recognized throughout the world and is observed to increase awareness of one of the leading causes of death and disability.

A stroke could happen to anyone, at any place, yet many people are not aware of the risk factors. This is why this day is observed worldwide, to bring attention on the warning signs and stroke prevention.

What Is The BEFAST Trick To Notice Stroke Signs?

Talking about warning signs, Dr Deep Das, a Neurologist at CMRI Kolkata says that the BEFAST trick could work best to notice for any early stroke system.

BEFAST stands for:

• B - Balance
• E - Eye or vision
• F - Face; Dr Das suggests to notice if the face becomes distorted
• A - Arm; the doctor suggests to check for weakness or loss of grip
• S - Speech; the suggestion is to look for slurred or unclear speech
• T - Time; the key is to act immediately without wasting anytime

"What makes a real difference is how quickly a stroke is diagnosed," notes Dr Das. The doctor also points out that with the advent of AI, the diagnosis could be done way faster. "Traditionally, stroke diagnosis and treatment have relied heavily on clinical expertise and imaging techniques, which could sometimes lead to delays in decision-making. AI has significantly enhanced these processes by providing rapid image analysis and predicting stroke outcomes with high accuracy."

World Stroke Day 2025: Theme

This year, the theme is 'Every Minute Counts'. The theme emphasizes on recognizing the symptoms and act fast on it, exactly what Dr Das also pointed out. On this, Dr Anjani Kumar Sharma, Director of Neuroscience at CK Birla Hospitals in Jaipur says, "World Stroke Day serves as a powerful reminder that stroke is a medical emergency that can affect anyone, anywhere, but it is also largely preventable." This is why every minute spent is crucial.

Dr Sharma says, "The acronym FAST, Face drooping, Arm weakness, Speech difficulty, Time to call emergency services — should be known to everyone." The doctor further adds that nearly 80% of strokes can be prevented through simple but consistent measures: controlling blood pressure and diabetes, avoiding tobacco and alcohol, eating a balanced diet, exercising regularly, and managing cholesterol. "Stroke is not the end," notes the doctor, "with timely medical intervention and focused rehabilitation, patients can regain independence and quality of life".

World Stroke Day Origin And Importance

The idea to celebrate a stroke day was initiated back in 2006 by global health leaders who recognized the importance of launching global movements and advocate against strokes. This has led to it being an important health event that focuses on educating the public on stroke warning signs, promoting prevention by keeping a healthy diet, as well as supporting survivors.

"As neurologists, we witness every day how stroke can strike suddenly, disrupting not only the life of an individual but also their family and community. Yet, what is heartening is that stroke is preventable, treatable, and increasingly survivable when recognized early," notes Dr Pushkar Gupta, Direct of Neurology at CK Birla Hospitals, Jaipur. The doctor says that the message for World Stroke Day is clear - to spread awareness and save lives.

BBC Morning Live’s Dr Punam Krishan has cautioned people who regularly use proton pump inhibitors (PPIs) such as omeprazole to manage heartburn, acid reflux, and indigestion. In the UK, one in four adults experiences acid reflux, especially after large meals, and many turn to PPIs to relieve symptoms. However, Dr Punam explained that long-term use of these medications could pose certain health risks and urged patients to have their prescriptions reviewed regularly.

Dr Punam, a practising NHS GP and resident medical expert on BBC’s Morning Live, is also a well-known health broadcaster and author of children’s books.

Omeprazole Warning For Acid Reflux

Speaking to hosts Gethin Jones and Helen Skelton, she began by explaining how acid reflux develops. “Acid reflux happens when stomach acid travels back up the food pipe,” she said. “We all have acid in our stomach, it plays a key role in breaking down food. A small valve, or sphincter, at the top of the stomach acts like a trapdoor to keep that acid in place. But when this valve becomes weak or too relaxed, the acid can flow back up the oesophagus, leading to that burning, heavy sensation people often describe.”

She added that large meals, alcohol, and lying down soon after eating can all make reflux worse.

When asked how reflux is usually treated, Dr Punam explained: “If you only experience symptoms occasionally, over-the-counter medicines like antacids or alginates, such as Gaviscon can help by neutralising stomach acid. They’re effective for mild cases and can be used as needed.”

“For ongoing discomfort, we prescribe proton pump inhibitors, or PPIs, like omeprazole or lansoprazole. These medicines are highly effective and have changed the way we treat acid reflux by targeting acid production directly at the source.”

Why Long-Term Use of PPIs Can Be Risky

Dr Punam warned that while PPIs are safe when used correctly, they are not intended for indefinite use. “These medications shouldn’t be taken unnecessarily or for long periods without medical review,” she said. “Extended use can slightly raise the risk of low magnesium or vitamin B12 levels and increase the likelihood of gut infections, particularly Clostridioides difficile, known as C. diff.”

She explained that C. diff is a bacterium that naturally exists in the gut but can overgrow when the balance is disturbed, sometimes causing persistent diarrhoea. “That’s a warning sign,” she said. “If you develop diarrhoea or notice changes in your bowel habits, speak to your doctor immediately. It’s very important to keep up with regular GP reviews if you’re on PPIs long-term.”

How Often Should People on PPIs See a Doctor?

If you are using omeprazole without a prescription, you should not continue for more than two weeks. See a doctor if:

• Your symptoms don’t improve after 14 days.
• Your symptoms get worse.
• Your symptoms return within four months of finishing treatment.
• You notice red flag signs such as difficulty swallowing, vomiting blood, or black stools.

While the NHS will be inviting many people to receive their Covid-19 vaccinations this year, a small group will need to skip it, even if they qualify for a free jab. Vaccines play an essential role in strengthening our body’s defences against viruses and are especially important during colder months.

This is because illnesses like Covid-19 continue to evolve, which can reduce the immune system’s ability to fight them over time. While the vaccine isn’t mandatory for everyone, it remains strongly advised for those more likely to develop serious illness from a coronavirus infection. Below is the full NHS list of people who are advised not to take the Covid jab.

The NHS generally recommends the Covid-19 vaccine for adults aged 75 and older, those living in care homes for older adults, and individuals with weakened immune systems due to medical conditions or treatments. However, for some, the vaccine may pose risks of adverse reactions, making it unsafe to receive.

Side Effects Of Covid-19 Vaccine

Not everyone who gets a Covid-19 vaccine will notice side effects, but NHS guidance outlines a few common ones, including:

• Aching muscles
• Headache
• Fatigue
• Soreness at the injection site
• Mild flu-like symptoms

These reactions are typically mild and tend to disappear within a week. The NHS recommends taking paracetamol to ease any discomfort during recovery.

Full List Of People Who Can’t Have The Covid Vaccine

The NHS continues to encourage everyone eligible for the vaccine to take it, especially during the winter months when infection rates usually climb. However, a few groups may need to delay or avoid the jab altogether, such as:

• People currently unwell with Covid-19
• Anyone running a high temperature
• Individuals who are feeling generally unwell
• Those at risk of a severe allergic reaction
• People who have recently recovered from Covid-19

If you have previously experienced a severe allergic reaction to the Covid vaccine or any other jab, your GP or vaccination provider may refer you to an allergy specialist who can assess your situation. In some cases, you may be advised to receive the vaccine in a specialist setting, such as a hospital, where any reaction can be managed quickly.

According to NHS guidance, this level of caution is usually only required for those with a history of anaphylaxis. However, even if you’ve experienced mild allergic symptoms before, such as hives, wheezing, or a rashyou may still be able to get vaccinated safely.

If you believe you currently have a Covid-19 infection, it’s best to wait until you’ve fully recovered before booking your jab. The NHS also clarifies that those who’ve recently had Covid-19 may not need the vaccine right away, as their immune system is already primed to recognise and respond to the latest strain.

You can find full details and updates on NHS guidance about the Covid-19 vaccine on their official website.