The latest annual report on cancer in the United States is a combination of good news and concern. While overall death rates from cancer continue to decline, an unexpected and troubling trend is emerging — more women are being diagnosed with cancer every year.

Published on April 21, 2025, in the journal Cancer, the 2024 Annual Report to the Nation on the Status of Cancer presents a complex image of progress and disparity. A collaborative effort of the National Cancer Institute (NCI), Centers for Disease Control and Prevention (CDC), American Cancer Society (ACS), and North American Association of Central Cancer Registries (NAACCR), the report provides a complete picture of U.S. cancer incidence and death trends between 2001 and 2022.

One of the brightest findings in the report is that cancer mortality rates have been falling steadily for men and women since 2001. The decline continued even in the early years of the COVID-19 pandemic.

The American Cancer Society credits this decline to a 32% reduction in cancer death rates between 1991 and 2019. This has meant an estimated 3.5 million deaths from cancer prevented, thanks to earlier diagnosis, changes in lifestyle, and medical advances.

Clerk of court records show this progress has included the decline of lung cancer death — one of the major factors in cancer-related deaths. The mortality rates among other smoking-associated cancers have significantly decreased as a direct result of declining smoking incidence over the years.

Better screening procedures have had a significant bearing on lowering death due to cancer. For instance:

Mortality from colorectal cancer has fallen by 52% in adults aged 50–75 years, largely as a result of regular screening.

Deaths from breast cancer have fallen by some 40% since the use of mammography became more common.

These results highlight the effectiveness of early diagnosis in enhancing survival and reducing disease burden.

Prevention Through Lifestyle Changes

As treatment advances are making front-page news, the report insists on the critical importance of prevention. Anti-smoking campaigns have dramatically reduced prevalence from more than 40% in the 1960s to only 14% nowadays, leading to important declines in tobacco-related cancers.

Public health initiatives urging healthier eating, more exercise, and weight control have also played a role in reducing risk. Remarkably, as many as 40% of cancers have been estimated to be preventable by such changes in lifestyle.

Impact of COVID-19 on Cancer Care

The report isn't afraid of the pandemic disruption to healthcare services. Cancer rates fell significantly in 2020, not as a result of genuine falls in disease but as a result of postponements in screening and diagnosis. By 2021, figures bounced back, suggesting that normal healthcare access resumed.

This volatility unearthed the compelling necessity for unwavering continuity of access to cancer care during even public health emergencies. The states exhibited uniform trends in the 2020 decline, apart from differing policy responses to COVID-19.

Why More Women Are Getting Diagnosed?

Even with the encouraging news on cancer mortality, concerning is the fact that cancer incidence in women has been increasing steadily. Between 2003 and 2021, the number of new cases in women ticked up slightly each year — except for a temporary decrease in 2020, when it happened during the pandemic. A number of explanations are probably to blame:

1. Obesity-Related Cancers Are on the Rise

The report identifies an increasing number of cancers associated with obesity, many of which disproportionately affect women. These include:

• Breast cancer in women
• Uterine (endometrial) cancer
• Pancreatic cancer
• Colon and rectal cancer
• Kidney and liver cancers

Rates of obesity have been consistently rising in the U.S., and women tend to experience distinctive metabolic and hormonal alterations (e.g., post-menopause) that can make them more susceptible to these cancers.

2. Enhanced Screening and Awareness

In part, the increase may be an artifact of better screening and female health awareness. More detection of early-stage cancer such as breast and cervical cancer — particularly in women who receive regular healthcare — is a healthy trend, albeit one that can temporarily boost incidence rates.

3. Environmental and Hormonal Factors

Endocrine-disrupting chemicals, hormone replacement therapy, and chronic exposure to estrogen (resulting from delayed childbearing or lower pregnancy rates) can cause elevated risk for specific cancers in women, such as breast and uterine cancer.

4. Racial and Ethnic Disparities in Cancer Diagnosis

The report points out that American Indian and Alaska Native women now have the highest cancer rate among all racial and ethnic female populations. This may be attributed to various factors — such as limited access to preventive care, socioeconomic challenges, environmental exposure, and genetic susceptibility.

Is There A Gender Disparities in Cancer Care?

The growing incidence of cancer among women underscores the necessity for gendered approaches to cancer prevention. While deaths are declining — a testament to progress — further action must be taken to:

• Combat the epidemic of obesity
• Provide access to early detection and treatment for all
• Target special hormonal and environmental risk factors in women

Healthcare systems need to respond to this changing environment with a comprehensive, integrated, and preventive strategy for cancer control that involves women from all walks of life.

The 2024 Annual Report on Cancer presents a reassuring vision of gradual reductions in cancer deaths due to decades of research, public health efforts, and medical progress. Yet the simultaneous increase in cancer incidence among women requires closer scrutiny.

Reading non-fiction books is not my cup of tea, while they are informative and important to read, when I read for pleasure, I want to immerse myself in a world that could never be. Reading fiction books like the Harry Potter series, Percy Jackson books and others like the Dragon Rider, were the reason I enjoyed reading. Often using these books as a means to escape difficult feelings, I never even realized how reading these books transformed my mental health, along with my perspective.

Reading plays an important role for your mental health; books offer numerous advantages for one's mental well-being. Whether the preference lies with short stories or lengthy novels, colorful picture books or digital formats, various forms of literature can provide valuable benefits. This piece will explore several key reasons why reading is so beneficial for mental health.

How Does Reading Impact Mental Health?

According to a 2022 PLoS One study, reading fiction can improve people's mental well-being. The researchers conducted five different studies to see how various ways of engaging with fiction affect individuals. These methods includes recalling past fiction reading experiences, being instructed to read fiction, discussing fiction in comparison to non-fiction, and discussing different types of fiction.

The research shows that books had a positive influence on people's mood and emotions. However, it appears that simply reading fiction might not lead to an immediate improvement in mental well-being. The brain seems to require a period of processing and understanding the story before positive effects can be observed.

Ways Reading Can Affect Your Mental Health

Mental Health First Aid England, a social enterprise that offers guidance and training for mental health in workspaces, explains that whether the preference lies with short stories or lengthy novels, colorful picture books or digital formats, various forms of literature can provide valuable benefits. Here are some ways it helps us.

Reading captivating books brings joy and immersion, making time disappear. Finishing a good story can evoke sadness or eagerness for more, highlighting reading's positive impact.

Reading as a Stress Buster

Engrossing oneself in a book for just six minutes can significantly reduce stress by lowering heart rate and easing tension, outperforming other relaxation methods.

Acts as a Coping Mechanism

Reading offers an escape from the real world, providing a coping mechanism, especially in childhood. This immersion can be transformative, influencing how we interact with the world.

Building Empathy

Reading fiction enhances empathy, improving the ability to understand others' feelings and thoughts, temporarily boosting this crucial social skill.

Keeping Your Brain Sharp

Lifelong cognitive activities like reading slow down memory loss and reduce mental decline in later life compared to less stimulating pursuits.

Finding Support and Healing in Reading Groups

Discussing books in reading groups can significantly improve mental health, aiding concentration, emotional understanding, self-awareness, and meaningful discussions.

Boost Your Sense of Control and Offer a Safe Space

Discussing books fosters a sense of control and independence, benefiting mental well-being. It provides a positive and safe way to process challenging topics.

Understanding Adulthood

Reading for pleasure in adolescence enhances academic performance, social engagement, and personal development, offering insights into adult life.

Boosting Your Intelligence

Research confirms that reading increases intelligence, leading to a larger vocabulary, broader knowledge, and improved verbal skills.

On the day of World Malaria Day, as we raise awareness on the dangers posed by this mosquito-borne disease, let's delve a bit deeper into how malaria is different from the other mosquito-borne diseases.

Dengue vs Malaria

Both malaria and dengue are transmitted by female mosquitoes and cause severe illness in humans. There are certain similarities between the two diseases and the mosquito species, which is why the patients and diagnoses are often confused.

As per the co-Principal Investigator, Dr Charles Guissou, for the Target Malaria, a vector control research alliance's Target Malaria Burkina Faso at the Institut de Recherche en Sciences de la Santé, "Dengue and malaria are two very different diseases caused by different pathogens and different mosquito species." “Misdiagnosis between malaria and dengue is common, and this can then contribute to inappropriate medical care.”

Every year, malaria causes 200 million cases worldwide, leading to 600,000 deaths. Many of these cases are from Africa, where children and pregnant women pay the highest price. The World Health Organization (WHO) has also reported that in 2022, Africa was home to 95% of malaria cases and 95% of malaria deaths. The global incidence of dengue has grown significantly in recent decades. Cases reported to WHO increased from 505,430 in 2000 to 6.5 million in 2023.

Dr Ajay Gupta, Head & Director - Internal Medicine, Max Super Speciality Hospital, Vaishali also points out the key differences between malaria and other mosquito-borne diseases. He says, "Malaria is caused by Plasmodium parasites, transmitted through the bite of infected Anopheles mosquitoes. In contrast, dengue, chikungunya, and Zika viruses are transmitted by Aedes mosquitoes. This distinction in the type of mosquito also reflects differences in peak biting times—Anopheles mosquitoes bite during nighttime, while Aedes mosquitoes are daytime biters."

"Another key difference lies in complications and disease progression. Malaria, especially caused by Plasmodium falciparum, can progress rapidly to severe illness with cerebral involvement, anemia, kidney failure, and even death if not promptly treated. Dengue, on the other hand, is known for a sudden drop in platelet count and risk of hemorrhage. Chikungunya commonly leads to prolonged joint pain, sometimes lasting weeks or even months after the infection clears," notes the doctor.

There is also a difference between how the mosquitoes that spread dengue and malaria.

The Aedes Mosquito

It is responsible for spreading dengue and has white stripes down the center of the thorax. It also has a resting position where its body is kept low and parallel to the ground, with the proboscis angled downward. It is slender, and the wings have distinctive white markings.

The Anopheles Mosquito

It is responsible for causing malaria and has long palps. It is dark in color and the resting position follows it abdomen at a 45-degree angle to the surface.

Zika Virus

Zika is a viral infection also transmitted by Aedes mosquitoes, which is the first difference from malaria, in the species of mosquito that causes it. As per the WHO, those with Zika virus do not tend to experience symptoms, and if they do, it includes rash, fever, conjunctivitis, and muscle and joint pain. The symptoms are also what makes it different. They appear from 3 to 14 days after being bitten.

Chikungunya

This is also caused by Aedes mosquitoes, and the symptoms usually appear within 4 to 8 days after infection. The symptoms include fever, joint pain, headaches, and nausea.

Yellow Fever

This is caused by Aedes and haemagogus mosquitoes. People who are infected with this virus do not get sick and experience only mild symptoms. As per the Centers for Disease Control and Prevention (CDC), 12% of people who have symptoms develop serious illness, which includes organ failure and jaundice.

The key difference between all other mosquito-borne diseases and malaria is the species of the mosquito that causes it. While all the others are caused by Aedes, malaria is caused by the Anopheles.

What Else Makes Malaria Different Other Than The Type Of Mosquito That Causes It?

Drinking Beer Could Increase Chances Of Infection

According to the scientists at the University of Emory, in their 2010 study, they found that beer produces an odour in your body that is irresistible to the malaria-carrying mosquitoes.

It Could Take Four Years To Develop Symptoms

There are rare strains of this disease which could in fact take months or even years to get diagnosed. In one of the rare cases, malaria was diagnosed four years later the individuals were infected, reported UK's The Telegraph.

Malaria And Its Connection With Snow White

In 1943, Disney was tasked with creating a film to promote public health awareness. The result? The Winged Scourge — a rather unusual PSA where the Seven Dwarfs learn how to fight off malaria-spreading mosquitoes.

Malaria Has Killed Four Popes, And At Least Eight Presidents Have Suffered From It

George Washington battled malaria, and the disease is also believed to have claimed the lives of Pope Leo and Pope Sixtus—just a few of its prominent victims.

Malaria And India

The doctor also points out that diagnosis and treatment also vary. "Malaria is typically confirmed with a blood smear or rapid diagnostic test and is treated with specific antimalarial drugs. There is no antiviral treatment for dengue, chikungunya, or Zika—management is primarily supportive," he says.

In India, we often see a spike in these illnesses during and after the monsoon season, However, malaria control efforts—such as early diagnosis, insecticide-treated bed nets, and vector control—have significantly reduced the burden in recent years.

"Preventive strategies like eliminating stagnant water, using mosquito repellents, and ensuring proper sanitation are universally effective. But recognizing the distinct nature of malaria is key to prompt diagnosis and management," notes Dr Gupta.

In 2022, about 1 in 5, which is around 702,880, people died due to cardiovascular diseases (CVD) in the United States. There are many factors around you that affect your heart health. Things like what food you eat, whether the area you live in is polluted or not and also what kind of lifestyle you lead. There are many risk factors for heart diseases like high blood pressure, high cholesterol levels or smoking, which are key risk factors according to the Centers of Disease Control and Prevention (CDC). The CDC explains about 47% of US citizens have at least one of these three risk factors.

Another risk factor could be the place you live in. A new study published in the European Society of Cardiology April 2025 revealed that the walkability of a neighborhood can play a big role for your cardiovascular health. The study revealed that individuals living in areas with low walkability had a 5% higher risk of developing CVD compared to those in very walkable neighborhoods. Interestingly, even in neighborhoods that improved in walkability over time, the risk of CVD remained about 5% higher for those who started in low-walkability areas, possibly due to the lasting effects of earlier sedentary habits.

What Makes A Neighborhood Walk-Friendly?

To figure out how walkable a neighborhood is, the researchers in the study looked at several things. They checked how many people lived in the area (population density), how many shops were nearby, if there were parks and green spaces, and if there were sidewalks to walk on. They also considered if different types of buildings were mixed together (like shops and homes), if there was good public transportation, and how well the streets connected to each other. All these things together helped them decide how easy it was to walk around in a certain neighborhood.

Researchers studied over three million adults who were at least 40 years old and didn't have any heart problems when the study started. The researchers kept track of how walkable each person's neighborhood was for 13 years. They also checked if the walkability of these neighborhoods stayed the same, got better, or got worse during that time.

The findings of this study support what doctors have known for a long time: moving your body is good for your health, especially your heart. What's interesting is that you don't need to do intense workouts to see the benefits. Even small amounts of activity, like walking your dog in a park or carrying your groceries home from the store, can make a difference. These little bursts of energy throughout the day can add up and help lower your risk of getting heart disease.

Should People Opt For More Walkable Places?

A report from 2023 from Smart Growth America found that less than 7% of people in America actually live in very walkable urban neighborhoods. Interestingly, studies have shown that minority groups often live in more walkable neighborhoods. However, these same groups are also more likely to suffer from heart and blood sugar problems. This might be because even in walkable areas, factors like safety, clean environments, and good sidewalks and parks might not be available in all neighborhoods.

Even if you don't live in a very walkable area, there are still things you can do to move more. You might need to get a little creative! You can try lifting weights or doing yoga while you watch TV. If you drive to the store, park a little further away so you have to walk more. Take the stairs instead of the elevator. Stand up and move around when you're on the phone, have walking meetings if possible, and make sure to get up and stretch every hour.