Are You At Risk For Early Stroke? Your Blood Type Could Hold The Answer
The blood group you belong to is more than just a marker to match your donation; it may have something telling you about your probability of acquiring certain diseases. A new study published in the Journal of Neurology notes that it can be made an assumption from your blood group by which you are most likely to have an early-onset ischemic stroke at the age under 60.
Although the factors like genetics, age, and lifestyle are the factors that best contribute to the risk of a stroke, this new research has really shed new light on how blood group can be considered as playing a pivotal role than ever thought.
A study suggests that an independent relationship exists between blood type A and an elevated risk for an early-onset ischemic stroke. Ischemic strokes are the presence of a blood clot in one artery, which causes blockage of blood flow to the brain, and about 90% of all stroke cases. The CDC suggests that in the United States, someone has a stroke every 40 seconds while one person dies from a stroke every 3.5 minutes.
This new research, hence, opens the possibilities that an earlier incidence of ischemic stroke in youth could be attributed to blood type A.
But it's worth remembering that blood type is just one of hundreds of risk factors, according to co-author Braxton Mitchell, PhD, MPH, a genetic epidemiologist at the University of Maryland School of Medicine. "In the grand scheme of things, it's a much smaller risk factor than others," he said. Other genetic, environmental, and lifestyle factors still determine stroke risk.
Study authors conducted a genome-wide association analysis, recruiting nearly 17,000 patients with stroke aged 18 to 59 years from 48 studies and more than 599,000 controls who never had a stroke history. The analysis was aimed at exploring genetic variants throughout the human genome in greater detail.
The ABO blood group possessed genetic differences, and the blood type A was the strongest risk factor for a stroke that occurred early in life. The possibility of having an early onset ischemic stroke was 18% higher among people with blood type A compared to the rest of the blood groups. Such a high risk could be associated with a higher susceptibility to blood coagulation, which is one of the most common causes of ischemic strokes.
On the other hand, individuals with type O blood have a 12% reduced risk of an early-onset stroke compared to other blood types. This is in-line with earlier research that has found people with type O blood are more likely to be at low risk for blood clotting inside their arteries, which could be the reason why their overall risk of having a stroke decreased.
Another blood group-the research looked at blood group B-for which a weak association is found with the onset of early and late stroke. However, the authors indicate that when sex and other risk factors are adjusted, no association between blood group B and increased stroke risk exists. In persons with blood group AB, there is no significant association discovered for having an elevated stroke risk.
While this study points to the effect of blood type, it is important to understand that blood type alone is not a strong predictor of stroke risk. Many other factors are comprised in this, including lifestyle, and most importantly, underlying health conditions. Age is one critical factor. According to the CDC, your risk for stroke doubles with each decade after age 55.
While strokes are more likely to affect people who are 65 years of age and older, one in seven strokes strikes people aged 15 to 49.
Thirdly, gender another factor that has been related to increased risks of stroke conditions. The female population is more prone to stroke compared to the male population and tends to have a worse outcome in terms of disability and death due to stroke.
It was recently indicated in the 2022 study that young women aged between 35-45 years had a 44% increased risk of ischemic stroke as compared to men aged between 35-45 years. Perhaps pregnancy or the use of birth control could be some of the factors behind the usual increased risk in women.
While the study does show a genetic element linked to blood type and stroke, other controllable factors are more important risks for stroke. Here are some steps you can take to reduce your total risk:
1. Control Blood Pressure: High blood pressure forms one of the most dominant risks for strokes. Control through regular monitoring, medication if required, and lifestyle modifications can prove to reduce this significantly.
2. Maintain a Healthy Weight: Being overweight increases the risk of stroke. Anyone can benefit from staying at a healthy weight and living a healthy lifestyle. A balanced diet and regular exercise can help you achieve and maintain a healthy weight and thus minimize your risk for stroke.
3. Reduce Alcohol Intake and Quit Smoking: Too much alcohol drinking and smoking are also significant risk factors for stroke. Cutting down on alcohol consumption and quitting smoking would be two very important lifestyle changes for anyone interested in being healthy.
4. Stay Physically Fit: Exercise is known to keep the heart healthy, reduce blood pressure, and promote a healthy weight all of which contribute to a decrease chance for stroke.
5. Monitor Your Cholesterol: It's a fact that high cholesterol builds up plaques in arteries, thereby increasing the chances of stroke occurrence. Fruits, vegetables, whole grains, and lean proteins are part of a heart-healthy diet that helps keep cholesterol at bay.
This research thus brings forward a new and enlightened perspective of the correlation between blood type and stroke risk, especially in younger ages. Although type A blood might have a propensity for developing early ischemic stroke, it is worth noting that this is just one of many factors responsible for developing a stroke.
Focusing on controllable lifestyle factors such as remaining within a healthy weight range, staying active, and managing blood pressure will help significantly reduce the chances of having a stroke regardless of the blood type.
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NHS has now issued a "flu jab SOS" as fears grow that the flu cases will add up to a brutal winter. While it is every winter that the flu strikes, this year, there is something different. A seasonal flu usually mutates in the summer and thus evade some of our immunity, which may have kicked in early flu season before. A seasonal flu is thus a type that has a history of being more severe.
All thanks to flu staying all round the year, flu experts have now said that they won't be shocked if this flu season becomes the worst flu season for a decade.
Professor Nicola Lewis, the director of the World Influenza Center at the Francis Crick Institute told BBC, "We haven't seen a virus like this for a while, these dynamics are unusual. It does concern me, absolutely. I'm not panicking, but I am worried."
Scientists have been able to track the evolution of influenza viruses because they mutate constantly, and thus the flu vaccines have to be updated every year to keep up. The evolution happens in a rhythm which is known as the "shift and drift". Most of the time the virus undergoes a minor change, however, every often there is also a sudden attempt for an abrupt shift as the virus keeps mutating.
Prof Derek Smith, who heads the Centre for Pathogen Evolution at the University of Cambridge, says seven mutations in a strain of the H3N2 seasonal flu have caused a rapid rise in cases involving this altered version of the virus.
Unusually, this spike happened outside the typical flu season, right in the middle of the northern hemisphere’s summer. “It will almost certainly spread worldwide, and quickly,” says Prof Smith. By September, once schools reopened and temperatures began to fall, cases started rising again.
Experts are still studying the exact impact of the mutations, but they likely help the virus slip past some of the immunity people have developed from past infections and vaccines. This makes it easier for the virus to infect and spread, which is why flu season has arrived early in the UK and countries like Japan.
If the virus spreads more easily, it doesn’t need to wait for cold winter conditions, when people stay indoors with closed windows, to trigger flu season. “We’re already far ahead,” says Prof Lewis. “This is likely to be a strong flu season.”
Using R numbers as a guide, the new mutated strain appears to have an advantage. Seasonal flu normally has an R value of about 1.2, but this year’s early estimates put it closer to 1.4. That means if 100 people were infected, they would typically spread it to 120 others, but this year that number could be around 140.
Professor Christophe Fraser, from the Pandemic Sciences Institute at the University of Oxford told BBC, "It's highly likely it's going to be a bad flu season and it's going to happen quite soon, we're already well into it. There are indicators that this could be worse than some of the flu seasons we've seen in the last 10 years."
In a normal flu season, about one in five people get infected, but that number could be higher this year, he warns. Still, there’s a lot of uncertainty around these predictions.
Many look to Australia for hints, since it saw its worst flu season on record, although it was dealing with a different H3N2 strain than the one spreading now.
Right now, the virus is circulating rapidly among children, especially in schools where germs spread easily. But the immunity of a 10-year-old is very different from that of an older adult, who has lived through many more flu seasons and carries different immune memory.
Because of this, experts will be watching closely as infections begin to move into older age groups in the coming weeks.
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India is facing a worrying rise in cancer cases, and top oncologists Dr. Gopal Sharma and Dr. Rakesh Kumar Agarwal, as reported in Times Of India have shred shedding light on the key problems. As per the doctors, factors like pollution, poor diet, obesity, and delayed diagnosis are the main drivers behind this surge, especially outside major cities. The battle against cancer, they stress, requires a holistic approach combining modern oncology, traditional medicine, and preventive care.
Air pollution is a major contributor to the rise in cancer. Dr. Gopal Sharma explains that fine particles like PM2.5 and PM10 cause chronic inflammation and oxidative stress, which slowly damages our DNA and can trigger tumor growth.
Dr. Rakesh Kumar Agarwal adds that the toxic mix of chemicals in polluted air, such as nitrogen oxides and benzene, acts as a silent carcinogen. These toxins don't just affect the lungs; they are linked to rising cases of breast, bladder, throat, and gastrointestinal cancers. Alarmingly, many of these new cases are appearing in non-smokers and at younger ages. The danger isn't limited to urban smog; indoor cooking smoke in rural households also poses a significant risk.
In rural India, cancer is often found too late, leading to much lower survival rates. Dr. Gopal Sharma points out that limited access to screening services, low awareness, and financial constraints prevent many people from getting checked until it’s too late. Cancers like breast and cervical, which are highly treatable when caught early, often go undetected until they are advanced.
Dr. Rakesh Kumar Agarwal highlights that many villagers first seek help from local healers or untrained providers, dismissing early symptoms as minor. Precious months pass during these delays, resulting in a flood of late-stage cases where curative options are limited. The clear solution, both doctors stress, is to take healthcare to the people using mobile screening vans and teleconsultations to bring care closer to communities.
Dietary habits play a significant role in cancer risk. Diets heavy in fried foods, processed snacks, and high salt can fuel metabolic and gastrointestinal cancers. Conversely, a traditional Indian diet rich in lentils, whole grains, and vegetables can help protect the body. The surge in obesity and diabetes further fuels cancer risk (like breast, pancreatic, and liver cancers) by creating metabolic imbalances and persistent inflammation. Tackling these metabolic conditions early is a powerful preventive tool.
Cultural taboos and stigma also lead to delayed diagnosis, particularly among Indian women. Fear of social stigma, family pressure, or concerns about marriage and infertility cause women to delay seeking help for breast and reproductive health issues. Oncologists believe that open dialogue, normalized through collaboration with schools and the media, is essential for timely detection.
For advanced treatment like immunotherapy and precision oncology, the main barriers are high cost, poor insurance reimbursement, and lack of infrastructure in Tier II and III cities. Broader insurance inclusion and government-funded programs are needed to make these treatments accessible.
The experts agree that cancer care should be a three-pronged approach: awareness, accessibility, and accountability. They propose integrating traditional modalities like Ayurveda, yoga, and mindful eating with evidence-based oncology to enhance patient compliance, reduce stress, and promote holistic recovery. Ultimately, the war against cancer will be won not just in labs and hospitals, but through better daily choices, cleaner air, healthier food, and smarter public policies.
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Every medicine has its own set of side effects, and Dr Dmitry Yaranov, a Russia-based cardiologist, who specializes in heart failure, advanced heart failure, heart transplantation, and mechanical circulatory support, says that some everyday drugs can pose hidden risks to the heart. His message is not meant to spark fear but to encourage awareness about medications we often assume are completely harmless.
Below are five categories of common drugs that Dr. Yaranov believes deserve more caution, especially for those with existing heart issues.
These are your everyday painkillers, which includes ibuprofen or naproxen. While they are go-to options for headaches, fever, or muscle cramps, Dr Yaranov says that its frequent use could strain the heart.
These drugs reduce inflammation by blocking certain chemical pathways, but they also make the body retain salt and water. This can:
Dr. Yaranov suggests discussing long-term or frequent NSAID use with a doctor, instead of using them casually.
While these drugs are life-saving, it may have side effects that could weaken the heart muscles. Dr Yaranov explains that drugs like doxorubicin or trastuzumab could also affect how well the heart pumps blood, which can lead to ardiomyopathy or heart failure.
Because of this, many cancer centres now include routine heart monitoring before, during, and after chemotherapy. The goal is to fight cancer without compromising long-term heart health.
Stimulants that contain amphetamines help improve focus and alertness, but Dr. Yaranov warns that they can also:
Elevate the risk of heart attack in people who have underlying heart issues
He stresses that misuse or unsupervised use is especially dangerous. Even for those who take them as prescribed, regular follow-ups with a doctor are important.
Managing diabetes could mean being on medicines for lifelong. Yaranov points out that older drugs like rosiglitazone can increase the risk of heart failure despite effectively lowering blood sugar. Because of these concerns, many doctors now prefer newer diabetes medications that also support cardiovascular health. However, patients should never switch or stop medicines without medical guidance.
Thanks to allergens and climate change, common cold now stays all around the year, which means you will be taking cold medicines frequently and for a longer stretch. These medicines contain pseudoephedrine that work by narrowing blood vessels to relieve nasal congestion, however, Dr Yaranov says that they can also:
For individuals with hypertension or heart disease, Dr. Yaranov advises avoiding these drugs or using them only after consulting a healthcare provider.
Dr. Yaranov’s core message is simple: even routine medications have side effects worth understanding. Being informed helps people protect their cardiovascular health, especially if they already have heart risk factors. The goal is not to avoid necessary treatment but to use medicines wisely and stay in regular touch with your doctor.
Note: This article is based purely on the remarks shared by Dr. Dmitry Yaranov. Health and Me does not recommend discontinuing or changing any medication without first consulting your doctor.
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