Novo Nordisk’s GLP-1 weight loss pill, Wegovy, has been approved in Australia for sale. An alternative to weekly weight loss injections, the Therapeutic Goods Administration (TGA) has cleared Wegovy, which contains semaglutide, the same active ingredient found in GLP-1 weight loss injections: Wegovy and Ozempic.The pill received TGA approval on November 3, 2026, expecting to reach the shelves by Christmas. It is prescribed to eligible adults to help manage chronic obesity along with lifestyle changes. It is also approved to reduce the risk of major cardiovascular events in eligible patients.Until now, Australians seeking GLP-1 medication for weight management have primarily had access to injectable formulations. The tablet offers a different approach. How Does The Wegovy Weight Loss Pill Work?Also read: Eli Lilly Can Continue Zepbound Ads Despite Novo Nordisk’s Claims Over Weight-Loss Drug ComparisonsThe new tablet contains semaglutide, a GLP-1 receptor agonist that mimics the action of the naturally occurring glucagon-like peptide-1 hormone.GLP-1 medications act on appetite regulation. They help users feel full, reduce cravings and slow stomach emptying, which can lead to lower calorie intake and weight loss.Unlike injectable Wegovy, which is administered once a week, this tablet should be taken every day.The TGA has approved four tablet strengths for sale: 1.5 mg, 4 mg, 9 mg and 25 mg. Treatment starts at a lower dose, which is gradually increased over approximately 16 weeks under medical supervision. The tablet also has specific use requirements. Patients must:Take it first thing in the morning on an empty stomach.Swallow it with a small amount of water.Avoid eating, drinking or taking other oral medications for at least 30 minutes afterwards.The fasting instructions are important because semaglutide is absorbed less efficiently when taken orally. So following that instruction is crucial as a 25 mg tablet has to achieve an effect comparable to the 2.4 mg weekly injectable Wegovy dose.Eligibility For GLP-1 Weight Loss Pill In AustraliaAlso read: Is ‘Ozempic Face’ Influencing The Beauty Industry? Global Cosmetic Brand Highlights A New Trend Amid GLP-1 BoomThe TGA approval covers adults who meet specific weight-related criteria. These include:Adults with obesity, defined as a body mass index (BMI) of 30 or higher.Adults who are overweight, with a BMI between 27 and 30, and have at least one weight-related health condition.These conditions may include high blood pressure, abnormal cholesterol levels, type 2 diabetes, fatty liver disease or other weight-related complications.The medication is also approved to reduce the risk of major adverse cardiovascular events in eligible adults with cardiovascular disease and those who are overweight or obese but don’t have diabetes.However, approval does not mean everyone meeting these criteria should automatically take the medication. A doctor must assess your health, medical history, and risks before prescribing it.Dr Brendan Hanrahan, an obesity medicine specialist at Brisbane's Wesley Hospital, welcomed wider access to the medication, saying GLP-1 drugs have "lived up to and exceeded the hype". However, he questioned whether BMI alone is enough to determine eligibility.He suggested waist circumference could offer some information about health risks, saying that some people may experience complications related to weight even when their BMI falls within the ‘normal’ healthy range.Side Effects And Risks Of Wegovy The oral pill does not eliminate the side effects associated with semaglutide. Common adverse effects include:NauseaVomitingDiarrhoeaConstipationAbdominal discomfortHeadacheFatigueDizzinessGastrointestinal symptoms can sometimes lead to dehydration, which may increase the risk of kidney problems.The TGA also warns about more serious complications, including acute pancreatitis and diabetic retinopathy. People with diabetes, particularly those with pre-existing eye disease, may need clinical monitoring.Semaglutide is not recommended during pregnancy, and people planning to become pregnant should discuss treatment and timing with their doctor.The TGA has also warned of depression and suicidal thoughts or behaviours linked with GLP-1 medications.