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We all at some point of our life thought if we had a delete button to erase the bad memories, haven't we? Now, this dream may come true. When I first came across this news, the first thing that came to my mind was the animated film The Boss Baby, where babies are sent from a baby corporate to ensure that people choose babies over pets. The baby is smart, witty, and works as a spy and once the job is done, the baby goes back to the baby corporate. When the baby is gone, the staff from the company comes with a magic wand and erases everyone's memories with the baby. It is like the baby never existed for the parents or the family in the first place. Now, scientists have discovered a way to potentially erase memories, though it is to weaken the hold of traumatic memories by reactivating positive ones.
A new study published in PNAS, titled Aversive memories can be weakened during human sleep via the reactivation of positive interfering memories suggests that erasing memory may become a real possibility. If so, this might be a breakthrough that could have wide-reaching impact for treating mental health conditions like PTSD, anxiety and depression.
The basis of the research is a simple but powerful idea: when you recall a negative memory, can you weaken it by immediately linking it with something positive? This theory was put to the test by an international team of scientists who worked with 37 participants in a controlled lab setting.
Participants were first asked to associate random, made-up words with disturbing or aversive images. These images came from recognized databases and included visuals such as injuries and dangerous animals. This created a mental link between the neutral words and negative feelings.
Once the participants have formed these unpleasant association, the next step is to sleep. This is the non-rapid eye movement or the NREM sleep. This is a crucial phase for memory consolidation. However, before this step, the researchers have attempted to "reprogram" half of the negative associations by linking the same nonsense words with pleasant images. It could be the peaceful landscapes or smiling faces.
When in the second night, the nonsense words were replayed to the participants as audio while they were in NERM sleep, their brain activity too was monitored. The monitoring happened using the electroencephalography (EEG). Interestingly, when positive images had been paired with the words earlier, the EEG showed a spike in theta-band activity. This is a brainwave that associates with emotional memory processing.
When the participants were asked to recall their memories the next day — and even several days later — a noticeable shift had taken place. Those nonsense words that had been "interfered with" by positive associations no longer triggered the same strong negative memories. In fact, participants were more likely to spontaneously recall the positive images instead. They also showed a more positive emotional bias when evaluating those memories.
In the researchers’ words, the study demonstrated that “a noninvasive sleep intervention can thus modify aversive recollection and affective responses.”
While the findings are promising, the researchers also noted that this was a controlled laboratory experiment. The emotional impact of viewing upsetting images in a lab is not the same as experiencing real-life trauma. True traumatic memories, especially those tied to lived experiences, may be much more resistant to this kind of memory editing.
That said, this approach builds on earlier findings that the brain naturally replays memories during sleep to reinforce them. If this process can be gently influenced — perhaps even without the sleeper knowing — it could someday become part of therapy for those struggling with difficult memories.
While the research still is in its early stage, it does add to the idea that our brains are not static storage banks. “Our findings open broad avenues for seeking to weaken aversive or traumatic memories,” the researchers said.
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Diseases can often have different effects on men and women due to obvious biological differences as well as hormonal- between the genders like the levels of certain hormones as well as the body's capacity to do certain tasks, etc. While conditions like diabetes and high blood pressure can also have a different effect on them. There are also other factors like psychological factors like men ignoring their health. A survey done by the Cleveland clinic showed that 65% of men avoid medical care for as long as they can, 44% men do not see a primary care provider regularly as 49% admitted that they do not keep up with a healthy diet.
A new study published in the PLOS Medicine journal reported that men are more likely to die from high blood pressure, HIV/AIDS and diabetes than women. The study revealed that this higher mortality rate appears to be linked to men being less likely to seek and consistently engage with medical care for these conditions.
One of the points highlighted in the study was that interestingly, men and women are each equally susceptible to the diseases. So the problem did not lie in a genetic or biological reason, it was rather the fact that men did not receive the proper treatment needed for their conditions. The key difference lies in what happens after a diagnosis. Men, for various reasons, appear less likely to actively participate in their healthcare, which can mean delaying doctor visits, not adhering to medication schedules, or not prioritizing regular check-ups. This difference in engagement has serious consequences for their long-term health outcomes.
Given these findings, researchers are emphasizing the urgent need to find better ways to encourage men to take a more active role in looking after their health. This includes promoting the importance of preventive care, so men are more likely to get regular screenings and catch potential problems early. It also means addressing the barriers that might prevent men from seeking medical attention when they need it and ensuring they feel comfortable and supported in engaging with healthcare services consistently over time to manage conditions effectively.
Researchers involved in the study highlights a crucial point: the medical world needs to recognize that men and women often experience and deal with their health in different ways. Healthcare providers need to move beyond a one-size-fits-all approach and develop strategies that are sensitive to these gender-specific behaviors and attitudes towards health. This might involve tailoring communication, making services more accessible and appealing to men, and designing treatment plans that better align with their lifestyles and preferences to improve adherence and ultimately lead to better health outcomes.
The research also uncovered that the primary factors contributing to health problems can sometimes differ between men and women. For example, in a large majority of the countries studied, men were significantly more likely to be smokers, which is a major risk factor for developing high blood pressure.
On the other hand, women in most countries had higher rates of obesity. These different risk factors, combined with the observed differences in how men and women seek and engage with healthcare services, help to explain the concerning disparities in death rates from these common diseases. Understanding these variations is a vital step towards creating more equitable healthcare for everyone.
Credits: Canva
Spring is a beautiful time, but it often brings along runny noses, sneezing, and congestion. These symptoms can easily be mistaken for either a cold or seasonal allergies. Both share overlapping traits, but they stem from entirely different causes. A cold is caused by a virus, making it infectious, while seasonal allergies are your immune system’s reaction to harmless substances like pollen.
In many parts of the world, it is also the time when seasonal changes are occurring. With shorter springs, longer summers, or the transition in between, pollen is everywhere. However, it does not mean that other common virus and bacteria are gone. So, how do you differentiate between them, especially when you get sick? How do you know when you have a cold or an allergy.
Let us check this out!
Seasonal allergies, also known as hay fever or allergic rhinitis, happen when your immune system mistakenly sees pollen as a threat and releases chemicals like histamines to fight it. This overreaction leads to sneezing, a runny or stuffy nose, itchy eyes, and sometimes throat irritation.
Different types of pollen trigger allergies depending on the season. In spring, tree pollen is the main culprit. As the year progresses, grass and weed pollens take over. Due to rising global temperatures, allergy seasons are starting earlier and lasting longer than before.
A cold is typically caused by viruses like the rhinovirus and is more common during seasonal transitions. It spreads easily through the air or by touching contaminated surfaces. Cold symptoms often include a sore throat, fatigue, congestion, sneezing, and a runny nose. You may also experience body aches and a mild fever.
Unlike allergies, which persist for weeks or even months, colds usually last between three and seven days for most healthy individuals.
Despite their similarities, colds and allergies have a few clear distinctions:
Duration: A cold is short-lived, usually resolving within a week. Allergies persist throughout the pollen season.
Itchiness: Allergies commonly cause itchy eyes and throat. Colds may bring soreness but rarely itchiness.
Fever and Body Aches: Colds can come with mild fever and aches. Allergies do not.
Contagiousness: Colds are infectious; allergies are not. If you’re sneezing and spreading droplets, you could pass on a cold.
Mucus Color: Colds may lead to yellow or green mucus. Allergy mucus tends to stay clear.
There’s no quick fix for a cold, but you can ease symptoms by:
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Susana Moreira, a 41-year-old woman from Santiago, Chile, has lived with a debilitating form of muscular dystrophy since childhood. She was diagnosed with this condition at the age of 8. Her condition has been progressive since then. As a result, she was bedridden for over 20 years. She was once able to move, but can now no longer walk, bathe, or care for herself.
Her muscles have continued to weaken and she is expected to eventually lose the ability to speak and breathe without help.
As per the National Institute of Neurological Disorders and Stroke, muscular dystrophy or MD refers to a group of genetic diseases that cause progressive weakness and degeneration of skeletal muscles. These disorders vary in age of onset, severity, and the pattern of affected muscle. However, one thing that is definite is that this condition is progressive in nature.
As per NIH, it affects by weakening the muscles. Muscles are made of thousands of fibers and these fibers contain cells surrounded by an outer layer of membrane. Muscle fibers that make these individual muscles are bound together by connective tissue. Muscles are activated when an impulse, or signal is sent from the brain. What happens in MD is the protective membrane of the muscle is damaged and the muscle fibers begin to leak protein creatine kinase and take excess calcium. This damages the muscle fibers and then causes the fibers to die, and thus leads to progressive muscle degeneration.
Moreira, is also facing the same condition, which will eventually make her unable to live with dignity. Therefore, she wants to be able to choose a dignified death, though euthanasia.
However, euthanasia and assisted dying are currently illegal in Chile. Her deeply personal plea has reignited a national conversation and become a symbol of the push for legal reform.
Chile’s debate over euthanasia is not new. In 2021, the Chamber of Deputies approved a bill to allow both euthanasia and assisted suicide for adults suffering from terminal or incurable illnesses. But the legislation has since stalled in the Senate.
If passed, Chile would join countries like Belgium, Spain, Canada, and the Netherlands in legalizing both practices. In Latin America, Colombia already allows euthanasia, and Ecuador recently decriminalized it, though regulations are still pending.
Confined to her home, Moreira spends her days reading, watching movies, and playing video games. Outings are rare due to the pain caused by sitting in a wheelchair for too long. In a letter to President Gabriel Boric, she urged him to support the bill and shared her fears about reaching a stage where she could no longer communicate her wishes.
President Boric responded publicly, calling the bill “an act of empathy, responsibility and respect,” and promised to prioritize it in his final year in office. However, political turmoil has since pushed the issue to the sidelines.
While Chile was once considered one of Latin America’s most conservative nations, attitudes toward euthanasia have shifted. A 2024 Cadem survey found that 75% of Chileans support euthanasia. Another study by the Center for Public Studies reported 89% support for allowing it either always or in special cases.
Supporters argue the law would offer people suffering from terminal conditions a humane and legal option. Critics, however, say better access to palliative care must come first. Chile passed a law in 2022 guaranteeing palliative care, but experts argue its implementation is uneven.
The debate has also been shaped by other moving stories, such as that of Valentina Maureira, a teen who pleaded publicly for euthanasia in 2015 but was denied and died shortly after.
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