It starts innocently enough. Maybe it’s a wrinkle forming at the edge of your eyes or the first sign of aching joints after a long day. For many, ageing creeps in slowly, until one day, it becomes the loudest voice in the mirror. The desire to hold on to youth—to remain vibrant, sharp, and wrinkle-free—has fueled a booming global market of anti-ageing solutions. From collagen powders and NMN capsules to calorie-mimicking compounds, anti-ageing drugs and supplements promise to slow time’s march forward.

But here’s the uncomfortable question: What if your quest to look or feel younger is silently speeding up your biological decline? As the anti-ageing industry grows, medical experts warn that some of these interventions might come with unintended, even dangerous, consequences.

The answer is complex. While some anti-ageing drugs and supplements may offer genuine health benefits, others carry hidden risks, especially when used unsupervised or in combination with other medications.

Whether it’s reversing wrinkles, easing joint pain, or stimulating a sluggish metabolism, anti-ageing drugs are now everywhere. The global market for these supplements and therapies is set to skyrocket over the next decade. But effectiveness aside, there’s growing concern over how these substances interact with the body’s internal systems—especially when taken without medical guidance.

The term "anti-ageing" itself is increasingly under scrutiny. It suggests a battle against the inevitable. As a prominent U.S. beauty magazine, acknowledged in its decision to ban the term from its editorial vocabulary, the phrase carries unrealistic and potentially harmful connotations. Instead, terms like "healthy ageing" or "pro-ageing" are gaining ground—offering a more balanced and science-based lens to look at ageing gracefully.

We spoke to experts to discuss the real and potential reasons about the why and how of anti-ageing drugs and their effect on the human body.

Why Are Anti-Ageing Drugs So Popular?

Anti-ageing treatments encompass a wide range of products: from over-the-counter creams and oral supplements to prescription medications and injectable therapies. Popular compounds include antioxidants like glutathione and vitamin C, hormonal agents such as testosterone and growth hormone, and metabolic modulators like metformin and rapamycin. Many of these are marketed with bold claims—promising not just cosmetic improvements, but also enhanced vitality and longevity.

The science behind some of these products is promising. For example, metformin, a drug widely used for diabetes, has been shown in some studies to reduce inflammation, slow organ decline, and lower the risk of age-related diseases. However, the evidence that it—or any other anti-ageing drug—can reliably extend human lifespan remains inconclusive.

Do Anti-Ageing Drugs Mimic Caloric Restriction?

Many anti-ageing drugs work by mimicking caloric restriction or altering key metabolic pathways, a mechanism known to extend lifespan in lab animals. But this doesn’t mean they’re risk-free for humans, especially those with underlying conditions.

“Some anti-ageing drugs change the manner in which the body uses energy, similar to the effect of consuming fewer calories,” explains Dr. Vinay Aggarwal, Past National President of the Indian Medical Association. “While this will cause good ageing, it may put additional stress on the heart, especially in adults with pre-existing illnesses. The heart may be forced to labor harder or evolve to accommodate new energy demands, which may lead to fatigue, weakness, or arrhythmia in some individuals.”

In short, while these drugs may slow down some processes associated with ageing, they might also increase cardiovascular workload—potentially raising the risk of heart complications in certain users.

What Red Flags Should You Watch for When Self-Medicating?

The trend of self-medicating with anti-ageing supplements is growing, but it can be dangerous. Beyond prescription drugs, many people turn to over-the-counter anti-ageing supplements with little medical oversight. This self-medicating trend can pose a serious health threat.

“Individuals who use anti-ageing supplements without consulting a physician ought to be watchful for symptoms such as persistent fatigue, insomnia, dizziness, rapid heartbeat, or stomach upset,” warns Dr. Aggarwal.

“Mixing various supplements also elevates risks to overall health. If one starts to feel sick or notices some strange change since beginning such products, they should consult a physician immediately.”

The lack of regulation in the supplement industry means consumers are often unaware of what they’re ingesting—or how it interacts with other medications or pre-existing conditions.

Dr. Aggarwal shares that these warning signs may indicate that the body is not responding well to the supplement. He also cautions that mixing various supplements increases health risks, and if you start to feel unwell or notice unusual changes after beginning such products, it’s crucial to consult a physician immediately.

Could Anti-Ageing Drugs Destabilize Your Cardiovascular System?

The cardiovascular system is particularly vulnerable to the effects of anti-ageing drugs. Dr. S.S. Sibia, Cardiologist & Director at Sibia Medical Center, Ludhiana, explains, "“Hormonal, metabolic, or cellular repair agents may sometimes produce an undesirable effect on blood pressure control or stress-induced heart function."

“Uncontrolled use, especially in those with underlying conditions, can lead to disruption of autonomic balance or vascular function, precipitating risks like hypertension or hypotensive attacks.”

The mechanisms behind these risks are still being studied, but early research indicates that these compounds can disrupt the heart’s electrical signaling or alter vascular tone, both of which are critical to stable blood pressure and rhythm.

“Some anti-aging therapies can interfere with cellular energy metabolism or signaling pathways that control heart function,” Dr. Sibia adds.

“This can be interfering with the electrical signal of the heart or changing constriction of blood vessels. Thus, some people might develop irregular heart rhythms or changes in blood pressure, particularly with long-term or unmonitored therapy.”

How Do Dermatologists Evaluate the Side Effects of Anti-Ageing Drugs?

Beyond the heart, the skin and other organs can also be affected by anti-ageing treatments. Dr. Chandani Jain Gupta, MBBS & MD, Dermatologist & Aesthetic Physician at Elantis Healthcare, New Delhi, explains that side effects are assessed through clinical trials, dermatology tests, and ongoing post-launch monitoring.

In the dermatology world, anti-ageing topicals—ranging from retinoids to hormone creams—have long been popular. But even here, caution is advised.

“Side effects are evaluated on clinical trials, dermatology tests, and post-launch monitoring,” says Dr. Chandani. “Common issues include irritation, pigmentation, or potentially systemic impact. Safety profiles are dependent upon dosage, duration, patient profile, and ingredient interaction.”

With long-term usage, the skin might not always respond positively—especially with unregulated or steroid-infused products.

“The safety line is the point at which benefit is greater than risk,” Dr. Gupta adds. “Long-term products must be okay’d by dermatologists, clinically proven, and contain no harmful ingredients like steroids or unregulated hormones. Regular skin checkups and halting at signs of unfavorable reaction guarantee safety.”

A major challenge with anti-ageing supplements is the lack of stringent regulation. Unlike prescription drugs, many supplements are not subject to rigorous safety or efficacy testing before reaching consumers. This opens the door to contamination, inaccurate dosing, and potentially dangerous interactions with other medications. Introducing multiple supplements at once can create a “pharmacological pandora’s box,” increasing the risk of adverse reactions and drug interactions.

Diet vs. Drugs: Is There a Safer Path to Healthy Ageing?

Emerging research suggests that lifestyle factors—especially diet—may have a more profound and safer impact on ageing than drugs alone. Dietary patterns, particularly protein and energy intake, can influence cellular health and longevity more fundamentally than most pharmacological interventions. While drugs may dampen some metabolic responses, they rarely reshape the underlying cellular machinery the way diet can.

There’s no denying the allure of anti-ageing treatments. Who doesn’t want to look and feel their best as they age? But experts agree: there’s no magic pill or serum that can completely halt time.

More importantly, the goal shouldn't be to resist ageing—but to age well. That means making informed choices, consulting healthcare professionals, and prioritizing long-term health over short-term gains.

Some drugs and supplements may offer healthspan benefits, but the risks—especially to cardiovascular health—are real and can be life-threatening if misused or taken without medical oversight. If you are considering anti-ageing drugs or supplements, consult a qualified physician, monitor for side effects, and be wary of unproven claims or off-label uses.

“Health is Wealth” is something we all teach our kids so that they learn to put themselves first, however many times they fail to learn it as we ourselves do not follow it.

While we are constantly urged to take care of our health above anything else, it is a message not many of us take seriously. Many people in the UK are putting their health on the back burner, claiming they're simply too busy.

A recent study reveals that one in five Brits are neglecting their own well-being, often skipping important appointments like eye exams, dental visits, and doctor's check-ups. In fact, three-quarters of people have either missed or postponed a health appointment because their schedules were too packed.

Why Are We So Busy?

The main culprits for these missed appointments seem to be work demands and childcare responsibilities. On top of that, the sheer stress of arranging the appointments themselves is another big reason adults avoid necessary blood tests or eye exams. This research, commissioned by Specsavers for Glaucoma Awareness Week, aims to shed light on glaucoma, often called the "silent thief of sight."

What is Glaucoma?

Glaucoma refers to a group of eye diseases that can lead to vision loss and even blindness. It does this by harming your optic nerve, which is like a cable at the back of your eye that sends images to your brain.

The tricky part about glaucoma is that its symptoms often begin so slowly you might not even notice them. This is why it's often called the "silent thief of sight." The only way to truly find out if you have it is by getting a thorough eye exam where your pupils are dilated.

While there's no cure for glaucoma, catching it early and starting treatment can often stop the damage and help protect your vision from getting worse.

Don't Wait for Symptoms

A spokesperson highlighted that it's easy to push check-ups aside when you feel fine and life is hectic. However, conditions like glaucoma can develop slowly without any noticeable symptoms. By the time you notice an issue, "irreversible damage" might have already occurred. That's why it's crucial not to wait for symptoms to appear; regular check-ups can help protect your long-term health.

Initially, glaucoma usually has no noticeable symptoms. This is a big reason why about half of the people who have it don't even know it.

Over time, you might slowly start to lose your vision. This often begins with your side (peripheral) vision, especially the part closest to your nose. Because this happens so gradually, many people don't realize their vision is changing at first. As the disease worsens without treatment, you may begin to notice significant blind spots and, eventually, it can lead to complete blindness.

Simple Tasks Often Overlooked

The study also found that busy adults often neglect other simple health tasks due to lack of time. These include getting a full night's sleep or drinking enough water. A significant number of people (one-fifth) admitted they've been so focused on work that they haven't taken proper screen breaks or even moved from their seats for long periods.

Among those who don't prioritize their own health, 28% put their children's needs first, while 19% prioritize housework. Sadly, over a third confessed that only a health scare or a clear symptom would finally push them to book a delayed check-up. Many understand the need for appointments but find them easy to forget.

Making Health a Priority

Many Brits believe that easier booking systems (four in ten) or simply more time in their day (a third) would help them focus more on their health. Specsavers emphasized that even though schedules are busy, ignoring eye care isn't an option. A quick eye check every couple of years can protect you from serious long-term problems. Your vision is incredibly valuable and deserves your attention.

Sleep is one of the most important pillars of health. How much you sleep, what times as well as how well you sleep are things that heavily affect your body and lifestyle. Many people think sleep is something they can always recover from. Stayed up too late but still going to work early in the morning? Or you slept on time but woke up due to some issue, making you unable to sleep the rest of the night. These are issues we have all faced, and we figure that we’ll sleep when our day ends.

However, this is not an issue to be taken lightly, as researchers found that lack of sleep can essentially shorten your lifespan.

A 2025 study published in Springer Nature Link have found a clear link between how long you sleep and your risk of dying. They say there's a "golden window" of two hours that most people should aim for to stay healthy and avoid bad consequences. To figure this out, scientists looked at almost 80 past studies, which included information from over two million people, giving them a lot of data to understand sleep patterns better.

Dangers of Too Much (or Too Little) Sleep

The research shows risks for both sleeping too little and sleeping too much. If you regularly sleep for more than nine hours each night, you could face a 34% higher risk of death. On the other hand, those who sleep for less than seven hours faced a 14% increased risk of dying. This ideal sleep range matches what health groups like the NHS suggest for most healthy adults, though it's noted that everyone's needs can be a bit different based on things like age.

Why Long Sleep Might Be a Warning Sign

The study's authors, from a university in Hungary, think that sleeping too much might actually be a sign of hidden health problems. For example, if someone has a heart issue that hasn't been found yet, it could make them feel extra tired, causing them to sleep more. This means the higher risk isn't just from the sleep itself, but possibly from an underlying sickness. Interestingly, women who slept over nine hours had an even higher risk – 41% greater – compared to women who got a normal amount of sleep.

Perfect Amount: 7 to 8 Hours

After looking at all that information from millions of people, the research strongly points to sleeping between seven and eight hours as the best amount for staying healthy. This time seems to be just right for your body and mind to rest and work well. However, the researchers did notice that different studies on long sleep times sometimes showed slightly different results. This means we might need more research to fully understand all the ways sleeping too much can affect our health and specific causes of death.

Why Good Sleep Matters for Everything

A good night's sleep is absolutely essential and does much more than just make you feel rested. It helps your mental health, gives you enough physical energy for your day, and keeps your brain sharp so you can think and focus clearly. Health experts also warn that ongoing sleep problems can negatively affect your relationships, social life, and even simple daily tasks. These continuous issues can make you feel constantly tired, lead to eating more, and make you less productive at work or school.

Can You Recover Lost Sleep?

Recovering lost sleep is not as simple as you may think it is. The more hours you lose, the more you accumulate sleep debt. Sleep debt, according to the Sleep Foundation, is the difference between the amount of sleep you need and how much you are actually getting.

While short naps (10-20 minutes) can refresh you, and sleeping in on weekends might feel good, they often aren't enough for true recovery. Research shows it can take four days to bounce back from just one hour of lost sleep, and even longer to fully erase "sleep debt" and restore your body's normal function. Your brain needs more than a weekend to recover fully from ongoing sleep restriction.

Celebrities go through extreme amounts of scrutiny, constantly living under pressure and having to stomach all their personal feelings in order to continue their work. Olivia Munn is no stranger to this feeling. The American actress recently opened up about struggling with an uncommon condition that was triggered due to a paparazzi shot.

She revealed she lives with trichotillomania, a lesser-known mental health condition. This news comes after her public battle with breast cancer, highlighting her continued openness about her health journey.

“I did the horrible thing, which was to read the comments... And they were like ‘I think she set this up!’” In a recent episode of ‘Armchair expert’ podcast, Munn shared that her trichotillomania began after an incident with paparazzi between 2009 and 2010 when she was dating Chris Pine. The insensitive comments turned out to be a trigger for her, and she explained it was the beginning of her condition.

What is Trichotillomania?

Trichotillomania, also called trich or TTM, is a condition where people have strong, repeated, and uncontrollable urges to pull out their hair. This hair can come from their scalp, eyebrows, or other body parts. Munn explained that the urge to pull can be quite intense and it is a sensation that feels like “oh this eyelash feels like its going to come out, even though it is not”. Once you pull it, she details, there is a small second of pain, then satisfaction followed up with immediate regret.

The National Health Services UK explains that people with trichotillomania often feel a certain sensation. They feel a lot of tension building up until they pull, and once they do, they often feel a sense of relief. Sometimes, hair pulling happens when someone is stressed, but it can also happen without them even thinking about it. While most people pull hair from their head, some also pull from their:

• Eyebrows
• Eyelashes
• Genital area
• Beard or mustache

Bald patches may appear unusually shaped and affect one side of the head more than the other. Trich can lead to feelings of shame and low self-esteem, often causing individuals to try and conceal their condition.

What Causes Trichotillomania?

The exact causes of trichotillomania are not entirely clear, but potential factors include:

Coping mechanism

For some, pulling hair might be a way to deal with strong emotions like stress or anxiety. It could be a kind of self-soothing behavior.

Chemical imbalance

There might be differences in the brain's chemicals that affect how a person controls urges or handles rewards, making it harder to stop pulling hair.

Hormonal changes

Changes in hormone levels, especially during puberty when the condition often starts, could also be a factor.

Genetics

If someone in your family has trichotillomania, you might be more likely to develop it too, suggesting that genes could play a part.

Can Trichotillomania Be Treated?

The main way to treat trichotillomania is through a therapy called habit reversal training, which is a type of cognitive behavioral therapy (CBT). This therapy focuses on helping you replace the urge to pull your hair with something harmless. It typically involves keeping a diary to track when and where you pull your hair, which helps you identify and understand your triggers – the specific situations or feelings that make you want to pull.

Once you know your triggers, you can work on replacing the hair-pulling action with a different, less harmful behavior, like squeezing a stress ball or making a fist. Support from loved ones is also a key part of this process, providing encouragement as you work to change the habit. Other self help tips according to NHS are,

• Squeeze a stress ball or similar object.
• Form a fist and tighten arm muscles.
• Use a fidget toy.
• Wear a bandana or a tight-fitting hat like a beanie.
• Take a soothing bath to reduce stress or anxiety.
• Practice deep breathing until the urge subsides.
• Exercise regularly.
• Apply plasters to fingertips.
• Cut hair short.