The Stratus strain, also known as the ‘Frankenstein’ variant, belongs to the SARS-CoV-2 XFG and XFG.3 lineages and has been spreading swiftly across the United Kingdom, with evidence suggesting it is also circulating globally. According to recent data from the UK Health Security Agency (UKHSA), these variants now account for nearly 30 percent of all COVID-19 cases in England, with XFG.3 emerging as the most dominant strain.In recent weeks, medical experts have voiced concerns that the Stratus variant might have the ability to partially evade immunity built through vaccination, potentially increasing infection risks across all age groups.What Sets the Stratus or ‘Frankenstein’ Variant Apart?One of the unusual symptoms linked to this strain is a hoarse or raspy voice, which doctors say was rarely reported with previous variants. “Unlike earlier strains, Stratus carries specific mutations in its spike protein that may allow it to slip past antibodies formed through prior infection or vaccination,” explained Dr. Kaywaan Khan, a Harley Street general practitioner and founder of the Hannah London Clinic.Is the Stratus Variant More Transmissible?The XFG or Stratus strain is a member of the Omicron family and is a hybrid of two subvariants, LF.7 and LP.8.1.2. This combination of genetic material helps the virus attach more tightly to human cells, making it potentially more contagious. Like other variants, it also contains several mutations that may enhance its ability to evade antibodies produced either through infection or vaccination.Could The ‘Frankenstein’ Variant Be The Most Vaccine-Resistant?Early reports from health authorities suggest that existing COVID-19 vaccines still provide a degree of protection against the Stratus variant. Vaccines designed for earlier strains continue to reduce the risk of severe illness and hospitalization across multiple variants, and experts remain cautiously hopeful that they will do the same against Stratus. However, studies are ongoing to determine how much protection current vaccines actually provide against this specific strain.As the situation develops, public health recommendations may change. Officials are urging people to follow reliable updates and continue to follow safety advice. Vaccination appointments remain widely available in the UK, and eligible individuals are encouraged to receive their doses or boosters as recommended.What Are the Symptoms of Stratus?The most common symptom so far appears to be a sore throat, though overall, the symptoms are similar to those caused by other COVID-19 variants. People infected with Stratus may experience:FeverFatigueCoughSneezingRunny or congested noseNausea, vomiting, or diarrheaSo far, XFG has not been linked to more severe illness compared to previous variants, and hospitalization rates have not shown a sharp increase, which is reassuring.Why The Stratus Variant Still Deserves AttentionAlthough it does not appear to cause more severe disease, the Stratus variant is a reminder that COVID-19 continues to evolve. Vaccines remain the strongest line of defense, and researchers are continuing to study how well they perform against this strain. Staying informed through credible sources and following updated health guidance can help limit the spread and keep communities safer.
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