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On our day to day lives, we fall down, or sometimes get a paper cut, or just a kitchen mishap may happen. Then there it is, a wound. It is such a simple, everyday life thing, but have we ever thought about it? How does it heal? The healing process also has stages, mainly four stages, which includes homeostasis, inflammation, proliferation, and remodeling.
So, what are these, and how does it work?
For the uninitiated, skin is body's largest organ and is a barrier to germs, injury, chemicals, and ultraviolet (UV) light. When the skin is injured, it creates a wound and then your body gets at work immediately to start the healing process.
This is the first stage of the wound healing process. When your skin is injured, the first thing your body does it to create a state of balance and stability by stopping the bleeding. This process is called homeostasis. This is accomplished by tightening the blood vessels, moving platelets to the injury site, as platelet when they aggregate at one place can stop the bleeding. Furthermore, fibrin are formed, which is a form of protein that helps blood clot.
When the fibrin formation is done, a clot develops. This is a very quick process and happens mostly within the first two hours of getting an injury.
This begins once the bleeding is controlled, it starts when inflammatory white blood cells that move towards the wound. These cells clean the wound and also remove the damaged cells and bacteria. This is what creates a scab to cover the injured area.
This stage begins within the very first day of injury and last up to two weeks. It is during this day that you may experience inflammation, swelling, even itching too.
This happens when your skin starts to rebuild it self. This often overlaps with inflammation and during this phase, your body makes new skin tissue and repairs the broken blood vessels that help the new skin tissue to receive nutrients and oxygen.
The skin tissue in this phase is usually a deep red, purple, or even dark brown in color and could have an uneven texture. The process speeds up when the wound is clean and moist.
The last step in the healing process of a wound is remodeling. This is when the wound comes to a close and the cells used for repair are no longer need. So, your body then removes these cells through cellular death also called apoptosis.
This phase starts around three weeks after the injury and could continue for a year or longer, depending on the size of the wound.
You can notice the difference in the way your skin changes. When a wound heals correctly, it looks like a healthy wound, the skin gets darker. Whereas, if your wound is not healing, you may see infection, or a discharge. There might be foul odor or prolonged inflammation too.
There are certain factors which can prolong the healing time, these include:
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Reading non-fiction books is not my cup of tea, while they are informative and important to read, when I read for pleasure, I want to immerse myself in a world that could never be. Reading fiction books like the Harry Potter series, Percy Jackson books and others like the Dragon Rider, were the reason I enjoyed reading. Often using these books as a means to escape difficult feelings, I never even realized how reading these books transformed my mental health, along with my perspective.
Reading plays an important role for your mental health; books offer numerous advantages for one's mental well-being. Whether the preference lies with short stories or lengthy novels, colorful picture books or digital formats, various forms of literature can provide valuable benefits. This piece will explore several key reasons why reading is so beneficial for mental health.
According to a 2022 PLoS One study, reading fiction can improve people's mental well-being. The researchers conducted five different studies to see how various ways of engaging with fiction affect individuals. These methods includes recalling past fiction reading experiences, being instructed to read fiction, discussing fiction in comparison to non-fiction, and discussing different types of fiction.
The research shows that books had a positive influence on people's mood and emotions. However, it appears that simply reading fiction might not lead to an immediate improvement in mental well-being. The brain seems to require a period of processing and understanding the story before positive effects can be observed.
Mental Health First Aid England, a social enterprise that offers guidance and training for mental health in workspaces, explains that whether the preference lies with short stories or lengthy novels, colorful picture books or digital formats, various forms of literature can provide valuable benefits. Here are some ways it helps us.
Reading captivating books brings joy and immersion, making time disappear. Finishing a good story can evoke sadness or eagerness for more, highlighting reading's positive impact.
Engrossing oneself in a book for just six minutes can significantly reduce stress by lowering heart rate and easing tension, outperforming other relaxation methods.
Reading offers an escape from the real world, providing a coping mechanism, especially in childhood. This immersion can be transformative, influencing how we interact with the world.
Reading fiction enhances empathy, improving the ability to understand others' feelings and thoughts, temporarily boosting this crucial social skill.
Lifelong cognitive activities like reading slow down memory loss and reduce mental decline in later life compared to less stimulating pursuits.
Discussing books in reading groups can significantly improve mental health, aiding concentration, emotional understanding, self-awareness, and meaningful discussions.
Discussing books fosters a sense of control and independence, benefiting mental well-being. It provides a positive and safe way to process challenging topics.
Reading for pleasure in adolescence enhances academic performance, social engagement, and personal development, offering insights into adult life.
Research confirms that reading increases intelligence, leading to a larger vocabulary, broader knowledge, and improved verbal skills.
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On the day of World Malaria Day, as we raise awareness on the dangers posed by this mosquito-borne disease, let's delve a bit deeper into how malaria is different from the other mosquito-borne diseases.
Both malaria and dengue are transmitted by female mosquitoes and cause severe illness in humans. There are certain similarities between the two diseases and the mosquito species, which is why the patients and diagnoses are often confused.
As per the co-Principal Investigator, Dr Charles Guissou, for the Target Malaria, a vector control research alliance's Target Malaria Burkina Faso at the Institut de Recherche en Sciences de la Santé, "Dengue and malaria are two very different diseases caused by different pathogens and different mosquito species." “Misdiagnosis between malaria and dengue is common, and this can then contribute to inappropriate medical care.”
Every year, malaria causes 200 million cases worldwide, leading to 600,000 deaths. Many of these cases are from Africa, where children and pregnant women pay the highest price. The World Health Organization (WHO) has also reported that in 2022, Africa was home to 95% of malaria cases and 95% of malaria deaths. The global incidence of dengue has grown significantly in recent decades. Cases reported to WHO increased from 505,430 in 2000 to 6.5 million in 2023.
Dr Ajay Gupta, Head & Director - Internal Medicine, Max Super Speciality Hospital, Vaishali also points out the key differences between malaria and other mosquito-borne diseases. He says, "Malaria is caused by Plasmodium parasites, transmitted through the bite of infected Anopheles mosquitoes. In contrast, dengue, chikungunya, and Zika viruses are transmitted by Aedes mosquitoes. This distinction in the type of mosquito also reflects differences in peak biting times—Anopheles mosquitoes bite during nighttime, while Aedes mosquitoes are daytime biters."
"Another key difference lies in complications and disease progression. Malaria, especially caused by Plasmodium falciparum, can progress rapidly to severe illness with cerebral involvement, anemia, kidney failure, and even death if not promptly treated. Dengue, on the other hand, is known for a sudden drop in platelet count and risk of hemorrhage. Chikungunya commonly leads to prolonged joint pain, sometimes lasting weeks or even months after the infection clears," notes the doctor.
There is also a difference between how the mosquitoes that spread dengue and malaria.
It is responsible for spreading dengue and has white stripes down the center of the thorax. It also has a resting position where its body is kept low and parallel to the ground, with the proboscis angled downward. It is slender, and the wings have distinctive white markings.
It is responsible for causing malaria and has long palps. It is dark in color and the resting position follows it abdomen at a 45-degree angle to the surface.
Zika is a viral infection also transmitted by Aedes mosquitoes, which is the first difference from malaria, in the species of mosquito that causes it. As per the WHO, those with Zika virus do not tend to experience symptoms, and if they do, it includes rash, fever, conjunctivitis, and muscle and joint pain. The symptoms are also what makes it different. They appear from 3 to 14 days after being bitten.
This is also caused by Aedes mosquitoes, and the symptoms usually appear within 4 to 8 days after infection. The symptoms include fever, joint pain, headaches, and nausea.
This is caused by Aedes and haemagogus mosquitoes. People who are infected with this virus do not get sick and experience only mild symptoms. As per the Centers for Disease Control and Prevention (CDC), 12% of people who have symptoms develop serious illness, which includes organ failure and jaundice.
The key difference between all other mosquito-borne diseases and malaria is the species of the mosquito that causes it. While all the others are caused by Aedes, malaria is caused by the Anopheles.
According to the scientists at the University of Emory, in their 2010 study, they found that beer produces an odour in your body that is irresistible to the malaria-carrying mosquitoes.
There are rare strains of this disease which could in fact take months or even years to get diagnosed. In one of the rare cases, malaria was diagnosed four years later the individuals were infected, reported UK's The Telegraph.
In 1943, Disney was tasked with creating a film to promote public health awareness. The result? The Winged Scourge — a rather unusual PSA where the Seven Dwarfs learn how to fight off malaria-spreading mosquitoes.
George Washington battled malaria, and the disease is also believed to have claimed the lives of Pope Leo and Pope Sixtus—just a few of its prominent victims.
The doctor also points out that diagnosis and treatment also vary. "Malaria is typically confirmed with a blood smear or rapid diagnostic test and is treated with specific antimalarial drugs. There is no antiviral treatment for dengue, chikungunya, or Zika—management is primarily supportive," he says.
In India, we often see a spike in these illnesses during and after the monsoon season, However, malaria control efforts—such as early diagnosis, insecticide-treated bed nets, and vector control—have significantly reduced the burden in recent years.
"Preventive strategies like eliminating stagnant water, using mosquito repellents, and ensuring proper sanitation are universally effective. But recognizing the distinct nature of malaria is key to prompt diagnosis and management," notes Dr Gupta.
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In 2022, about 1 in 5, which is around 702,880, people died due to cardiovascular diseases (CVD) in the United States. There are many factors around you that affect your heart health. Things like what food you eat, whether the area you live in is polluted or not and also what kind of lifestyle you lead. There are many risk factors for heart diseases like high blood pressure, high cholesterol levels or smoking, which are key risk factors according to the Centers of Disease Control and Prevention (CDC). The CDC explains about 47% of US citizens have at least one of these three risk factors.
Another risk factor could be the place you live in. A new study published in the European Society of Cardiology April 2025 revealed that the walkability of a neighborhood can play a big role for your cardiovascular health. The study revealed that individuals living in areas with low walkability had a 5% higher risk of developing CVD compared to those in very walkable neighborhoods. Interestingly, even in neighborhoods that improved in walkability over time, the risk of CVD remained about 5% higher for those who started in low-walkability areas, possibly due to the lasting effects of earlier sedentary habits.
To figure out how walkable a neighborhood is, the researchers in the study looked at several things. They checked how many people lived in the area (population density), how many shops were nearby, if there were parks and green spaces, and if there were sidewalks to walk on. They also considered if different types of buildings were mixed together (like shops and homes), if there was good public transportation, and how well the streets connected to each other. All these things together helped them decide how easy it was to walk around in a certain neighborhood.
Researchers studied over three million adults who were at least 40 years old and didn't have any heart problems when the study started. The researchers kept track of how walkable each person's neighborhood was for 13 years. They also checked if the walkability of these neighborhoods stayed the same, got better, or got worse during that time.
The findings of this study support what doctors have known for a long time: moving your body is good for your health, especially your heart. What's interesting is that you don't need to do intense workouts to see the benefits. Even small amounts of activity, like walking your dog in a park or carrying your groceries home from the store, can make a difference. These little bursts of energy throughout the day can add up and help lower your risk of getting heart disease.
A report from 2023 from Smart Growth America found that less than 7% of people in America actually live in very walkable urban neighborhoods. Interestingly, studies have shown that minority groups often live in more walkable neighborhoods. However, these same groups are also more likely to suffer from heart and blood sugar problems. This might be because even in walkable areas, factors like safety, clean environments, and good sidewalks and parks might not be available in all neighborhoods.
Even if you don't live in a very walkable area, there are still things you can do to move more. You might need to get a little creative! You can try lifting weights or doing yoga while you watch TV. If you drive to the store, park a little further away so you have to walk more. Take the stairs instead of the elevator. Stand up and move around when you're on the phone, have walking meetings if possible, and make sure to get up and stretch every hour.
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