Health and Me

Ishita Roy

Hundreds Report Pancreatitis After Using Weight-Loss Drugs; UK Launches A Study To Investigate

After many people reported problems with their pancreas post taking <span>weight loss</span> and diabetes injections, the UK health officials launched a study to look into side-effects of these drugs. 

Cases of <span>pancreatitis</span>, which causes inflammation of the pancreas, which is a gland located behind the stomach, has been fatal. These cases have been linked to GLP-1 medicines, also the glucagon-like peptide-1 receptor agonists. 

The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) is investigating a rise in reports of acute pancreatitis potentially linked to GLP-1 weight-loss medications. This follows an increase in submissions to the MHRA’s Yellow Card scheme, which tracks adverse reactions to medicines and medical devices.

<h4>What Happens In Acute Pancreatitis?</h4>

Acute pancreatitis is a sudden inflammation of the pancreas, a digestive gland behind the stomach, and often requires hospitalisation. Symptoms include intense abdominal pain, nausea, and fever. GLP-1 drugs, such as Mounjaro (tirzepatide), <span>Wegovy</span> and <span>Ozempic</span> (semaglutide), and liraglutide, list pancreatitis as an “uncommon” side effect—estimated to affect up to one in 100 users.

To date, nearly 400 cases of acute pancreatitis have been reported in relation to these drugs, with 181 linked to Mounjaro. Alarmingly, over a quarter of those reports have emerged in 2025 alone. This year, the Yellow Card scheme has recorded 101 cases related to tirzepatide and 22 tied to semaglutide.

An MHRA spokesperson noted: “With increased usage, we’re seeing more Yellow Card reports involving GLP-1 medicines and acute pancreatitis.” While there’s currently no known genetic link, the MHRA is exploring whether genetics might influence susceptibility to such side effects. It has called on both patients and healthcare professionals to report suspected drug-related pancreatitis.

<h4>The Study: Who Can Be Part Of It?</h4>

Those affected may be invited to join the Yellow Card Biobank study, conducted with Genomics England. Participants will provide health information and saliva samples to help researchers investigate genetic factors that may affect drug reactions.

Dr Alison Cave, MHRA’s chief safety officer, said nearly a third of all medicine side effects could be preventable with genetic testing, which may also help reduce the estimated £2.2 billion annual cost of adverse drug reactions to the NHS.

Drug manufacturers have responded to the concerns. Eli Lilly, which makes Mounjaro, stated that patient safety remains a top priority and noted that pancreatitis is already listed as a known side effect. Novo Nordisk UK, maker of Ozempic and Wegovy, also stressed the importance of using GLP-1 medications only under medical supervision, while continuing to monitor safety data closely.

The MHRA’s ongoing investigation aims to improve understanding of these side effects as GLP-1 medications become more widely used for managing obesity and diabetes.

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After many people reported problems with their pancreas post taking weight loss and diabetes injections, the UK health officials launched a study to look into side-effects of these drugs. Cases of pancreatitis, which causes inflammation of the pancreas, which is a gland located behind the stomach, has been fatal. These cases have been linked to GLP-1 medicines, also the glucagon-like peptide-1 receptor agonists. The Background The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) is investigating a rise in reports of acute pancreatitis potentially linked to GLP-1 weight-loss medications. This follows an increase in submissions to the MHRA’s Yellow Card scheme, which tracks adverse reactions to medicines and medical devices.What Happens In Acute Pancreatitis?Acute pancreatitis is a sudden inflammation of the pancreas, a digestive gland behind the stomach, and often requires hospitalisation. Symptoms include intense abdominal pain, nausea, and fever. GLP-1 drugs, such as Mounjaro (tirzepatide), Wegovy and Ozempic (semaglutide), and liraglutide, list pancreatitis as an “uncommon” side effect—estimated to affect up to one in 100 users.To date, nearly 400 cases of acute pancreatitis have been reported in relation to these drugs, with 181 linked to Mounjaro. Alarmingly, over a quarter of those reports have emerged in 2025 alone. This year, the Yellow Card scheme has recorded 101 cases related to tirzepatide and 22 tied to semaglutide.What Did The Authorities Say?An MHRA spokesperson noted: “With increased usage, we’re seeing more Yellow Card reports involving GLP-1 medicines and acute pancreatitis.” While there’s currently no known genetic link, the MHRA is exploring whether genetics might influence susceptibility to such side effects. It has called on both patients and healthcare professionals to report suspected drug-related pancreatitis.The Study: Who Can Be Part Of It?Those affected may be invited to join the Yellow Card Biobank study, conducted with Genomics England. Participants will provide health information and saliva samples to help researchers investigate genetic factors that may affect drug reactions.Dr Alison Cave, MHRA’s chief safety officer, said nearly a third of all medicine side effects could be preventable with genetic testing, which may also help reduce the estimated £2.2 billion annual cost of adverse drug reactions to the NHS.Drug manufacturers have responded to the concerns. Eli Lilly, which makes Mounjaro, stated that patient safety remains a top priority and noted that pancreatitis is already listed as a known side effect. Novo Nordisk UK, maker of Ozempic and Wegovy, also stressed the importance of using GLP-1 medications only under medical supervision, while continuing to monitor safety data closely.The MHRA’s ongoing investigation aims to improve understanding of these side effects as GLP-1 medications become more widely used for managing obesity and diabetes.

hundreds report pancreatitis after using weight-loss drugs; uk launches a study to investigate

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<span>Skin cancer</span> is much more common than people think it is. It is a disease where <span>cancer</span> cells form in the tissue of the skin. The National Cancer Institute explains that there are different types of skin cancer. While it is treatable, any cancer diagnosis comes with the understanding that your chances of survival are declining. A big reason why it is so treatable is because of early diagnosis. This particular symptom of skin cancer becomes much more apparent with just 15 minutes in the sun. 

As many enjoy the recent sunny weather, it's crucial to be aware of the risks of sun exposure. Cancer UK is urging everyone to monitor their skin for signs of skin cancer, which can develop after as little as 15 minutes in the sun. Even with sunscreen, you can still get burned if the SPF isn't high enough or if it's not reapplied regularly. 

<h2>Link Between <span rel="noindex">Sunburn and Cancer Risk</span> </h2>

Getting a sunburn is a clear indication of skin damage caused by too much UV radiation, which harms the DNA in your skin cells. While one sunburn doesn't guarantee skin cancer, the more often you get burned, the higher your risk. To protect yourself, remember to: 

Stay in the shade, especially between 11 AM and 3 PM, when the sun's rays are strongest. This greatly lowers your exposure to harmful UV radiation, making it safer to be outside during these peak hours. 

Wear loose clothing, a wide-brimmed hat, and UV-protective sunglasses. These items create a barrier, shielding your skin and eyes from direct sunlight and reducing your overall sun exposure. 

Use sunscreen with at least SPF30 and 4 or 5 stars, and put on plenty of it, often. Regular and correct sunscreen use creates a protective layer, significantly lowering your risk of sunburn and long-term skin damage from UV rays. 

<h2>Spotting the Early Warning Signs </h2>

Non-melanoma skin cancer often shows up on skin exposed to the sun. To catch it early, it helps to know how your skin normally looks so you can spot any changes. Regular self-checks are key for early detection. Here's how to check your skin: 

Use a handheld mirror for hard-to-see areas, or ask a friend or partner for help. This ensures you don't miss any suspicious spots on your back or other less visible parts of your body. 

Take photos of anything that seems unusual. Include a ruler or tape measure in the photo to track its size and changes. These pictures are important for your doctor to assess any evolving skin concerns. They might look like:

<ul><li>A new spot or sore that doesn't heal within a few weeks. Persistent, non-healing lesions are a significant warning sign that warrant immediate medical attention to rule out cancerous growth. </li><li></li><li>A new lump that is firm, growing, or has an unusual color. Any new, unexplained lump on your skin should be promptly evaluated by a healthcare professional, especially if it changes in appearance. </li><li></li><li>A red or dark patch that might be scaly or crusty. Discolored patches, particularly those with rough textures or irregular borders, can be indicators of skin cancer and require medical assessment. </li><li></li><li>Something that is itchy, crusty, or bleeding without obvious injury. These symptoms, especially when persistent, suggest that a skin lesion might be abnormal and necessitate a doctor's examination for proper diagnosis.</li></ul>

Sign Of Skin Cancer

early Sign Of Skin Cancer

Sunburn and Cancer Risk

Cancer

Skin Cancer

how to identify skin cancer

Skin cancer is much more common than people think it is. It is a disease where cancer cells form in the tissue of the skin. The National Cancer Institute explains that there are different types of skin cancer. While it is treatable, any cancer diagnosis comes with the understanding that your chances of survival are declining. A big reason why it is so treatable is because of early diagnosis. This particular symptom of skin cancer becomes much more apparent with just 15 minutes in the sun. As many enjoy the recent sunny weather, it's crucial to be aware of the risks of sun exposure. Cancer UK is urging everyone to monitor their skin for signs of skin cancer, which can develop after as little as 15 minutes in the sun. Even with sunscreen, you can still get burned if the SPF isn't high enough or if it's not reapplied regularly. Link Between Sunburn and Cancer Risk Getting a sunburn is a clear indication of skin damage caused by too much UV radiation, which harms the DNA in your skin cells. While one sunburn doesn't guarantee skin cancer, the more often you get burned, the higher your risk. To protect yourself, remember to: Seek shade Stay in the shade, especially between 11 AM and 3 PM, when the sun's rays are strongest. This greatly lowers your exposure to harmful UV radiation, making it safer to be outside during these peak hours. Cover up with loose clothing Wear loose clothing, a wide-brimmed hat, and UV-protective sunglasses. These items create a barrier, shielding your skin and eyes from direct sunlight and reducing your overall sun exposure. Apply sunscreen Use sunscreen with at least SPF30 and 4 or 5 stars, and put on plenty of it, often. Regular and correct sunscreen use creates a protective layer, significantly lowering your risk of sunburn and long-term skin damage from UV rays. Spotting the Early Warning Signs Non-melanoma skin cancer often shows up on skin exposed to the sun. To catch it early, it helps to know how your skin normally looks so you can spot any changes. Regular self-checks are key for early detection. Here's how to check your skin: Use a handheld mirror for hard-to-see areas, or ask a friend or partner for help. This ensures you don't miss any suspicious spots on your back or other less visible parts of your body. Take photos of anything that seems unusual. Include a ruler or tape measure in the photo to track its size and changes. These pictures are important for your doctor to assess any evolving skin concerns. They might look like:A new spot or sore that doesn't heal within a few weeks. Persistent, non-healing lesions are a significant warning sign that warrant immediate medical attention to rule out cancerous growth. A new lump that is firm, growing, or has an unusual color. Any new, unexplained lump on your skin should be promptly evaluated by a healthcare professional, especially if it changes in appearance. A red or dark patch that might be scaly or crusty. Discolored patches, particularly those with rough textures or irregular borders, can be indicators of skin cancer and require medical assessment. Something that is itchy, crusty, or bleeding without obvious injury. These symptoms, especially when persistent, suggest that a skin lesion might be abnormal and necessitate a doctor's examination for proper diagnosis.

15 minutes in the sun can reveal this sign of skin cancer

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The <span>teen birth rate</span> in the U.S. continued its steady decline in 2022, dropping by 2% from the previous year, as per the latest final report from the Centers for Disease Control and Prevention (CDC).

In 2022, there were 13.6 births per 1,000 females aged 15 to 19, down from 13.9 in 2021. This amounts to nearly 3,200 fewer births in that age group compared to the year before.

The rate has reached a new record low each year since 2009. Overall, it has declined by 67% since 2007 and 78% since 1991 — a trend the CDC attributes to reduced sexual activity among teens and increased use of contraception by those who are sexually active.

The annual drop also witnessed a 3% rate decline to 25.8 per 1,000 among women 18 to 19 years old. The rate among girls 15 to 17 years old in 2022 remained unchanged from the last year at 5.6 per 1,000. 

In 2022, teen birth rates declined across several racial and ethnic groups. The rates dropped by 7% among both Black and American Indian and Alaska Native (AIAN) females, and by 3% among white females, reaching 9.1 births per 1,000. Rates remained largely unchanged for Asian teens as well as Native Hawaiians and other Pacific Islanders (NHOPI), while Hispanic teens saw a slight 1% increase. The highest birth rates were recorded among AIAN (22.5 per 1,000), NHOPI (20.5), and Black (20.3) females.

2022 also witnessed a decline in birth rate in 13 states in 2022. It has ranged from a 3% drop in Florida, to a 12% drop in Oklahoma. However, it essentially remained unchanged in 37 states and the District of Columbia. Overall, the teen birth rates among the states have ranged from a low of 4.6 births per 1,000 to a high of 26.4 per 1,000.

Here's a list of top 10 states with the highest teen birth rates in 2022

The teen birth rate here was recorded at 19.7 per 1,000

The teen birth rate here was recorded at 19.8 per 1,000

The teen birth rate here was recorded at 20.4 per 1,000

The teen birth rate here was recorded at 20.9 per 1,000

The teen birth rate here was recorded at 21 per 1,000

The teen birth rate here was recorded at 21.2 per 1,000

The teen birth rate here was recorded at 21.8 per 1,000

The teen birth rate here was recorded at 23.7 per 1,000

The teen birth rate here was recorded at 24.6 per 1,000

The teen birth rate here was recorded at 26.4 per 1,000

Having a high teen birth rate means the number of teen pregnancy is also high. As per the World Health Organization (WHO), adolescent pregnancies are those between the age of 15 to 19, also known as <span>teen pregnancies</span>. WHO notes that adolescent mothers (aged 10–19 years) face higher risks of eclampsia, puerperal endometritis and systemic infections than women aged 20–24 years, and babies of adolescent mothers face higher risks of low birth weight, preterm birth and severe neonatal condition.

As per a 2022 report presented at the Seminars in Reproductive Medicine, titled, Complications of Pregnancy in Adolescents, teen pregnant mothers are at increase risks of poor obstetric outcomes including preterm delivery, low birth weight, eclampsia, postpartum hemorrhage, anemia, and infant, as well as maternal morbidity.

health news US

birth rates US

US birth rates

teen pregnancies

teen birth rate

The teen birth rate in the U.S. continued its steady decline in 2022, dropping by 2% from the previous year, as per the latest final report from the Centers for Disease Control and Prevention (CDC).In 2022, there were 13.6 births per 1,000 females aged 15 to 19, down from 13.9 in 2021. This amounts to nearly 3,200 fewer births in that age group compared to the year before.The rate has reached a new record low each year since 2009. Overall, it has declined by 67% since 2007 and 78% since 1991 — a trend the CDC attributes to reduced sexual activity among teens and increased use of contraception by those who are sexually active.The annual drop also witnessed a 3% rate decline to 25.8 per 1,000 among women 18 to 19 years old. The rate among girls 15 to 17 years old in 2022 remained unchanged from the last year at 5.6 per 1,000. In 2022, teen birth rates declined across several racial and ethnic groups. The rates dropped by 7% among both Black and American Indian and Alaska Native (AIAN) females, and by 3% among white females, reaching 9.1 births per 1,000. Rates remained largely unchanged for Asian teens as well as Native Hawaiians and other Pacific Islanders (NHOPI), while Hispanic teens saw a slight 1% increase. The highest birth rates were recorded among AIAN (22.5 per 1,000), NHOPI (20.5), and Black (20.3) females.2022 also witnessed a decline in birth rate in 13 states in 2022. It has ranged from a 3% drop in Florida, to a 12% drop in Oklahoma. However, it essentially remained unchanged in 37 states and the District of Columbia. Overall, the teen birth rates among the states have ranged from a low of 4.6 births per 1,000 to a high of 26.4 per 1,000.Here's a list of top 10 states with the highest teen birth rates in 202210. New MexicoThe teen birth rate here was recorded at 19.7 per 1,0009. West VirginiaThe teen birth rate here was recorded at 19.8 per 1,0008. TexasThe teen birth rate here was recorded at 20.4 per 1,0007. AlabamaThe teen birth rate here was recorded at 20.9 per 1,0006. TennesseeThe teen birth rate here was recorded at 21 per 1,0005. OklahomaThe teen birth rate here was recorded at 21.2 per 1,0004. Kentucky The teen birth rate here was recorded at 21.8 per 1,0003. LouisianaThe teen birth rate here was recorded at 23.7 per 1,0002. ArkansasThe teen birth rate here was recorded at 24.6 per 1,0001. MississippiThe teen birth rate here was recorded at 26.4 per 1,000Why Is This Concerning?Having a high teen birth rate means the number of teen pregnancy is also high. As per the World Health Organization (WHO), adolescent pregnancies are those between the age of 15 to 19, also known as teen pregnancies. WHO notes that adolescent mothers (aged 10–19 years) face higher risks of eclampsia, puerperal endometritis and systemic infections than women aged 20–24 years, and babies of adolescent mothers face higher risks of low birth weight, preterm birth and severe neonatal condition.As per a 2022 report presented at the Seminars in Reproductive Medicine, titled, Complications of Pregnancy in Adolescents, teen pregnant mothers are at increase risks of poor obstetric outcomes including preterm delivery, low birth weight, eclampsia, postpartum hemorrhage, anemia, and infant, as well as maternal morbidity.

10 us states with the highest teen birth rates

Relying On Fitness Trackers For Accuracy May Not Be The Right Move For People With Obesity: Study

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Not Wegovy or Mounjaro Or Ozempic: This New Monthly Weight Loss Jab Helped People Drop 20% Body Fat

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Fitness trackers have become quite popular in recent years. Having a device that can give you accurate stats about your heart rate, distance traveled, as well as how many calories you may have burnt can be a great tool for health. These stats help people devise their own fitness routines and according to the data they get. However, are these stats reliable? 

A new study says that fitness trackers aren't good at measuring how active people with obesity really are. This is because people with extra weight walk differently, have different speeds, and burn energy in unique ways. This means their fitness devices don't give them correct readings, according to researchers writing in Scientific Reports.

<h2>Why Current Trackers Miss the Mark </h2>

Most fitness trackers are designed for people who don't have obesity. Because of this, they don't give accurate information to those who do. For example, trackers worn on the hip often give wrong energy burn readings because people with obesity have a different way of walking and might wear the device at an angle. While wrist-worn trackers are generally better, they haven't been properly tested and set up for people with obesity. 

The research team has now created a new calculation that allows smartwatches to more precisely track calories burned by people with obesity. Tests in a lab setting show this new method is over 95% accurate in real-world situations. 

Without a reliable way to measure activity from wrist devices, it's hard to know exactly how active people with obesity are each day. This makes it difficult to create personalized health programs and improve their health.

<h2>Testing and Open-Source Availability </h2>

The team put their new algorithm through rigorous testing, comparing it against multiple other advanced methods for estimating exertion. They used research-grade fitness trackers and wearable cameras to precisely identify moments when wrist sensors misjudged calorie burn. 

In one part of the study, participants wore a fitness tracker and a special mask that measured energy burn by tracking the oxygen they breathed in and the carbon dioxide they breathed out. In another part, participants wore a fitness tracker and a body camera during their daily routines. 

The research also involved having people do standard exercises that were adjusted for their weight, like wall push-ups instead of floor push-ups. This showed that current "standard" workouts often exclude many people, and it's important to rethink how success is measured in fitness so that everyone's hard work is recognized. 

The next step is to release an activity-monitoring app for Apple and Android smartwatches that will use this new calculation. Importantly, this calculation is open source, meaning other researchers can freely use it and build upon it. The team noted that, to their knowledge, no other similar open-source calculation has been made available for commercial wrist-worn devices. 

<h2>Some Other Ways Fitness Trackers Can Aid Your Health </h2>

While the calories count may not be as accurate as we hope, there are many other ways fitness trackers can aid our health. The Brown Health University explains that these fitness trackers can 

Many fitness trackers can monitor your pulse and heart rate during exercise. This allows you to target specific heart rate zones, helping you get the most out of your workouts. Trackers are also a great way to ensure you hit that recommended 30 minutes of daily activity. 

If you're aiming for better sleep, a fitness tracker can be a useful tool. While it can't replace a full medical sleep study, a tracker with sleep monitoring uses sensors to detect your heart rate and its variations, which helps determine if you're asleep or awake.

Your wearable fitness tracker can easily connect with a variety of other health-related apps on your smartphone. This makes it simple to keep track of your progress on the go. You can check off daily habits, log your water intake, or record your workouts—all from your wrist. 

Fitness tracker accuracy

how accurate are smartwatches

Fitness trackers for health

are fitness trackers useful for obese people

how accurate are trackers for obese people

do fitness trackers work on obese people

Fitness trackers have become quite popular in recent years. Having a device that can give you accurate stats about your heart rate, distance traveled, as well as how many calories you may have burnt can be a great tool for health. These stats help people devise their own fitness routines and according to the data they get. However, are these stats reliable? A new study says that fitness trackers aren't good at measuring how active people with obesity really are. This is because people with extra weight walk differently, have different speeds, and burn energy in unique ways. This means their fitness devices don't give them correct readings, according to researchers writing in Scientific Reports. Why Current Trackers Miss the Mark Most fitness trackers are designed for people who don't have obesity. Because of this, they don't give accurate information to those who do. For example, trackers worn on the hip often give wrong energy burn readings because people with obesity have a different way of walking and might wear the device at an angle. While wrist-worn trackers are generally better, they haven't been properly tested and set up for people with obesity. A New, More Accurate Solution The research team has now created a new calculation that allows smartwatches to more precisely track calories burned by people with obesity. Tests in a lab setting show this new method is over 95% accurate in real-world situations. Without a reliable way to measure activity from wrist devices, it's hard to know exactly how active people with obesity are each day. This makes it difficult to create personalized health programs and improve their health. Testing and Open-Source Availability The team put their new algorithm through rigorous testing, comparing it against multiple other advanced methods for estimating exertion. They used research-grade fitness trackers and wearable cameras to precisely identify moments when wrist sensors misjudged calorie burn. In one part of the study, participants wore a fitness tracker and a special mask that measured energy burn by tracking the oxygen they breathed in and the carbon dioxide they breathed out. In another part, participants wore a fitness tracker and a body camera during their daily routines. The research also involved having people do standard exercises that were adjusted for their weight, like wall push-ups instead of floor push-ups. This showed that current "standard" workouts often exclude many people, and it's important to rethink how success is measured in fitness so that everyone's hard work is recognized. The next step is to release an activity-monitoring app for Apple and Android smartwatches that will use this new calculation. Importantly, this calculation is open source, meaning other researchers can freely use it and build upon it. The team noted that, to their knowledge, no other similar open-source calculation has been made available for commercial wrist-worn devices. Some Other Ways Fitness Trackers Can Aid Your Health While the calories count may not be as accurate as we hope, there are many other ways fitness trackers can aid our health. The Brown Health University explains that these fitness trackers can Monitor your Heart Health Many fitness trackers can monitor your pulse and heart rate during exercise. This allows you to target specific heart rate zones, helping you get the most out of your workouts. Trackers are also a great way to ensure you hit that recommended 30 minutes of daily activity. Track Your Sleep If you're aiming for better sleep, a fitness tracker can be a useful tool. While it can't replace a full medical sleep study, a tracker with sleep monitoring uses sensors to detect your heart rate and its variations, which helps determine if you're asleep or awake. Connect with Other Health Apps Your wearable fitness tracker can easily connect with a variety of other health-related apps on your smartphone. This makes it simple to keep track of your progress on the go. You can check off daily habits, log your water intake, or record your workouts—all from your wrist.  

relying on fitness trackers for accuracy may not be the right move for people with obesity: study

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Hundreds Report Pancreatitis After Using Weight-Loss Drugs; UK Launches A Study To Investigate

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15 Minutes In The Sun Can Reveal This Sign Of Skin Cancer

10 US States With The Highest Teen Birth Rates

Relying On Fitness Trackers For Accuracy May Not Be The Right Move For People With Obesity: Study

Health Conditions A-Z

15 Minutes In The Sun Can Reveal This Sign Of Skin Cancer

Commonwealth Swimmer Archie Goodburn And His Journey With A Rare Cancer That Kills Before 40

10 US States With The Highest Teen Birth Rates