Menopause marks the end of a woman’s reproductive years. Although many people believe that stopping mensuration is the only aspect of menopause, women experience hot flashes, night sweats, emotional changes, difficulty sleeping and much more. A new study suggests that some women who experience premature menopause face a higher risk of depression. Premature menopause occurs when a woman's ovaries stop working normally before she turns 40. Past research have already shown that premature menopause can more than triple a woman's risk of depression and nearly quintuple her risk of anxiety. However, these new findings, published recently in the journal Menopause, reveal that there are certain factors make some women with this condition even more vulnerable to depression than others. Who is at Higher Risk for Depression? The study identified several factors that increase a woman's risk for depression if she goes through premature menopause: Earlier Onset Women who began premature menopause at a younger age showed a higher likelihood of experiencing depression. The earlier the body entered this change, the greater the emotional challenge appeared to be for them. Genetic Cause If premature menopause happened due to inherited genes, a woman's risk of depression increased significantly. This underlying biological factor seems to contribute to greater vulnerability for mental health struggles. Worse Menopause Symptoms Women who suffered from more intense and bothersome overall menopause symptoms were more susceptible to developing depression. The severity of physical discomfort often mirrored increased emotional distress. Grief and Lack of Support Women coping with the profound sadness of losing their ability to have children, or those without strong emotional backing from others, faced a greater chance of experiencing depression. Support systems are vital here. Interestingly, the study found that using hormone therapy did not affect a woman's depression risk, even if it helped ease some other menopause symptoms. This suggests that psychological and social factors are very important in this context. Experts believe that mental health support for these women should focus on these aspects to address their unique needs. While severe menopause symptoms generally increased depression risk, hot flashes, a commonly bothersome symptom, were not specifically linked to depression in this study. The Importance of Screening Around 3 out of every 100 women experience premature menopause. In this study, researchers looked at data from nearly 350 women with premature menopause, and about 30% of them showed symptoms of depression. Because of the high number of women with depressive symptoms in this group, it's important to regularly screen these vulnerable women for depression. It's also worth noting that while hormone therapy is standard care for managing some menopause symptoms and for preventive health in premature menopause, it's not the primary treatment for mood disorders. This study's results, showing no difference in depressive symptoms between those using hormones and those who weren't, support this point. Looking Ahead: Future Research The researchers emphasized that future studies are needed to further explore these connections, as this study wasn't designed to prove a direct cause-and-effect link between premature menopause and depression. These future studies could also help determine the most effective ways to help women avoid depression when they go through premature menopause.