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New advice from the NHS suggests that people who stop taking weight-loss drugs like Wegovy and Mounjaro should have check-ups for at least a year. The main reason for this is that it's very common for people to gain most of the weight once they stop the medication.
The guidance from NICE (National Institute for Health and Care Excellence) emphasizes that managing weight is a long-term effort, not a quick fix. Patients need extra help and a clear plan to maintain their new weight, which includes habits like eating healthy food and being physically active.
Clinical trials show that people on these drugs often regain a lot of the weight they lost. For example, a trial for Wegovy found that patients put back on about two-thirds of their lost weight after they stopped the injections. It was a similar story for those who took Mounjaro.
Professor Jonathan Benger from NICE explained that the time right after stopping treatment is very important. He said people need "structured support" to keep up the healthy changes they've made. The new advice encourages patients to create healthy habits, use tools to monitor their own weight, and get support from family, friends, and online groups.
Obesity affects about one in four adults in England. While an estimated 1.5 million people in the UK are using these weight-loss jabs, most are paying for them privately and won't get this NHS support.
Wegovy is available on the NHS for a period of two years for those who have health problems because of their weight and have a high BMI. The drug Mounjaro is expected to be offered to about 240,000 people over the next three years, and there's no set time limit for how long they can take it.
Both drugs work by reducing a person's appetite. They are given along with programs that help people make healthy changes to their diet and exercise habits.
Does Mounjaro Work For Everyone?
The UC Health explains that currently Mounjaro is approved for people with diabetes, not for those who are overweight or obese without diabetes. There is still a lot we have to learn about Mounjaro and researchers are working on the same. A big question that everyone who wishes to start on the weight loss drug are thinking about is whether you will have to keep using the drug forever or can you stop.
To maintain the weight loss achieved with Mounjaro, you will likely need to keep taking the medication indefinitely.
If you lose a significant amount of weight with Mounjaro, Wegovy, or Ozempic, you will likely need to continue taking the medication to keep the weight off. People who have stopped taking Ozempic and Wegovy have typically regained the weight they lost.
As one UC Health expert noted that if you stop taking these medications, and don’t change your behaviors, then the weight can pile back on. Since Mounjaro is newer, there is less information about long-term use, but the trend is expected to be similar.
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Headaches may not be that serious, but they have the ability to derail your day within minutes. Throughout the day, lack of sleep or food or any other ailments like fever can lead to a throbbing headaches. However, women complain about headaches more often than men, why is that?
Headaches can seriously impact your life, and in the U.S. alone, they lead to 112 million sick days each year, according to Johns Hopkins Medicine.
While about a third of all people get headaches, women suffer from them far more often than men. One of the main reasons for this difference could be hormonal changes.
Hormone fluctuations can trigger headaches. Specifically, changes in estrogen levels can cause problems. Estrogen is a key hormone in the female reproductive system, and headaches can happen anytime its levels shift. This includes dips in estrogen right before your menstrual cycle, as well as during the start of menopause or after a hysterectomy. Headache triggers related to hormones include:
The two most common types of headaches for women are tension headaches and migraines. A tension headache often feels like a tight band squeezing your head. A migraine, however, is typically a throbbing or pounding headache. Migraine symptoms often include:
For every man who gets a migraine, three women suffer from the same severe headaches, which can come with nausea and sensitivity to light and sound. This makes migraines one of the most common disabling conditions for women globally. Researchers at UCLA believe they may have found a reason for this 3-to-1 ratio: women might have a quicker trigger for the brain activity that causes migraines.
A team of researchers studied mice and discovered a big difference between males and females in a process called cortical spreading depression (CSD). CSD is a powerful wave of brain activity that scientists believe is the main cause of migraines. This wave can cause not only the headache pain, but also the vision problems, nausea, and dizziness that often go with them.
In their tests, the female mice were much easier to trigger. The brain waves that lead to migraines started with a weaker signal in females compared to males. In fact, it took a signal up to three times stronger to start CSD in the male mice.
Making some changes to your daily life can help you manage migraines and headaches. It's important to avoid known triggers like alcohol and stress. Staying hydrated is also key—aim for 1.5 to 2 liters of water each day. If caffeine affects your sleep, limit coffee and energy drinks. Finally, make sure you get enough quality sleep and maintain a consistent sleep schedule and meal times.
Other treatments that can help include physical therapy for muscle stiffness in your neck and shoulders, and behavioral therapy to help reduce stress. If these lifestyle changes don't work, you should talk to your doctor. By understanding how your hormones can cause headaches, you can find the right treatment to manage your symptoms and get back to your daily routine.
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Often, caught up in the worries of paying your bills and other stress, we forget to prioritize our health. How often have you ignored a cough or forgotten to take your vitamins for the day? Although bad things and surprising issues do pop up, we don’t consider them an issue until it affects us. It was the same for this young flight attendant, who never knew that a simple cough could lead to a shocking diagnosis, possibly saving his life.
In 2021, Warren developed a cough that came and went. With the COVID-19 pandemic ongoing, he was regularly tested for his job, with all results coming back negative. When the cough persisted, he visited his doctor, who initially prescribed antihistamines and then omeprazole, suspecting acid reflux.
Wanting more answers, Warren had a chest X-ray and a CT scan. The scans eventually revealed an abnormality in one of his lungs, leading to surgery in February 2022. It was then that he received the devastating diagnosis of Stage 3a lung cancer, which had spread to two of his lymph nodes.
Warren's surgery was followed by several cycles of chemotherapy. He experienced severe side effects, including hair loss, constant fatigue, and sickness. After completing his treatment, Warren was signed off as fit to fly in January 2023, following a series of clear scans. He has since returned to work on long-haul flights and is enjoying running again, logging 15-20 miles a week.
Despite his recovery, Warren is candid about the ongoing mental health challenges. He plans to start counseling to manage his anxiety about the cancer returning and is committed to fundraising for organizations like Cancer Research UK and the Roy Castle Lung Cancer Foundation.
Being the leading cause of cancer-related deaths, lung cancer has the highest mortality rates in both men and women, according to the World Health Organization. What’s even more concerning is that it is often diagnosed in the advanced stage, during which the treatment options available are limited.
Warren's story highlights that lung cancer can affect anyone, regardless of age or lifestyle. He urges people to listen to their bodies and see a doctor if something doesn't feel right.
Early-stage lung cancer often has no obvious symptoms. However, you should be aware of a persistent cough that doesn't go away after three weeks or gets worse. Other potential signs include:
According to the American Lung Association, it's important to be prepared for several key aspects of the journey. Here's what you can expect:
Take charge of your healthcare decisions. Ask questions, do your research, and ensure your needs are met. A friend, family member, or care coordinator can also help you advocate.
It is normal to experience a range of emotions. Find healthy ways to cope, like talking to friends and family, journaling, joining a support group, or seeking professional help.
Be prepared for your relationships to change. Some may grow closer, others more distant. It's also normal to feel misunderstood or to have different expectations from others.
Making healthy lifestyle choices is crucial. Quitting smoking, eating nutritious food, staying physically active, and managing stress are all vital for your recovery and long-term health.
Some side effects from treatment might linger. Discuss any ongoing symptoms with your doctor and ask about connecting with a palliative care specialist to help manage these effects and improve your quality of life.
Your care continues after treatment. Before your final appointment, get an "end-of-treatment summary" from your doctor that outlines your diagnosis, treatments, and future follow-up schedule.
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That sudden tightness after washing your face, the redness that won’t calm down, or the stinging from a product you’ve used for years—those aren’t just random flare-ups. They’re signals. Quiet, persistent warnings from your skin barrier, your body’s frontline defense system.
Most people don’t even realize they’ve been slowly breaking it down. From over-cleansing to layering too many actives, modern skincare trends often leave the barrier confused, stripped, and vulnerable. But the good news? This protective layer is also incredibly responsive. When you treat it right, it bounces back—stronger, smoother, and more resilient than before.
“The skin barrier is your body’s natural shield, protecting against pollution, bacteria, and moisture loss,” says dermatologist Dr. Rupika Singh. “When it’s healthy, your skin looks and feels balanced. But when it’s damaged—often due to over-cleansing, too many actives, or skipping moisturizer—your skin can become dry, red, sensitive, or breakout-prone.”
Your skin barrier lives in the stratum corneum, the outermost layer of your skin, and it functions much like a brick wall. The "bricks" are made up of dead skin cells, while the "mortar" that holds them together consists of lipids—specifically fatty acids, ceramides, and cholesterol. These lipids are essential for maintaining the skin’s structure and integrity. Inside the cells, Natural Moisturizing Factors (NMFs) act like water magnets, pulling in and retaining moisture to keep the skin hydrated. This highly organized system isn’t just for structure—it plays a crucial role in protection.
A healthy barrier keeps out irritants, allergens, bacteria, and pollution, while locking in hydration and essential nutrients. When functioning properly, your skin feels smooth, resilient, and balanced. But when this barrier is compromised, your skin quickly begins to send warning signs like dryness, tightness, redness, or increased sensitivity.
Here’s the tricky part, the first clue your barrier is under stress might be subtle—just a little dehydration. But if ignored, this can spiral into:
“Your skin doesn’t need more products—just smarter ones,” says Dr. Singh. “A resilient barrier means fewer flare-ups, faster recovery, and that healthy, glowing texture we’re all after.”
While environmental stressors like UV radiation, air pollution, and extreme weather are well-known culprits in weakening the skin barrier, the real damage often begins much closer to home—right at your bathroom sink. Daily skincare habits, when not done mindfully, can erode your skin’s natural defenses over time.
Over-exfoliating, for instance, strips away protective oils that are essential for barrier function. Using harsh cleansers can disrupt your skin’s natural pH, making it more vulnerable to irritants. Skipping moisturizer allows precious water to escape through transepidermal water loss, leaving your skin dry and more prone to damage. Overusing potent actives like retinol, AHAs, or BHAs may seem like a fast track to glowing skin, but they can actually compromise healthy cell turnover if not balanced properly. Even less obvious factors—like emotional stress or lack of sleep—can trigger inflammation that silently breaks down your barrier from within.
A healthy skin cycle typically lasts about 28 days, so with proper care, most skin barrier issues can start to improve within 2 to 4 weeks. That said, even a few days of barrier-friendly habits can bring relief from tightness and irritation but consistency is key. Think of barrier repair like physical rehab—it requires patience, the right tools, and a slow, methodical approach.
Dr. Singh advises starting by scaling back:
“The first step toward healing? Simplify your routine. Switch to a gentle, hydrating cleanser and reduce exfoliation to once or twice a week. Give your skin a break from strong actives like retinol or acids until it feels calmer.”
Stick to essentials: a cleanser, moisturizer, and sunscreen. Once your skin stabilizes, you can slowly reintroduce actives.
Use cleansers with a pH between 5.5 and 6.5, which match your skin’s natural acidity. Cream and oil-based formulas tend to be less disruptive than foam cleansers. Always wash with lukewarm water and pat dry instead of rubbing.
Hydration is about more than just applying moisturizer. Start with a hydrating serum containing hyaluronic acid or glycerin. While skin is still damp, apply a nourishing moisturizer with barrier-building ingredients like:
Dr. Singh emphasizes, “A nourishing moisturizer, applied twice a day, helps restore hydration and comfort.”
Even mild sun exposure silently chips away at your skin’s barrier integrity. A broad-spectrum SPF 30 or higher helps prevent this, while antioxidants like vitamin C or E add an extra layer of defense against environmental stressors.
When your barrier is strong, your skin naturally fends off signs of premature aging, inflammation, and sensitivity. But when it’s weak?
In other words, barrier health is the foundation of all good skincare. You can’t glow if your skin is busy trying to protect itself from further harm.
Most skin barrier issues are reversible. But you need to stay tuned in. If your skin suddenly feels off, flaky, or reacts to a product you’ve used for years, that’s your cue to reassess and recalibrate.
“So the next time your skin feels off, take it as a sign to slow down and tune in,” says Dr. Singh. “Often, what your skin really needs is less stress and more support—and that starts with protecting your barrier.”
Much like your gut or your immune system, your skin barrier is a living, breathing part of your health. Respect it, support it, and respond when it speaks up.
With a few thoughtful changes and a barrier-first mindset, you can transform not just how your skin looks, but how it behaves—resilient, calm, and confident in the face of whatever the world throws at it.
Dr. Rupika Singh is a Dermatologist and Founder at Akiya Aesthetics in India
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