A breast cancer diagnosis is life-altering. The ignored lump, the dismissed nipple changes, it’s only when the final diagnosis arrives that the gravity of it all sinks in. Well, good news is that with timely intervention, breast cancer can be treated and controlled. You fight through treatment, begin to heal, grow your hair back, regain your strength—and slowly, life starts to feel normal again. Now imagine being told it’s back. A relapse. It is of course a tough blow to take.

Recently, author and filmmaker Tahira Kashyap spoke up about her breast cancer relapse with strength and honesty, reminding us that she’s not alone in this fight. Many women face relapses, and it requires a lot of courage.

Dr. Sachin Trivedi, Director of Medical Oncology, HCG Hospitals Cancer Centre, Mumbai, explains, “Breast cancer can relapse locally, which means in the same breast or chest area, regionally (nearby lymph nodes), or distantly, which we call metastatic relapse where it spreads to other organs like the bones, liver, lungs, or brain.”

Dr. Hemkant Verma, Surgical Oncologist at Sharda Care Healthcity, adds that a relapse occurs when dormant cancer cells become active again. “It can be emotionally devastating, but with medical advancements, many relapsed cancers can still be managed effectively. Early detection and prompt action are our best tools.”

Local or regional relapses, especially those that occur after a few years, are most often treatable. Doctors say that the 5-year survival rate can still be as high as 60–80%, depending on individual cases. However, metastatic relapse (Stage IV) isn’t considered curable, but it is manageable. Many patients go on to live active lives for several years. What matters most is early detection, how aggressive the cancer is, where it has spread, and how well the body responds to treatment.

Minimising the risk of relapse

While treatment is key, there are lifestyle choices that can help reduce the risk of a recurrence like avoiding smoking, limiting alcohol intake, maintaining a healthy weight, following a balanced, antioxidant-rich diet and staying physically active.

Doctor warns that hormone replacement therapy should only be taken if it is medically advised.

"Staying in close contact with your oncology team is crucial. Regular follow-ups, checkups, and screenings play a vital role in catching any signs of recurrence early. Also, it’s important to address lingering side effects, whether it’s fatigue, menopause symptoms, bone loss, or lymphedema. Even something as simple as daily walks or gentle yoga can improve physical and mental health outcomes," adds Dr Sachin. Physical healing is only one part of the journey. Emotional and mental wellbeing matter just as much. Whether it’s therapy, support groups, mindfulness, journaling, or creative expression, it’s important to have an outlet and a support system.

Dr. Dinesh Pendharkar, Director, Sarvodaya Cancer Institute, adds that cancer relapse isn't a failure, it’s simply a new chapter. “Cancer is complex and can evolve over time, developing resistance to earlier treatments. Some cells may lie dormant and later reactivate. But today, we have many treatment options: chemotherapy, radiation, targeted therapies, immunotherapy, and even clinical trials.”

He reminds patients that science is advancing rapidly. “A relapse doesn’t mean the end. It’s just the beginning of a new strategy. With better tools, better treatments, and stronger support systems, this is a fight we can face with renewed hope. Think of it as a spiral, you have already climbed so far, and now you are rising to the next level.”

A team of US researchers has developed a novel nasal swab test, akin to those used to detect COVID-19 infections, which can spot early signs of Alzheimer's Disease -- affecting over 55 million people worldwide.

The condition is treatable in early stages to manage symptoms and slow cognitive decline. However, it remains the hardest to detect, affecting treatment outcomes. The brain changes can begin 10 to 20 years before symptoms become apparent.

The novel outpatient nasal swab, developed by Duke University researchers, has shown promise in picking up early biological changes linked to Alzheimer's. It can spot the degenerative condition, even before problems related to thinking and memory begin to appear.

"We want to be able to confirm Alzheimer's very early, before damage has a chance to build up in the brain," said Bradley J. Goldstein, professor at Duke University's School of Medicine.

"If we can diagnose people early enough, we might be able to start therapies that prevent them from ever developing clinical Alzheimer's," Goldstein added.

How Effective Was The Nasal Swab?

In the study, published in the journal Nature Communications, the team placed a gentle swab high inside the nose of 22 participants.

The swab collected thousands of nerve and immune cells to see which genes are active.

The analysis clearly differentiated people with early or diagnosed Alzheimer's from those without the disease -- 81 percent of the time. It also included people with no symptoms.

Alzheimer’s Disease: The Leading Cause of Dementia

Alzheimer's disease is one of the most common forms of dementia and mostly affects adults over the age of 65.

About 8.8 million Indians aged 60 and above are estimated to be living with Alzheimer's disease. Over seven million people in the US, 65 and older, live with the condition, and over 100,00 die from it annually.

Alzheimer's disease is believed to be caused by the development of toxic amyloid and beta proteins in the brain, which can accumulate and damage cells responsible for memory.

While there is no clear cause of Alzheimer's disease, experts believe it can develop due to genetic mutations and lifestyle choices, such as physical inactivity

unhealthy diet

social isolation.

Early symptoms of Alzheimer's disease include forgetting recent events or conversations. Other signs include:

• losing or misplacing things
• getting lost when walking or driving
• being confused, even in familiar places
• losing track of time
• difficulties solving problems or making decisions
• difficulties performing familiar tasks
• misjudging distances to objects visually.

Over time, Alzheimer's disease leads to serious memory loss and affects a person's ability to do everyday tasks.

Currently, there is no cure for this progressive brain disorder, and in advanced stages, loss of brain function can cause dehydration, poor nutrition, or infection. These complications can result in death.

Being physically active and taking part in activities and social interactions that stimulate the brain and maintain daily function can help prevent the condition.

The Human papillomavirus (HPV) vaccine is one of the most important advances in preventive healthcare, with the unique ability to prevent cancers.

Evidence consistently shows that the most appropriate age for HPV vaccination is between 9 and 14 years. At this stage, children develop a significantly stronger immune response, producing higher antibody titers than older adolescents and adults.

This enhanced immunogenicity translates into durable and highly effective protection and also allows simplified schedules, including the possibility of single-dose protection, thereby improving feasibility and coverage at a population level.

HPV Vaccine: Why Age 14 Matters The Most

The emphasis on vaccination by the age of 14 years is particularly important. Beyond this age, the immune response is relatively lower, and the number of doses required increases, making early vaccination both scientifically and programmatically more efficient.

Recognizing this, the Government of India has adopted a strategy of administering a single-dose HPV vaccine to adolescents up to 14 years of age through school- and community-based outreach programs. The program utilizes the Gardasil vaccine, which has an established track record of safety and efficacy over nearly two decades.

Equally critical is the timing of vaccination in relation to exposure. HPV is primarily transmitted through sexual contact, and vaccination before exposure ensures maximum effectiveness. Administering the vaccine in early adolescence provides protection well before any potential risk, making it a true preventive intervention with near-complete benefit.

Persistent infection with high-risk HPV types is a well-established cause of several cancers. In India, cervical cancer continues to be one of the leading causes of cancer-related illness and death among women. While HPV is also responsible for anal, penile, and oropharyngeal cancers, the burden of cervical cancer is substantially higher, which has historically led to a greater focus on vaccinating girls.

HPV: Are Boys At Risk?

However, HPV infection affects both genders. Boys are also at risk of HPV-related diseases, including anal and penile cancers, genital warts, and oropharyngeal cancers, the incidence of which is rising globally.

Vaccinating boys offers direct protection to them and also contributes to reducing transmission within the community. A broader, gender-inclusive approach has the potential to enhance population-level protection.

Public health agencies, including the World Health Organization, have emphasized HPV vaccination as a key strategy in cancer prevention and in reducing the long-term burden of non-communicable diseases.

HPV Vaccine: Part of Adolescent Health Check-ups

Integrating HPV vaccination into routine adolescent health check-ups can further normalize it as a standard preventive health measure. This approach can complement government efforts by encouraging participation from the private healthcare sector and improving overall uptake.

HPV vaccination in the 9–14 year age group is therefore not merely a recommendation; it is a time-sensitive, evidence-based intervention that can prevent cancers decades later. Strengthening awareness and ensuring timely vaccination will be critical in reducing the future burden of HPV-related cancers in India.

Heart diseases are viewed as a universal health concern, and advancements in cardiology have hugely improved diagnosis and treatment outcomes around the world. At the same time, emerging research is shedding more light on how cardiovascular disease affects women.

In India, this perspective is especially important. Of the more than 10 million deaths recorded annually in the country, nearly two million are attributed to diseases of the circulatory system, with women accounting for about 40% of these cases. Significantly, more than half of the nearly 800,000 cardiovascular deaths among Indian women each year occur prematurely, underscoring the importance of greater awareness, early detection, and timely medical care.

How Cardiac Research Has Evolved

It is evident that modern cardiology has been shaped by the findings from large, well-characterized populations of patients. The frameworks that have been established from such findings are the ones that guide the approaches that are currently used in the diagnosis and treatment of various forms of heart disease.

Such frameworks have been instrumental in the advancement of the management of various forms of cardiovascular diseases worldwide. As the research expands to include larger populations, there is an increased understanding that the manifestation of cardiovascular diseases differs from one group to another, particularly in females.

Recognizing Differences In Symptoms

This growing awareness is particularly useful in recognizing symptoms. Although women, like men, may experience chest pain as a symptom of a heart attack, there are other, less common symptoms that women may also experience.

These include fatigue, shortness of breath, nausea, dizziness, as well as neck, jaw, or back discomfort. The awareness of these symptoms will allow women to seek treatment sooner, as well as help healthcare providers better understand their symptoms.

The Role of Life Stages in Women’s Heart Health

Women’s heart health is influenced by various life stages and the hormonal changes that accompany them. For instance, after menopause, estrogen levels decline, and since this hormone offers some protective benefits for the heart, the risk of developing heart disease may gradually rise.

Certain pregnancy-related conditions, including gestational diabetes, preeclampsia, and high blood pressure during pregnancy, may also indicate a greater likelihood of cardiovascular disease later in life. Recognising these factors allows doctors to monitor heart health more closely and recommend preventive measures that support long-term wellbeing.

Strengthening Prevention And Early Detection

Prevention continues to be one of the most effective strategies for reducing heart disease. Regular health check-ups, along with monitoring blood pressure, cholesterol, and blood sugar, are essential for lowering cardiovascular risk. Adopting healthy lifestyle habits further supports long-term heart health. Awareness is equally important.

Symptoms such as fatigue or breathlessness are not always immediately linked to heart disease, particularly among women. Raising awareness about heart health can help people recognize early warning signs sooner and seek timely care.

Moving Toward More Inclusive Cardiac Care

Encouragingly, the field of cardiology is constantly evolving with the help of emerging research that is further enlightening us about the health of the heart in both men and women. With more women being included in research and better developments in diagnostic procedures, healthcare professionals are refining their strategies to deal with heart health.

Thus, by adopting the best strategies and emerging research about the health of women’s hearts, awareness and early intervention are the keys to better outcomes and reduced risks among women in India.