Credits: Health and me
Recent research highlights a concerning link between cardiovascular health, body weight, and breast cancer risk in postmenopausal women. New studies indicate that excess weight, especially in women with heart disease, may significantly increase the likelihood of developing hormone-driven breast cancers, raising questions about preventive strategies and personalized screening approaches.
While postmenopausal obesity has long been recognized as a risk factor for breast cancer, the nuances of how heart disease amplifies this risk are only now becoming clearer. A study led by Dr. Heinz Freisling from the International Agency for Research on Cancer analyzed over 168,000 postmenopausal women across Europe using data from the EPIC and UK Biobank cohorts. Researchers sought to determine whether excess weight poses a greater risk in women with cardiovascular disease (CVD) or type 2 diabetes.
The findings were significant: postmenopausal women who were overweight, and particularly those categorized as obese, faced an increased risk of developing invasive breast cancers. Women with a BMI over 35 experienced a 58% higher risk of ER-positive and PR-positive breast cancers compared to those with a healthy BMI of 18.5 to 25. Moreover, breast cancer mortality was more than twice as high among women in the highest obesity category.
Dr. Arvind Badiger, Technical Director at BDR Pharmaceuticals, explains the biological underpinnings, “Inflammation, insulin resistance, and hormonal disturbances found in CVD can drive tumorigenesis. Increased adipose tissue due to obesity is hormonally active and converts androgens to estrogens. Higher levels of estrogen may support hormone-receptor-positive breast cancers. Moreover, systemic inflammation caused by CVD releases pro-inflammatory cytokines and oxidative stressors that could possibly change DNA repair pathways and cellular proliferation.”
BMI, while commonly used in clinical settings, does not account for fat distribution. Dr. Badiger emphasizes that central obesity—measured through waist circumference or waist-to-hip ratio—may be a more accurate predictor of breast cancer risk. Visceral fat is metabolically active, promoting insulin resistance, chronic inflammation, and elevated estrogen production, all of which can drive cancer development.
“Clinically, we observe greater metabolic derangement in centrally obese patients, even those with a normal BMI. Measurement of waist circumference and metabolic profiling must be included in routine risk assessment,” Dr. Badiger notes.
Medications can also influence breast cancer risk and detection. Hormone replacement therapy (HRT), particularly combined estrogen-progestin regimens, has been associated with elevated breast cancer risk, while statins and metformin may offer protective effects due to their anti-inflammatory and anti-proliferative properties. Certain drugs, like corticosteroids, can obscure tumor markers and affect diagnostic clarity.
This underscores the importance of integrating a comprehensive medication history when assessing breast cancer risk in high-risk populations such as obese postmenopausal women with underlying cardiovascular conditions.
The American Institute for Cancer Research estimates that up to a third of U.S. breast cancers could be prevented if women maintained a healthy weight, engaged in regular physical activity, and avoided alcohol. The study also highlights that weight gain prevention is critical, as obesity remains one of the most modifiable risk factors for hormone-driven breast cancers.
Nutrition, exercise, and lifestyle interventions are particularly relevant for postmenopausal women with CVD, as these measures not only support heart health but also reduce systemic inflammation and improve metabolic profiles, which may lower cancer risk.
Experts recommend that risk evaluation for obese postmenopausal women should extend beyond routine mammography. Dr. Badiger advises including metabolic markers—such as insulin resistance, lipid profiles, C-reactive protein, and estradiol levels—alongside waist measurements. Additionally, clinicians should assess underlying cardiovascular disease, medication history, and lifestyle habits to provide a more nuanced understanding of breast cancer risk.
Customized screening programs that integrate clinical, biochemical, and lifestyle assessments can improve early detection and prevention in this high-risk group, ultimately reducing mortality rates associated with hormone-driven breast cancers.
The intersection of obesity, cardiovascular disease, and breast cancer risk in postmenopausal women highlights the urgent need for integrated prevention strategies. Understanding the biological mechanisms, monitoring central obesity, and implementing personalized screening and lifestyle interventions can provide women with actionable ways to reduce their risk and safeguard both heart and breast health.
Credits: Canva
The Centers for Disease Control and Prevention (CDC) has issued its 2025-26 outlook, predicting a respiratory virus season with similar peak hospitalizations from COVID-19, influenza, and respiratory syncytial virus (RSV) as last year. The agency also warns that COVID-19 hospitalization rates could rise if a variant with moderate immune-escape properties emerges.
While avoiding sick individuals is the first line of defense against the flu, cleaning and disinfecting your home after someone recovers is equally important to prevent the virus from spreading to others.
Before tackling flu germs, it’s crucial to understand the difference between cleaning and disinfecting. Cleaning removes visible dirt, dust, and germs using soap and water, while disinfecting targets remaining germs with products like sprays, wipes, or bleach. Experts recommend cleaning first, then disinfecting, for maximum effectiveness.
Viruses can survive on surfaces for up to 48 hours and on unwashed hands for about an hour. High-traffic areas in your home are most likely to harbor germs. Prioritize disinfecting:
If someone was sick in a vehicle, disinfect frequently touched surfaces such as steering wheels, door handles, seats, and seat belts. Disinfecting wipes are convenient, but always follow manufacturer instructions and wash your hands afterward.
In the kitchen, wash all utensils, dishes, and glasses in hot, soapy water or a dishwasher. Then disinfect:
Flu viruses can survive on soft surfaces like clothing, bedding, and towels. Wash all laundry in the hottest water recommended on care labels and dry thoroughly. Also, disinfect laundry baskets or hampers.
In bedrooms, disinfect doorknobs, bedside tables, bed frames, and drawer handles. Vacuum carpets and mop hard floors. For children, machine-wash soft toys and clean hard toys with soap and disinfectant.
Mobile phones, keyboards, tablets, and remote controls can carry harmful microorganisms. Clean screens with a soft, lint-free cloth dampened with soapy water, or use disinfecting wipes carefully, avoiding alcohol-based products that may damage electronics. Consider wipeable covers for easier disinfecting.
Open windows if outdoor temperatures are comfortable. Fresh air reduces airborne germs and helps when using disinfecting products. Proper ventilation ensures that lingering viruses don’t continue to spread indoors.
If you are still recovering from the flu, wait until you feel well before doing intensive cleaning. Recovery typically takes a week, but may take longer for those with underlying conditions or complications. Enlist help from family, friends, or professionals to avoid overexertion.
Flu is highly contagious, particularly when people spend more time indoors. Cleaning and disinfecting your home after recovery is vital to prevent spreading the virus. Start with high-traffic areas, then move to kitchens, bathrooms, bedrooms, and electronics. Always wear gloves and a mask when using disinfectants and follow instructions carefully.
By taking these precautions, you help protect your household and visitors from catching the flu, ensuring a safer and healthier home this season.
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Gina Marie Bakery, a company located in Connecticut, has issued a voluntary recall for several of its cookie products. The recall was announced after the company discovered a major issue with its packaging: it failed to list some important ingredients.
Specifically, the cookies may contain almonds, sesame, and several food colorings without declaring them on the label. The company is taking this action to ensure customer safety and has stopped all sales of the affected products until the problem is completely fixed.
The recall is a serious matter because of the health risks involved. For people with allergies to nuts, sesame, or certain food dyes, eating these cookies could cause a severe or even life-threatening allergic reaction.
Reactions can range from mild symptoms like hives and lip swelling to a dangerous condition called anaphylaxis, which can make it hard to breathe and can be fatal. Thankfully, no illnesses have been reported so far. This recall is a proactive step to prevent anyone from getting sick due to the incorrect labeling.
The recall includes several types of cookies sold in 1-pound and 2-pound plastic containers. The specific products are Italian Mixed Vanilla Cookies, Italian Sesame Cookies, and several others, all of which were distributed to various stores in Connecticut and parts of Massachusetts. If you have any of these cookies in your home, it's very important that you do not eat them. Instead, you should return them to the store where you bought them for a full refund. If you have any questions or concerns, you can call the company directly at 203-596-8007. Here are the specific products listed
In case you have consumed an allergen or believe you are having an allergic reaction, ensure that you take proper steps for the best outcomes. Anaphylaxis, which is a severe allergy reactionm is a very serious allergic reaction and a medical emergency. It requires immediate treatment with an adrenaline (epinephrine) injector, as a delay can be fatal. It’s important to know the difference between a mild reaction and a severe one.
What to do:
If you see these signs, stay with the person and call for help. Get the adrenaline device ready in case the reaction gets worse. A mild reaction might not always happen before a severe one begins.
Anaphylaxis is life-threatening. Look for any one of these signs:
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Something that started due to COVID-19 pandemic, a necessity to keep the workforce active and to keep the economy from collapsing, ‘work from home’ which is a working mode that allows people to work remotely, has becom very popular. However, this popularity is more focused on employees, rather than higher-ups of big corporates.
Many old-school workers prefer working from the office and advocate for the same, claiming working from home is not nearly as professional as working from the office. However, is that actually true? Many companies have been trying both work-modes, some settling in a hybrid-mode, which allows employees to work from home as well as the office.
So which work mode should companies go for? One of the main things companies want is productivity, so to look for the answer, they should look at proof of which mode allows their employees to be more productive. But how can they do that? To answer this, researchers conducted a long-standing study.
This four-year study from the University of South Australia confirms what many people have long suspected: having the choice to work from home is a powerful tool for improving happiness, health, and overall well-being. The research is especially important because it began before the pandemic and continued through it, offering a unique look at how remote work truly impacts people’s lives. The findings are clear: when working from home is an option rather than a requirement, it gives employees more control over their schedules, leading to a healthier and more balanced lifestyle.
One of the most immediate and significant benefits of working from home is the time saved by not commuting. The study found that remote workers gained an average of 30 extra minutes of sleep per night by avoiding their daily travel. This is a huge deal, as long commutes have been linked to high stress levels, fatigue, and poor mental health. By eliminating the daily grind of traffic or crowded public transport, employees reported feeling more rested, having more energy, and experiencing a greater sense of peace and calm in their daily lives.
The answer is no! The time saved from commuting wasn't just used for sleeping; it was redirected into other positive activities. Researchers found that about one-third of that saved time was used for personal hobbies and physical activity, showing a clear link between remote work and a healthier lifestyle. The study also revealed that people’s eating habits improved. With easier access to their own kitchens, workers were more likely to consume fruits, vegetables, and home-cooked meals, proving that working from home can influence not just your schedule, but also your nutrition and overall well-being.
A common concern among managers is that if employees aren’t in the office, they won't be as productive. However, this study challenges that idea directly. The research found that when employees are given the choice to work remotely, their performance is maintained and often even improves. The key is flexibility. When working from home was forced during lockdowns, many felt isolated and stressed, but when it's an option, their motivation and satisfaction rise. This shows that trusting employees to manage their own schedules can lead to better outcomes for both the company and the individual.
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