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Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder affecting social interaction, behavior, and communication. The etiology of autism is yet to be deciphered, although there is burgeoning evidence that an intimate relationship between the gut microbiome and the brain exists. In recent times, researchers have been investigating the possibility of using probiotics—the so-called "good bacteria"—as therapeutic interventions in children with autism. These supplements not only enhance digestive health but also reduce some of the behavioral symptoms, bringing hope to millions of families around the globe.
ASD is highly variable in its signs and symptoms. Some children have speech and communication problems, whereas others have sensory sensitivity or repetitive behaviors. Most have a problem with emotional regulation and social communication. Less openly spoken is that kids with autism very often have gastrointestinal (GI) problems like bloating, constipation, diarrhea, and irritable bowel syndrome (IBS).
Research has shown that people with autism tend to have an imbalance of their gut microbiota, with less healthy bacteria and more pathogenic bacteria like Clostridia. This has prompted scientists to study if normalization of the gut through probiotics would help improve symptoms of ASD.
Probiotics are live bacteria and yeasts that are beneficial to the digestive system. They are present in fermented foods such as yogurt, kefir, kimchi, and miso, and also in dietary supplements. Probiotics assist in keeping the good and bad bacteria in the gut in balance. These good microbes enhance digestion, boost the immune system, and can lower inflammation—factors that may contribute to autism symptoms.
Increased numbers of studies now indicate that probiotics may provide an effective complimentary treatment for individuals with ASD. In a more recent study revealed by the BMJ Journal, it was identified that children consuming probiotic supplements noticed a reduction of 47.77% in behavioral signs. The trial further indicated an attenuation of social withdrawal by 40% as well as the rate of repetition reduced by 37.77%. Further, enhancements in gastrointestinal well-being were observed, such as a rise of 18.18% in formed stools and a decrease of 6.66% in watery stools.
The brain and the gut are closely linked by the gut-brain axis, a two-way communication network between the nervous system and the digestive system. The US Department of Health and National Institutes of Health (NIH) place significant importance on gut microbiota in postnatal brain development. Scientists feel that alterations in gut bacteria can be responsible for neurological and behavioral abnormalities in children with autism.
Ohio State University Study links kids with ASD were noted to have lower amounts of Faecalibacterium prausnitzii, a gut bacterium linked to good gut health.
Another research stated that how chemicals made by gut bacteria affect autism behaviors.
A 2016 International Meeting for Autism Research (IMFAR) detected Haemophilus parainfluenzae in the stools of autistic children, tying it to gastrointestinal distress and behavioral difficulties.
Based on this evidence, numerous scientists now think that enhancing gut health with probiotics may help ease symptoms of autism.
Individuals with autism have a higher tendency to experience GI disorders like IBS and leaky gut syndrome, which results when toxic bacteria and toxins escape into the blood through a weakened intestinal lining. Leaky gut symptoms can be:
By restoring the balance of gut flora, probiotics can potentially treat these gastrointestinal disturbances. Probiotic strains including Lactobacillus acidophilus, L. rhamnosus GG, L. reuteri, and Bifidobacterium have been effective in maintaining intestinal health and relieving symptoms of children with inflammatory bowel disease (IBD), a condition typically observed in children with ASD. Saccharomyces boulardii, a probiotic yeast, has also been reported to be responsible for the relief of obsessive-compulsive behaviors, which are characteristically observed in children with autism.
When choosing a probiotic supplement for an autistic child, parents need to take the following into account:
Strain Diversity: A variety of bacterial strains is best for maintaining gut health.
Scientific Support: Opt for probiotics that have scientific evidence, like Lactobacillus and Bifidobacterium species.
Live Cultures: Make sure the product has active, live bacteria that can withstand stomach acid and travel to the intestines.
Consultation with a Physician: Always consult with a physician prior to the initiation of probiotics, particularly for children with weakened immune systems.
Although probiotics are regarded as safe, side effects can be in the form of slight gas, bloating, constipation, or allergic reactions. Nevertheless, these are generally tolerated as the body acclimatizes to the new bacterial load.
The US Food and Drug Administration (FDA) oversees probiotics as foods, not as drugs, so their efficacy and safety are not under the same level of intense testing as pharmaceuticals. However, experts in the health field are unanimous in saying that probiotics are safe for children as well as adults when used properly.
Although probiotics cannot be considered a sole treatment for autism, they can be used to augment current therapies like behavioral therapy, speech therapy, and special education programs. Stool analysis can also be used to identify the most appropriate probiotic strains for a child's individual needs so that a customized approach to gut health can be adopted.
Autism can be difficult to handle by families, but research on the gut-brain relationship provides new promise. While researchers keep finding the connection between gut health and neurological function, probiotics can become the hoped-for component in the overall treatment of autism.
Improvements in microbiome science, as well as greater knowledge of probiotics, are a giant leap toward enhancing the quality of life in ASD-affected children. Although larger clinical trials are necessary to delineate the role of probiotics in autism treatment comprehensively, the early results are promising. Parents willing to use probiotics for the child should visit a healthcare practitioner to decide on the most suitable method for their child's specific requirements.
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Reading non-fiction books is not my cup of tea, while they are informative and important to read, when I read for pleasure, I want to immerse myself in a world that could never be. Reading fiction books like the Harry Potter series, Percy Jackson books and others like the Dragon Rider, were the reason I enjoyed reading. Often using these books as a means to escape difficult feelings, I never even realized how reading these books transformed my mental health, along with my perspective.
Reading plays an important role for your mental health; books offer numerous advantages for one's mental well-being. Whether the preference lies with short stories or lengthy novels, colorful picture books or digital formats, various forms of literature can provide valuable benefits. This piece will explore several key reasons why reading is so beneficial for mental health.
According to a 2022 PLoS One study, reading fiction can improve people's mental well-being. The researchers conducted five different studies to see how various ways of engaging with fiction affect individuals. These methods includes recalling past fiction reading experiences, being instructed to read fiction, discussing fiction in comparison to non-fiction, and discussing different types of fiction.
The research shows that books had a positive influence on people's mood and emotions. However, it appears that simply reading fiction might not lead to an immediate improvement in mental well-being. The brain seems to require a period of processing and understanding the story before positive effects can be observed.
Mental Health First Aid England, a social enterprise that offers guidance and training for mental health in workspaces, explains that whether the preference lies with short stories or lengthy novels, colorful picture books or digital formats, various forms of literature can provide valuable benefits. Here are some ways it helps us.
Reading captivating books brings joy and immersion, making time disappear. Finishing a good story can evoke sadness or eagerness for more, highlighting reading's positive impact.
Engrossing oneself in a book for just six minutes can significantly reduce stress by lowering heart rate and easing tension, outperforming other relaxation methods.
Reading offers an escape from the real world, providing a coping mechanism, especially in childhood. This immersion can be transformative, influencing how we interact with the world.
Reading fiction enhances empathy, improving the ability to understand others' feelings and thoughts, temporarily boosting this crucial social skill.
Lifelong cognitive activities like reading slow down memory loss and reduce mental decline in later life compared to less stimulating pursuits.
Discussing books in reading groups can significantly improve mental health, aiding concentration, emotional understanding, self-awareness, and meaningful discussions.
Discussing books fosters a sense of control and independence, benefiting mental well-being. It provides a positive and safe way to process challenging topics.
Reading for pleasure in adolescence enhances academic performance, social engagement, and personal development, offering insights into adult life.
Research confirms that reading increases intelligence, leading to a larger vocabulary, broader knowledge, and improved verbal skills.
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On the day of World Malaria Day, as we raise awareness on the dangers posed by this mosquito-borne disease, let's delve a bit deeper into how malaria is different from the other mosquito-borne diseases.
Both malaria and dengue are transmitted by female mosquitoes and cause severe illness in humans. There are certain similarities between the two diseases and the mosquito species, which is why the patients and diagnoses are often confused.
As per the co-Principal Investigator, Dr Charles Guissou, for the Target Malaria, a vector control research alliance's Target Malaria Burkina Faso at the Institut de Recherche en Sciences de la Santé, "Dengue and malaria are two very different diseases caused by different pathogens and different mosquito species." “Misdiagnosis between malaria and dengue is common, and this can then contribute to inappropriate medical care.”
Every year, malaria causes 200 million cases worldwide, leading to 600,000 deaths. Many of these cases are from Africa, where children and pregnant women pay the highest price. The World Health Organization (WHO) has also reported that in 2022, Africa was home to 95% of malaria cases and 95% of malaria deaths. The global incidence of dengue has grown significantly in recent decades. Cases reported to WHO increased from 505,430 in 2000 to 6.5 million in 2023.
Dr Ajay Gupta, Head & Director - Internal Medicine, Max Super Speciality Hospital, Vaishali also points out the key differences between malaria and other mosquito-borne diseases. He says, "Malaria is caused by Plasmodium parasites, transmitted through the bite of infected Anopheles mosquitoes. In contrast, dengue, chikungunya, and Zika viruses are transmitted by Aedes mosquitoes. This distinction in the type of mosquito also reflects differences in peak biting times—Anopheles mosquitoes bite during nighttime, while Aedes mosquitoes are daytime biters."
"Another key difference lies in complications and disease progression. Malaria, especially caused by Plasmodium falciparum, can progress rapidly to severe illness with cerebral involvement, anemia, kidney failure, and even death if not promptly treated. Dengue, on the other hand, is known for a sudden drop in platelet count and risk of hemorrhage. Chikungunya commonly leads to prolonged joint pain, sometimes lasting weeks or even months after the infection clears," notes the doctor.
There is also a difference between how the mosquitoes that spread dengue and malaria.
It is responsible for spreading dengue and has white stripes down the center of the thorax. It also has a resting position where its body is kept low and parallel to the ground, with the proboscis angled downward. It is slender, and the wings have distinctive white markings.
It is responsible for causing malaria and has long palps. It is dark in color and the resting position follows it abdomen at a 45-degree angle to the surface.
Zika is a viral infection also transmitted by Aedes mosquitoes, which is the first difference from malaria, in the species of mosquito that causes it. As per the WHO, those with Zika virus do not tend to experience symptoms, and if they do, it includes rash, fever, conjunctivitis, and muscle and joint pain. The symptoms are also what makes it different. They appear from 3 to 14 days after being bitten.
This is also caused by Aedes mosquitoes, and the symptoms usually appear within 4 to 8 days after infection. The symptoms include fever, joint pain, headaches, and nausea.
This is caused by Aedes and haemagogus mosquitoes. People who are infected with this virus do not get sick and experience only mild symptoms. As per the Centers for Disease Control and Prevention (CDC), 12% of people who have symptoms develop serious illness, which includes organ failure and jaundice.
The key difference between all other mosquito-borne diseases and malaria is the species of the mosquito that causes it. While all the others are caused by Aedes, malaria is caused by the Anopheles.
According to the scientists at the University of Emory, in their 2010 study, they found that beer produces an odour in your body that is irresistible to the malaria-carrying mosquitoes.
There are rare strains of this disease which could in fact take months or even years to get diagnosed. In one of the rare cases, malaria was diagnosed four years later the individuals were infected, reported UK's The Telegraph.
In 1943, Disney was tasked with creating a film to promote public health awareness. The result? The Winged Scourge — a rather unusual PSA where the Seven Dwarfs learn how to fight off malaria-spreading mosquitoes.
George Washington battled malaria, and the disease is also believed to have claimed the lives of Pope Leo and Pope Sixtus—just a few of its prominent victims.
The doctor also points out that diagnosis and treatment also vary. "Malaria is typically confirmed with a blood smear or rapid diagnostic test and is treated with specific antimalarial drugs. There is no antiviral treatment for dengue, chikungunya, or Zika—management is primarily supportive," he says.
In India, we often see a spike in these illnesses during and after the monsoon season, However, malaria control efforts—such as early diagnosis, insecticide-treated bed nets, and vector control—have significantly reduced the burden in recent years.
"Preventive strategies like eliminating stagnant water, using mosquito repellents, and ensuring proper sanitation are universally effective. But recognizing the distinct nature of malaria is key to prompt diagnosis and management," notes Dr Gupta.
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In 2022, about 1 in 5, which is around 702,880, people died due to cardiovascular diseases (CVD) in the United States. There are many factors around you that affect your heart health. Things like what food you eat, whether the area you live in is polluted or not and also what kind of lifestyle you lead. There are many risk factors for heart diseases like high blood pressure, high cholesterol levels or smoking, which are key risk factors according to the Centers of Disease Control and Prevention (CDC). The CDC explains about 47% of US citizens have at least one of these three risk factors.
Another risk factor could be the place you live in. A new study published in the European Society of Cardiology April 2025 revealed that the walkability of a neighborhood can play a big role for your cardiovascular health. The study revealed that individuals living in areas with low walkability had a 5% higher risk of developing CVD compared to those in very walkable neighborhoods. Interestingly, even in neighborhoods that improved in walkability over time, the risk of CVD remained about 5% higher for those who started in low-walkability areas, possibly due to the lasting effects of earlier sedentary habits.
To figure out how walkable a neighborhood is, the researchers in the study looked at several things. They checked how many people lived in the area (population density), how many shops were nearby, if there were parks and green spaces, and if there were sidewalks to walk on. They also considered if different types of buildings were mixed together (like shops and homes), if there was good public transportation, and how well the streets connected to each other. All these things together helped them decide how easy it was to walk around in a certain neighborhood.
Researchers studied over three million adults who were at least 40 years old and didn't have any heart problems when the study started. The researchers kept track of how walkable each person's neighborhood was for 13 years. They also checked if the walkability of these neighborhoods stayed the same, got better, or got worse during that time.
The findings of this study support what doctors have known for a long time: moving your body is good for your health, especially your heart. What's interesting is that you don't need to do intense workouts to see the benefits. Even small amounts of activity, like walking your dog in a park or carrying your groceries home from the store, can make a difference. These little bursts of energy throughout the day can add up and help lower your risk of getting heart disease.
A report from 2023 from Smart Growth America found that less than 7% of people in America actually live in very walkable urban neighborhoods. Interestingly, studies have shown that minority groups often live in more walkable neighborhoods. However, these same groups are also more likely to suffer from heart and blood sugar problems. This might be because even in walkable areas, factors like safety, clean environments, and good sidewalks and parks might not be available in all neighborhoods.
Even if you don't live in a very walkable area, there are still things you can do to move more. You might need to get a little creative! You can try lifting weights or doing yoga while you watch TV. If you drive to the store, park a little further away so you have to walk more. Take the stairs instead of the elevator. Stand up and move around when you're on the phone, have walking meetings if possible, and make sure to get up and stretch every hour.
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