Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder affecting social interaction, behavior, and communication. The etiology of autism is yet to be deciphered, although there is burgeoning evidence that an intimate relationship between the gut microbiome and the brain exists. In recent times, researchers have been investigating the possibility of using probiotics—the so-called "good bacteria"—as therapeutic interventions in children with autism. These supplements not only enhance digestive health but also reduce some of the behavioral symptoms, bringing hope to millions of families around the globe.

ASD is highly variable in its signs and symptoms. Some children have speech and communication problems, whereas others have sensory sensitivity or repetitive behaviors. Most have a problem with emotional regulation and social communication. Less openly spoken is that kids with autism very often have gastrointestinal (GI) problems like bloating, constipation, diarrhea, and irritable bowel syndrome (IBS).

Research has shown that people with autism tend to have an imbalance of their gut microbiota, with less healthy bacteria and more pathogenic bacteria like Clostridia. This has prompted scientists to study if normalization of the gut through probiotics would help improve symptoms of ASD.

Role of Probiotics in Gut Health

Probiotics are live bacteria and yeasts that are beneficial to the digestive system. They are present in fermented foods such as yogurt, kefir, kimchi, and miso, and also in dietary supplements. Probiotics assist in keeping the good and bad bacteria in the gut in balance. These good microbes enhance digestion, boost the immune system, and can lower inflammation—factors that may contribute to autism symptoms.

Increased numbers of studies now indicate that probiotics may provide an effective complimentary treatment for individuals with ASD. In a more recent study revealed by the BMJ Journal, it was identified that children consuming probiotic supplements noticed a reduction of 47.77% in behavioral signs. The trial further indicated an attenuation of social withdrawal by 40% as well as the rate of repetition reduced by 37.77%. Further, enhancements in gastrointestinal well-being were observed, such as a rise of 18.18% in formed stools and a decrease of 6.66% in watery stools.

The Autism-Gut-Brain Connection

The brain and the gut are closely linked by the gut-brain axis, a two-way communication network between the nervous system and the digestive system. The US Department of Health and National Institutes of Health (NIH) place significant importance on gut microbiota in postnatal brain development. Scientists feel that alterations in gut bacteria can be responsible for neurological and behavioral abnormalities in children with autism.

Ohio State University Study links kids with ASD were noted to have lower amounts of Faecalibacterium prausnitzii, a gut bacterium linked to good gut health.

Another research stated that how chemicals made by gut bacteria affect autism behaviors.

A 2016 International Meeting for Autism Research (IMFAR) detected Haemophilus parainfluenzae in the stools of autistic children, tying it to gastrointestinal distress and behavioral difficulties.

Based on this evidence, numerous scientists now think that enhancing gut health with probiotics may help ease symptoms of autism.

Probiotics and Digestive Health in Autism

Individuals with autism have a higher tendency to experience GI disorders like IBS and leaky gut syndrome, which results when toxic bacteria and toxins escape into the blood through a weakened intestinal lining. Leaky gut symptoms can be:

• Constipation
• Bloating
• Excess gas
• Nutrient deficiencies
• Food allergies

By restoring the balance of gut flora, probiotics can potentially treat these gastrointestinal disturbances. Probiotic strains including Lactobacillus acidophilus, L. rhamnosus GG, L. reuteri, and Bifidobacterium have been effective in maintaining intestinal health and relieving symptoms of children with inflammatory bowel disease (IBD), a condition typically observed in children with ASD. Saccharomyces boulardii, a probiotic yeast, has also been reported to be responsible for the relief of obsessive-compulsive behaviors, which are characteristically observed in children with autism.

How to Choose the Right Probiotic for Autism?

When choosing a probiotic supplement for an autistic child, parents need to take the following into account:

Strain Diversity: A variety of bacterial strains is best for maintaining gut health.

Scientific Support: Opt for probiotics that have scientific evidence, like Lactobacillus and Bifidobacterium species.

Live Cultures: Make sure the product has active, live bacteria that can withstand stomach acid and travel to the intestines.

Consultation with a Physician: Always consult with a physician prior to the initiation of probiotics, particularly for children with weakened immune systems.

Although probiotics are regarded as safe, side effects can be in the form of slight gas, bloating, constipation, or allergic reactions. Nevertheless, these are generally tolerated as the body acclimatizes to the new bacterial load.

Are Probiotics a Safe and Effective Treatment for Autism?

The US Food and Drug Administration (FDA) oversees probiotics as foods, not as drugs, so their efficacy and safety are not under the same level of intense testing as pharmaceuticals. However, experts in the health field are unanimous in saying that probiotics are safe for children as well as adults when used properly.

Although probiotics cannot be considered a sole treatment for autism, they can be used to augment current therapies like behavioral therapy, speech therapy, and special education programs. Stool analysis can also be used to identify the most appropriate probiotic strains for a child's individual needs so that a customized approach to gut health can be adopted.

Autism can be difficult to handle by families, but research on the gut-brain relationship provides new promise. While researchers keep finding the connection between gut health and neurological function, probiotics can become the hoped-for component in the overall treatment of autism.

Improvements in microbiome science, as well as greater knowledge of probiotics, are a giant leap toward enhancing the quality of life in ASD-affected children. Although larger clinical trials are necessary to delineate the role of probiotics in autism treatment comprehensively, the early results are promising. Parents willing to use probiotics for the child should visit a healthcare practitioner to decide on the most suitable method for their child's specific requirements.

As per the World Health Organization (WHO), globally, over 1.2 billion people ages 30 to 79 have hypertension. The number has increased from 650 million in 1990 to 1.2 billion in 2021. This increase is attributed to many factors, including lifestyle factors, which include salty indulgence, stress, and screen time which has been increased. These three impact your blood pressure levels, know how.

What Are The Three S Worsening Your Blood Pressure?

Salt

As per the Harvard Heart Publishing, an average American consumes the equivalent of about 1 1/2 teaspoon of salt per day, which is 50% more than the recommended amount.

About a third of healthy people and about 60% of people with high blood pressure are salt sensitive.

How does salt affects blood pressure?

When you consume too much sodium, your body holds on to extra water to balance the sodium levels. This added fluid increases the volume of blood in your vessels, which in turn raises your blood pressure and forces your heart to work harder. High sodium intake can also reduce the effectiveness of certain blood pressure medications. For example, diuretics help eliminate excess sodium and water, while vasodilators work by relaxing the blood vessels. However, a high-sodium diet makes your body retain fluid again, refilling those relaxed vessels and undoing the medication's effects.

Stress

As per the official publication of State Medical Society of Wisconsin, stress can cause hypertension through repeated blood pressure elevations as well as by stimulation of the nervous system to produce large amounts of vasoconstricting hormones that increase blood pressure. Factors affecting blood pressure through stress include white coat hypertension, job strain, race, social environment, and emotional distress.

As per National Health and Nutrition Examination Survey, around 50 million American adults live with hypertension, defined as a systolic blood pressure over 139 mm Hg or diastolic pressure over 89 mm Hg. In about 95% of these cases, the condition is classified as "essential" hypertension, meaning there’s no single identifiable cause. However, experts agree that multiple factors—including stress—can contribute to rising blood pressure in these individuals.

Screentime

As per a 2024 study published in Cureus, hypertension is a major risk factor for coronary artery disease. The study links the increased accessibility of smartphones with the increasing hypertension.

This study explored the relationship between screen time and blood pressure (BP) among young adults.

The study also noted that higher screen time was more common among individuals using multiple devices. The prevalence of elevated BP in the sample was 35.8%, aligning with national data and raising concerns about the cardiovascular health of young adults.

Previous studies support these concerns. For instance, Nang et al. and Martinez-Gomez et al. linked prolonged TV viewing to higher BP and an adverse cardiovascular risk profile in adolescents. However, these relied on self-reported data. Other risk factors, such as age, gender, obesity, inactivity, and substance use, have also been linked to hypertension.

Women’s reproductive health is a sensitive subject. Even though there have been many advancements in women’s healthcare, large gaps in research and medical well-being of women have been observed. The general lack of information regarding women’s healthcare and education have also been highlighted in the recent years.

While you may think it is not a matter of urgency, a new report found a very concerning toxin in tampons, levels of which were higher than what is even allowed in drinking water.

A new report from two groups, the Women's Environmental Network (WEN) and Pesticide Action Network UK, has raised serious concerns. They found harmful chemicals in many of the menstrual products sold in regular stores across Britain. The study was particularly worried about finding pesticides, especially glyphosate, which is the most common weed killer used worldwide, in these products that women use in a very sensitive part of their bodies.

Disturbing Levels of Pesticides Detected

The findings are quite shocking. Tampons are a largely used menstruation product, which soaks the menstrual blood by insertion in the vaginal canal. The World Health Organization, a global health authority, has said that glyphosate probably causes cancer. Even more alarmingly, one box of tampons had levels of glyphosate that were 40 times higher than what's legally allowed in drinking water!

It's thought this happens because the pesticide might be sprayed on the cotton crops that are used to make tampons. The report also found another dangerous chemical called chlorpyrifos in some tampons. This is an insecticide that's actually banned in the UK because it can harm the brain and nervous system.

The report was very clear about how serious this is: they said that for some chemicals, there's no safe amount, so any trace found in period products should be less than what can even be detected.

Direct Threat to Health

There's worry about how these chemicals might affect health. This is because a part of the body that absorbs things very easily, the vagina, lets chemicals skip the body's natural cleaning systems and go straight into the blood. People are saying this isn't just careless, it's actually dangerous. They also feel it's wrong that these kinds of chemicals are still in period products today.

Lack of Regulation and Impact on Farmers

The report pointed out a major problem: there are no specific rules in the UK for these products. Manufacturers don't have to tell you what's in their products, and there are no laws to stop pesticide residue from ending up in the final product you buy.

The issue also affects cotton farmers. The report highlighted that "cotton farmers are being exposed to toxic pesticides at concerning levels." Many of these farmers are women, and they face health risks every day from working with these dangerous pesticides both on their farms and even in their homes.

Demands for Clearer Information and Change

People are strongly demanding that the industry be more open. It's simply not okay that users don't know what's in products they use on such private parts of their bodies. There's an urgent need for companies to be transparent (show all ingredients), take accountability (be responsible for their products), and make real changes in how things are done. This is because everyone who has a period deserves better and safer products.

The report asks the government to act quickly:

• Test period products very strictly.
• Make it a legal rule for companies to list every ingredient and extra chemical.
• Include organic, disposable period products in free school programs.

Concern regarding pollution and how it affects our health is a worry that affects many of us worldwide. As years pass on by, the pollution levels are also increasing, and so is our mortality risk. The World Health Organization (WHO) explains that exposure to air pollution is strongly linked with stroke, ischaemic heart disease, lung diseases etc. However, these are not the only things you must worry about when it comes to air pollution exposure. A new study shows that it could also affect the way our brain functions.

A study from Italy, published in a science journal called iScience, found a really important clue in our genes. It seems that when we breathe in polluted air, it can actually change how our genes work in the brain. Think of it like flipping a switch that creates the perfect conditions for diseases like Alzheimer's and Parkinson's to start growing.

Early Warning Signs and High-Risk Groups

The researchers saw some worrying changes even in young adults. Their brain tissue showed signs of DNA damage that looked a lot like what you'd see in someone with Alzheimer's – but decades before they would normally be diagnosed. This is a huge red flag.

Certain jobs also put people at a higher risk. If you're a miner, factory worker, or driver, you're exposed to more polluted air. Even people who work with plastics face a hidden danger from tiny particles called nanoparticles that can get into their brains.

But here's some good news: this discovery could mean doctors can check for these changes without needing to do anything invasive, like surgery. They might be able to test for something called extracellular vesicles. These are like tiny packages that carry material from damaged brain cells. So, if we can test for these packages, it could give us an early warning sign from the brain itself.

Understanding the Complexities and Taking Precautions

It's clear that being generally unhealthy and breathing polluted air from a young age can increase your risk of these brain conditions. However, we still need a lot more research to fully understand how everything is connected. Experts from News Medical have pointed out that studying air pollution is tricky because the air we breathe in the real world is a mix of many different pollutants.

To help protect yourself on days when pollution levels are high, organizations like Asthma + Lung UK suggest some simple steps:

• Stay indoors as much as possible.
• Avoid exercising outside, especially vigorous activity.
• If you're walking, try to stay away from busy roads with heavy traffic.
• Keep your car windows closed when driving in traffic.
• If you do want to be active outdoors, try to do it earlier in the day, as the air tends to be cleaner then.

Looking Ahead: Prevention and Policy

There's a big call for more research to understand how air pollution affects younger people and other parts of our brain's thinking abilities. The results of this research could lead to exciting new ways to prevent these diseases. It could also push for better safety rules in workplaces, stricter environmental standards to clean up our air, and even new laws to protect public health from air pollution.