Credit: Canva
Organ failure kills thousands of people every year. While transplantation is the solution, it is not always viable. There is a global shortage of organs, and to cater to this, researchers are now trying to develop organs in labs or even 3D print them. One such organ is the kidney. But there is more to it. During a recent experiment, researchers discovered that this organ can actually regenerate itself.
Human beings are born with two kidneys, which filter about a half cup of blood every minute, removing wastes and extra water to make urine. It has long been thought that kidney cells didn't reproduce much once the organ was fully formed. However, a new study published in Cell Reports in May showed that kidneys regenerate and repair themselves throughout life.
"This research tells us that the kidney is in no way a static organ," said Benjamin Dekel, MD, PhD, a senior author of the paper and associate professor of pediatrics at Sackler, as well as head of the Pediatric Stem Cell Research Institute at the Sheba Medical Center in Israel. "The kidney, incredibly, rejuvenates itself and continues to generate specialized kidney cells all the time, " added Irving Weissman, MD, professor of pathology and of developmental biology and director of the Stanford Institute,who is the other senior author.
The study was conducted on mice and shows that "the kidney regenerates itself like a tree". Instead of a single type of kidney stem cell that can replace any lost or damaged kidney tissue, slightly more specialised stem cells segments of the kidney give rise to new cells within each type of kidney tissue." It's like a tree with branches in which each branch takes care of its growth instead of being dependent on the trunk," Dekel said.
There is a special protein involved. The decision these cells make to grow is made through the activation of cellular pathways involving a protein called Wnt. Even though populations of kidney epithelial cells look the same, the most robust kidney-forming capacity can be traced back to precursor cells in which Wnt is activated and that can only grow into certain types of specialized kidney tissue,
The realization that Wnt signaling is responsible for the growth of new kidney tissue offers a therapeutic target to promote or restore the regenerative capacity of the kidneys," he said. "We may be able to turn on the Wnt pathway to generate new kidney-forming cells." This finding can prove to be particularly useful for scientists who grow kidney cells in the lab.
Despite this path-breaking discovery, researchers say that it is not a viable option to grow a whole kidney in the lab. To grow a whole kidney in the laboratory would be complicated because we would need to orchestrate the activities of many different kinds of precursor cells using just the right stimuli," Dekel said. "It's not like the blood and immune system, which can be reconstituted from one type of stem cell," he said.
Credit: Canva
Diseases related to the heart are often considered conditions that affect older individuals, but in recent times, we are witnessing an increase in cardiovascular issues among the young urban professionals, particularly those who are aged between 20 and 40.
Factors that contribute most to the health of the heart are mainly increasing work pressure, irregular lifestyles, poor sleep patterns, and chronic stress as well.
Modern lifestyles have also created conditions where many individuals expose their hearts to continuous stress in an unknowing way.
Stress is one of the most underestimated risk factors of heart disease. When a prolonged stress is experienced by a person, certain hormones are released by the body, such as adrenaline and cortisol, which also increase the heart rate and blood pressure.
During the short-term challenges, chronic stress usually keeps the body in a constant state of alertness. With the passage of time, this can also lead to persistent high blood pressure, inflammation, and increased strain on the heart, which also raises the risk of cardiovascular disease.
Young professionals who usually have long working hours, deal with tight deadlines each and every day, or experience job insecurity, are quite vulnerable to stress-related heart problems.
Lifestyle habits are also affecting the health of the heart, such as:
Early warning signs such as fatigue, palpitations, breathlessness, and unexplained chest discomfort are also observed in many younger patients. These symptoms are usually untreated or attributed to stress.
However, such signs should not be ignored, especially if they occur on a frequent basis.
Maintaining the health of the heart also requires a great effort to balance the demands of work with healthy habits.
Doctors recommend:
In today’s fast-paced world, safeguarding the health of the heart should not be considered as a long-term investment in the overall well-being.
TikTok screengrab (@queencitytrends)
Across social media, videos of mothers shaving their daughters’ upper-lip hair have been going viral. In many clips, parents say they are trying to protect their children from bullying about facial hair, something many women recall experiencing during their own childhood. Some of these videos show girls as young as 10 or 12 getting their first facial shave at home.
The conversation gained major traction in 2023 when influencer Vidya Gopalan posted a video of herself shaving her 12-year-old daughter’s facial hair. The clip clocked millions of views and sparked strong reactions. While many viewers praised the mother for being proactive, others felt the practice introduces children to beauty pressures far too early.
Similar videos continue to trend today, often framed as an act of care from parents who want their children to feel confident. But dermatologists say the issue is more complicated than it looks online.
Experts point out that children’s skin is very different from adult skin. The protective barrier is still developing, which means it is more vulnerable to irritation and injury.
When shaving is done too early or too frequently, it can cause redness, cuts, razor bumps and sometimes infections. Using adult razors, dull blades or harsh products can make the situation worse. Even small nicks on delicate facial skin can lead to inflammation or long-lasting irritation.
Dermatologists note that shaving itself is not inherently dangerous if done correctly and occasionally. However, it should not become a routine practice for very young children simply because it is trending online.
Instead, any decision about hair removal should be taken carefully, with proper hygiene and supervision.
One reason many parents feel comfortable allowing shaving is the belief that hair will grow back thicker anyway, so removing it early does not change much.
Experts say this idea is a long-standing myth.
When hair regrows after shaving, the blunt edge of the cut hair can make it appear darker or thicker. In reality, the hair shaft itself has not changed. Studies in dermatology have repeatedly shown that shaving does not alter hair thickness, color or growth rate.
However, frequent shaving may still irritate sensitive skin, which is why dermatologists recommend caution when it comes to young children.
The debate intensified further after reports surfaced about an eight-year-old undergoing laser hair removal. That revelation shocked many people online and pushed the conversation beyond simple grooming.
Dermatologists stress that laser hair removal is generally designed for teenagers or adults whose hormones have stabilized. During childhood, hair growth patterns can still change significantly as the body develops. Because of this, such procedures are rarely recommended for younger children.
The concern is not only medical but also psychological. Starting cosmetic treatments too early may reinforce the idea that natural body features need to be “fixed.”
Experts say the larger conversation should not revolve only around hair removal techniques. It should also address how children learn to view their bodies.
Facial hair during puberty is normal, and it varies widely depending on genetics and hormones. In countries like India, where darker hair is common, many children may notice upper-lip hair earlier than their peers.
Instead of immediately removing it, dermatologists encourage parents to talk openly with their children about body changes. Helping children build confidence and understand that these changes are natural can be just as important as addressing appearance concerns.
If a child feels genuinely uncomfortable, gentler options such as a soft facial trimmer or consulting a dermatologist may be considered. But experts say the goal should not be to rush into grooming habits simply because social media has normalized them.
Sometimes, the most important step is helping children realize that their bodies are not a problem that needs fixing.
Credit: Canva
An international team of researchers has developed an artificial intelligence (AI)-based tool that can significantly improve care for glaucoma -- a leading cause of irreversible blindness worldwide, according to a study published in The Lancet Primary Care journal today.
Researchers led by those from the University of Lisbon in Portugal found that the AI-based screening tool halved the number of unnecessary referrals for glaucoma.
The study, released during the Glaucoma Awareness Week, also showed an accuracy level at par with human eye doctors.
"The high accuracy at excluding people without glaucoma is especially important, as false alarms can lead to unnecessary hospital visits, patient anxiety, and added strain on healthcare services," the researchers said.
According to the researchers, AI-based screening could:
The study was carried out at a single screening center in Lisbon, Portugal, in 2023.
The experts screened 671 adults aged 55-65 for glaucoma via the AI tool, analyzing images of the eyes. The images were then independently graded by six glaucoma experts.
The AI-tool:
While modelling studies suggest that screening could substantially reduce glaucoma-related visual impairment and blindness, barriers include the need for specialised diagnostic equipment and trained personnel, particularly in low- and middle-income countries, and the intrinsically low positive predictive value of screening tests.
In such a scenario, the new study showed that "AI may provide a more viable option than population-wide screening", which may seem impractical.
Glaucoma is a chronic disease that affects an estimated 80 million individuals globally, according to the World Glaucoma Association.
It is a progressive, degenerative disorder of the optic nerve that produces characteristic visual field damage.
The disease stems from a long asymptomatic phase, resulting in substantial underdiagnosis and delayed treatment.
Even in high-income countries, up to 50 percent of individuals with glaucoma remain undiagnosed, frequently presenting moderate to advanced disease at first detection.
By the year 2040, it is estimated that there will be 22 million individuals worldwide who are blind from glaucoma.
When to see a doctor for glaucoma:
© 2024 Bennett, Coleman & Company Limited