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For decades, food has not only been an important source of nutrition but also of emotion and culture. It's the way we share ourselves, celebrate, and find solace. But what occurs when food starts to lose its appeal? For a lot of people on mainstream weight-loss drugs such as Ozempic and Wegovy, this has become a very personal and physiological challenge. One of the most fascinating and sometimes disturbing—side effects noted is a stark dislike of once-loved foods, especially meat and fried foods. Why?
As weight-loss drugs like Ozempic (semaglutide) and its alternative Wegovy become more popular, so too are first-person accounts of changed taste and appetite. Though these drugs are praised for their ability to control weight, users are now reporting an unexpected change in how they feel about food—one that science is just starting to completely grasp.
Ozempic is a GLP-1 receptor agonist that was first developed to treat type 2 diabetes. Its cousin, Wegovy, has the same active ingredient—semaglutide—but with the specific approval from the FDA for weight reduction. Both of these medications copy a hormone called GLP-1 (glucagon-like peptide-1), which the body naturally secretes from the gut in reaction to food. When the drug binds to the GLP-1 receptors of the brain and body, the medication assists with maintaining blood sugar levels, slowing down gastric emptying, and curbing appetite.
But scientists now believe its impacts extend well past the ability to make individuals full. GLP-1 receptors also occur within regions of the brain used to process rewards as well as human taste buds. This dual influence—upon taste and appetite—may account for the reason so many users can find themselves in disgust at eating foods that before they enjoyed highly.
Former Minnesota food reporter Alyssa Fraser gives a powerful illustration. A once enthusiastic home cook who loved to prepare her go-to chicken and vegetable recipes, she found herself no longer liking those same dishes after beginning Wegovy. Finding meat to taste like the "barnyard" it originated from and wine strangely "vegetal," Fraser didn't just lose her appetite but underwent a shift in sense perception.
This experience is not singular. Countless individuals online on forums as well as medical research have noted the same issues—meat too pungent, foods fried too weighty, even desserts losing desire after a mouthful or two. In several instances, meals are no longer an enjoyment, but rather become more of an instrumental necessity.
Psychobiologists have proposed that GLP-1 medications induce a decoupling between "liking" and "wanting" food. In daily life, individuals tend to keep consuming calorie-rich foods even if they don't like them, motivated by habit or emotional reward. GLP-1 agonists seem to break this cycle by suppressing the brain's dopamine-mediated "wanting" response, allowing for easier resistance to indulgent foods.
In a way, your brain is being re-conditioned not to pursue the sensory high of food—especially from sugar, salt, and fat. This may be one of the reasons why greasy, fried, and heavy foods now feel too much or even disgusting.
While much of the existing data is reliant on self-reporting, increasingly studies are starting to investigate these effects in more systematic ways. One source, published in Food Quality and Preference, discovered that individuals taking GLP-1 drugs ate less refined grains, red meat, and sweets compared to controls. They also ate more fruit, more leafy greens, and drank more water—gravitating toward a naturally healthier diet, even with no deliberate intention.
But much of this evidence is based on small groups or animal studies. University of Arkansas professor of food policy economics Brandon McFadden cautions that self-reporting can be sketchy. But the trend is unmistakable: individuals taking these drugs take in fewer calories—sometimes as many as 700 fewer a day—primarily because food is less appealing.
Another study presented at the Endocrine Society's 2024 conference provided some neurological insight. Brain scans of women on semaglutide showed increased activity in areas related to taste processing, particularly in response to sweet stimuli. This suggests that taste sensitivity may increase, making intense flavors—like the umami richness of meat or the oiliness of fried foods—overwhelming or off-putting.
For others, such changes are a blessing. Lower cravings make weight loss easier and more sustainable. But others experience a deeper emotional price tag. As Fraser has said, "Not only am I not cooking or really taking an interest in food—if I want it, it's sweets. And even then, if it's super sweet, I'll take a bite or two, and I'm like, I gotta put it down."
There's a quiet mourning that accompanies losing the enjoyment of food—a ritual greater than sustenance. Preparing, sharing, and relishing meals are a part of many individuals' identities and social existence. When that pleasure disappears, some users feel severed from a component of themselves.
Rebalancing your relationship with food isn't about rules, though—regaining joy, balance, and awareness. Food shouldn't ever become the enemy or another item on the "stress about that" list; if it's begun to take on that shape, these six shifts in attitude will remind you what nourishment is all about.
Let's get this straight—dieting isn't the hero of your health story. Skipping meals or eliminating entire food groups can have the opposite effect, leaving you mentally drained and physically starved. Rather than running after food rules, begin listening to what your body truly needs.
When did you last really taste your food? If you're typically eating on the move, in front of screens, or while multi-tasking, you're not alone. Slow down. Sit down to eat. Savor each bite. Mindful eating not only amplifies pleasure, but naturally supports wiser food choices.
Hunger doesn't have to be physical. Other times, we eat out of boredom, stress, or celebration. The next time you grab a snack, take a moment and ask yourself: What am I really feeling? That pause could help you spot patterns you weren't aware of.
Picture yourself eating just enough to be energized, satisfied, but not full—that's your sweet spot. It's not about calorie counting, but more about learning to listen to your fullness cues and trusting them again. The more you pay attention, the more sensitive you'll become.
Trapped in the social media cycle of ideal bodies and fitness trends? It's time to break free. Actual health isn't about losing weight—it's about feeling strong, full of energy, and connected to your body. Get rid of the filters and redefine wellness for you.
You don't have to sort it out all by yourself. A registered dietitian can be your good friend co-pilot—giving you evidence-based guidance, debunking misconceptions, and steering you in the direction of a healthier, guilt-free partnership with food that really works with your life.
As semaglutide-based drugs such as Ozempic and Wegovy continue to redefine weight loss and diabetes treatment, their influence on food desires brings an additional layer of sophistication. The alteration in taste, hunger, and desire are very real, but intensely personal. While some embrace the disconnection from food as a kind of liberation, others lament the erasure of the pleasure of cooking.
Until more definitive studies are available, patients and clinicians should be informed about these sensory and psychological side effects. And most importantly, anyone with marked changes in appetite or taste should talk to their healthcare provider—not just to control side effects but also to have a healthy, balanced relationship with food.
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Many people are now aware that microplastics have entered the food and drink we consume every day. Seafood, in particular, has been widely discussed, as studies have found plastic particles in nearly all samples of fish and shellfish tested.
Plastic production has been rising steadily since the 1960s, with around eight million metric tonnes entering the oceans each year. Over time, sunlight and wave action break this waste down into microplastics, tiny fragments measuring less than five millimetres. These particles persist in the environment and gradually move through the food chain.
Writing in The Conversation, environmental expert Catherine Rolph explains that while seafood has received most of the attention, it is far from the only source of exposure. Public awareness is growing, she notes, but microplastics are found in many everyday foods, often in higher amounts than people expect.
Chewing gum is one of the more surprising sources of microplastics. Most gum is made from a synthetic base containing plastics and rubber, along with added sweeteners and flavours. As the gum is chewed, microplastic particles are released. Research suggests that just one gram of gum can release hundreds of these particles.
Even gums labelled as natural appear to release similar amounts, which points to contamination during production or packaging. Studies also show that most microplastics are released within the first few minutes of chewing.
Salt may seem like a basic, natural ingredient, but studies show that microplastics are present in the vast majority of salt products tested worldwide. In fact, contamination has been found to be higher in some land-based salts, such as Himalayan salt, than in sea salt.
Experts believe much of this contamination occurs during processing and packaging. Plastic grinders can also add to the problem by releasing additional particles while grinding.
Microplastics have been detected in a wide range of fruits and vegetables. Very small plastic particles can enter plants through their roots, while larger fragments may settle on their surfaces.
Research has found that apples and carrots tend to contain higher levels compared to other produce, while leafy greens such as lettuce show lower contamination. Despite this, experts stress that the health benefits of fruits and vegetables remain far greater than the potential risks.
Hot drinks are another overlooked source of microplastic exposure. Tea leaves, coffee, milk, and disposable takeaway cups can all contribute to contamination. Heat increases the release of microplastics, which is why hot beverages often contain more particles than cold drinks. Using loose-leaf tea and reusable cups made from glass or metal can help reduce exposure.
While most seafood does contain microplastics, studies suggest the actual levels are often lower than people assume. Filter-feeding shellfish such as mussels have been found to contain relatively small amounts compared to some processed foods and drinks prepared using plastic materials.
Experts say completely avoiding microplastics is unlikely, but small changes can help reduce exposure. Storing food in glass containers, avoiding plastic packaging where possible, and using non-plastic grinders and utensils can make a difference.
Switching from bottled water to tap water may also lower intake, as studies suggest single-use plastic bottles release more microplastics than tap water.
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As a harsh cold wave swept across North India, doctors noticed a quiet but worrying trend inside emergency rooms—more people were showing up dehydrated, even though temperatures were at their lowest. Health and Me spoke to Dr. Swadesh Kumar, Cluster Head – Emergency and Trauma Care & Casualty, Gurugram, to understand why winter dehydration is often missed and how it can turn dangerous if ignored.
Winter is usually associated with hot drinks, cozy layers and fewer reminders to sip water. According to Dr. Kumar, this mindset is exactly where the problem begins. “People assume that because they’re not sweating or feeling thirsty, their body doesn’t need as much water. That’s a misconception,” he explains.
During cold spells, thirst signals are naturally suppressed. At the same time, the body continues to lose fluids through dry air, indoor heating and even breathing. “The loss is gradual and silent, which makes winter dehydration harder to spot,” Dr. Kumar adds.
Hospitals across northern states reported a seasonal increase in dehydration-related complications during the cold wave. These weren’t always dramatic cases. Patients often came in with dizziness, fatigue, confusion or sudden changes in blood pressure.
“In many emergency visits, dehydration wasn’t suspected initially because there was no heat exposure or fever,” says Dr. Kumar. This delay allowed symptoms to worsen before treatment was started.
Low fluid intake doesn’t just cause weakness, it can aggravate underlying health problems. When the body is dehydrated, blood becomes thicker, increasing the risk of clot formation. This is particularly dangerous for older adults and people with heart disease.
Kidneys are also affected. Reduced hydration puts extra strain on them, sometimes leading to acute kidney injury. “We see patients with palpitations, fainting spells and extreme weakness, only to later realize dehydration is the root cause,” Dr. Kumar notes.
Winter illnesses further complicate the situation. Fever, rapid breathing and certain medications increase fluid loss. Yet many people intentionally avoid drinking water to reduce bathroom visits in the cold.
“This combination is especially risky for children and the elderly,” Dr. Kumar says. Children depend on caregivers for hydration reminders, while older adults naturally feel less thirsty. Both groups can slip into dehydration quickly during winter infections.
Room heaters and blowers dry out indoor air, leading to unnoticed moisture loss through the skin and breath. People spending long hours indoors often underestimate this effect.
Early signs like dry lips, headaches and muscle cramps are commonly ignored. By the time medical help is sought, dehydration may already have disrupted blood pressure or electrolyte balance.
Unlike summer dehydration, winter dehydration doesn’t come with intense thirst. Dark urine, reduced urination, constant tiredness and mild confusion are frequent clues but are often blamed on cold weather or poor sleep.
“In severe cases, dehydration can contribute to sudden falls, worsening chronic illnesses and emergency admissions,” Dr. Kumar warns.
Doctors advise treating hydration as a routine, not a response to thirst. Warm water, soups, stews and herbal drinks are practical winter options. Fruits with high water content also help, even when appetite is low.
“Monitor urine color, limit excess caffeine and be extra careful if you have a chronic condition,” Dr. Kumar advises.
The cold wave is a reminder that dehydration isn’t just a summer problem. Even in winter, the body needs adequate water to function, and ignoring that need can quietly turn into a medical emergency.
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With 28 percent of adults in the UK now classified as obese and another 36 percent considered overweight, it is unsurprising that weight-loss injections have surged in popularity. Estimates suggest around 1.5 million people are currently using these jabs each month.
While the injections can lead to significant weight loss, experts warn that they come with notable risks and often fail to address the root causes of weight gain. Mike Wakeman, a researcher, pharmacist, and founder of Evera Nutrition, explained how these medications work and why they may fall short in the long term.
“These medicines mainly act by increasing two gut hormones, GLP-1 and GIP. These hormones reduce appetite, increase feelings of fullness, and slow stomach emptying,” he said. “The problem is that many people rely on medication alone.”
Wakeman pointed out that several underlying contributors to weight gain are frequently overlooked. “Stress, poor sleep, alcohol misuse, binge eating, and even certain medications or hormonal and medical conditions, such as an underactive thyroid, are often ignored when discussing weight issues,” he said. “If these factors are not addressed, they will still be present at the end of treatment and are likely to trigger weight regain.”
Recent research supports this concern. Studies have found that participants regained almost all of the weight they lost within a year of stopping weight-loss injections.
Side effects linked to weight-loss jabs are common and include nausea, vomiting, constipation, and acid reflux. More serious health issues have also been reported in some individuals. These include pancreatitis, gallbladder problems, and depression. Rapid weight loss can result in muscle loss, while hair thinning and vision problems have also been associated with the use of these injections.
According to specialists, growing scientific evidence suggests that certain natural ingredients may help support healthy weight loss when combined with proper diet and lifestyle changes, without the same side-effect profile seen with injections.
“The good news is that some natural ingredients can mimic the effects of GLP-1,” Mike said. “These include glucomannan, which is a type of fibre, along with resveratrol, hibiscus, green tea, berberine, curcumin, cinnamon, and mulberry.”
Explaining the science behind these ingredients, Wakeman broke down how each one may support weight management.
“Glucomannan is a natural fibre derived from the konjac root. It expands in the gut, helping you feel full, and may also increase GLP-1 levels,” he said, as per Mirror. “Resveratrol, found in foods such as grapes, has been shown to significantly reduce body weight, waist circumference, and BMI.”
“Hibiscus has been shown to reduce obesity, abdominal fat, and blood lipid levels,” he added. “Catechins like EGCG, found in green tea, have been linked to meaningful reductions in body weight, BMI, and waist circumference, particularly at higher doses and over longer periods, when combined with a healthy diet and exercise. They also help boost metabolism and fat burning.”
“Berberine is a plant compound that, according to a meta-analysis of 12 studies, reduces body weight, BMI, and waist circumference,” he said. “Curcumin, the active compound in turmeric, has also shown strong evidence. An umbrella meta-analysis covering 14 systematic reviews and 39 randomised controlled trials found that curcumin supplementation reduces body weight, BMI, and waist size, while also improving blood sugar and blood fat levels.”
“Cinnamon may help reduce weight by improving blood sugar control,” Wakeman continued. “A meta-analysis of 12 trials involving 734 people found that cinnamon intake lowered body weight, BMI, and waist circumference. Mulberry has also shown anti-obesity effects, including activating brown fat.”
Wakeman also noted that certain ingredients may work by slowing the breakdown of GLP-1 and GIP. “Some compounds may help inhibit Dipeptidyl Peptidase-4, or DPP-4,” he said. “DPP-4 is an enzyme that breaks down GLP-1 and GIP. When this enzyme is blocked, these hormones remain active for longer.”
Ingredients that may play a role in DPP-4 inhibition include curcumin, resveratrol, cinnamon, maritime pine bark extract, blackcurrant, mulberry, quercetin, and rosemary.
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