Name: Big breakthrough: New blood test could identify pregnant women at risk for preeclampsia
Uploaded: 2024-10-22T17:42:55+05:30
Duration: 1 min 33 s

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preeclampsia

blood pressure

pregnant women

fibrinogen

albumin

inflammation

fluid balance

risk

care

Preeclampsia is a serious condition that affects pregnant women, causing high blood pressure and leading to life-threatening complications. But now, doctors may have a new way to predict the risk of preeclampsia during labor — with just a routine blood test.According to a new study presented at the American Society of Anesthesiologists, analyzing two proteins in the blood — fibrinogen and albumin — could help doctors assess a woman's risk. These proteins are key indicators of inflammation and fluid balance in the body. An elevated fibrinogen-to-albumin ratio, or FAR, could signal a higher risk of developing preeclampsia.

Big breakthrough: New blood test could identify pregnant women at risk for preeclampsia

big breakthrough: new blood test could identify pregnant women at risk for preeclampsia

Ishita Roy

Why That Persistent Ache Might Not Be ‘Just An Injury’, Overlooked Signs That Could Signal Bone Cancer

why that persistent ache might not be ‘just an injury’, overlooked signs that could signal bone cancer

Blocking Brain-Liver Signals Could Stop Cancer-Related Weight Loss, New Study Reveals

blocking brain-liver signals could stop cancer-related weight loss, new study reveals

Blue Fugate Mystery - What Caused The Surprising Blue Skin Condition Of This Family Since The 1800s?

blue fugate mystery - what caused the surprising blue skin condition of this family since the 1800s?

AI Diet Advice Turns Dangerous: ChatGPT Plan Lands Man In ER With Bromide Poisoning

ai diet advice turns dangerous: chatgpt plan lands man in er with bromide poisoning

sarcoma

Sarcoma Awareness Month

cancer

bone cancer

heart cancer

sarcoma awareness

mrinal gounder

Sarcoma, often called the "forgotten cancer," and this is why it is important to talk about it. July marks the Sarcoma Awareness Month. It is a rare and complex group of cancers that can affect anyone, anywhere in the body. In an exclusive interview, Dr. Mrinal Gounder,  a globally recognized sarcoma expert and medical oncologist at Memorial Sloan Kettering Cancer Center, New York, who is also the Physician Ambassador to India and Asia, stresses the need for early, accurate diagnosis and specialized care. While mostly unpredictable, awareness, genetic counseling, and timely medical attention can make a life-saving difference.

Sarcoma, often called the "forgotten cancer," and this is why it is important to talk about it. July marks the Sarcoma Awareness Month. It is a rare and complex group of cancers that can affect anyone, anywhere in the body. In an exclusive interview, Dr. Mrinal Gounder,  a globally recognized sarcoma expert and medical oncologist at Memorial Sloan Kettering Cancer Center, New York, who is also the Physician Ambassador to India and Asia, stresses the need for early, accurate diagnosis and specialized care. While mostly unpredictable, awareness, genetic counseling, and timely medical attention can make a life-saving difference.

EXCLUSIVE INTERVIEW with MSK, New York Physician Dr Mrinal Gounder On Sarcoma Awareness Month

exclusive interview with msk, new york physician dr mrinal gounder on sarcoma awareness month

Kalpana Sharma

Colon Cancer Screenings Help Catch The Deadly Disease Earlier - Is Pencil Thin Stool A Sign Or Myth?

colon cancer screenings help catch the deadly disease earlier - is pencil thin stool a sign or myth?

Influencer Tana Mongeau Lost 6lbs Weight In 48 Hours On Mounjaro—Now Warns To 'Never Do It Again'

influencer tana mongeau lost 6lbs weight in 48 hours on mounjaro—now warns to 'never do it again'

When to Worry About Heart Palpitations: How to Tell If That Racing or Skipping Beat Is Just Stress or a Medical Warning

when to worry about heart palpitations: how to tell if that racing or skipping beat is just stress or a medical warning

beyond the stethoscope

guru n reddy

doctors day 2025

national doctors day 2025

who heals the healer

From unnecessary procedures to unclear billing, Dr Guru N Reddy, MD, FACP, FACG, FASGE, AGAF, Founder &amp; Chairman, Continental Hospitals, Chief of Gastroenterology &amp; Liver Diseases, calls out the silent wrongs in the system. In the first episode of Beyond the Stethoscope, the veteran doctor holds up a mirror to medical malpractice, exposing how lack of transparency and greed are eroding trust in healthcare. This isn’t just about bad doctors, it’s about a broken mindset.

From unnecessary procedures to unclear billing, Dr Guru N Reddy, MD, FACP, FACG, FASGE, AGAF, Founder & Chairman, Continental Hospitals, Chief of Gastroenterology & Liver Diseases, calls out the silent wrongs in the system. In the first episode of Beyond the Stethoscope, the veteran doctor holds up a mirror to medical malpractice, exposing how lack of transparency and greed are eroding trust in healthcare. This isn’t just about bad doctors, it’s about a broken mindset.

Doctors Day 2025: Beyond The Stethoscope, Episode 1

doctors day 2025: beyond the stethoscope, episode 1

‘It Feels Like The Safety Of Childhood’: Why Adult Pacifiers In China Are Helping People Quit Smoking, Sleep Better And Stress Less?

‘it feels like the safety of childhood’: why adult pacifiers in china are helping people quit smoking, sleep better and stress less?

Ozempic Users Found To Age Back By More Than 3 Years, Finds New Trial; Peer Review Pending

ozempic users found to age back by more than 3 years, finds new trial; peer review pending

Health

dentistry

oral health

dental care

implants

gum disease

saliva

cavities

dental floss

World Health Day

Every year on April 7, World Health Day is observed, this year, our team in an exclusive interview with Lt Gen Dr Vimal Arora spoke to him about the importance of dental health and how it can tell a lot about your overall health. As Dr Arora rightly says, your oral health is like a "mirror" to your overall health. Watch the full interview here.

World Health Day 2025: Why Your Dental Health Is Important, An Exclusive Conversation With Lt Gen Dr Vimal Arora

world health day 2025: why your dental health is important, an exclusive conversation with lt gen dr vimal arora

What Is Mermaiding? The Aquatic Fitness Trend Taking the Internet by Storm

what is mermaiding? the aquatic fitness trend taking the internet by storm

Actress Eva Amurri Says Her Back Hurts Looking at Before Photo: How Breast Reduction Can Relieve Chronic Back, Neck and Shoulder Pain

actress eva amurri says her back hurts looking at before photo: how breast reduction can relieve chronic back, neck and shoulder pain

5 Foods You Think Are Bad But Secretly Healthy, According to a Nutritionist

5 foods you think are bad but secretly healthy, according to a nutritionist

mawra hocane

fitness routine

radiant glow

skincare tips

pilates

healthy diet

workout regimen

fitness secrets

glowing skin

celebrity fitness

Mawra Hocane, the actress known for her role in Sanam Teri Kasam, has recently shared some breathtaking wedding photos on Instagram, leaving netizens in awe of her glowing skin and fit physique. Achieving this level of fitness and radiance doesn’t happen by accident. It’s the result of Mawra’s dedication to her fitness routine and a solid skincare regimen. But it’s not just about working out—her healthy diet and lifestyle choices play a huge role too.Watch the video for more details

Mawra Hocane's Fitness Routine: The Secrets to Her Radiant Glow

mawra hocane's fitness routine: the secrets to her radiant glow

This Naturally Occurring Molecule May Have Ozempic-like Benefits Without The Side Effects

ozempic

alternative to ozempic

weight loss

semiglutide

natural ozempic

glp 1

nutrition

diet & nutrition

What if we tell you that a naturally occurring molecule can do wonders like Ozempic, but without the side effects. Hard to believe, isn't it? However, Stanford Medicine researchers have found a molecule that acts similar to semaglutide, by suppressing appetite and reducing body weight. The trials on animals have also shown that it worked without some of the drug's side effects, including nausea, constipation and significant loss of muscle mass. <br /><br />The paper was published on March 5 in <em>Nature</em>, and led by Laetitia Coassolo, PhD, Kartin Svensson, assistant professor of pathology.<br /><br /><h4>What Is This Naturally Occurring Molecule?<br /></h4><br />This newly discovered molecule is BRP. This acts, though, in a separate pathway, but has similar metabolic effects. It can activate different neurons in the brain and offer a more targeted approach to body weight reduction. <br /><br />Stanford Medicine's release quoted Svensson, PhD, who explained, "the receptors targeted by semaglutide are found in the brain but also in the gut, pancreas and other tissues. That’s why Ozempic has widespread effects including slowing the movement of food through the digestive tract and lowering blood sugar levels. In contrast, BRP appears to act specifically in the hypothalamus, which controls appetite and metabolism.”<br /><br />Svensson has also co-founded a company to launch clinical trials of the molecule in humans in the near future. <br /><br /><h4>How Was The Study Conducted?<br /></h4><br />This study would not have been possible without the help of AI, notes the release. Researchers used AI to sift through dozens of proteins in a group called prohormones.<br /><br />Prohormones are molecules that do not do anything on their own at first. They become active only after being cut into smaller pieces, called peptides, by other proteins. Some of these peptides then act as hormones, controlling important functions in the body, such as energy use in the brain and other organs.<br /><br />Each prohormone can be cut in different ways, producing many possible peptides. Among these, only a few actually work as hormones, while most are just byproducts of protein breakdown. Traditional lab methods make it hard to find the useful peptides in this mix.<br /><br />The researchers focused on an enzyme called prohormone convertase 1/3, which cuts prohormones at specific points in the amino acid chain. This enzyme has been linked to obesity in humans. One of the peptides it produces is GLP-1, which helps control appetite and blood sugar levels. <br /><br />The drug semaglutide works by mimicking GLP-1. The team wanted to see if there were other peptides from this enzyme that also play a role in energy metabolism.<br /><br />To do this, they created a computer program called Peptide Predictor. Instead of manually sorting through proteins, the program scanned all 20,000 human protein-coding genes to find likely cutting sites for prohormone convertase 1/3. They focused only on proteins that are secreted outside the cell, a key feature of hormones, and that had at least four cutting sites. This narrowed the list to 373 prohormones.<br /><br />The program predicted that these could produce 2,683 unique peptides. The team then looked at those most likely to act in the brain and tested 100 of them, including GLP-1, on lab-grown nerve cells.<br /><br />GLP-1 increased cell activity about three times compared to normal cells, as expected. But one small peptide, just 12 amino acids long, increased activity tenfold. They named it BRP, based on the name of its parent protein BRINP2.<br /><br /><h4>What Did The Result Reveal?<br /></h4><br />Tests on lean mice and minipigs showed promising results. An injection of BRP before feeding reduced food intake by up to 50% over the next hour. In obese mice, daily injections for two weeks led to an average weight loss of 3 grams, mostly fat, while untreated mice gained about 3 grams. The treated mice also had better blood sugar control.<br /><br />Importantly, BRP did not change the animals’ movement, water intake, anxiety levels, or digestion. It also works through different brain and body pathways than GLP-1 or semaglutide, which could make it useful for people who do not respond well to those drugs.<br /><br /><h4>What's Next?<br /></h4><br />Researchers now want to find the exact cell receptors BRP binds to and figure out how to make its effects last longer in the body. If it proves safe and effective in humans, BRP could offer a new option for treating obesity.<br /><br />The study was a collaboration between scientists at the University of California, Berkeley, the University of Minnesota, and the University of British Columbia.<br /><meta content="cms.next" name="cmsei" />

this naturally occurring molecule may have ozempic-like benefits without the side effects

FDA Vaccination Chief Vinay Prasad Returns To Job Within Days After Quitting Under Pressure, Who Is He?

FDA Vaccine Chief

indian origin vinay prasad

health news

Vinay Prasad

who is vinay prasad

Dr. Vinay Prasad, who resigned just two weeks ago as head of the Food and Drug Administration’s vaccines and gene therapy division, is returning to the agency in a rare reversal. The Department of Health and Human Services confirmed his reinstatement on Saturday, with spokesperson Andrew Nixon saying Prasad will resume leadership of the Center for Biologics Evaluation and Research at the FDA’s request.<br /><br />Prasad’s ouster in late July followed sustained pressure from biotech executives, patient advocacy groups, conservative figures, and right-wing activist Laura Loomer. Loomer, who has previously demonstrated influence over Trump administration personnel decisions, accused Prasad of being a “progressive leftist saboteur” and, more recently, a “Marxist,” pointing to his past praise for Senator Bernie Sanders.<br /><br /><h4>Resignation Amid Political and Public Backlash<br /></h4><br />The decision to push him out came after weeks of mounting criticism, fueled in part by a series of editorials faulting him for denying drug approvals and ordering a pause on a medication linked to several patient deaths. Loomer and other critics also drew attention to comments Prasad had made about Donald Trump before joining the administration.<br /><br />Before his resignation on July 29, both Health Secretary Robert F. Kennedy Jr. and FDA Commissioner Dr. Marty Makary defended Prasad, calling him a scientist of exceptional rigor. Makary publicly described him as “impeccable,” while Kennedy privately noted his preference for Prasad’s cautious approach to vaccine approvals.<br /><br /><h4>A Record of Tough Regulatory Calls<br /></h4><br />Since joining the FDA, Prasad has drawn attention for decisions that prioritized safety and efficacy over speed. He declined to approve multiple high-profile drugs, including treatments for advanced skin cancer and heart conditions in patients with a rare muscle disorder, arguing that the agency should resist approving high-cost drugs with uncertain benefits.<br /><br />In May, he played a key role in limiting the use of COVID-19 vaccines to those over 65 and people with health conditions that put them at greater risk of severe illness. Under his leadership, the FDA restricted approvals for new shots from Novavax and Moderna and set stricter testing requirements for future vaccines.<br /><br />His most controversial move came when he ordered the halt of Sarepta Therapeutics’ gene therapy shipments for Duchenne muscular dystrophy after two teenage boys and a 51-year-old man died in cases deemed related to the medication. The decision met fierce resistance from families of patients and advocates for expanded access to experimental treatments, as well as criticism from political figures and editorial boards. The FDA later reversed the suspension, allowing shipments for younger patients to resume.<br /><br /><h4>A History of Outspoken Criticism<br /></h4><br />Before his government role, Prasad was an oncologist and epidemiologist at the University of California, San Francisco, where he gained a large following through Substack, YouTube, and other platforms. Known for sharp and sometimes expletive-laced critiques of public health policy, he frequently challenged the FDA’s pandemic-era decisions and called for greater scrutiny of medical products.<br /><br />His reinstatement underscores the influence Kennedy and Makary still hold within the Trump administration and signals that, despite political headwinds, Prasad’s hardline approach to drug and vaccine oversight will continue to shape U.S. healthcare policy.<br /><meta content="cms.next" name="cmsei" />

fda vaccination chief vinay prasad returns to job within days after quitting under pressure, who is he?

Waking Up With Red Eyes? 7 Possible Causes Your Body Might Be Sending These Warnings

Tanya Dutt

red eyes in morning

causes of red eyes

red eyes health warning

morning eye redness

eye irritation causes

red eyes and fatigue

morning eye problems

That first glance in the mirror can say a lot about your night and your health. If your eyes are bloodshot red even before you’ve had coffee, it’s not just a skincare issue. Morning eye redness is often a sign that something’s off and that your body is signalling to something- whether it’s as simple as dry air in your bedroom or as serious as glaucoma.<br /><br />The catch? Red eyes are not a diagnosis. They may be a symptom, and one that can be indicative of many conditions. Getting the reason behind the redness is crucial to alleviating it and safeguarding your sight. Here's an examination of the seven most frequent causes — and why you should take them seriously.<br /><br /><h2>1. Sleep Apnea and CPAP Side Effects<br /></h2><br />Obstructive sleep apnea not only interferes with your breathing — it may interfere with your eye health as well. Those who have this condition tend to sleep with their eyes half-open, drying them out. And for those who are on CPAP therapy, the constant flow of pressurized air can blow up into the eyelids, drying them further.<br /><br />Sleep apnea dry eyes are also more severe in the morning and may make the whites of your eyes appear red and inflamed. If you also snore loudly, are very tired all the time, or your bed partner has noticed that your breathing stops during sleep, speak with a doctor. Addressing the apnea and refitting the CPAP mask may alleviate both the eye and sleep symptoms.<br /><br /><h2>2. Dry Eye Syndrome<br /></h2><br />If your eyes aren't making enough tears — or the tears they do make aren't efficient — you might have dry eye syndrome. It can bring stinging, burning, redness, and blurred vision, particularly upon awakening.<br /><br />Sleeping with a ceiling fan, air conditioning, or heating vent blowing on your face will make it worse. Your sleeping position counts, too: side-sleepers sometimes keep one eye slightly ajar, allowing moisture to escape.<br /><br />Risk grows with age, contact lens wear, deficiency in vitamin A, and autoimmune conditions like lupus. Treatment extends from over-the-counter eye drops to prescription medicines that stimulate your eyes to produce more tears.<br /><br /><h2>3. Conjunctivitis (Pink Eye)<br /></h2><br />Pink eye isn't something to worry about in early childhood. Adults may wake up with red, irritated eyes caused by viral, bacterial, or allergic conjunctivitis. If there's discharge, the eyelids may be crusty in the morning. Red eyes without discharge are more likely from bacteria. Viral pink eye tends to result in watery discharge and swelling of the eyes. Allergic conjunctivitis can cause lots of itching.<br /><br />Bacterial and viral types are contagious, so washing your hands, with new towels, and no eye makeup are a must. Although antihistamines work well for allergic conjunctivitis, bacterial infections can be treated with antibiotic drops. Viral pink eye generally heals by itself, but cold compresses can relieve pain.<br /><br /><h2>4. Allergies at Work Overnight<br /></h2><br />Seasonal or environmental allergies may cause morning redness by inflaming the sensitive blood vessels in your eyes. Pollen, animal dander, dust mites, and mold spores will stick to your eyelashes and eyelids throughout the day. When you go to bed, these allergens are in direct contact with your eyes for several hours, causing morning irritation.<br /><br />The giveaway? Itching. When you wake up with eyes rubbing, allergens are often the offender. Pre-bedtime facial washes, allergen-proof bedclothes, and closed bedroom windows can help. In resistant situations, antihistamine eye drops are sometimes required.<br /><br /><h2>5. Ocular Rosacea (Eyelid Acne)<br /></h2><br />Yes, acne can indeed get on your eyelids. Ocular rosacea — a long-term inflammatory disorder — can cause eyelids to appear red, puffy, and irritated. It usually occurs in combination with facial rosacea but can appear on its own.<br /><br />People in their 30s to 50s are most commonly affected. Triggers include sun exposure, spicy foods, and hot beverages. While there’s no cure, symptoms can be managed with warm compresses, eyelid scrubs, and prescribed topical or oral medications. Treating the underlying rosacea can reduce morning redness and irritation.<br /><br /><h2>6. Glaucoma<br /></h2><br />Though uncommon, waking up with red eyes may indicate acute angle-closure glaucoma — a true emergency. It occurs when fluid accumulates quickly within the eye, causing intraocular pressure to shoot to perilous levels.<br /><br />In addition to redness, symptoms may involve intense pain in the eye, headache, blurred vision, nausea, and halos around lights. If left untreated immediately, this can result in permanent blindness in hours to days. If you ever find yourself with these symptoms, immediately seek ophthalmologic attention.<br /><br /><h2>7. Subconjunctival Hemorrhage<br /></h2><br />If ever you've awoken with a bright red eye but have no pain, you've probably had a subconjunctival hemorrhage — a ruptured blood vessel just beneath the surface.<br /><br />It appears scary but is generally not a problem. It may occur from coughing, sneezing, rubbing your eyes during sleep, or even from routine blinking. The blood will usually be reabsorbed in one to two weeks without medical intervention. Nevertheless, if it occurs over and over, an eye physician can test for underlying conditions such as high blood pressure or clotting disorders.<br /><br /><h2>When Should You Go See A Doctor?<br /></h2><br />Morning redness that happens occasionally and clears quickly may not be cause for concern. But if it becomes frequent, is accompanied by pain, discharge, blurred vision, or sensitivity to light, it’s worth getting checked.<br /><br />Your eyes have limited means of communicating distress, and redness is among them. Untreated, some causes — such as glaucoma or chronic dry eye — can cause permanent damage. A thorough eye exam will identify the issue and head off complications.<br /><br />Waking up with red eyes is no laughing matter. Whether it's the result of allergies, dryness, infection, or more severe eye disease, the sooner you know the cause, the sooner you can safeguard your vision. Simple tweaks, such as tweaking the sleep environment, keeping allergies at bay, or being compliant with chronic conditions, can pay dividends — both for your eye health and your morning routines.<br /><meta content="cms.next" name="cmsei" />

waking up with red eyes? 7 possible causes your body might be sending these warnings

Aarushi Bhadury

fugate

Blue Fugate Mystery

Surprising Blue Skin Condition

The Blue Family of Kentucky

Kentuckys Troublesome Creek

Blue Skin people

Although seeing uniquely colored people in cartoons and on screen, can you imagine seeing one in real life? It is not fiction, but blue people do exist. The Fugates, a family from rural Kentucky's Troublesome Creek, were well-known for their unique, blue-colored skin. People who met them often said they were "blue all over" or "as blue as Lake Louise." <br /><br />This wasn’t a one-off thing, this rare trait was passed down through their family. Their story became more widely known after a baby, Benjamin "Benjy" Stacy, was born with blue skin in 1975, prompting doctors to investigate the unusual phenomenon, according to the New York Post. <br /><br /><br /><h2>Family Mystery of Blue Skin Solved <br /></h2><br />When Benjy Stacy was born with a dark blue hue, doctors were baffled. The baby was transferred to a medical center, but physicians remained perplexed. That's when Benjy's grandmother offered a crucial clue, asking if they had ever heard of the "blue Fugates of Troublesome Creek." <br /><br />It was discovered that the baby was a descendant of this family, which traced its origins back to a French orphan named Martin Fugate who settled in Kentucky in 1820. Both Martin and his wife, Elizabeth Smart, unknowingly carried a rare recessive gene for a condition called methemoglobinemia. <br /><br /><br /><h2>What Causes One’s Skin To Turn Blue? <br /></h2><br />The Jamaica Hospital Medical Center methemoglobinemia is a rare blood disorder where red blood cells contain an unusually high amount of methemoglobin. Unlike normal hemoglobin, methemoglobin cannot carry oxygen effectively to the body's tissues. This lack of oxygenation gives the blood a dark, chocolate-like color, which, in turn, makes the skin appear blue and the lips purple. <br /><br />The Fugate family's isolated community and intermarriage over generations led to the persistence of this recessive gene, ensuring that the condition was passed down. One notable descendant, Luna Fugate, was described as "the bluest woman I ever saw." <br /><br />Methemoglobinemia can be either inherited, like in the Fugate family, or it can be acquired. Acquired cases are more common and are typically caused by exposure to certain medications or chemicals, such as nitrates, silver, or benzocaine. Symptoms of this rare disease can include: <br /><br /><ul><li>Bluish-colored skin</li><li>Seizures</li><li>Headaches</li><li>Shortness of breath</li><li>Fatigue</li></ul><br /><br /><h2>Can You Cure This Blue Skin-Condition? <br /></h2><br />In the early 1960s, two Fugate family members, who had grown tired of their blue appearance, sought medical help. A hematologist named Madison Cawein diagnosed their condition and found a simple but effective treatment: methylene blue dye. When ingested, this dye helps the body convert the dysfunctional methemoglobin back into regular hemoglobin. <br /><br />Within minutes of taking the dose, the Fugates' skin would turn a normal pinkish color. This solution provided a way to manage the condition and effectively “cured” them of their blue hue. Benjy Stacy, the last known living descendant with the trait, lost his blue coloration by age seven, though his lips and fingertips still turn blue when he is cold. <br /><br /><br /><h2>Are There Other Conditions That Cause Blue Skin? <br /></h2><br />Another condition that can cause the skin to turn a bluish or silver color is argyria. This is a different disorder from methemoglobinemia and is caused by prolonged contact with silver compounds or ingesting silver salts. People at risk for argyria include those who:<br /><br /><ul><li>Take medications with silver salts as an ingredient.</li><li>Use colloidal silver as a dietary supplement.</li><li>Have jobs that expose them to silver, such as silver mining or refining.</li></ul><br />A famous modern case was Paul Karason, known as "Papa Smurf," who developed argyria after drinking a homemade colloidal silver mixture and using a silver-based salve. His story helped raise awareness about the potential dangers of ingesting silver products.<br /><meta content="cms.next" name="cmsei" />